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Ten databases (Web of Science, PubMed, EMBASE, Cochrane Library, CINAHL, PsycInfo, China Biology Medicine, China National Knowledge Infrastructure, Wanfang Data, and China Science and Technology Journal Database) were searched for relevant studies published from the inception of the database to October 2023. Eight qualitative studies were analysed. The following seven themes were included: \u2018feeding pressure\u2019, \u2018hope for education\u2019, \u2018societal rejection and stigma\u2019, \u2018psychological pressure\u2019, \u2018caring burden\u2019, \u2018family burden\u2019, and \u2018family adaptation and self-growth\u2019.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>We found that feeding pressures, educational concerns, language difficulties, and discrimination and stigmatisation led to psychological, economic, and family stress in caregivers of children with Down syndrome. We document the need for strong coping mechanisms and support systems for these families from medical and psychological institutions and a need for public education and awareness.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>We summarised the daily care experiences of caregivers of children with Down syndrome. Our findings provide a scientific basis for further research focused on reducing physical and mental pressure on caregivers and improving the quality of family life.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s12912-024-02652-y","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T11:42:46Z","timestamp":1737373366000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Caregivers\u2019 experience of having a child with Down syndrome: a meta-synthesis"],"prefix":"10.1186","volume":"24","author":[{"given":"Xiao Nan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi Hong","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai Tao","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"issue":"12","key":"2652_CR1","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1038\/nrn3314","volume":"13","author":"M Dierssen","year":"2012","unstructured":"Dierssen M. 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