{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:40:02Z","timestamp":1791258002676,"version":"4.1.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Med Ther"],"DOI":"10.1186\/s12906-025-04993-w","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T08:48:24Z","timestamp":1752137304000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The screened triterpene acids from Loquat fruit by CysLTR1-immobilized column could serve as alternative anti-inflammatory agents"],"prefix":"10.1186","volume":"25","author":[{"given":"Tian","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YiFan","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YiYing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YiLong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DaLong","family":"Zhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ChaoNi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"issue":"23","key":"4993_CR1","doi-asserted-by":"publisher","first-page":"2749","DOI":"10.1016\/j.lfs.2005.10.040","volume":"78","author":"Y Huang","year":"2006","unstructured":"Huang Y, Li J, Cao Q, Yu SC, Lv XW, Jin Y, Zhang L, Zou YH, Ge JF. Anti-oxidative effect of triterpene acids of Eriobotrya japonica (Thunb.) lindl. Leaf in chronic bronchitis rats. Life Sci. 2006;78(23):2749\u201357.","journal-title":"Life Sci"},{"issue":"2","key":"4993_CR2","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1007\/s00011-006-5185-0","volume":"56","author":"Y Huang","year":"2007","unstructured":"Huang Y, Li J, Wang R, Wu Q, Li YH, Yu SC, Cheng WM, Wang YY. Effect of triterpene acids of Eriobotrya japonica (Thunb.) lindl. Leaf on inflammatory cytokine and mediator induction from alveolar macrophages of chronic bronchitic rats. Inflamm Res. 2007;56(2):76\u201382.","journal-title":"Inflamm Res"},{"issue":"6","key":"4993_CR3","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1142\/S0192415X09007521","volume":"37","author":"Y Huang","year":"2009","unstructured":"Huang Y, Li J, Meng XM, Jiang GL, Li H, Cao Q, Yu SC, Lv XW, Cheng WM. Effect of triterpene acids of Eriobotrya japonica (Thunb.) lindl. Leaf and MAPK signal transduction pathway on inducible nitric oxide synthase expression in alveolar macrophage of chronic bronchitis rats. Am J Chin Med. 2009;37(6):1099\u2013111.","journal-title":"Am J Chin Med"},{"issue":"2","key":"4993_CR4","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1142\/S0192415X09006862","volume":"37","author":"JF Ge","year":"2009","unstructured":"Ge JF, Wang TY, Zhao B, Lv XW, Jin Y, Peng L, Yu SC, Li J. Anti-inflammatory effect of triterpenoic acids of Eriobotrya japonica (Thunb.) lindl. Leaf on rat model of chronic bronchitis. Am J Chin Med. 2009;37(2):309\u201321.","journal-title":"Am J Chin Med"},{"issue":"4","key":"4993_CR5","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1016\/j.foodchem.2007.10.025","volume":"107","author":"JY Lin","year":"2008","unstructured":"Lin JY, Tang CY. Strawberry, loquat, mulberry, and bitter melon juices exhibit prophylactic effects on LPS-induced inflammation using murine peritoneal macrophages. Food Chem. 2008;107(4):1587\u201396.","journal-title":"Food Chem"},{"key":"4993_CR6","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/j.jff.2013.11.019","volume":"6","author":"PPK Zar","year":"2014","unstructured":"Zar PPK, Morishita A, Hashimoto F, Sakao K, Fujii M, Wada K, Hou DX. Anti-inflammatory effects and molecular mechanisms of Loquat (Eriobotrya japonica) tea. J Funct Food. 2014;6:523\u201333.","journal-title":"J Funct Food"},{"key":"4993_CR7","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.jep.2019.01.037","volume":"242","author":"J Zhang","year":"2019","unstructured":"Zhang J, Xu HY, Wu YJ, Zhang X, Zhang LQ, Li YM. Neutrophil elastase inhibitory effects of pentacyclic triterpenoids from Eriobotrya japonica (loquat leaves). J Ethnopharmacol. 