{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:50:50Z","timestamp":1791669050824,"version":"4.3.4"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"vor","delay-in-days":72,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Complement Med Ther"],"DOI":"10.1186\/s12906-026-05464-6","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T07:53:29Z","timestamp":1785398009000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolation and characterization of endophytic bacteria from Echinacea purpurea and Calendula officinalis with antimicrobial and anticancer activities"],"prefix":"10.1186","volume":"26","author":[{"given":"Razieh","family":"Mohseni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Shojaei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Sadegh","family":"Damavandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"issue":"1","key":"5464_CR1","doi-asserted-by":"publisher","first-page":"12878","DOI":"10.1038\/s41598-024-63535-5","volume":"14","author":"S Ghomashi","year":"2024","unstructured":"Ghomashi S, Ghomashi R, Damavandi MS, Fakhar Z, Mousavi SY, Salari-Jazi A, et al. Evaluation of antibacterial, cytotoxicity, and apoptosis activity of novel chromene-sulfonamide hybrids synthesized under solvent-free conditions and 3D-QSAR modeling studies. Sci Rep. 2024;14(1):12878.","journal-title":"Sci Rep"},{"issue":"10","key":"5464_CR2","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1038\/s41570-021-00313-1","volume":"5","author":"M Miethke","year":"2021","unstructured":"Miethke M, Pieroni M, Weber T, Br\u00f6nstrup M, Hammann P, Halby L, et al. Towards the sustainable discovery and development of new antibiotics. Nat Reviews Chem. 2021;5(10):726\u201349.","journal-title":"Nat Reviews Chem"},{"issue":"1","key":"5464_CR3","doi-asserted-by":"publisher","first-page":"16130","DOI":"10.1038\/s41598-022-20278-5","volume":"12","author":"H Seyedhosseini Ghaheh","year":"2022","unstructured":"Seyedhosseini Ghaheh H, Damavandi MS, Sadeghi P, Massah AR, Asl TH, Salari-Jazi A, et al. Targeting and ultrabroad insight into molecular basis of Resistance-nodulation-cell division efflux pumps. Sci Rep. 2022;12(1):16130.","journal-title":"Sci Rep"},{"issue":"1","key":"5464_CR4","doi-asserted-by":"publisher","first-page":"23734","DOI":"10.1038\/s41598-025-07627-w","volume":"15","author":"S Selim","year":"2025","unstructured":"Selim S, Moustafa MH, Almuhayawi MS, Gattan HS, Alruhaili MH, Alharbi MT, et al. Phytochemical profiling and evaluation of antioxidant, anticancer, antimicrobial and antibiofilm activities of endophytic fungi isolated from Lavandula stricta. Sci Rep. 2025;15(1):23734.","journal-title":"Sci Rep"},{"issue":"1","key":"5464_CR5","doi-asserted-by":"publisher","first-page":"18473","DOI":"10.1038\/s41598-023-45910-w","volume":"13","author":"MS Damavandi","year":"2023","unstructured":"Damavandi MS, Shojaei H, Esfahani BN. The anticancer and antibacterial potential of bioactive secondary metabolites derived from bacterial endophytes in association with Artemisia absinthium. Sci Rep. 2023;13(1):18473.","journal-title":"Sci Rep"},{"issue":"1","key":"5464_CR6","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1038\/s41598-022-05448-9","volume":"12","author":"K Georgousaki","year":"2022","unstructured":"Georgousaki K, Gonz\u00e1lez-Men\u00e9ndez V, Tormo JR, Tsafantakis N, Mackenzie TA, Mart\u00edn J, et al. Comoclathrin, a novel potent skin-whitening agent produced by endophytic Comoclathris strains associated with Andalusia desert plants. Sci Rep. 2022;12(1):1649.","journal-title":"Sci Rep"},{"key":"5464_CR7","doi-asserted-by":"publisher","first-page":"2951","DOI":"10.1007\/s00253-021-11212-2","volume":"105","author":"M Cardinale","year":"2021","unstructured":"Cardinale M, Viola M, Miceli E, Faddetta T, Puglia AM, Maggini V, et al. The cypsela (achene) of Echinacea purpurea as a diffusion unit of a community of microorganisms. Appl Microbiol Biotechnol. 