{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:34:43Z","timestamp":1787625283167,"version":"build-2736575974"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100002848","name":"Comisi\u00f3n Nacional de Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["21110863"],"award-info":[{"award-number":["21110863"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002848","name":"Comisi\u00f3n Nacional de Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["Doctorado Nacional"],"award-info":[{"award-number":["Doctorado Nacional"]}],"id":[{"id":"10.13039\/501100002848","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Vet Res"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12917-017-1053-0","type":"journal-article","created":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T11:45:39Z","timestamp":1496922339000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Omental adipose tissue is a more suitable source of canine Mesenchymal stem cells"],"prefix":"10.1186","volume":"13","author":[{"given":"Francisca","family":"Bahamondes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estefania","family":"Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gino","family":"Cattaneo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Bruna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulette","family":"Conget","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,8]]},"reference":[{"key":"1053_CR1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","volume":"8","author":"M Dominici","year":"2006","unstructured":"Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop DJ, Horwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315\u20137.","journal-title":"Cytotherapy"},{"key":"1053_CR2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1046\/j.1365-3083.2003.01176.x","volume":"57","author":"K Le Blanc","year":"2003","unstructured":"Le Blanc K, Tammik L, Sundberg B, Haynesworth SE, Ringd\u00e9n O. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol. 2003;57:11\u201320.","journal-title":"Scand J Immunol"},{"key":"1053_CR3","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1002\/jcb.20886","volume":"98","author":"AI Caplan","year":"2006","unstructured":"Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem. 2006;98:1076\u201384.","journal-title":"J Cell Biochem"},{"key":"1053_CR4","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1089\/scd.2007.0153","volume":"17","author":"JW Kang","year":"2008","unstructured":"Kang JW, Kang KS, Koo HC, Park JR, Choi EW, Park YH. Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells. Stem Cells Dev. 2008;17:681\u201393.","journal-title":"Stem Cells Dev"},{"key":"1053_CR5","doi-asserted-by":"publisher","unstructured":"Sutton MT, Bonfield TL. Stem cells: innovations in clinical applications. Stem Cells Int. 2014; doi: 10.1155\/2014\/516278 .","DOI":"10.1155\/2014\/516278"},{"key":"1053_CR6","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.1091\/mbc.E02-02-0105","volume":"13","author":"PA Zuk","year":"2002","unstructured":"Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell. 2002;13:4279\u201395.","journal-title":"Mol Biol Cell"},{"key":"1053_CR7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.2302\/kjm.54.132","volume":"54","author":"BM Strem","year":"2005","unstructured":"Strem BM, Hicok KC, Zhu M, Wulur I, Alfonso Z, Schreiber RE, Fraser JK, Hedrick MH. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med. 2005;54:132\u201341.","journal-title":"Keio J Med"},{"key":"1053_CR8","doi-asserted-by":"crossref","unstructured":"Baer PC, Geiger H. Adipose-derived mesenchymal stromal\/stem cells: tissue localization, characterization, and heterogeneity. Stem Cells Int. 2012;812693","DOI":"10.1155\/2012\/812693"},{"key":"1053_CR9","first-page":"139","volume":"36","author":"CM Reich","year":"2012","unstructured":"Reich CM, Raabe O, Wenisch S, Bridger PS, Kramer M, Arnhold S. Isolation, culture and chondrogenic differentiation of canine adipose tissue- and bone marrow-derived mesenchymal stem cells--a comparative study. Vet Sci Commun. 