2019;242:8.","journal-title":"J Ethnopharmacol"},{"issue":"5","key":"4993_CR8","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1248\/cpb.48.687","volume":"48","author":"H Ito","year":"2000","unstructured":"Ito H, Kobayashi E, Takamatsu Y, Li SH, Hatano T, Sakagami H, Kusama K, Satoh K, Sugita D, Shimura S, Itoh Y, Yoshida T. Polyphenols from Eriobotrya japonica and their cytotoxicity against human oral tumor cell lines. Chem Pharm Bull. 2000;48(5):687\u201393.","journal-title":"Chem Pharm Bull"},{"issue":"3","key":"4993_CR9","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/S1016-8478(23)17470-X","volume":"10","author":"HJ Kwon","year":"2000","unstructured":"Kwon HJ, Kang MJ, Kim HJ, Choi JS, Paik KJ, Chung HY. Inhibition of NF\u03baB by methyl chlorogenate from Eriobotrya japonica. Mol Cells. 2000;10(3):241\u20136.","journal-title":"Mol Cells"},{"issue":"6","key":"4993_CR10","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1021\/np010004x","volume":"64","author":"H Ito","year":"2001","unstructured":"Ito H, Kobayashi E, Li SH, Hatano T, Sugita D, Kubo N, Shimura S, Itoh Y, Yoshida T. Megastigmane glycosides and an acylated triterpenoid from Eriobotrya japonica. J Nat Prod. 2001;64(6):737\u201340.","journal-title":"J Nat Prod"},{"issue":"8","key":"4993_CR11","doi-asserted-by":"publisher","first-page":"2400","DOI":"10.1021\/jf011083l","volume":"50","author":"H Ito","year":"2002","unstructured":"Ito H, Kobayashi E, Li SH, Hatano T, Sugita D, Kubo N, Shimura S, Itoh Y, Tokuda H, Nishino H, Yoshida T. Antitumor activity of compounds isolated from leaves of Eriobotrya japonicai. J Agric Food Chem. 2002;50(8):2400\u20133.","journal-title":"J Agric Food Chem"},{"issue":"12","key":"4993_CR12","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3390\/ijms17121983","volume":"17","author":"YL Liu","year":"2016","unstructured":"Liu YL, Zhang WN, Xu CJ, Li X. Biological activities of extracts from Loquat (Eriobotrya Japonica Lindl.): a review. Int J Mol Sci. 2016;17(12):15.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"4993_CR13","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.jep.2010.12.017","volume":"134","author":"DS Cha","year":"2011","unstructured":"Cha DS, Eun JS, Jeon H. Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica. J Ethnopharmacol. 2011;134(2):305\u201312.","journal-title":"J Ethnopharmacol"},{"issue":"10","key":"4993_CR14","doi-asserted-by":"publisher","first-page":"1995","DOI":"10.1248\/bpb.28.1995","volume":"28","author":"N Banno","year":"2005","unstructured":"Banno N, Akihisa T, Tokuda H, Yasukawa K, Taguchi Y, Akazawa H, Ukiya M, Kimura Y, Suzuki T, Nishino H. Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica. Biol Pharm Bull. 2005;28(10):1995\u20139.","journal-title":"Biol Pharm Bull"},{"issue":"6738","key":"4993_CR15","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1038\/21658","volume":"399","author":"KR Lynch","year":"1999","unstructured":"Lynch KR, O\u2019Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z, Connolly BM, Bai C, Austin CP, Chateauneuf A, Stocco R, Greig GM, Kargman S, Hooks SB, Hosfield E, Williams DL Jr, Ford-Hutchinson AW, Caskey CT, Evans JF. Characterization of the human Cysteinyl leukotriene CysLT1 receptor. Nature. 