2021;105:2951\u201365.","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"5464_CR8","doi-asserted-by":"publisher","first-page":"16924","DOI":"10.1038\/s41598-017-17110-w","volume":"7","author":"V Maggini","year":"2017","unstructured":"Maggini V, De Leo M, Mengoni A, Gallo ER, Miceli E, Reidel RVB, et al. Plant-endophytes interaction influences the secondary metabolism in Echinacea purpurea (L.) Moench: an in vitro model. Sci Rep. 2017;7(1):16924.","journal-title":"Sci Rep"},{"issue":"9","key":"5464_CR9","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.3390\/plants13091235","volume":"13","author":"F Ahmadi","year":"2024","unstructured":"Ahmadi F, Kariman K, Mousavi M, Rengel Z. Echinacea: Bioactive compounds and agronomy. Plants. 2024;13(9):1235.","journal-title":"Plants"},{"key":"5464_CR10","unstructured":"Latifian E, Arslano\u011flu \u015eF, editors. The medicinal plants cultivated in Iran. Congress Book; 2017."},{"issue":"1","key":"5464_CR11","doi-asserted-by":"publisher","first-page":"18236","DOI":"10.1038\/s41598-022-23073-4","volume":"12","author":"RA Mahdi","year":"2022","unstructured":"Mahdi RA, Bahrami Y, Kakaei E. Identification and antibacterial evaluation of endophytic actinobacteria from Luffa cylindrica. Sci Rep. 2022;12(1):18236.","journal-title":"Sci Rep"},{"issue":"7","key":"5464_CR12","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1093\/molbev\/msab120","volume":"38","author":"K Tamura","year":"2021","unstructured":"Tamura K, Stecher G, Kumar S. MEGA11: molecular evolutionary genetics analysis version 11. Mol Biol Evol. 2021;38(7):3022\u20137.","journal-title":"Mol Biol Evol"},{"issue":"12","key":"5464_CR13","doi-asserted-by":"publisher","first-page":"e914","DOI":"10.1002\/mbo3.914","volume":"8","author":"TE Sebola","year":"2019","unstructured":"Sebola TE, Uche-Okereafor NC, Tapfuma KI, Mekuto L, Green E, Mavumengwana V. Evaluating antibacterial and anticancer activity of crude extracts of bacterial endophytes from Crinum macowanii Baker bulbs. MicrobiologyOpen. 2019;8(12):e914.","journal-title":"MicrobiologyOpen"},{"key":"5464_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-020-03095-z","volume":"20","author":"CI Nxumalo","year":"2020","unstructured":"Nxumalo CI, Ngidi LS, Shandu JSE, Maliehe TS. Isolation of endophytic bacteria from the leaves of Anredera cordifolia CIX1 for metabolites and their biological activities. BMC Complement Med Ther. 2020;20:1\u201311.","journal-title":"BMC Complement Med Ther"},{"key":"5464_CR15","doi-asserted-by":"publisher","unstructured":"Zamani H, Salehzadeh A, Abdolhosseini M. Isolation and molecular identification of a cellulotic bacterium from muncipal waste and investigation of its cellulase production. Biosci J. 2018;34(3):761\u20138. https:\/\/doi.org\/10.14393\/BJ-v34n3a2018-40007.","DOI":"10.14393\/BJ-v34n3a2018-40007"},{"key":"5464_CR16","first-page":"1","volume":"1","author":"TEE Dela Cruz","year":"2012","unstructured":"Dela Cruz TEE, Torres JMO. Gelatin hydrolysis test protocol. Am Soc Microbiol. 