2012;36:139\u201348.","journal-title":"Vet Sci Commun"},{"key":"1053_CR10","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1089\/ten.tea.2007.0207","volume":"14","author":"M Neupane","year":"2008","unstructured":"Neupane M, Chang C-C, Kiupel M, Yuzbasiyan-Gurkan V. Isolation and characterization of canine adipose-derived mesenchymal stem cells. Tissue Eng. 2008;14:1007\u201315.","journal-title":"Tissue Eng"},{"key":"1053_CR11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3727\/096368909X481764","volume":"9","author":"N Vieira","year":"2010","unstructured":"Vieira N, Brandalise V, Zucconi E, Secco M, Strauss B, Zatz M. Isolation, characterization, and differentiation potential of canine adipose-derived stem cells. Cell Transplant. 2010;9:279\u201389.","journal-title":"Cell Transplant"},{"key":"1053_CR12","first-page":"177","volume":"77","author":"D Astor","year":"2013","unstructured":"Astor D, Hoelzler M, Harman R, Bastian R. Patient factors influencing the concentration of stromal vascular fraction (SVF) for adipose-derived stromal cell (ASC) therapy in dogs. Canine J Vet Res. 2013;77:177\u201382.","journal-title":"Canine J Vet Res"},{"key":"1053_CR13","doi-asserted-by":"publisher","unstructured":"Trzil JE, Masseau I, Webb TL, Chang CH, Dodam JR, Liu H, Quimby JM, Dow SW, Reinero CR. Intravenous adipose-derived mesenchymal stem cell therapy for the treatment of feline asthma: a pilot study. J Feline Med Surg. 2015; doi: 10.1177\/1098612X15604351 .","DOI":"10.1177\/1098612X15604351"},{"key":"1053_CR14","doi-asserted-by":"crossref","first-page":"206","DOI":"10.5966\/sctm.2013-0125","volume":"2","author":"V Russo","year":"2014","unstructured":"Russo V, Yu C, Belliveau P, Hamilton A, Flynn LE. Comparison of human adipose-derived stem cells isolated from subcutaneous, omental, and intrathoracic adipose tissue depots for regenerative applications. Stem Cells Transl Med. 2014;2:206\u201317.","journal-title":"Stem Cells Transl Med"},{"key":"1053_CR15","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1002\/cbin.10090","volume":"37","author":"A Guercio","year":"2013","unstructured":"Guercio A, Di Bella S, Casella S, Di Marco P, Russo C, Piccione G. Canine mesenchymal stem cells (MSCs): characterization in relation to donor age and adipose tissue-harvesting site. Cell Biol Int. 2013;37:789\u201398.","journal-title":"Cell Biol Int"},{"key":"1053_CR16","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/1746-6148-10-131","volume":"10","author":"N Thengchaisri","year":"2014","unstructured":"Thengchaisri N, Wutthiwong T, Kaewmokul S, Sastravaha A. Abdominal obesity is associated with heart disease in dogs. BMC Vet Res. 2014;10:131.","journal-title":"BMC Vet Res"},{"key":"1053_CR17","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1292\/jvms.13-0397","volume":"76","author":"T Kobatashi","year":"2014","unstructured":"Kobatashi T, Koie H, Kusumi A, Kitagawa M, Kanayama K, Otsuji K. Comparative investigation of body composition in male dogs using CT and body fat analysis software. J Vet Med Sci. 2014;76:439\u201346.","journal-title":"J Vet Med Sci"},{"key":"1053_CR18","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s12015-012-9397-0","volume":"8","author":"JF Requicha","year":"2012","unstructured":"Requicha JF, Viegas CA, Albuquerque CM, Azevedo JM, Reis RL, Gomes ME. Effect of anatomical origin and cell passage number on the stemness and osteogenic differentiation potential of canine adipose-derived stem cells. Stem Cell Rev. 2012;8:1211\u201322.","journal-title":"Stem Cell Rev"},{"key":"1053_CR19","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1179\/016164105X63674","volume":"27","author":"I Garc\u00eda-G\u00f3mez","year":"2005","unstructured":"Garc\u00eda-G\u00f3mez I, Goldsmith H, Angulo J, Prados A, L\u00f3pez-Herv\u00e1s P, Cuevas B, Dujovny M, Cuevas P. Angiogenic capacity of human omental stem cells. Neurogical Res. 2005;27:807\u201311.","journal-title":"Neurogical Res"},{"key":"1053_CR20","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1016\/j.jcms.2015.10.002","volume":"43","author":"S Jung","year":"2015","unstructured":"Jung S, Kleineidam B, Kleinheinz J. Regenerative potential of human adipose-derived stromal cells of various origins. J Craniomaxillofac Surg. 2015;43:2144\u201351.","journal-title":"J Craniomaxillofac Surg"},{"key":"1053_CR21","doi-asserted-by":"crossref","unstructured":"Contador D, Ezquer F, Espinosa M, Arango-Rodriguez M, Puebla C, Sobrevia L, Conget P. Dexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells. Exp Biol Med (Maywood).