{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T13:17:37Z","timestamp":1781011057485,"version":"3.54.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]},{"name":"China\u2013Australia International Research Centre for Chinese Medicine and Foundation for Chinese Medicine and Technology Research of Guangdong Provincial Hospital of Chinese Medicine","award":["2017KT1820, 2016KT1571"],"award-info":[{"award-number":["2017KT1820, 2016KT1571"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Med Ther"],"DOI":"10.1186\/s12906-025-04895-x","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T08:55:34Z","timestamp":1746521734000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chinese herbal medicines for rhinosinusitis: a text-mining study with comparisons to contemporary research and clinical guidance"],"prefix":"10.1186","volume":"25","author":[{"given":"Jing","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian H.","family":"May","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenmin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiulan","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony Lin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfeng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanjian","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlie C.","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"4895_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4193\/Rhino12.000","volume":"50","author":"WJ Fokkens","year":"2012","unstructured":"Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, et al. European position paper on rhinosinusitis and nasal polyps 2012. Rhinology - Supplement. 2012;50:1\u2013298.","journal-title":"Rhinology - Supplement"},{"issue":"(Suppl S29)","key":"4895_CR2","first-page":"1","volume":"58","author":"WJ Fokkens","year":"2020","unstructured":"Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, et al. European position paper on rhinosinusitis and nasal polyps 2020. Rhinology. 2020;58(Suppl S29):1\u2013464.","journal-title":"Rhinology."},{"issue":"2 Suppl","key":"4895_CR3","first-page":"S1","volume":"152","author":"RM Rosenfeld","year":"2015","unstructured":"Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Ashok Kumar K, Kramper M, et al. Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg. 2015;152(2 Suppl):S1\u201339.","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"3","key":"4895_CR4","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.wjorl.2018.08.003","volume":"4","author":"MA Tyler","year":"2018","unstructured":"Tyler MA, Luong AU. Current understanding of allergic fungal rhinosinusitis. World J Otorhinolaryngol Head Neck Surg. 2018;4(3):179\u201385.","journal-title":"World J Otorhinolaryngol Head Neck Surg"},{"key":"4895_CR5","unstructured":"Subspecialty Group of Rhinology - Society of Otorhinolaryngology Head and Neck Surgery - Chinese Medical Association. Chinese guidelines for diagnosis and treatment of chronic rhinosinusitis (2012, Kunming). Chin J Otorhinolaryngol Head Neck Surg [Zhonghua er bi yan hou tou jing wai ke za zhi]. 2013;48(2):92\u20134."},{"issue":"5","key":"4895_CR6","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1007\/s00405-022-07762-4","volume":"280","author":"J Maza-Solano","year":"2023","unstructured":"Maza-Solano J, Biadsee A, Sowerby LJ, Calvo-Hernandez C, Tucciarone M, Rocha T, et al. Chronic rhinosinusitis with nasal polyps management in the biologic therapy era: an international YO-IFOS survey. Eur Arch Otorhinolaryngol. 2023;280(5):2309\u201316.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"4895_CR7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c2096","volume":"340","author":"C Costelloe","year":"2010","unstructured":"Costelloe C, Metcalfe C, Lovering A, Mant D, Hay AD. Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis. BMJ. 2010;340: c2096.","journal-title":"BMJ"},{"issue":"9","key":"4895_CR8","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1136\/bmjqs.2010.049049","volume":"20","author":"N Adriaenssens","year":"2011","unstructured":"Adriaenssens N, Coenen S, Tonkin-Crine S, Verheij TJM, Little P, Goossens H, et al. European Surveillance of Antimicrobial Consumption (ESAC): disease-specific quality indicators for outpatient antibiotic prescribing. BMJ Qual Saf. 2011;20(9):764\u201372.","journal-title":"BMJ Qual Saf"},{"key":"4895_CR9","unstructured":"State of Administration of Traditional Chinese Medicine. Criteria of diagnosis and therapeutic effect of diseases and syndromes in traditional Chinese medicine [ZY\/T001.1~001.9\u201394]. Nanjing: Nanjing University Press; 1994."