1999;399(6738):789\u201393.","journal-title":"Nature"},{"issue":"1","key":"4993_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.phrs.2003.12.012","volume":"50","author":"V Capra","year":"2004","unstructured":"Capra V. Molecular and functional aspects of human Cysteinyl leukotriene receptors. Pharmacol Res. 2004;50(1):1\u201311.","journal-title":"Pharmacol Res"},{"issue":"14","key":"4993_CR17","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3390\/ijms20143580","volume":"20","author":"A Jo-Watanabe","year":"2019","unstructured":"Jo-Watanabe A, Okuno T, Yokomizo T. The role of leukotrienes as potential therapeutic targets in allergic disorders. Int J Mol Sci. 2019;20(14):21.","journal-title":"Int J Mol Sci"},{"issue":"1\u20133","key":"4993_CR18","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1159\/000237013","volume":"107","author":"JM Drazen","year":"1995","unstructured":"Drazen JM, Israel E. Treatment of chronic stable asthma with drugs active on the 5-lipoxygenase pathway. Int Arch Allergy Immunol. 1995;107(1\u20133):319\u201320.","journal-title":"Int Arch Allergy Immunol"},{"issue":"2","key":"4993_CR19","doi-asserted-by":"publisher","first-page":"S68","DOI":"10.1164\/ajrccm.161.supplement_1.ltta-14","volume":"161","author":"PM O\u2019Byrne","year":"2000","unstructured":"O\u2019Byrne PM. Leukotriene bronchoconstriction induced by allergen and exercise. Am J Respir Crit Care Med. 2000;161(2):S68\u201372.","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"4993_CR20","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1248\/cpb.c21-00040","volume":"69","author":"MA Arai","year":"2021","unstructured":"Arai MA. Target protein-oriented isolations for bioactive natural products. Chem Pharm Bull. 2021;69(6):503\u201315.","journal-title":"Chem Pharm Bull"},{"issue":"4","key":"4993_CR21","doi-asserted-by":"publisher","first-page":"313","DOI":"10.2174\/138920011795202938","volume":"12","author":"DS Hage","year":"2011","unstructured":"Hage DS, Anguizola J, Barnaby O, Jackson A, Yoo MJ, Papastavros E, Pfaunmiller E, Sobansky M, Tong ZH. Characterization of drug interactions with serum proteins by using high-performance affinity chromatography. Curr Drug Metab. 2011;12(4):313\u201328.","journal-title":"Curr Drug Metab"},{"issue":"2","key":"4993_CR22","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.ab.2007.02.014","volume":"364","author":"R Moaddel","year":"2007","unstructured":"Moaddel R, Calleri E, Massolini G, Frazier CR, Wainer IW. The synthesis and initial characterization of an immobilized purinergic receptor (P2Y(1)) liquid chromatography stationary phase for online screening. Anal Biochem. 2007;364(2):216\u20138.","journal-title":"Anal Biochem"},{"issue":"1","key":"4993_CR23","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ab.2010.12.034","volume":"412","author":"R Moaddel","year":"2011","unstructured":"Moaddel R, Rosenberg A, Spelman K, Frazier J, Frazier C, Nocerino S, Brizzi A, Mugnaini C, Wainer IW. Development and characterization of immobilized cannabinoid receptor (CB1\/CB2) open tubular column for on-line screening. Anal Biochem. 2011;412(1):85\u201391.","journal-title":"Anal Biochem"},{"issue":"12","key":"4993_CR24","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.1111\/j.1745-7254.2006.00458.x","volume":"27","author":"J Zhang","year":"2006","unstructured":"Zhang J, Zhang L, Ye YL, Fang SH, Zhou Y, Zhang WP, Lu YB, Wei EQ. Cysteinyl leukotriene receptors CysLT1 and CysLT2 are upregulated in acute neuronal injury after focal cerebral ischemia in mice. Acta Pharmacol Sin. 2006;27(12):1553\u201360.","journal-title":"Acta Pharmacol Sin"},{"key":"4993_CR25","doi-asserted-by":"crossref","unstructured":"Li XC, Yang W, Li Y, Kang J, Wang J, Fang MF. Revealing the anti-inflammatory ingredients in wine-processed Radix et Rhizoma Rhei using immobilized cysteinyl leukotriene receptor type 1 as the stationary phase. J Pharm Biomed Anal. 2024;242:10.","DOI":"10.1016\/j.jpba.2024.116036"},{"key":"4993_CR26","unstructured":"Commission NP. Chinese pharmacopoeia. China Medical Science and Technology Press:Beijing. 