\u00a02015;240:1235\u201346.","DOI":"10.1177\/1535370214566565"},{"issue":"6","key":"1053_CR22","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4252\/wjsc.v4.i6.53","volume":"4","author":"S Vellasamy","year":"2012","unstructured":"Vellasamy S, Sandrasaigaran P, Vidyadaran S, George E, Ramasamy R. Isolation and characterisation of mesenchymal stem cells derived from human placenta tissue. World J Stem Cells. 2012;4(6):53\u201361.","journal-title":"World J Stem Cells"},{"issue":"1","key":"1053_CR23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/(SICI)1097-4652(199910)181:1<67::AID-JCP7>3.0.CO;2-C","volume":"181","author":"PA Conget","year":"1999","unstructured":"Conget PA, Minguell JJ. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol. 1999;181(1):67\u201373.","journal-title":"J Cell Physiol"},{"key":"1053_CR24","doi-asserted-by":"publisher","unstructured":"Ezquer FE, Ezquer ME, Simon V, Conget P. The antidiabetic effect of MSCs in not impaired by insulin prophylaxis and is not improved by second dose of cells. PLoS One. 2011; doi: 10.1371\/journal.pone.0016566 .","DOI":"10.1371\/journal.pone.0016566"},{"key":"1053_CR25","doi-asserted-by":"publisher","unstructured":"Wagner W, Horn P, Castoldi M, Diehlmann A, Bork S, Saffrich R, Benes V, Blake J, Pfister S, Eckstein V, Ho AD. Replicative senescence of mesenchymal stem cells: a continuous and organized process. PLoS One. 2008; doi: 10.1371\/journal.pone.0002213 .","DOI":"10.1371\/journal.pone.0002213"},{"key":"1053_CR26","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)). Method. 2001;25:402\u20138.","journal-title":"Method"},{"key":"1053_CR27","first-page":"6377","volume":"8","author":"L Jing","year":"2015","unstructured":"Jing L, Rui W, Lei Y, Qi W, Qinwan W, Zhengchao N, Yongchun Y, Ji M, Qiuhui P. Knochdown of nestin inhibits proliferation and migration of colorectal cancer cells. Int J Clin Exp Pathol. 2015;8:6377\u201386.","journal-title":"Int J Clin Exp Pathol"},{"key":"1053_CR28","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/978-1-59745-241-0_10","volume":"467","author":"ML Ponce","year":"2009","unstructured":"Ponce ML. Tube formation: an in vitro matrigel angiogenesis assay. Methods Mol Biol. 2009;467:183\u20138.","journal-title":"Methods Mol Biol"},{"key":"1053_CR29","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.cellimm.2009.06.010","volume":"259","author":"KH Yoo","year":"2009","unstructured":"Yoo KH, Jang IK, Lee MW, Kim HE, Yang MS, Eom Y, Lee JE, Kim YJ, Yang SK, Jung HL, Sung KW, Kim CW, Koo HH. Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues. Cell Immunol. 2009;259:150\u20136.","journal-title":"Cell Immunol"},{"key":"1053_CR30","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3109\/10520295.2011.649785","volume":"87","author":"HE Gruber","year":"2012","unstructured":"Gruber HE, Somayaji S, Riley F, Hoelscher GL, Norton HJ, Ingram J. Human adipose-derived mesenchymal stem cells: serial passaging, doubling time and cell senescence. Biotech Histochem. 2012;87:303\u201311.","journal-title":"Biotech Histochem"},{"key":"1053_CR31","doi-asserted-by":"publisher","unstructured":"Murphy MB, Moncivais K, Caplan AI. Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine. Exp Mol Med. 2013; doi: 10.1038\/emm.2013.94 .","DOI":"10.1038\/emm.2013.94"},{"key":"1053_CR32","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/(SICI)1097-4652(199603)166:3<585::AID-JCP13>3.0.CO;2-6","volume":"166","author":"SE Haynesworth","year":"1996","unstructured":"Haynesworth SE, Baber MA, Caplan AI. Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha. J Cell Physiol. 1996;166:585\u201392.","journal-title":"J Cell Physiol"},{"key":"1053_CR33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.yexcr.2015.08.019","volume":"338","author":"Y Nalldijk","year":"2015","unstructured":"Nalldijk Y, Johnson AA, Ishak S, Meisel HJ, Hohaus C, Stolzing A. Migrational changes of mesenchymal stem cells in response to cytokine, growth factors, hypoxia and aging. Exp Cell Res. 2015;338:97\u2013104.","journal-title":"Exp Cell Res"},{"issue":"3","key":"1053_CR34","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/jcp.21068","volume":"212","author":"GE Kilroy","year":"2007","unstructured":"Kilroy GE, Foster SJ, Wu X, Ruiz J, Shrwood S, Heifetz A, Ludlow JW, Stricker DM, Potiny S, Green P, Halvorsen YD, Cheatham B, Storms RW, Gimble JM. Cytokine profile of human adipose-derived stem cells: expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol. 2007;212(3):702\u20139.","journal-title":"J Cell Physiol"},{"key":"1053_CR35","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1073\/pnas.76.4.1809","volume":"76","author":"H Antoniades","year":"1979","unstructured":"Antoniades H, Scher C, Stiles C. Purification of human platelet-derived growth factor. Proc Natl Acad Sci U S A. 1979;76:1809\u201313.