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However, there is limited evidence on applications that simultaneously support cancer patients through structured prevention and treatment guidance while enhancing healthcare workers\u2019 competencies. This study aimed to assess the outcomes of an AI-based mobile application as a supportive tool for cancer patients and examine its impact on healthcare workers\u2019 competence in routine oncology care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A quasi-experimental pre-post design was conducted with 60 cancer patients and 60 healthcare workers. The AI-based mobile application provided content on education, symptom management, and protocol-based support. Data was collected through structured online questionnaires before and after a 12-week intervention using five tools to assess usability, perceived benefits, efficiency of healthcare workers, health awareness, and selected chemotherapy-related symptoms. The same instruments were used for pre- and post-measurements without a control group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Post-intervention findings indicated improved patient-reported usability of the mobile application, with most participants reporting clarity and perceived usefulness, although some reported occasional confusion or irrelevant responses. Healthcare workers demonstrated statistically significant improvements in perceived efficiency and benefits related to application use (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). An increase in reported health awareness among nurses was observed. Patients also reported reductions in the severity of chemotherapy-related symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings suggest that the AI-based mobile application may serve as a supportive digital tool in oncology settings by assisting patients in following prevention and treatment guidance and supporting healthcare workers\u2019 perceived efficiency and awareness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial number<\/jats:title>\n                    <jats:p>Not applicable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12911-026-03432-1","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T19:14:06Z","timestamp":1774984446000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of artificial intelligence mobile app-guided prevention and treatment protocols on cancer patients and their impact on healthcare workers\u2019 competence"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3035-7073","authenticated-orcid":false,"given":"Eman A.","family":"Shokr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"3432_CR1","doi-asserted-by":"publisher","first-page":"113420","DOI":"10.1016\/j.socscimed.2020.113420","volume":"266","author":"M Hensher","year":"2020","unstructured":"Hensher M, Canny B, Zimitat C, Campbell J, Palmer A. 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Previous to data collection, informed consent was obtained from all participants. Completion of the questionnaire was considered as an indication of voluntary participation. All procedures followed in the study adhered to the ethical standards of the institutional research committee and were consistent with the principles of the Helsinki Declaration (2013). All methods were carried out in harmony with relevant guidelines and regulations. All patient data collected through the AI-based mobile application were anonymized and handled confidentially. Access to the application and stored data was restricted to the research team using secure, password-protected systems. Data were used solely for research purposes and stored in compliance with institutional ethical guidelines.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"165"}}