},{"key":"4895_CR10","unstructured":"Subspecialty Group of Rhinology - Society of Otorhinolaryngology Head and Neck Surgery - Chinese Medical Association. Chinese guidelines for diagnosis and treatment of chronic rhinosinusitis (2018). Chin J Otorhinolaryngol Head Neck Surg. 2019;54(2):81\u2013100."},{"key":"4895_CR11","unstructured":"China Association of Traditional Chinese Medicine [Zhonghua zhong yiyao xuehui]. Guidelines for the diagnosis and treatment of common diseases of otolaryngology using traditional Chinese medicine [Zhongyi erbi yanhou ke changjian bing zhenliao zhenan]. Beijing: Traditional Chinese Medicine Press [Zhong yiyao chuban she]; 2012."},{"key":"4895_CR12","unstructured":"Office of the State Council of China. 2021 Statistical bulletin on the development of my country's health and wellness. In: Office of the State Council of China, editor. Beijing: 2022.\u00a0www.gov.cn\/xinwen\/2022-07\/12\/content_5700670.htm. Accessed 7 Dec 2022."},{"issue":"2","key":"4895_CR13","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1089\/acm.2017.29019.jjw","volume":"23","author":"J Weeks","year":"2017","unstructured":"Weeks J. Chinese TCM renaissance and the global movement for integrative health and medicine. J Altern Complement Med. 2017;23(2):79\u201381.","journal-title":"J Altern Complement Med"},{"issue":"1","key":"4895_CR14","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.drudis.2013.07.016","volume":"19","author":"A Helmstadter","year":"2014","unstructured":"Helmstadter A, Staiger C. Traditional use of medicinal agents: a valid source of evidence. Drug Discov Today. 2014;19(1):4\u20137.","journal-title":"Drug Discov Today"},{"issue":"2","key":"4895_CR15","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.glohj.2019.06.005","volume":"3","author":"CC Xue","year":"2019","unstructured":"Xue CC, Lyu Y. Accelerating the comprehensive and systematic evaluation of clinical evidence for Chinese medicine using a whole evidence approach. Global Health Journal. 2019;3(2):33\u20136.","journal-title":"Global Health Journal"},{"issue":"9","key":"4895_CR16","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1016\/j.tips.2004.07.003","volume":"25","author":"EJ Buenz","year":"2004","unstructured":"Buenz EJ, Schnepple DJ, Bauer BA, Elkin PL, Riddle JM, Motley TJ. Techniques: Bioprospecting historical herbal texts by hunting for new leads in old tomes. Trends Pharmacol Sci. 2004;25(9):494\u20138.","journal-title":"Trends Pharmacol Sci"},{"issue":"7582","key":"4895_CR17","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1136\/bmj.39008.492361.BE","volume":"333","author":"EJ Buenz","year":"2006","unstructured":"Buenz EJ, Bauer BA, Johnson HE, Tavana G, Beekman EM, Frank KL, et al. Searching historical herbal texts for potential new drugs. BMJ. 2006;333(7582):1314\u20135.","journal-title":"BMJ"},{"issue":"23\u201324","key":"4895_CR18","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.drudis.2011.07.002","volume":"16","author":"F Watkins","year":"2011","unstructured":"Watkins F, Pendry B, Corcoran O, Sanchez-Medina A. Anglo-Saxon pharmacopoeia revisited: a potential treasure in drug discovery. Drug Discov Today. 2011;16(23\u201324):1069\u201375.","journal-title":"Drug Discov Today"},{"issue":"1","key":"4895_CR19","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.jep.2010.05.035","volume":"132","author":"P De Vos","year":"2010","unstructured":"De Vos P. European materia medica in historical texts: Longevity of a tradition and implications for future use. J Ethnopharmacol. 2010;132(1):28\u201347.","journal-title":"J Ethnopharmacol"},{"issue":"3","key":"4895_CR20","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.jep.2008.11.010","volume":"121","author":"M Adams","year":"2009","unstructured":"Adams M, Berset C, Kessler M, Hamburger M. Medicinal herbs for the treatment of rheumatic disorders\u2013a survey of European herbals from the 16th and 17th century. J Ethnopharmacol. 