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The study protocol was approved by the Human Subjects Committee of Tianjin Women and Children\u2019s Health Center (the approval numbers are 2009\u201301, 2013\u201303-01, and 2017\u201303-01). All study participants provided written informed consent prior to their enrollment in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable. This manuscript does not contain any individual person\u2019s data in any form.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"97"}}