{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T09:28:02Z","timestamp":1793266082617,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Med Inform Decis Mak"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12911-017-0479-4","type":"journal-article","created":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T07:42:31Z","timestamp":1498635751000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A Bayesian network and heuristic approach for systematic characterization of radiotherapy receipt after breast-conservation surgery"],"prefix":"10.1186","volume":"17","author":[{"given":"Milton","family":"Soto-Ferrari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0255-968X","authenticated-orcid":false,"given":"Diana","family":"Prieto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gitonga","family":"Munene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,28]]},"reference":[{"issue":"1","key":"479_CR1","first-page":"7","volume":"66","author":"RL Siegel","year":"2016","unstructured":"Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA: Cancer J Clin. 2016; 66(1):7\u201330.","journal-title":"CA: Cancer J Clin"},{"key":"479_CR2","unstructured":"National Comprehensive Cancer Network: NCCN Clinical Practice Guidelines in Oncology Breast Cancer Version 1. 2016. \n                        www.nccn.org\n                        \n                    . Accessed 01 June 2016."},{"issue":"9804","key":"479_CR3","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/S0140-6736(11)61629-2","volume":"378","author":"Early Breast Cancer Trialists\u2019 Collaborative Group","year":"2011","unstructured":"Early Breast Cancer Trialists\u2019 Collaborative Group, et al.Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials. Lancet. 2011; 378(9804):1707\u201316.","journal-title":"Lancet"},{"issue":"8","key":"479_CR4","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1200\/JCO.2013.50.6600","volume":"32","author":"\u00c5 Wickberg","year":"2014","unstructured":"Wickberg \u00c5, Holmberg L, Adami HO, Magnuson A, Villman K, Liljegren G. Sector resection with or without postoperative radiotherapy for stage I breast cancer: 20-year results of a randomized trial. J Clin Oncol. 2014; 32(8):791\u20137.","journal-title":"J Clin Oncol"},{"issue":"13","key":"479_CR5","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1200\/JCO.2005.04.028","volume":"23","author":"SJ Katz","year":"2005","unstructured":"Katz SJ, Lantz PM, Janz NK, Fagerlin A, Schwartz K, Liu L, Deapen D, Salem B, Lakhani I, Morrow M. Patterns and correlates of local therapy for women with ductal carcinoma-in-situ. J Clin Oncol. 2005; 23(13):3001\u20137.","journal-title":"J Clin Oncol"},{"issue":"2","key":"479_CR6","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1245\/s10434-010-1335-2","volume":"18","author":"L Kelley","year":"2011","unstructured":"Kelley L, Silverstein M, Guerra L. Analyzing the risk of recurrence after mastectomy for DCIS: a new use for the USC\/Van Nuys Prognostic Index. Ann Surg Oncol. 2011; 18(2):459\u201362.","journal-title":"Ann Surg Oncol"},{"issue":"10","key":"479_CR7","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1002\/cncr.26559","volume":"118","author":"LL Lipscombe","year":"2012","unstructured":"Lipscombe LL, Fischer HD, Yun L, Gruneir A, Austin P, Paszat L, Anderson GM, Rochon PA. Association between tamoxifen treatment and diabetes. Cancer. 2012; 118(10):2615\u201322.","journal-title":"Cancer"},{"issue":"6","key":"479_CR8","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1053\/j.seminoncol.2003.08.028","volume":"30","author":"B Ramaswamy","year":"2003","unstructured":"Ramaswamy B, Shapiro CL. Osteopenia and osteoporosis in women with breast cancer. Semin Oncol. 2003; 30(6):763\u201375.","journal-title":"Semin Oncol"},{"issue":"1","key":"479_CR9","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/cncr.23513","volume":"113","author":"TP Srokowski","year":"2008","unstructured":"Srokowski TP, Fang S, Duan Z, Buchholz TA, Hortobagyi GN, Goodwin JS, Giordano SH. Completion of adjuvant radiation therapy among women with breast cancer. Cancer. 2008; 113(1):22\u20139.","journal-title":"Cancer"},{"issue":"28","key":"479_CR10","doi-asserted-by":"crossref","first-page":"7074","DOI":"10.1200\/JCO.2005.06.032","volume":"23","author":"AT Schroen","year":"2005","unstructured":"Schroen AT, Brenin DR, Kelly MD, Knaus WA, Slingluff CL. Impact of patient distance to radiation therapy on mastectomy use in early-stage breast cancer patients. J Clin Oncol. 