2009;121(3):343\u201359.","journal-title":"J Ethnopharmacol"},{"key":"4895_CR21","doi-asserted-by":"publisher","first-page":"1798364","DOI":"10.1155\/2019\/1798364","volume":"2019","author":"HW Bae","year":"2019","unstructured":"Bae HW, Lee SY, Kim SJ, Shin HK, Choi BT, Baek JU. Selecting effective herbal medicines for attention-deficit\/hyperactivity disorder via text mining of Donguibogam. Evid Based Complement Alternat Med. 2019;2019:1798364.","journal-title":"Evid Based Complement Alternat Med"},{"key":"4895_CR22","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/873185","volume":"2015","author":"MJ Choi","year":"2015","unstructured":"Choi MJ, Choi BT, Shin HK, Shin BC, Han YK, Baek JU. Establishment of a comprehensive list of candidate antiaging medicinal herb used in Korean medicine by text mining of the classical Korean medical literature, \u201cdongeuibogam,\u201d and preliminary evaluation of the antiaging effects of these herbs. Evid Based Complement Alternat Med. 2015;2015: 873185.","journal-title":"Evid Based Complement Alternat Med"},{"issue":"3","key":"4895_CR23","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s10522-012-9375-6","volume":"13","author":"BH May","year":"2012","unstructured":"May BH, Lu C, Bennett L, Hugel HM, Xue CC. Evaluating the traditional Chinese literature for herbal formulae and individual herbs used for age-related dementia and memory impairment. Biogerontology. 2012;13(3):299\u2013312.","journal-title":"Biogerontology"},{"issue":"1","key":"4895_CR24","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.jams.2012.11.009","volume":"6","author":"BH May","year":"2013","unstructured":"May BH, Lu C, Lu Y, Zhang AL, Xue CC. Chinese herbs for memory disorders: a review and systematic analysis of classical herbal literature. J Acupunct Meridian Stud. 2013;6(1):2\u201311.","journal-title":"J Acupunct Meridian Stud"},{"key":"4895_CR25","doi-asserted-by":"crossref","unstructured":"Zhang L, Li Y, Guo XF, May BH, Xue CCL, Yang LH, et al. Text mining of the classical medical literature for medicines that show potential in diabetic nephropathy. Evid-Based Compl Alt. 2014;2014:189125. p 1\u201312.","DOI":"10.1155\/2014\/189125"},{"issue":"3","key":"4895_CR26","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1177\/1479972315583043","volume":"12","author":"JL Shergis","year":"2015","unstructured":"Shergis JL, Wu L, May BH, Zhang AL, Guo X, Lu C, et al. Natural products for chronic cough: Text mining the East Asian historical literature for future therapeutics. Chron Respir Dis. 2015;12(3):204\u201311.","journal-title":"Chron Respir Dis"},{"issue":"9","key":"4895_CR27","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1089\/acm.2016.0070","volume":"22","author":"BH May","year":"2016","unstructured":"May BH, Feng M, Zhou IW, Chang SY, Lu SC, Zhang AL, et al. Memory impairment, dementia, and Alzheimer\u2019s disease in classical and contemporary traditional Chinese medicine. J Altern Complement Med. 2016;22(9):695\u2013705.","journal-title":"J Altern Complement Med"},{"key":"4895_CR28","doi-asserted-by":"publisher","first-page":"7531967","DOI":"10.1155\/2020\/7531967","volume":"2020","author":"X Xia","year":"2020","unstructured":"Xia X, May BH, Zhang AL, Guo X, Lu C, Xue CC, et al. Chinese herbal medicines for rheumatoid arthritis: Text-mining the classical literature for potentially effective natural products. Evid Based Complement Alternat Med. 2020;2020:7531967.","journal-title":"Evid Based Complement Alternat Med"},{"key":"4895_CR29","volume-title":"Zhong Hua Yi Dian \u2018Encyclopaedia of traditional Chinese medicine\u2019","year":"2014","unstructured":"Hu R, editor. Zhong Hua Yi Dian \u2018Encyclopaedia of traditional Chinese medicine.