{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T23:03:46Z","timestamp":1784156626855,"version":"3.55.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T00:00:00Z","timestamp":1732579200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T00:00:00Z","timestamp":1732579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Research Foundation of Tri-Service General Hospital","award":["TSGH_D_113123"],"award-info":[{"award-number":["TSGH_D_113123"]}]},{"name":"Ministry of National Defense-Medical Affairs Bureau, Taiwan","award":["MND-MAB-D-114115"],"award-info":[{"award-number":["MND-MAB-D-114115"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Educ"],"DOI":"10.1186\/s12909-024-06333-x","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T00:51:20Z","timestamp":1732582280000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Simulated spinal durotomy repair for orthopaedic resident training: a perfusion-based porcine cadaveric specimen as an in vitro animal model"],"prefix":"10.1186","volume":"24","author":[{"given":"Chiu\u2011Ming","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Huang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0866-4149","authenticated-orcid":false,"given":"Jui-Jung","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,26]]},"reference":[{"key":"6333_CR1","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.injury.2010.12.014","volume":"43","author":"P Guerin","year":"2012","unstructured":"Guerin P, El Fegoun AB, Obeid I, Gille O, Lelong L, Luc S, et al. Incidental durotomy during spine surgery: incidence, management and complications. A retrospective review Injury. 2012;43:397\u2013401. https:\/\/doi.org\/10.1016\/j.injury.2010.12.014.","journal-title":"A retrospective review Injury"},{"key":"6333_CR2","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.jocn.2018.01.008","volume":"50","author":"M Galarza","year":"2018","unstructured":"Galarza M, Gazzeri R, Alfaro R, de la Rosa P, Arraez C, Piqueras C. Evaluation and management of small dural tears in primary lumbar spinal decompression and discectomy surgery. J Clin Neurosci. 2018;50:177\u201382. https:\/\/doi.org\/10.1016\/j.jocn.2018.01.008.","journal-title":"J Clin Neurosci"},{"key":"6333_CR3","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1007\/s00586-015-3837-x","volume":"24","author":"L Papavero","year":"2015","unstructured":"Papavero L, Engler N, Kothe R. Incidental durotomy in spine surgery: first aid in ten steps. Eur Spine J. 2015;24:2077\u201384. https:\/\/doi.org\/10.1007\/s00586-015-3837-x.","journal-title":"Eur Spine J"},{"key":"6333_CR4","doi-asserted-by":"publisher","unstructured":"Bosacco SJ, Gardner MJ, Guille JT. Evaluation and treatment of dural tears in lumbar spine surgery: a review. Clin Orthop Relat Res 2001:238\u201347. https:\/\/doi.org\/10.1097\/00003086-200108000-00033.","DOI":"10.1097\/00003086-200108000-00033"},{"key":"6333_CR5","doi-asserted-by":"publisher","first-page":"2275","DOI":"10.2106\/00004623-200710000-00025","volume":"89","author":"RM Zimmerman","year":"2007","unstructured":"Zimmerman RM, Kebaish KM. Intracranial hemorrhage following incidental durotomy during spinal surgery A report of four patients. J Bone Joint Surg Am. 2007;89:2275\u20139. https:\/\/doi.org\/10.2106\/00004623-200710000-00025.","journal-title":"J Bone Joint Surg Am"},{"key":"6333_CR6","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1097\/00024720-200404000-00007","volume":"17","author":"DJ deFreitas","year":"2004","unstructured":"deFreitas DJ, McCabe JP. Acinetobacter baumanii meningitis: a rare complication of incidental durotomy. J Spinal Disord Tech. 2004;17:115\u20136. https:\/\/doi.org\/10.1097\/00024720-200404000-00007.","journal-title":"J