2020;1."},{"key":"4993_CR27","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.biopha.2023.114793","volume":"163","author":"L Wei","year":"2023","unstructured":"Wei L, Hongping H, Chufang L, Cuomu M, Jintao L, Kaiyin C, Lvyi C, Weiwu C, Zuguang Y, Nanshan Z. Effects of Shiwei Longdanhua formula on LPS induced airway mucus hypersecretion, cough hypersensitivity, oxidative stress and pulmonary inflammation. Biomed Pharmacother. 2023;163:11.","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"4993_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5625\/lar.2018.34.1.1","volume":"34","author":"SY Lee","year":"2018","unstructured":"Lee SY, Cho JH, Cho SS, Bae CS, Kim GY, Park DH. Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillation. Lab Anim Res. 2018;34(1):1\u201310.","journal-title":"Lab Anim Res"},{"issue":"3","key":"4993_CR29","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1124\/mol.56.3.657","volume":"56","author":"HM Sarau","year":"1999","unstructured":"Sarau HM, Ames RS, Chambers J, Ellis C, Elshourbagy N, Foley JJ, Schmidt DB, Muccitelli RM, Jenkins O, Murdock PR, Herrity NC, Halsey W, Sathe G, Muir AI, Nuthulaganti P, Dytko GM, Buckley PT, Wilson S, Bergsma DJ, Hay DW. Identification, molecular cloning, expression, and characterization of a Cysteinyl leukotriene receptor. Mol Pharmacol. 1999;56(3):657\u201363.","journal-title":"Mol Pharmacol"},{"issue":"6","key":"4993_CR30","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1021\/cb800025k","volume":"3","author":"GV Los","year":"2008","unstructured":"Los GV, Encell LP, McDougall MG, Hartzell DD, Karassina N, Zimprich C, Wood MG, Learish R, Ohana RF, Urh M, Simpson D, Mendez J, Zimmerman K, Otto P, Vidugiris G, Zhu J, Darzins A, Klaubert DH, Bulleit RF, Wood KV. HaloTag: a novel protein labeling technology for cell imaging and protein analysis. ACS Chem Biol. 2008;3(6):373\u201382.","journal-title":"ACS Chem Biol"},{"key":"4993_CR31","doi-asserted-by":"publisher","first-page":"465322","DOI":"10.1016\/j.chroma.2024.465322","volume":"1734","author":"T Wang","year":"2024","unstructured":"Wang T, Wang Y, Zhao S, Han Y, Li Q, Liu P, Li X, Xiao C. Target-specific affinity separation of the bioactive compounds from herbal extract using the spin column packed with the immobilized protein microspheres prior to LC-MS analysis. J Chromatogr A. 2024;1734:465322.","journal-title":"J Chromatogr A"},{"key":"4993_CR32","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.jchromb.2022.123409","volume":"1208","author":"R Xu","year":"2022","unstructured":"Xu R, Cheng PX, Meng KL, Li LK, Jiao MZ, Zhao X, Jia P, Zheng XH, Xiao CN. Extracellular domain of human calcium sensing receptor immobilized to silica beads as biomaterial: a rapid chromatographic method for recognizing ligands from complex matrix \u2018shuangdan\u2019. J Chromatogr B. 2022;1208:11.","journal-title":"J Chromatogr B"},{"key":"4993_CR33","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.foodchem.2022.133593","volume":"395","author":"X Zhao","year":"2022","unstructured":"Zhao X, Fu XY, Wang TT, Xu R, Shayiranbieke A, Zheng XX, Jia XN, Xiao CN, Zhao XF. Screening of bioactive flavour compounds targeting muscarinic-3 acetylcholine receptor from Siraitia grosvenorii and evaluation of their synergistic anti-asthmatic activity. Food Chem. 2022;395:10.","journal-title":"Food Chem"},{"issue":"12","key":"4993_CR34","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1002\/bmc.1614","volume":"25","author":"QH Chen","year":"2011","unstructured":"Chen QH, Zhang YL, Zhang WP, Chen ZL. Identification and quantification of oleanolic acid and ursolic acid in Chinese herbs by liquid chromatography-ion trap mass spectrometry. Biomed Chromatogr. 