2012;1:1\u201310.","journal-title":"Am Soc Microbiol"},{"issue":"3","key":"5464_CR17","doi-asserted-by":"publisher","first-page":"e0283677","DOI":"10.1371\/journal.pone.0283677","volume":"18","author":"H Mushtaq","year":"2023","unstructured":"Mushtaq H, Ganai SA, Jehangir A, Ganai BA, Dar R. Molecular and functional characterization of protease from psychrotrophic Bacillus sp. HM49 in North-western Himalaya. PLoS ONE. 2023;18(3):e0283677.","journal-title":"PLoS ONE"},{"issue":"1","key":"5464_CR18","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/S0141-0229(99)00125-8","volume":"26","author":"E Haba","year":"2000","unstructured":"Haba E, Bresco O, Ferrer C, Marques A, Busquets M, Manresa A. Isolation of lipase-secreting bacteria by deploying used frying oil as selective substrate. Enzym Microb Technol. 2000;26(1):40\u20134.","journal-title":"Enzym Microb Technol"},{"key":"5464_CR19","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing. CLSI supplement M100","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2022","unstructured":"Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing. CLSI supplement M100. 32nd ed. Wayne, PA: CLSI; 2022.","edition":"32"},{"issue":"1","key":"5464_CR20","doi-asserted-by":"publisher","first-page":"17302","DOI":"10.1038\/s41598-019-53227-w","volume":"9","author":"A Ranjan","year":"2019","unstructured":"Ranjan A, Singh RK, Khare S, Tripathi R, Pandey RK, Singh AK, et al. Characterization and evaluation of mycosterol secreted from endophytic strain of Gymnema sylvestre for inhibition of \u03b1-glucosidase activity. Sci Rep. 2019;9(1):17302.","journal-title":"Sci Rep"},{"issue":"1","key":"5464_CR21","doi-asserted-by":"publisher","first-page":"2733","DOI":"10.1038\/s41598-022-06711-9","volume":"12","author":"J Zhou","year":"2022","unstructured":"Zhou J, Feng Z, Zhang W, Xu J. Evaluation of the antimicrobial and cytotoxic potential of endophytic fungi extracts from mangrove plants Rhizophora stylosa and R. mucronata. Sci Rep. 2022;12(1):2733.","journal-title":"Sci Rep"},{"issue":"5","key":"5464_CR22","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s13205-020-02211-7","volume":"10","author":"TFB Santos","year":"2020","unstructured":"Santos TFB, dos Santos Carvalho C, de Almeida MA, Delforno TP, Duarte ICS. Endophytic fungi isolated from Brazilian medicinal plants as potential producers of antioxidants and their relations with anti-inflammatory activity. 3 Biotech. 2020;10(5):223.","journal-title":"3 Biotech"},{"key":"5464_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12870-019-1890-z","volume":"19","author":"V Maggini","year":"2019","unstructured":"Maggini V, Mengoni A, Gallo ER, Biffi S, Fani R, Firenzuoli F, et al. Tissue specificity and differential effects on in vitro plant growth of single bacterial endophytes isolated from the roots, leaves and rhizospheric soil of Echinacea purpurea. BMC Plant Biol. 2019;19:1\u20139.","journal-title":"BMC Plant Biol"},{"issue":"3","key":"5464_CR24","doi-asserted-by":"publisher","first-page":"336","DOI":"10.3934\/microbiol.2021021","volume":"7","author":"V Shurigin","year":"2021","unstructured":"Shurigin V, Alaylar B, Davranov K, Wirth S, Bellingrath-Kimura SD, Egamberdieva D. Diversity and biological activity of culturable endophytic bacteria associated with marigold (Calendula officinalis L). AIMS Microbiol. 