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1053_CR36","doi-asserted-by":"crossref","first-page":"8796","DOI":"10.1073\/pnas.84.24.8796","volume":"84","author":"L Claesson-Welsh","year":"1987","unstructured":"Claesson-Welsh L, Ronnstrand L, Heldin C. Biosynthesis and intracellular transport of the receptor for platelet-derived growth factor. Proc Natl Acad Sci U S A. 1987;84:8796\u2013800.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1053_CR37","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.cytogfr.2004.03.001","volume":"15","author":"C Heldin","year":"2004","unstructured":"Heldin C. Platelet-derived growth factor--an introduction. Cytokine Growth Factor Rev. 2004;15:195\u20136.","journal-title":"Cytokine Growth Factor Rev"},{"key":"1053_CR38","doi-asserted-by":"crossref","first-page":"9822","DOI":"10.1016\/S0021-9258(17)36957-0","volume":"269","author":"M Lubinus","year":"1994","unstructured":"Lubinus M, Meier K, Smith E, Gause K, LeRoy E, Trojanowska M. Independent effects of platelet-derived growth factor isoforms on mitogen-activated protein kinase activation and mitogenesis in human dermal fibroblasts. J Biol Chem. 1994;269:9822\u20135.","journal-title":"J Biol Chem"},{"key":"1053_CR39","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1124\/mol.54.6.1007","volume":"54","author":"T Walker","year":"1998","unstructured":"Walker T, Moore S, Lawson M, Panettieri R, Chilvers E. Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation. Mol Pharmacol. 1998;54:1007\u201315.","journal-title":"Mol Pharmacol"},{"key":"1053_CR40","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1126\/science.1846706","volume":"251","author":"DP Bottaro","year":"1991","unstructured":"Bottaro DP, Rubin JS, Faletto DL, et al. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science. 1991;251:802\u20134.","journal-title":"Science"},{"key":"1053_CR41","doi-asserted-by":"crossref","first-page":"11307","DOI":"10.1073\/pnas.97.21.11307","volume":"97","author":"M Schuldiner","year":"2000","unstructured":"Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N. Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A. 2000;97:11307\u201312.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1053_CR42","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1634\/stemcells.22-3-405","volume":"22","author":"S Neuss","year":"2004","unstructured":"Neuss S, Becher E, Woltje M, Tietze L, Jahnen-Dechent W. Functional expression of HGF and HGF receptor\/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair and wound healing. Stem Cells. 2004;22:405\u201314.","journal-title":"Stem Cells"},{"key":"1053_CR43","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1634\/stemcells.2004-0176","volume":"24","author":"G Forte","year":"2006","unstructured":"Forte G, Minieri M, Cossa P, Antenucci D, Sala M, Gnocchi V, Fiaccavento R, Carotenuto F, De Vito P, Baldini PM, Prat M, Di Nardo P. Hepatocyte growth factor effects on Mesenchymal stem cells:proliferation, migration, and differentiation. Stem Cells. 2006;24:23\u201333.","journal-title":"Stem Cells"},{"key":"1053_CR44","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0163-7258(91)90034-J","volume":"52","author":"F Arnold","year":"1991","unstructured":"Arnold F, West DC. Angiogenesis in wound healing. Pharmacol Ther. 1991;52:407\u201322.","journal-title":"Pharmacol Ther"},{"key":"1053_CR45","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1161\/01.CIR.0000102939.04279.75","volume":"108","author":"NP Fam","year":"2003","unstructured":"Fam NP, Verma S, Kutryk M, Stewart DJ. Clinician guide to angiogenesis. Circulation. 2003;108:2613\u20138.","journal-title":"Circulation"},{"key":"1053_CR46","doi-asserted-by":"publisher","unstructured":"Chen L, Tredget EE, Wu PYG, Wu Y. Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS One. 2008; doi: 10.1371\/journal.pone.0001886 .","DOI":"10.1371\/journal.pone.0001886"},{"key":"1053_CR47","doi-asserted-by":"crossref","first-page":"874","DOI":"10.5604\/17322693.1162989","volume":"69","author":"M Pikula","year":"2015","unstructured":"Pikula M, Langa P, Kosikowska P, Trzonkowski P. Stem cells and growth factors in wound healing. Postepy Hig Med Dosw. 2015;69:874\u201385.","journal-title":"Postepy Hig Med Dosw"},{"key":"1053_CR48","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.stem.2008.01.007","volume":"2","author":"A Keating","year":"2008","unstructured":"Keating A. How do mesenchymal stromal cells suppress T cells? Cell Stem Cell. 2008;2:106\u20138.","journal-title":"Cell Stem Cell"},{"key":"1053_CR49","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/nri3209","volume":"12","author":"K Le Blanc","year":"2012","unstructured":"Le Blanc K, Mougiakakos D. Multipotent mesenchymal stromal cells and the innate immune system. Nat Rev Immunol. 2012;12:383\u201396.","journal-title":"Nat Rev Immunol"},{"key":"1053_CR50","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1002\/jcb.23119","volume":"112","author":"K English","year":"2011","unstructured":"English K, Mahon BP. Allogeneic mesenchymal stem cells: agents of immune modulation. J Cell Biochem. 2011;112:1963\u20138.","journal-title":"J Cell Biochem"},{"key":"1053_CR51","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1126\/science.281.5380.1191","volume":"281","author":"DH Munn","year":"1998","unstructured":"Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, Brown C, Mellor AL. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 1998;281:1191\u20133.","journal-title":"Science"},{"key":"1053_CR52","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.4049\/jimmunol.1301828","volume":"192","author":"R Chinnadurai","year":"2014","unstructured":"Chinnadurai R, Copland IB, Patel SR, Galipeau J. IDO-independent suppression of T cell effector function by IFN-\u03b3-licensed human mesenchymal stromal cells. J Immunol. 2014;192:1491\u2013501.","journal-title":"J Immunol"},{"key":"1053_CR53","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.yexcr.2014.03.013","volume":"15","author":"Z Yan","year":"2014","unstructured":"Yan Z, Zhuansun Y, Chen R, Li J, Ran P. Immunomodulation of mesenchymal stromal cells on regulatory T cells and its possible mechanism. Exp Cell Res. 2014;15:65\u201374.","journal-title":"Exp Cell Res"},{"key":"1053_CR54","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jcyt.2014.10.002","volume":"17","author":"DD Bloom","year":"2015","unstructured":"Bloom DD, Centanni JM, Bhatia N, Emler CA, Drier D, Leverson GE, McKenna DH Jr, Gee AP, Lindblad R, Hei DJ, Hematti P. Cytotherapy. 2015;17:140\u201351.","journal-title":"Cytotherapy"},{"key":"1053_CR55","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1089\/scd.2012.0315","volume":"22","author":"S Selleri","year":"2013","unstructured":"Selleri S, Dieng MM, Nicoletti S, Louis I, Beausejour C, Le Deist F, Haddad E. Cord-blood-derived mesenchymal stromal cells downmodulate CD4+ T-cell activation by inducing IL-10-producing Th1 cells. Stem Cells Dev. 2013;22:1063\u201375.","journal-title":"Stem Cells Dev"},{"key":"1053_CR56","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1002\/stem.118","volume":"27","author":"G Ren","year":"2009","unstructured":"Ren G, Su J, Zhang L, Zhao X, Ling W, L'huillie A, Zhang J, Lu Y, Roberts AI, Ji W, Zhang H, Rabson AB, Shi Y. Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression. Stem Cells. 2009;27:1954\u201362.","journal-title":"Stem Cells"},{"key":"1053_CR57","first-page":"106","volume":"2","author":"A Keating","year":"2008","unstructured":"Keating A. Cell how do mesenchymal stromal cells suppress T cells? Stem Cell. 2008;2:106\u20138.","journal-title":"Stem Cell"}],"container-title":["BMC Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-017-1053-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T08:56:32Z","timestamp":1659084992000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-017-1053-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,8]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["1053"],"URL":"https:\/\/doi.org\/10.1186\/s12917-017-1053-0","relation":{},"ISSN":["1746-6148"],"issn-type":[{"value":"1746-6148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,8]]},"article-number":"166"}}