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The aim was to determine numbers and causes of NSIs as well as the frequency with which medical students report NSIs in the final stages of study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An online questionnaire was developed and made available in January and February 2023 to all undergraduate medical students (<jats:italic>n<\/jats:italic>\u2009=\u2009423) in the last 1.5\u2009years of their degree course at W\u00fcrzburg University, Germany.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The response rate was 19.6% (<jats:italic>n<\/jats:italic>\u2009=\u200984). Among respondents, 27.4% (<jats:italic>n<\/jats:italic>\u2009=\u200923) reported at least one NSI. Occurrence was particularly frequent in surgery, obstetrics and gynaecology, and internal medicine. Assisting with procedures, suturing, and blood sampling were considered high-risk activities. Lack of concentration, distraction, and time pressure played a role in incidents. Respondents did not report 18.8% of NSIs with the main reasons being fear of the consequences, self-assessment of the injury as minor, or the opinion of supervisors that reporting was unnecessary. Students with previous practice on simulators or patients were significantly more likely to suffer NSIs. Instructions from occupational health specialists beforehand correlated with fewer NSIs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We assume that trained students are more experienced in handling invasive procedures, leading to a greater adoption of corresponding activities and thus an increased risk of injuries in absolute numbers. This does not counter the need for didactic interventions prior to workplace-based training to raise awareness of NSI risks. Simultaneously, concepts must be developed and implemented to support reporting and alleviate fears regarding consequences.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12909-024-05309-1","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T11:02:03Z","timestamp":1710932523000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Combatting the occurrence of needle-stick injuries in a medical school: why is it still an issue?"],"prefix":"10.1186","volume":"24","author":[{"given":"Franca","family":"Keicher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janina","family":"Zirkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Leutritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"K\u00f6nig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,20]]},"reference":[{"issue":"1","key":"5309_CR1","first-page":"22","volume":"17","author":"S Siegmann","year":"2016","unstructured":"Siegmann S, Muth T, Kluth W, Hofbauer U, Angerer P, Schwarze S. 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