2021;7(3):336.","journal-title":"AIMS Microbiol"},{"key":"5464_CR25","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.3389\/fmicb.2018.01555","volume":"9","author":"YY Loo","year":"2018","unstructured":"Loo YY, Rukayadi Y, Nor-Khaizura M-A-R, Kuan CH, Chieng BW, Nishibuchi M, et al. In vitro antimicrobial activity of green synthesized silver nanoparticles against selected gram-negative foodborne pathogens. Front Microbiol. 2018;9:1555.","journal-title":"Front Microbiol"},{"issue":"1","key":"5464_CR26","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1080\/17429145.2015.1056261","volume":"10","author":"H Li","year":"2015","unstructured":"Li H, Soares MA, Torres MS, Bergen M, White JF Jr. Endophytic bacterium, Bacillus amyloliquefaciens, enhances ornamental hosta resistance to diseases and insect pests. J Plant Interact. 2015;10(1):224\u20139.","journal-title":"J Plant Interact"},{"key":"5464_CR27","doi-asserted-by":"publisher","first-page":"102125","DOI":"10.1016\/j.bcab.2021.102125","volume":"36","author":"K Rasiya","year":"2021","unstructured":"Rasiya K, Sebastian D. Iturin and surfactin from the endophyte Bacillus amyloliquefaciens strain RKEA3 exhibits antagonism against Staphylococcus aureus. Biocatal Agric Biotechnol. 2021;36:102125.","journal-title":"Biocatal Agric Biotechnol"},{"key":"5464_CR28","doi-asserted-by":"publisher","first-page":"127256","DOI":"10.1016\/j.micres.2022.127256","volume":"266","author":"GD Kandasamy","year":"2023","unstructured":"Kandasamy GD, Kathirvel P. Insights into bacterial endophytic diversity and isolation with a focus on their potential applications\u2013A review. Microbiol Res. 2023;266:127256.","journal-title":"Microbiol Res"},{"key":"5464_CR29","doi-asserted-by":"publisher","first-page":"924","DOI":"10.3389\/fmicb.2018.00924","volume":"9","author":"OA Mohamad","year":"2018","unstructured":"Mohamad OA, Li L, Ma J-B, Hatab S, Xu L, Guo J-W, et al. Evaluation of the antimicrobial activity of endophytic bacterial populations from Chinese traditional medicinal plant licorice and characterization of the bioactive secondary metabolites produced by Bacillus atrophaeus against Verticillium dahliae. Front Microbiol. 2018;9:924.","journal-title":"Front Microbiol"},{"key":"5464_CR30","doi-asserted-by":"publisher","unstructured":"Ameri R, Shahraki SS. Evaluation of Antifungal Effect of Allium jesdianum Bacterial Endophytes on Rhizopus stolonifer, Penicillium, Cladosporium, and Trichophyton mentagrophytes. J Microbiota. 2024;1(1):e144397. https:\/\/doi.org\/10.5812\/jmb-144397.","DOI":"10.5812\/jmb-144397"},{"issue":"2","key":"5464_CR31","doi-asserted-by":"publisher","first-page":"199","DOI":"10.15408\/jkv.v8i2.25686","volume":"8","author":"I Asy\u2019ari","year":"2022","unstructured":"Asy\u2019ari I, Ngadiwiyana NBAP. Antibacterial and Antioxidant Activity of Endophytic Bacteria Isolated from Hibiscus tilaceus Leaves. Jurnal Kimia Valensi. 2022;8(2):199\u2013210.","journal-title":"Jurnal Kimia Valensi"},{"issue":"10","key":"5464_CR32","doi-asserted-by":"publisher","first-page":"2480","DOI":"10.3390\/microorganisms11102480","volume":"11","author":"DS Basavarajappa","year":"2023","unstructured":"Basavarajappa DS, Niazi SK, Bepari A, Assiri RA, Hussain SA, Muzaheed, et al. Efficacy of Penicillium limosum Strain AK-7 Derived Bioactive Metabolites on Antimicrobial, Antioxidant, and Anticancer Activity against Human Ovarian Teratocarcinoma (PA-1) Cell Line. Microorganisms [Internet]. 