Spinal Disord Tech"},{"key":"6333_CR7","doi-asserted-by":"publisher","first-page":"400","DOI":"10.5435\/JAAOS-D-21-00756","volume":"30","author":"Z Wang","year":"2022","unstructured":"Wang Z, Shen J. Simulation training in spine surgery. J Am Acad Orthop Surg. 2022;30:400\u20138. https:\/\/doi.org\/10.5435\/JAAOS-D-21-00756.","journal-title":"J Am Acad Orthop Surg"},{"key":"6333_CR8","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1016\/j.spinee.2019.07.006","volume":"19","author":"K Phan","year":"2019","unstructured":"Phan K, Phan P, Stratton A, Kingwell S, Hoda M, Wai E. Impact of resident involvement on cervical and lumbar spine surgery outcomes. Spine J. 2019;19:1905\u201310. https:\/\/doi.org\/10.1016\/j.spinee.2019.07.006.","journal-title":"Spine J"},{"key":"6333_CR9","doi-asserted-by":"publisher","unstructured":"Baisiwala S, Shlobin NA, Cloney MB, Dahdaleh NS. Impact of Resident Participation During Surgery on Neurosurgical Outcomes: A Meta-Analysis. World Neurosurg 2020;142:1\u201312. https:\/\/doi.org\/10.1016\/j.wneu.2020.05.266.","DOI":"10.1016\/j.wneu.2020.05.266"},{"key":"6333_CR10","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3171\/2020.6.SPINE20795","volume":"174","author":"GJ Farah","year":"2023","unstructured":"Farah GJ, Rogers JL, Lopez AM, Brown NJ, Pennington Z, Kuo C, et al. Resident training in spine surgery: a systematic review of simulation-based educational models. World Neurosurg. 2023;174:81\u2013115. https:\/\/doi.org\/10.3171\/2020.6.SPINE20795.","journal-title":"World Neurosurg"},{"key":"6333_CR11","doi-asserted-by":"publisher","first-page":"12","DOI":"10.20529\/IJME.2004.010","volume":"2","author":"M Ghasemi","year":"2009","unstructured":"Ghasemi M, Dehpour AR. Ethical considerations in animal studies. J Med Ethics Hist Med. 2009;2:12. https:\/\/doi.org\/10.20529\/IJME.2004.010.","journal-title":"J Med Ethics Hist Med"},{"key":"6333_CR12","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.3171\/2014.10.JNS1497","volume":"123","author":"JL Winer","year":"2015","unstructured":"Winer JL, Kramer DR, Robison RA, Ohiorhenuan I, Minneti M, Giannotta S, et al. Cerebrospinal fluid reconstitution via a perfusion-based cadaveric model: feasibility study demonstrating surgical simulation of neuroendoscopic procedures. J Neurosurg. 2015;123:1316\u201321. https:\/\/doi.org\/10.3171\/2014.10.JNS1497.","journal-title":"J Neurosurg"},{"key":"6333_CR13","doi-asserted-by":"publisher","first-page":"792","DOI":"10.3171\/2017.5.JNS162982","volume":"129","author":"EA Christian","year":"2018","unstructured":"Christian EA, Bakhsheshian J, Strickland BA, Fredrickson VL, Buchanan IA, Pham MH, et al. Perfusion-based human cadaveric specimen as a simulation training model in repairing cerebrospinal fluid leaks during endoscopic endonasal skull base surgery. J Neurosurg. 2018;129:792\u20136. https:\/\/doi.org\/10.3171\/2017.5.JNS162982.","journal-title":"J Neurosurg"},{"key":"6333_CR14","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1093\/ons\/opz111","volume":"17","author":"IA Buchanan","year":"2019","unstructured":"Buchanan IA, Min E, Pham MH, Donoho DA, Bakhsheshian J, Minneti M, et al. Simulation of dural repair in minimally invasive spine surgery with the use of a perfusion-based cadaveric model. Oper Neurosurg (Hagerstown). 