2005; 23(28):7074\u201380.","journal-title":"J Clin Oncol"},{"key":"479_CR11","unstructured":"National Comprehensive Cancer Network: NCCN Clinical Practice Guidelines in Oncology Older Adult Oncology Version 1.2016. \n                        www.nccn.org\n                        \n                    . Accessed 01 July 16."},{"issue":"3","key":"479_CR12","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.critrevonc.2010.05.010","volume":"79","author":"BL Van Leeuwen","year":"2011","unstructured":"Van Leeuwen BL, Rosenkranz K, Feng LL, Bedrosian I, Hartmann K, Hunt K, Kuerer H, Ross M, Singletary S, Babiera GV, et al. The effect of under-treatment of breast cancer in women 80 years of age and older. Crit Rev Oncol Hematol. 2011; 79(3):315\u201320.","journal-title":"Crit Rev Oncol Hematol"},{"issue":"3","key":"479_CR13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/01.coc.0000156922.58631.d7","volume":"28","author":"I Jatoi","year":"2005","unstructured":"Jatoi I, Proschan MA. Randomized trials of breast-conserving therapy versus mastectomy for primary breast cancer: a pooled analysis of updated results. Am J Clin Oncol. 2005; 28(3):289\u201394.","journal-title":"Am J Clin Oncol"},{"issue":"2","key":"479_CR14","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0167-8140(03)00002-1","volume":"67","author":"V Vinh-Hung","year":"2003","unstructured":"Vinh-Hung V, Voordeckers M, Van de Steene J, Soete G, Lamote J, Storme G. Omission of radiotherapy after breast-conserving surgery: survival impact and time trends. Radiother Oncol. 2003; 67(2):147\u201358.","journal-title":"Radiother Oncol"},{"issue":"5","key":"479_CR15","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1200\/JCO.2008.17.9234","volume":"27","author":"RA Freedman","year":"2009","unstructured":"Freedman RA, He Y, Winer EP, Keating NL. Trends in racial and age disparities in definitive local therapy of early-stage breast cancer. J Clin Oncol. 2009; 27(5):713\u20139.","journal-title":"J Clin Oncol"},{"issue":"6","key":"479_CR16","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1002\/cncr.25623","volume":"117","author":"SB Motwani","year":"2011","unstructured":"Motwani SB, Goyal S, Moran MS, Chhabra A, Haffty BG. Ductal carcinoma in situ treated with breast-conserving surgery and radiotherapy: A comparison with ECOG study 5194. Cancer. 2011; 117(6):1156\u201362.","journal-title":"Cancer"},{"issue":"7","key":"479_CR17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1093\/jnci\/djs142","volume":"104","author":"SY Wang","year":"2012","unstructured":"Wang SY, Chu H, Shamliyan T, Jalal H, Kuntz KM, Kane RL, Virnig BA. Network meta-analysis of margin threshold for women with ductal carcinoma in situ. J Nat Cancer Inst. 2012; 104(7):507\u201316.","journal-title":"J Nat Cancer Inst"},{"issue":"5","key":"479_CR18","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.amjsurg.2013.03.008","volume":"206","author":"DY Lee","year":"2013","unstructured":"Lee DY, Lewis JL, Wexelman BA, Freedman BC, Ross RE, Tartter PI. The consequence of undertreatment of patients treated with breast conserving therapy for ductal carcinoma in-situ. Am J Surg. 2013; 206(5):790\u20137.","journal-title":"Am J Surg"},{"issue":"3","key":"479_CR19","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF01840841","volume":"22","author":"PM Ravdin","year":"1992","unstructured":"Ravdin PM, Clark GM. A practical application of neural network analysis for predicting outcome of individual breast cancer patients. Breast Cancer Res Treat. 1992; 22(3):285\u201393.","journal-title":"Breast Cancer Res Treat"},{"issue":"4","key":"479_CR20","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1287\/opre.43.4.570","volume":"43","author":"OL Mangasarian","year":"1995","unstructured":"Mangasarian OL, Street WN, Wolberg WH. Breast cancer diagnosis and prognosis via linear programming. Oper Res. 1995; 43(4):570\u20137.","journal-title":"Oper Res"},{"issue":"1","key":"479_CR21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0933-3657(02)00086-6","volume":"27","author":"JM Jerez-Aragon\u00e9s","year":"2003","unstructured":"Jerez-Aragon\u00e9s JM, G\u00f3mez-Ruiz JA, Ramos-Jim\u00e9nez G, Mu\u00f1oz-P\u00e9rez J, Alba-Conejo E. A combined neural network and decision trees model for prognosis of breast cancer