2011;25(12):1381\u201388.","journal-title":"Biomed Chromatogr"},{"issue":"7","key":"4993_CR35","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1002\/jms.1228","volume":"42","author":"LY Huang","year":"2007","unstructured":"Huang LY, Chen TW, Ye Z, Chen GN. Use of liquid chromatography-atmospheric pressure chemical ionization-ion trap mass spectrometry for identification of oleanolic acid and ursolic acid in Anoectochilus Roxburghii. (wall) Lindl J Mass Spectrom. 2007;42(7):910\u20137.","journal-title":"(wall) Lindl J Mass Spectrom"},{"issue":"15","key":"4993_CR36","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1055\/s-0030-1270993","volume":"77","author":"QW Liu","year":"2011","unstructured":"Liu QW, Zhao D, Chen XJ, Li ZB, Li N, Han D, Talbi A, Biwoele T. Determination of corosolic acid, a natural potential anti-diabetes compound, in rat plasma by high-performance liquid chromatography-mass spectrometry and its application to pharmacokinetic and bioavailability studies. Planta Med. 2011;77(15):1707\u201311.","journal-title":"Planta Med"},{"key":"4993_CR37","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3389\/fmed.2017.00106","volume":"4","author":"GA Thompson-Souza","year":"2017","unstructured":"Thompson-Souza GA, Gropillo I, Neves JS. Cysteinyl leukotrienes in eosinophil biology: functional roles and therapeutic perspectives in eosinophilic disorders. Front Med. 2017;4:8.","journal-title":"Front Med"},{"issue":"7","key":"4993_CR38","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1046\/j.1365-2222.2002.01425.x","volume":"32","author":"H Shirasaki","year":"2002","unstructured":"Shirasaki H, Kanaizumi E, Watanabe K, Matsui T, Sato J, Narita S, Rautiainen M, Himi T. Expression and localization of the Cysteinyl leukotriene 1 receptor in human nasal mucosa. Clin Exp Allergy. 2002;32(7):1007\u201312.","journal-title":"Clin Exp Allergy"},{"issue":"2","key":"4993_CR39","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1023\/A:1015384201785","volume":"18","author":"SJ Park","year":"2002","unstructured":"Park SJ, Lee SC, Hong SH, Kim HM. Degradation of I\u03baB\u03b1 in activated RAW264.7 cells is blocked by the phosphatidylinositol 3-kinase inhibitor LY294002. Cell Biol Toxicol. 2002;18(2):121\u201330.","journal-title":"Cell Biol Toxicol"},{"issue":"1 Suppl","key":"4993_CR40","doi-asserted-by":"publisher","first-page":"S37","DOI":"10.1067\/mai.2003.23","volume":"111","author":"M Peters-Golden","year":"2003","unstructured":"Peters-Golden M, Sampson AP. Cysteinyl leukotriene interactions with other mediators and with glucocorticosteroids during airway inflammation. J Allergy Clin Immunol. 2003;111(1 Suppl):S37\u201342.","journal-title":"J Allergy Clin Immunol"},{"issue":"11","key":"4993_CR41","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1164\/rccm.2109012","volume":"165","author":"S Nag","year":"2002","unstructured":"Nag S, Lamkhioued B, Renzi PM. Interleukin-2-induced increased airway responsiveness and lung Th2 cytokine expression occur after antigen challenge through the leukotriene pathway. Am J Respir Crit Care Med. 2002;165(11):1540\u20135.","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"4993_CR42","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2174\/1872213X10666160711143904","volume":"10","author":"D Kashyap","year":"2016","unstructured":"Kashyap D, Sharma A, Tuli HS, Punia S, Sharma AK. Ursolic acid and oleanolic acid: pentacyclic terpenoids with promising anti-inflammatory activities. Recent Pat Inflamm Allergy Drug Discov. 