2019;17:616\u201321. https:\/\/doi.org\/10.1093\/ons\/opz111.","journal-title":"Oper Neurosurg (Hagerstown)"},{"key":"6333_CR15","doi-asserted-by":"publisher","first-page":"8","DOI":"10.5603\/PJNNS.a2019.0001","volume":"53","author":"CO Morosanu","year":"2019","unstructured":"Morosanu CO, Nicolae L, Moldovan R, Farcasanu AS, Filip GA, Florian IS. Neurosurgical cadaveric and in vivo large animal training models for cranial and spinal approaches and techniques - a systematic review of the current literature. Neurol Neurochir Pol. 2019;53:8\u201317. https:\/\/doi.org\/10.5603\/PJNNS.a2019.0001.","journal-title":"Neurol Neurochir Pol"},{"key":"6333_CR16","doi-asserted-by":"publisher","first-page":"1859","DOI":"10.1007\/s00586-011-1822-6","volume":"20","author":"HJ Wilke","year":"2011","unstructured":"Wilke HJ, Geppert J, Kienle A. Biomechanical in vitro evaluation of the complete porcine spine in comparison with data of the human spine. Eur Spine J. 2011;20:1859\u201368. https:\/\/doi.org\/10.1007\/s00586-011-1822-6.","journal-title":"Eur Spine J"},{"key":"6333_CR17","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1093\/ons\/opy030","volume":"15","author":"Y Hou","year":"2018","unstructured":"Hou Y, Lin Y, Shi J, Chen H, Yuan W. Effectiveness of the thoracic pedicle screw placement using the virtual surgical training system: a cadaver study. Oper Neurosurg (Hagerstown). 2018;15:677\u201385. https:\/\/doi.org\/10.1093\/ons\/opy030.","journal-title":"Oper Neurosurg (Hagerstown)"},{"key":"6333_CR18","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1067\/mva.2001.114214","volume":"33","author":"HE Garrett Jr","year":"2001","unstructured":"Garrett HE Jr. A human cadaveric circulation model. J Vasc Surg. 2001;33:1128\u201330. https:\/\/doi.org\/10.1067\/mva.2001.114214.","journal-title":"J Vasc Surg"},{"issue":"Suppl 1B","key":"6333_CR19","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1177\/026119290403201s80","volume":"32","author":"E Aboud","year":"2004","unstructured":"Aboud E, Suarez CE, Al-Mefty O, Yasargil MG. New alternative to animal models for surgical training. Altern Lab Anim. 2004;32(Suppl 1B):501\u20137. https:\/\/doi.org\/10.1177\/026119290403201s80.","journal-title":"Altern Lab Anim"},{"key":"6333_CR20","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.3171\/2009.3.JNS081653","volume":"111","author":"RS Tubbs","year":"2009","unstructured":"Tubbs RS, Loukas M, Shoja MM, Wellons JC, Cohen-Gadol AA. Feasibility of ventricular expansion postmortem: a novel laboratory model for neurosurgical training that simulates intraventricular endoscopic surgery. J Neurosurg. 2009;111:1165\u20137. https:\/\/doi.org\/10.3171\/2009.3.JNS081653.","journal-title":"J Neurosurg"},{"key":"6333_CR21","doi-asserted-by":"publisher","unstructured":"Faulkner ND, Finn MA, Anderson PA. Hydrostatic comparison of nonpenetrating titanium clips versus conventional suture for repair of spinal durotomies. Spine (Phila Pa 1976) 2012;37:E535\u20139. https:\/\/doi.org\/10.1097\/BRS.0b013e31824cf756.","DOI":"10.1097\/BRS.0b013e31824cf756"},{"key":"6333_CR22","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1016\/j.spinee.2013.06.044","volume":"15","author":"EE Dafford","year":"2015","unstructured":"Dafford EE, Anderson PA. Comparison of dural repair techniques. Spine J. 2015;15:1099\u2013105. https:\/\/doi.org\/10.1016\/j.spinee.2013.06.044.","journal-title":"Spine J"},{"key":"6333_CR23","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1016\/j.spinee.2017.04.007","volume":"17","author":"J Bakhsheshian","year":"2017","unstructured":"Bakhsheshian J, Strickland BA, Patel NN, Jakoi AM, Minneti M, Zada G, et al. The use of a novel perfusion-based cadaveric simulation model with cerebrospinal fluid reconstitution comparing dural repair techniques: a pilot study. Spine J. 2017;17:1335\u201341. https:\/\/doi.org\/10.1016\/j.spinee.2017.04.007.","journal-title":"Spine J"},{"key":"6333_CR24","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1007\/s00586-010-1326-9","volume":"19","author":"I Busscher","year":"2010","unstructured":"Busscher