2023;11(10):2480.","journal-title":"Microorganisms [Internet]"},{"issue":"6","key":"5464_CR33","first-page":"348","volume":"72","author":"GH Park","year":"2017","unstructured":"Park GH, Song HM, Kim YS, Jeon Y, Koo JS, Jeong HJ, et al. Anti-cancer activity of Bacillus amyloliquefaciens AK-0 through cyclin D1 proteasomal degradation via GSK3\u03b2-dependent phosphorylation of threonine-286. Die Pharmazie-An Int J Pharm Sci. 2017;72(6):348\u201354.","journal-title":"Die Pharmazie-An Int J Pharm Sci"},{"issue":"10","key":"5464_CR34","doi-asserted-by":"publisher","first-page":"972","DOI":"10.3390\/antibiotics13100972","volume":"13","author":"S Ravaioli","year":"2024","unstructured":"Ravaioli S, De Donno A, Bottau G, Campoccia D, Maso A, Dolzani P, et al. The Opportunistic Pathogen Staphylococcus warneri: Virulence and Antibiotic Resistance, Clinical Features, Association with Orthopedic Implants and Other Medical Devices, and a Glance at Industrial Applications. Antibiotics. 2024;13(10):972.","journal-title":"Antibiotics"},{"key":"5464_CR35","doi-asserted-by":"publisher","unstructured":"Sunkar S, Nachiyar CV, Sethia S, Ghosh B, Prakash P, Devi KR. Biosurfactant from endophytic Bacillus cereus: Optimization, characterization and cytotoxicity study. Malaysian J Microbiol. 2019;15(2). https:\/\/doi.org\/10.21161\/MJM.180061.","DOI":"10.21161\/MJM.180061"},{"issue":"7","key":"5464_CR36","first-page":"135","volume":"2","author":"K Sayali","year":"2013","unstructured":"Sayali K, Sadichha P, Surekha S. Microbial esterases: an overview. Int J Curr Microbiol Appl Sci. 2013;2(7):135\u201346.","journal-title":"Int J Curr Microbiol Appl Sci"},{"key":"5464_CR37","unstructured":"Shoge M. Antimicrobial activity of 1, 2 butyldecyl ester isolated from Acacia niloti. 2014."},{"key":"5464_CR38","doi-asserted-by":"publisher","first-page":"542891","DOI":"10.3389\/fphar.2021.542891","volume":"12","author":"S Taritla","year":"2021","unstructured":"Taritla S, Kumari M, Kamat S, Bhat SG, Jayabaskaran C. Optimization of PhysicoChemical Parameters for Production of Cytotoxic Secondary Metabolites and Apoptosis Induction Activities in the Culture Extract of a Marine Algal\u2013Derived Endophytic Fungus Aspergillus sp. Front Pharmacol. 2021;12:542891.","journal-title":"Front Pharmacol"},{"key":"5464_CR39","doi-asserted-by":"publisher","first-page":"112514","DOI":"10.1016\/j.biopha.2021.112514","volume":"146","author":"M Sharma","year":"2022","unstructured":"Sharma M, Grewal K, Jandrotia R, Batish DR, Singh HP, Kohli RK. Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement. Biomed Pharmacother. 2022;146:112514.","journal-title":"Biomed Pharmacother"},{"key":"5464_CR40","doi-asserted-by":"publisher","first-page":"879386","DOI":"10.3389\/fmicb.2022.879386","volume":"13","author":"M Sharma","year":"2022","unstructured":"Sharma M, Mallubhotla S. Diversity, antimicrobial activity, and antibiotic susceptibility pattern of endophytic bacteria sourced from Cordia dichotoma L. Front Microbiol. 2022;13:879386.","journal-title":"Front Microbiol"},{"key":"5464_CR41","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1134\/S0003683820060083","volume":"56","author":"M Kuyukina","year":"2020","unstructured":"Kuyukina M, Varushkina A, Ivshina I. Effects of electroporation on antibiotic susceptibility and adhesive activity to n-hexadecane in Rhodococcus ruber IEGM 231. Appl Biochem Microbiol. 