\u2019 5th ed. Changsha: Hunan Electronic and Audio-Visual Publishing House; 2014.","edition":"5"},{"issue":"12","key":"4895_CR30","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1089\/acm.2011.0587","volume":"18","author":"BH May","year":"2012","unstructured":"May BH, Lu CJ, Xue CCL. Collections of traditional Chinese medical literature as resources for systematic searches. J Altern Complem Med. 2012;18(12):1101\u20137.","journal-title":"J Altern Complem Med"},{"issue":"5","key":"4895_CR31","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1089\/acm.2011.0919","volume":"19","author":"BH May","year":"2013","unstructured":"May BH, Lu YB, Lu CJ, Zhang AL, Chang SY, Xue CCL. Systematic assessment of the representativeness of published collections of the traditional literature on Chinese medicine. J Altern Complem Med. 2013;19(5):403\u20139.","journal-title":"J Altern Complem Med"},{"issue":"12","key":"4895_CR32","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1089\/acm.2013.0372","volume":"20","author":"BH May","year":"2014","unstructured":"May BH, Zhang A, Lu Y, Lu C, Xue CC. The systematic assessment of traditional evidence from the premodern Chinese medical literature: a text-mining approach. J Altern Complement Med. 2014;20(12):937\u201342.","journal-title":"J Altern Complement Med"},{"key":"4895_CR33","volume-title":"Zhong yi da ci dian 'Great dictionary of Chinese medicine'","year":"2005","unstructured":"Li JW, Yu YA, Cai JF, Zhang ZB, Ou YX, Deng TT, et al editors. Zhong yi da ci dian \u201cGreat dictionary of Chinese medicine.\u201d 2nd ed. Beijing: People\u2019s Medical Publishing House; 2005.","edition":"2"},{"key":"4895_CR34","unstructured":"Lin ZG, editor. Zhong xi yi bing ming dui zhao da ci dian 'Great dictionary of comparisons between Chinese and Western medical terms'. Beijing: Ren min wei sheng chu ban sha; 2002."},{"key":"4895_CR35","volume-title":"Pharmacopoeia of the People's Republic of China [Zhong hua ren min gong he guo yao dian]","author":"Chinese Pharmacopoeia Commission","year":"2020","unstructured":"Chinese Pharmacopoeia Commission. Pharmacopoeia of the People\u2019s Republic of China [Zhong hua ren min gong he guo yao dian]. Beijing: China Medical Science Press; 2020."},{"issue":"12","key":"4895_CR36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0278492","volume":"17","author":"J Cui","year":"2022","unstructured":"Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al. Chinese herbal therapy in the management of rhinosinusitis-A systematic review and meta-analysis. PLoS ONE. 2022;17(12): e0278492.","journal-title":"PLoS ONE"},{"issue":"10","key":"4895_CR37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0292138","volume":"18","author":"J Cui","year":"2023","unstructured":"Cui J, Lin W, May BH, Luo Q, Worsnop C, Zhang AL, et al. Orally administered Chinese herbal therapy to assist post-surgical recovery for chronic rhinosinusitis-A systematic review and meta-analysis. PLoS ONE. 2023;18(10): e0292138.","journal-title":"PLoS ONE"},{"key":"4895_CR38","unstructured":"May BH, Lin W, Zhang AL, Xue CC, Luo QL, Li Y, et al. Evidence-based clinical Chinese medicine volume 25: Rhinosinusitis, chapters 5 and 6. Singapore: World Scientific Publishing Co; 2022."},{"key":"4895_CR39","unstructured":"Needham J, Lu G. Science and civilisation in China, vol 6 part VI: Medicine. Cambridge: Cambridge University Press; 2000."},{"key":"4895_CR40","unstructured":"Yamada K. The origins of acupuncture, moxibustion and decoction. Kyoto: Nichibunken; 1998. 154 p."},{"key":"4895_CR41","volume-title":"Huang di nei jing su wen: An annotated translation of Huang Di's inner classic - basic questions","author":"PU Unschuld","year":"2011","unstructured":"Unschuld PU, Tessenow H. Huang di nei jing su wen: An annotated translation of Huang Di\u2019s inner classic - basic questions. Berkley: University of California Press; 2011."},{"key":"4895_CR42","unstructured":"Wai Ke Zheng Zong. Chongchuan: Chen Family. [Internet]. Library of Congress. 1617. Available from: Pdf. Retrieved from the Library of Congress, <www.loc.gov\/item\/2021666473\/>. Accessed 25 Sept 2023."},{"key":"4895_CR43","unstructured":"Jiangsu New Medical Academy, editor. Zhong yao da ci dian \u201cGreat compendium of Chinese medicines.\u201d Shanghai: Shanghai Scientific and Technical Publishers; 1986."},{"key":"4895_CR44","unstructured":"State Administration of Traditional Chinese Medicine 'Chinese Materia Medica Committee', editor. Zhong hua ben cao: jing xuan ben \u2018Chinese materia medica: abridged version\u2019. Shanghai: Shanghai Scientific and Technical Publishers; 1998."