{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:36:07Z","timestamp":1787020567358,"version":"build-2736575974"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T00:00:00Z","timestamp":1631145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T00:00:00Z","timestamp":1631145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Health Serv Res"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Despite prioritization, routine antenatal influenza vaccine coverage is &lt;\u200916% in South Africa. We aimed to describe maternal influenza vaccine coverage in 27 antenatal clinics (ANCs) in Gauteng and Western Cape (WC) Provinces, where in collaboration with the Department of Health (DoH), we augmented the annual influenza vaccination programme among pregnant women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 2015 through 2018, 40,230 additional doses of influenza vaccine were added to the available stock and administered as part of routine antenatal care. Educational talks were given daily and data were collected on women attending ANCs. We compared characteristics of vaccinated and unvaccinated women using multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We screened 62,979 pregnant women during the period when Southern Hemisphere influenza vaccines were available (27,068 in Gauteng and 35,911 in WC). Vaccine coverage at the targeted clinics was 78.7% (49,355\/62682), although pregnant women in WC were more likely to be vaccinated compared to those in the Gauteng (Odds ratio (OR) =3.7\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Women aged 25\u201429 and\u2009&gt;\u200935\u2009years were less likely to be vaccinated than women aged 18\u201424\u2009years (OR\u2009=\u20090.9\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.053; OR\u2009=\u20090.9\n                      <jats:italic>p\u2009&lt;<\/jats:italic>\n                      \u00a00.001). HIV positive status was not associated with vaccination (OR\u2009=\u20091.0\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.266). Reasons for not vaccinating included: vaccine stock-outs where ANCs depleted available stock of vaccines and\/or were awaiting delivery of vaccines (54.6%, 6949\/12723), refusal\/indecision (25.8%, 3285), and current illness that contraindicated vaccination (19.6%, 2489).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Antenatal vaccination uptake was likely improved by the increased vaccine supply and vaccine education offered during our campaign.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12913-021-06962-8","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T02:02:48Z","timestamp":1631152968000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["An evaluation of an influenza vaccination campaign targeting pregnant women in 27 clinics in two provinces of South Africa, 2015 \u2013 2018"],"prefix":"10.1186","volume":"21","author":[{"given":"Kate","family":"Bishop","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith","family":"McMorrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Meiring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibongile","family":"Walaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liza","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarona","family":"Mhlanga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Tempia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azwifarwi","family":"Mathunjwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jackie","family":"Kleynhans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace D.","family":"Appiah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna M.","family":"McAnerney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather J.","family":"Zar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,9]]},"reference":[{"issue":"27","key":"6962_CR1","doi-asserted-by":"publisher","first-page":"4288","DOI":"10.1016\/j.vaccine.2020.04.045","volume":"38","author":"S Tempia","year":"2020","unstructured":"Tempia S, Walaza S, Moyes J, et al. 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The National Health Research Committee and the WC Provincial Health Research Committee also approved the protocol. Informed consent was not required to utilise data from vaccine registers, as these were collected as part of routine healthcare practice in collaboration with the DoH. Verbal informed consent was obtained from staff participating in the IPIE campaign evaluation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Cheryl Cohen has received grant support from Sanofi Pasteur, Advanced Vaccine Initiative, U.S. Centers for Disease Control and Prevention, and payment of travel costs from Parexel. The rest of the authors have no competing interests to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"941"}}