relapse. Artif Intell Med. 2003; 27(1):45\u201363.","journal-title":"Artif Intell Med"},{"issue":"2","key":"479_CR22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.artmed.2004.07.002","volume":"34","author":"D Delen","year":"2005","unstructured":"Delen D, Walker G, Kadam A. Predicting breast cancer survivability: a comparison of three data mining methods. Artif Intell Med. 2005; 34(2):113\u201327.","journal-title":"Artif Intell Med"},{"issue":"1","key":"479_CR23","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0010-4825(96)00039-X","volume":"27","author":"CE Kahn","year":"1997","unstructured":"Kahn CE, Roberts LM, Shaffer KA, Haddawy P. Construction of a bayesian network for mammographic diagnosis of breast cancer. Comput Biol Med. 1997; 27(1):19\u201329.","journal-title":"Comput Biol Med"},{"issue":"1","key":"479_CR24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0933-3657(03)00033-2","volume":"28","author":"PJ Lisboa","year":"2003","unstructured":"Lisboa PJ, Wong H, Harris P, Swindell R. A bayesian neural network approach for modelling censored data with an application to prognosis after surgery for breast cancer. Artif Intell Med. 2003; 28(1):1\u201325.","journal-title":"Artif Intell Med"},{"issue":"14","key":"479_CR25","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/bioinformatics\/btl230","volume":"22","author":"O Gevaert","year":"2006","unstructured":"Gevaert O, De Smet F, Timmerman D, Moreau Y, De Moor B. Predicting the prognosis of breast cancer by integrating clinical and microarray data with bayesian networks. Bioinformatics. 2006; 22(14):184\u201390.","journal-title":"Bioinformatics"},{"issue":"21","key":"479_CR26","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1093\/bioinformatics\/btp505","volume":"25","author":"M Gerstung","year":"2009","unstructured":"Gerstung M, Baudis M, Moch H, Beerenwinkel N. Quantifying cancer progression with conjunctive bayesian networks. Bioinformatics. 2009; 25(21):2809\u201315.","journal-title":"Bioinformatics"},{"key":"479_CR27","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4614-6446-4","volume-title":"Bayesian Networks in R: with Applications in Systems Biology","author":"R Nagarajan","year":"2013","unstructured":"Nagarajan R, Scutari M, L\u00e8bre S. Bayesian Networks in R: with Applications in Systems Biology. New York: Springer-Verlag; 2013."},{"key":"479_CR28","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4614-2299-0","volume-title":"Graphical Models with R.","author":"S H\u00f8jsgaard","year":"2012","unstructured":"H\u00f8jsgaard S, Edwards D, Lauritzen S. Graphical Models with R.New York: Springer-Verlag; 2012."},{"issue":"4","key":"479_CR29","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.amjsurg.2008.06.017","volume":"196","author":"J Sariego","year":"2008","unstructured":"Sariego J. Regional variation in breast cancer treatment throughout the united states. Am J Surg. 2008; 196(4):572\u20134.","journal-title":"Am J Surg"},{"issue":"14","key":"479_CR30","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1016\/j.ejca.2006.03.019","volume":"42","author":"SR Lakhani","year":"2006","unstructured":"Lakhani SR, Audretsch W, Cleton-Jensen AM, Cutuli B, Ellis I, Eusebi V, Greco M, Houslton RS, Kuhl CK, Kurtz J, et al.The management of lobular carcinoma in situ (lcis). Is LCIS the same as ductal carcinoma in situ (DCIS)?Eur J Cancer. 2006; 42(14):2205\u201311.","journal-title":"Eur J Cancer"},{"issue":"6","key":"479_CR31","doi-asserted-by":"crossref","first-page":"923","DOI":"10.3109\/02841868909092333","volume":"28","author":"I Fentiman","year":"1989","unstructured":"Fentiman I. The treatment of in situ breast cancer. Acta Oncol. 1989; 28(6):923\u20136.","journal-title":"Acta Oncol"}],"container-title":["BMC Medical Informatics and Decision Making"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12911-017-0479-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T07:42:55Z","timestamp":1498635775000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcmedinformdecismak.biomedcentral.com\/articles\/10.1186\/s12911-017-0479-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,28]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["479"],"URL":"https:\/\/doi.org\/10.1186\/s12911-017-0479-4","relation":{},"ISSN":["1472-6947"],"issn-type":[{"value":"1472-6947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,28]]},"article-number":"93"}}