{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:22:46Z","timestamp":1790310166872,"version":"4.1.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31372282"],"award-info":[{"award-number":["31372282"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"China Thousand Talents Program"},{"name":"the Young Talent fund of University Association for Science and Technology in Shaanxi, China","award":["20160236"],"award-info":[{"award-number":["20160236"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Vet Res"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12917-018-1376-5","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T22:16:50Z","timestamp":1519683410000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Characterization of the resistance class 1 integrons in Staphylococcus aureus isolates from milk of lactating dairy cattle in Northwestern China"],"prefix":"10.1186","volume":"14","author":[{"given":"Longping","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1078-7332","authenticated-orcid":false,"given":"Xin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,27]]},"reference":[{"issue":"18","key":"1376_CR1","doi-asserted-by":"publisher","first-page":"3057","DOI":"10.1007\/s00018-010-0389-4","volume":"67","author":"N Malachowa","year":"2010","unstructured":"Malachowa N, DeLeo FR. Mobile genetic elements of Staphylococcus aureus. Cell Mol Life Sci. 2010;67(18):3057\u201371.","journal-title":"Cell Mol Life Sci"},{"issue":"2","key":"1376_CR2","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1128\/MMBR.00056-13","volume":"78","author":"MR Gillings","year":"2014","unstructured":"Gillings MR. Integrons: past, present, and future. Microbiol Mol Biol Rev. 2014;78(2):257\u201377.","journal-title":"Microbiol Mol Biol Rev"},{"issue":"8","key":"1376_CR3","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1038\/nrmicro1462","volume":"4","author":"D Mazel","year":"2006","unstructured":"Mazel D. Integrons: agents of bacterial evolution. Nat Rev Microbiol. 2006;4(8):608\u201320.","journal-title":"Nat Rev Microbiol"},{"issue":"6","key":"1376_CR4","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1089\/mdr.2013.0198","volume":"20","author":"F Firoozeh","year":"2014","unstructured":"Firoozeh F, Zahraei-Salehi T, Shahcheraghi F. Molecular clonality and detection of class 1 integron in multidrug-resistant Salmonella enterica isolates from animal and human in Iran. Microb Drug Resist. 2014;20(6):517\u201324.","journal-title":"Microb Drug Resist"},{"issue":"3","key":"1376_CR5","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.ijantimicag.2012.05.017","volume":"40","author":"K Wu","year":"2012","unstructured":"Wu K, Wang F, Sun J, Wang Q, Chen Q, Yu S, Rui Y. Class 1 integron gene cassettes in multidrug-resistant gram-negative bacteria in southern China. Int J Antimicrob Agents. 2012;40(3):264\u20137.","journal-title":"Int J Antimicrob Agents"},{"issue":"18","key":"1376_CR6","doi-asserted-by":"publisher","first-page":"7118","DOI":"10.1073\/pnas.0306466101","volume":"101","author":"S Nandi","year":"2004","unstructured":"Nandi S, Maurer JJ, Hofacre C, Summers AO. Gram-positive bacteria are a major reservoir of class 1 antibiotic resistance integrons in poultry litter. Proc Natl Acad Sci. 2004;101(18):7118\u201322.","journal-title":"Proc Natl Acad Sci"},{"issue":"10","key":"1376_CR7","doi-asserted-by":"publisher","first-page":"980","DOI":"10.1111\/j.1469-0691.2007.01782.x","volume":"13","author":"Z Xu","year":"2007","unstructured":"Xu Z, Shi L, Zhang C, Zhang L, Li X, Cao Y, Li L, Yamasaki S. Nosocomial infection caused by class 1 integron-carrying Staphylococcus aureus in a hospital in South China. Clin Microbiol Infec. 2007;13(10):980\u20134.","journal-title":"Clin Microbiol Infec."