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This study examined whether being autistic affects diagnosis, symptoms, and health experiences of people with hypermobility, including hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD). We compare three groups: autistic adults, non-autistic adults, and adults who are not autistic but have a high level of autistic traits. Additionally, we examined which health and social factors predicted self-reported physical and mental health outcomes for autistic and non-autistic people with hEDS\/HSD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A total of 1754 participants completed an online questionnaire about their diagnostic experience, hypermobile symptoms, co-occurring health conditions, self-rated physical and mental health, engagement with health services, and employment and benefits status. Around 25% of respondents were autistic; a further 25% had high levels of autistic traits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Autistic participants had more symptoms of hEDS\/HSD and were more likely to have co-occurring physical and mental health conditions, compared with non-autistic and high autistic trait respondents. Autistic and high autistic trait participants self-reported poorer physical and mental health compared with non-autistic participants. Autistic participants\u2019 mental health was impacted by limitations to everyday activities, whereas non-autistic participants were more impacted by difficulties with self-care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Autistic and non-autistic people may experience hEDS\/HSD differently, which may impact the type of supports that are most beneficial to them.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12916-026-04713-2","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T03:34:21Z","timestamp":1771990461000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Health experiences and outcomes of autistic and non-autistic adults with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorder"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5280-1596","authenticated-orcid":false,"given":"Catherine J.","family":"Crompton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8458-5493","authenticated-orcid":false,"given":"Themis N.","family":"Efthimiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4656-6205","authenticated-orcid":false,"given":"Dervil M.","family":"Dockrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5972-4009","authenticated-orcid":false,"given":"Kathryn M.","family":"Berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"4713_CR1","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2013","unstructured":"American Psychiatric Association. 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