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We conducted a pre-post study from October 2019 to March 2020 to determine the effect of this strategy on HTN and HIV outcomes at baseline and six months. Our cohort comprised adult PLHIV diagnosed with HTN who made at least one clinic visit within two months prior to study onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>We enrolled 1,015 hypertensive PLHIV. The mean age was 50.1\u2009\u00b1\u20099.5\u00a0years and 62.6% were female. HTN outcomes improved between baseline and six months: mean systolic BP (154.3\u2009\u00b1\u200920.0 to 132.3\u2009\u00b1\u200913.8\u00a0mmHg,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001); mean diastolic BP (97.7\u2009\u00b1\u200913.1 to 85.3\u2009\u00b1\u20099.5\u00a0mmHg,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and proportion of patients with controlled HTN (9.3% to 74.1%,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The HTN care cascade also improved: treatment initiation (13.4% to 100%), retention in care (16.2% to 98.5%), monitoring (16.2% to 98.5%), and BP control among those initiated on HTN treatment (2.2% to 75.2%). HIV cascade steps remained high (&gt;\u200995% at baseline and six months) and viral suppression was unchanged (98.7% to 99.2%,<jats:italic>p<\/jats:italic>\u2009=\u20090.712). Taking ART for more than two years and HIV viral suppression were independent predictors of HTN control at six months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A HEARTS-based implementation strategy at a large, urban HIV center facilitates integration of HTN and HIV care and improves HTN outcomes while sustaining HIV control. Further implementation research is needed to study HTN\/HIV integration in varied clinical settings among diverse populations.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12913-022-08045-8","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T02:03:27Z","timestamp":1653444207000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Improved hypertension control at six months using an adapted WHO HEARTS-based implementation strategy at a large urban HIV clinic in Uganda"],"prefix":"10.1186","volume":"22","author":[{"given":"Martin","family":"Muddu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred C.","family":"Semitala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Kimera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Mbuliro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Ssennyonjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon P.","family":"Kigozi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodgers","family":"Katwesigye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Ayebare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christabellah","family":"Namugenyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Mugabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Mutungi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris T.","family":"Longenecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne R.","family":"Katahoire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Ssinabulya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy I.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,25]]},"reference":[{"key":"8045_CR1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.11604\/pamj.2019.33.87.15574","volume":"33","author":"PJ Pangmekeh","year":"2019","unstructured":"Pangmekeh PJ, Awolu MM, Gustave S, Gladys T, Cumber SNJTPAMJ. 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Pan Afr Med J. 2013;16:84.","journal-title":"Pan Afr Med J."}],"container-title":["BMC Health Services Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12913-022-08045-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12913-022-08045-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12913-022-08045-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T04:54:48Z","timestamp":1700628888000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmchealthservres.biomedcentral.com\/articles\/10.1186\/s12913-022-08045-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,25]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["8045"],"URL":"https:\/\/doi.org\/10.1186\/s12913-022-08045-8","relation":{},"ISSN":["1472-6963"],"issn-type":[{"value":"1472-6963","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,25]]},"assertion":[{"value":"20 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All participants provided verbal informed consent to participate in the study since they received integrated hypertension and HIV treatment as part of routine clinical care based on the WHO HEARTS guidelines. Additionally, the medications on our hypertension management protocol were already registered by the National Drug Authority for use in Uganda. The study protocol was approved by The AIDS Support Organization (TASO) Institutional Review Board (IRB) number TASOREC\/040\/19-UG-REC-009 and the Uganda National Council for Science and Technology (UNCST) number HS 2644.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no relevant competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"699"}}