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Despite growing research\u2014often focused on specific diseases\u2014 to date, no single review has comprehensively synthesized their definitions, causes, consequences, or methods of measurement. This scoping review addresses this gap by examining medical invalidation and related constructs.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Using a preregistered protocol, we systematically searched PubMed, CINAHL, Web of Science, Google Scholar, and ProQuest (dissertations) without year restrictions. Eligible sources included peer-reviewed empirical, theoretical, and conceptual work in English addressing invalidation, gaslighting, or closely related notions within healthcare. A total of 158 studies were identified through database searches and citation tracking. Data extraction followed a standardized schema, and findings were synthesized descriptively and through thematic analysis to clarify terminology, map determinants and outcomes, and identify existing measurement approaches.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The results showed substantial inconsistency in how \u201cinvalidation,\u201d \u201cnot being taken seriously,\u201d and \u201cgaslighting\u201d were defined. Medical invalidation emerged as a multifactorial phenomenon driven by diagnostic challenges, structural and societal factors, provider and patient characteristics, stigma, misattribution, interactional dynamics, academic knowledge gaps, and disease-related complexity. Invalidation was associated with wide-ranging behavioural, emotional, cognitive, physical, relational, and systemic harms, while validation had consistently beneficial effects. Proposed solutions in the summarized studies included communication improvements, clinician training, patient support, targeted research, and structural and systemic changes.<\/jats:p>\n <\/jats:sec>\n \n Discussions<\/jats:title>\n Medical invalidation represents a complex, systemic issue with significant implications for patient safety. The discussion highlights its multifactorial origins, its potential to cause both psychological and physical harm, and the need for clearer conceptualisation within the field. Advancing research requires validated instruments and longitudinal designs to examine underlying mechanisms and consequences. Addressing medical invalidation will demand multi-level interventions to improve communication, reduce structural barriers, and promote equitable, patient-centred care.<\/jats:p>\n <\/jats:sec>\n \n OSF Preregistration<\/jats:title>\n https:\/\/doi.org\/10.17605\/OSF.IO\/MPE6U<\/jats:p>\n <\/jats:sec>","DOI":"10.1186\/s12913-026-14736-3","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:05:24Z","timestamp":1788865524000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["What do we know about medical invalidation and related concepts? \u2013 A scoping review and thematic analysis about the definitions, measurements, causes, consequences and potential solutions for medical invalidation"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4439-5537","authenticated-orcid":false,"given":"Seraina Petra","family":"Lerch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Stille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"14736_CR1","unstructured":"Google. medical gaslighting \u2013 Google trends data (all regions, 2004\u2013present). 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