I, Ploegmakers JJ, Verkerke GJ, Veldhuizen AG. Comparative anatomical dimensions of the complete human and porcine spine. Eur Spine J. 2010;19:1104\u201314. https:\/\/doi.org\/10.1007\/s00586-010-1326-9.","journal-title":"Eur Spine J"},{"issue":"Suppl 1","key":"6333_CR25","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1227\/NEU.0000000000000091","volume":"73","author":"GM Ghobrial","year":"2013","unstructured":"Ghobrial GM, Anderson PA, Chitale R, Campbell PG, Lobel DA, Harrop J. Simulated spinal cerebrospinal fluid leak repair: an educational model with didactic and technical components. Neurosurgery. 2013;73(Suppl 1):111\u20135. https:\/\/doi.org\/10.1227\/NEU.0000000000000091.","journal-title":"Neurosurgery"},{"key":"6333_CR26","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1227\/00006123-198802000-00021","volume":"22","author":"MN Hadley","year":"1988","unstructured":"Hadley MN, Martin NA, Spetzler RF, Sonntag VK, Johnson PC. Comparative transoral dural closure techniques: a canine model. Neurosurgery. 1988;22:392\u20137. https:\/\/doi.org\/10.1227\/00006123-198802000-00021.","journal-title":"Neurosurgery"},{"key":"6333_CR27","doi-asserted-by":"publisher","unstructured":"Cain JE, Jr., Rosenthal HG, Broom MJ, Jauch EC, Borek DA, Jacobs RR. Quantification of leakage pressures after durotomy repairs in the canine. Spine (Phila Pa 1976) 1990;15:969\u201370. https:\/\/doi.org\/10.1097\/00007632-199009000-00024.","DOI":"10.1097\/00007632-199009000-00024"},{"key":"6333_CR28","doi-asserted-by":"publisher","first-page":"642972","DOI":"10.3389\/fsurg.2021.642972","volume":"8","author":"K Shenoy","year":"2021","unstructured":"Shenoy K, Donnally CJ 3rd, Sheha ED, Khanna K, Prasad SK. An Investigation of a Novel Dural Repair Device for Intraoperative Incidental Durotomy Repair. Front Surg. 2021;8:642972. https:\/\/doi.org\/10.3389\/fsurg.2021.642972.","journal-title":"Front Surg"},{"key":"6333_CR29","doi-asserted-by":"publisher","unstructured":"Ye J, Hong Z, Chu B, Wang Z, Jiang L, Zhu Z, et al. Comparison of dural closure methods for dural repair to reduce the incidence of cerebrospinal fluid leakage. Br J Neurosurg 2021:1\u20136. https:\/\/doi.org\/10.1080\/02688697.2021.1950626.","DOI":"10.1080\/02688697.2021.1950626"}],"container-title":["BMC Medical Education"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12909-024-06333-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12909-024-06333-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12909-024-06333-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T01:02:34Z","timestamp":1732582954000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmededuc.biomedcentral.com\/articles\/10.1186\/s12909-024-06333-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,26]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["6333"],"URL":"https:\/\/doi.org\/10.1186\/s12909-024-06333-x","relation":{},"ISSN":["1472-6920"],"issn-type":[{"value":"1472-6920","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,26]]},"assertion":[{"value":"2 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethics approval for this study was waived by the Institutional Review Board of Tri-Service General Hospital (TSGHIRB) because the experiment involved the use of in vitro tissue purchased from a butcher and did not involve animals raised specifically for research purposes. Additionally, the participation of orthopedic residents did not require ethics approval, as the study posed no more than minimal risk to all participants. Informed written consent was obtained from all participants prior to the commencement of the study. The study was conducted in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1361"}}