2016;10(1):21\u201333.","journal-title":"Recent Pat Inflamm Allergy Drug Discov"},{"issue":"13","key":"4993_CR43","doi-asserted-by":"publisher","first-page":"2263","DOI":"10.1080\/14786419.2019.1666385","volume":"35","author":"A Magiera","year":"2021","unstructured":"Magiera A, Marchelak A, Michel P, Owczarek A, Olszewska MA. Lipophilic extracts from leaves, inflorescences and fruits of Prunus padus L. as potential sources of corosolic, ursolic and oleanolic acids with anti-inflammatory activity. Nat Prod Res. 2021;35(13):2263\u20138.","journal-title":"Nat Prod Res"},{"issue":"2","key":"4993_CR44","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1142\/S0192415X09006862","volume":"37","author":"JF Ge","year":"2009","unstructured":"Ge JF, Wang TY, Zhao B, Lv XW, Jin Y, Peng L, Yu SC, Li J. Anti-inflammatory effect of triterpenoic acids of Eriobotrya japonica (Thunb.) lindl. Leaf on rat model of chronic bronchitis. Am J Chin Med. 2009;37(2):309\u201321.","journal-title":"Am J Chin Med"},{"issue":"3","key":"4993_CR45","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1016\/j.foodchem.2011.01.114","volume":"127","author":"CT Chang","year":"2011","unstructured":"Chang CT, Huang SS, Lin SS, Amagaya S, Ho HY, Hou WC, Shie PH, Wu JB, Huang GJ. Anti-inflammatory activities of tormentic acid from suspension cells of Eriobotrya Japonica ex vivo and in vivo. Food Chem. 2011;127(3):1131\u20137.","journal-title":"Food Chem"},{"key":"4993_CR46","doi-asserted-by":"crossref","unstructured":"Matsuyama M, Funao K, Chargui J, Touraine JL, Nakatani T, Yoshimura R. The role of cysteinyl-LT1 receptor (CysLT1R) in renal ischemia-reperfusion injury. Transplant Proc. 2009;41(1):73\u20135.","DOI":"10.1016\/j.transproceed.2008.08.153"},{"issue":"1","key":"4993_CR47","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1164\/ajrccm.163.1.2003101","volume":"163","author":"DJ Figueroa","year":"2001","unstructured":"Figueroa DJ, Breyer RM, Defoe SK, Kargman S, Daugherty BL, Waldburger K, Liu Q, Clements M, Zeng Z, O\u2019Neill GP, Jones TR, Lynch KR, Austin CP, Evans JF. Expression of the Cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytes. Am J Respir Crit Care Med. 2001;163(1):226\u201333.","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"4993_CR48","first-page":"1341","volume":"25","author":"YJ Zhang","year":"2004","unstructured":"Zhang YJ, Zhang L, Wang SB, Shen HH, Wei EQ. Montelukast modulates lung CysLT1 receptor expression and eosinophilic inflammation in asthmatic mice. Acta Pharmacol Sin. 2004;25(10):1341\u20136.","journal-title":"Acta Pharmacol Sin"}],"container-title":["BMC Complementary Medicine and Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-025-04993-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12906-025-04993-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-025-04993-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T09:29:16Z","timestamp":1752139756000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/s12906-025-04993-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,9]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4993"],"URL":"https:\/\/doi.org\/10.1186\/s12906-025-04993-w","relation":{},"ISSN":["2662-7671"],"issn-type":[{"value":"2662-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,9]]},"assertion":[{"value":"2 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Animal Care and Use Committee of Northwest University in China (Approval No: 2024\/13) and conducted in accordance with the National Institute of Health\u2019s Guidelines regarding the principles of animal care (PR China, 2023).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"249"}}