2020;56:729\u201335.","journal-title":"Appl Biochem Microbiol"},{"issue":"1","key":"5464_CR42","first-page":"497606","volume":"2014","author":"F Mujeeb","year":"2014","unstructured":"Mujeeb F, Bajpai P, Pathak N. Phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of Aegle marmelos. Biomed Res Int. 2014;2014(1):497606.","journal-title":"Biomed Res Int"},{"key":"5464_CR43","doi-asserted-by":"publisher","first-page":"1239658","DOI":"10.3389\/fphar.2023.1239658","volume":"14","author":"S Poyraz","year":"2023","unstructured":"Poyraz S, D\u00f6nda\u015f HA, D\u00f6nda\u015f NY, Sansano JM. Recent insights about pyrrolidine core skeletons in pharmacology. Front Pharmacol. 2023;14:1239658.","journal-title":"Front Pharmacol"},{"key":"5464_CR44","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1134\/S0026261718060152","volume":"88","author":"I Solyanikova","year":"2019","unstructured":"Solyanikova I, Golovleva L. Hexadecane and hexadecane-degrading bacteria: mechanisms of interaction. Microbiology. 2019;88:15\u201326.","journal-title":"Microbiology"},{"key":"5464_CR45","doi-asserted-by":"publisher","unstructured":"Subramanian S, Dowlath MJH, Karuppannan SK, Arunachalam KD. Effect of solvent on the phytochemical extraction and GC-MS analysis of Gymnema sylvestre. Pharmacognosy J. 2020;12(4). https:\/\/doi.org\/10.5530\/pj.2020.12.108.","DOI":"10.5530\/pj.2020.12.108"},{"issue":"1","key":"5464_CR46","doi-asserted-by":"publisher","first-page":"9","DOI":"10.31788\/RJC.2023.1618051","volume":"16","author":"N Andalia","year":"2023","unstructured":"Andalia N, Salim MN, Saidi N, Ridhwan M, Balqis U. Qualitative secondary metabolite and FT-IR profiles of the methanolic extract from Muntingia calabura L. leaves. Rasayan J Chem. 2023;16(1):9\u201313.","journal-title":"Rasayan J Chem"},{"key":"5464_CR47","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.antiviral.2017.06.014","volume":"144","author":"E Lomonosova","year":"2017","unstructured":"Lomonosova E, Daw J, Garimallaprabhakaran AK, Agyemang NB, Ashani Y, Murelli RP, et al. Efficacy and cytotoxicity in cell culture of novel \u03b1-hydroxytropolone inhibitors of hepatitis B virus ribonuclease H. Antiviral Res. 2017;144:164\u201372.","journal-title":"Antiviral Res"},{"issue":"5","key":"5464_CR48","doi-asserted-by":"publisher","first-page":"3733","DOI":"10.3390\/cimb45050241","volume":"45","author":"SK Niazi","year":"2023","unstructured":"Niazi SK, Basavarajappa DS, Kumaraswamy SH, Bepari A, Hiremath H, Nagaraja SK, et al. GC-MS Based Characterization, Antibacterial, Antifungal and Anti-Oncogenic Activity of Ethyl Acetate Extract of Aspergillus niger Strain AK-6 Isolated from Rhizospheric Soil. Curr Issues Mol Biology [Internet]. 2023;45(5):3733\u201356. pp.].","journal-title":"Curr Issues Mol Biology [Internet]"}],"container-title":["BMC Complementary Medicine and Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12906-026-05464-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-026-05464-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12906-026-05464-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:46:33Z","timestamp":1791668793000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12906-026-05464-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5464"],"URL":"https:\/\/doi.org\/10.1186\/s12906-026-05464-6","relation":{},"ISSN":["2662-7671"],"issn-type":[{"value":"2662-7671","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]},"assertion":[{"value":"30 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the Ethics Committee of Isfahan University of Medical Sciences, Isfahan, Iran (Approval No. IR.MUI.MED.REC.1400.653). All experimental procedures were conducted in accordance with the relevant institutional guidelines and regulations.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"293"}}