},{"key":"4895_CR45","doi-asserted-by":"crossref","unstructured":"Liu J, Bi Y, Luo R, Wu X. Simultaneous UFLC-ESI-MS\/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: application to pharmacokinetic studies in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879(27):2885\u201390.","DOI":"10.1016\/j.jchromb.2011.08.018"},{"issue":"8","key":"4895_CR46","first-page":"608","volume":"3","author":"P Veeru","year":"2009","unstructured":"Veeru P, Kishor MP, Meenakshi M. Screening of medicinal plant extracts for antioxidant activity. J Med Plants Res. 2009;3(8):608\u201312.","journal-title":"J Med Plants Res"},{"issue":"6","key":"4895_CR47","first-page":"4357","volume":"20","author":"MJ Bhitre","year":"2008","unstructured":"Bhitre MJ, Fulmali S, Kataria M, Anwikar S, Kadri H. Antiinflammatory activity of the fruits of Piper longum Linn. Asian J Chem. 2008;20(6):4357\u201360.","journal-title":"Asian J Chem"},{"issue":"5","key":"4895_CR48","doi-asserted-by":"publisher","first-page":"400","DOI":"10.3923\/ijp.2007.400.405","volume":"3","author":"Y Vaghasiya","year":"2007","unstructured":"Vaghasiya Y, Nair R, Chanda S. Investigation of some piper species for anti-bacterial and anti-inflammatory property. Int J Pharmacol. 2007;3(5):400\u20135.","journal-title":"Int J Pharmacol"},{"issue":"4","key":"4895_CR49","doi-asserted-by":"publisher","first-page":"454","DOI":"10.4103\/0250-474X.57300","volume":"71","author":"A Kumar","year":"2009","unstructured":"Kumar A, Panghal S, Mallapur SS, Kumar M, Ram V, Singh BK. Antiinflammatory activity of Piper longum fruit oil. Indian J Pharm Sci. 2009;71(4):454\u20136.","journal-title":"Indian J Pharm Sci"},{"issue":"2","key":"4895_CR50","doi-asserted-by":"publisher","first-page":"307","DOI":"10.4103\/0974-8520.105258","volume":"33","author":"M Kumari","year":"2012","unstructured":"Kumari M, Ashok BK, Ravishankar B, Pandya TN, Acharya R. Anti-inflammatory activity of two varieties of Pippali (Piper longum Linn.). Ayu. 2012;33(2):307\u201310.","journal-title":"Ayu (An international quarterly journal of research in Ayurveda)"},{"issue":"10","key":"4895_CR51","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.3109\/13880209.2014.991835","volume":"53","author":"Y Bi","year":"2015","unstructured":"Bi Y, Qu PC, Wang QS, Zheng L, Liu HL, Luo R, et al. Neuroprotective effects of alkaloids from Piper longum in a MPTP-induced mouse model of Parkinson\u2019s disease. Pharm Biol. 2015;53(10):1516\u201324.","journal-title":"Pharm Biol"},{"issue":"1","key":"4895_CR52","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1186\/s12906-016-1392-6","volume":"16","author":"H He","year":"2016","unstructured":"He H, Guo WW, Xu RR, Chen XQ, Zhang N, Wu X, et al. Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide. BMC Complement Altern Med. 2016;16(1):412.","journal-title":"BMC Complement Altern Med"},{"issue":"10","key":"4895_CR53","doi-asserted-by":"publisher","first-page":"2557","DOI":"10.13359\/j.cnki.gzxbtcm.2024.10.007","volume":"41","author":"CC Xue","year":"2024","unstructured":"Xue CC, Zhang AL, May BH, Pobjoy M, Zhou IW. Evidence-based clinical Chinese medicine: what has changed over the past 20 years. J Guangzhou Uni TCM. 2024;41(10):2557\u201371. https:\/\/doi.org\/10.13359\/j.cnki.gzxbtcm.2024.10.007.","journal-title":"J Guangzhou Uni TCM"}],"container-title":["BMC Complementary Medicine and Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-025-04895-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12906-025-04895-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-025-04895-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T08:55:51Z","timestamp":1746521751000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/s12906-025-04895-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,6]]},"references-count":53,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4895"],"URL":"https:\/\/doi.org\/10.1186\/s12906-025-04895-x","relation":{},"ISSN":["2662-7671"],"issn-type":[{"value":"2662-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,6]]},"assertion":[{"value":"8 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"165"}}