},{"issue":"5","key":"1376_CR8","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1111\/j.1469-0691.2010.03379.x","volume":"17","author":"Z Xu","year":"2011","unstructured":"Xu Z, Li L, Shirtliff ME, Peters BM, Li B, Peng Y, Alam MJ, Yamasaki S, Shi L. Resistance class 1 integron in clinical methicillin-resistant Staphylococcus aureus strains in southern China, 2001-2006. Clin Microbiol Infec. 2011;17(5):714\u20138.","journal-title":"Clin Microbiol Infec"},{"issue":"3","key":"1376_CR9","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1007\/s00284-008-9187-8","volume":"57","author":"Z Xu","year":"2008","unstructured":"Xu Z, Li L, Alam MJ, Zhang L, Yamasaki S, Shi L. First confirmation of integron-bearing methicillin-resistant Staphylococcus aureus. Curr Microbiol. 2008;57(3):264\u20138.","journal-title":"Curr Microbiol"},{"issue":"3","key":"1376_CR10","doi-asserted-by":"publisher","first-page":"e0116699","DOI":"10.1371\/journal.pone.0116699","volume":"10","author":"L Li","year":"2015","unstructured":"Li L, Zhou L, Wang L, Xue H, Zhao X. Characterization of methicillin-resistant and -susceptible staphylococcal isolates from bovine milk in northwestern china. PLoS One. 2015;10(3):e0116699.","journal-title":"PLoS One"},{"key":"1376_CR11","first-page":"M31","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals: informational supplement","author":"Clinical and Laboratory Standards Institute","year":"2004","unstructured":"Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals: informational supplement. Wayne: CLSI document; 2004. p. M31\u2013S1."},{"key":"1376_CR12","first-page":"M100","volume-title":"Performance standards for antimicrobial susceptibility testing; twenty-first informational supplement","author":"Clinical and Laboratory Standards Institute","year":"2011","unstructured":"Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; twenty-first informational supplement. Wayne: CLSI document; 2011. p. M100\u2013S21."},{"key":"1376_CR13","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1186\/s12917-015-0492-8","volume":"11","author":"L Li","year":"2015","unstructured":"Li L, Feng W, Zhang Z, Xue H, Zhao X. Macrolide-lincosamide-streptogramin resistance phenotypes and genotypes of coagulase-positive Staphylococcus aureus and coagulase-negative staphylococcal isolates from bovine mastitis. BMC Vet Res. 2015;11:168.","journal-title":"BMC Vet Res"},{"issue":"1","key":"1376_CR14","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/j.1574-6968.2005.00025.x","volume":"254","author":"J Su","year":"2006","unstructured":"Su J, Shi L, Yang L, Xiao Z, Li X, Yamasaki S. Analysis of integrons in clinical isolates of Escherichia coli in China during the last six years. FEMS Microbiol Lett. 2006;254(1):75\u201380.","journal-title":"FEMS Microbiol Lett"},{"issue":"1","key":"1376_CR15","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1128\/AAC.39.1.185","volume":"39","author":"C Levesque","year":"1995","unstructured":"Levesque C, Piche L, Larose C, Roy PH. PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob Agents Chemother. 1995;39(1):185\u201391.","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"1376_CR16","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1111\/j.1574-6976.2009.00175.x","volume":"33","author":"SR Partridge","year":"2009","unstructured":"Partridge SR, Tsafnat G, Coiera E, Iredell JR. Gene cassettes and cassette arrays in mobile resistance integrons. FEMS Microbiol Rev. 2009;33(4):757\u201384.","journal-title":"FEMS Microbiol Rev"},{"issue":"4","key":"1376_CR17","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1093\/jac\/dkl020","volume":"57","author":"MT Blahna","year":"2006","unstructured":"Blahna MT, Zalewski CA, Reuer J, Kahlmeter G, Foxman B, Marrs CF. The role of horizontal gene transfer in the spread of trimethoprim-sulfamethoxazole resistance among uropathogenic Escherichia coli in Europe and Canada. J Antimicrob Chemother. 2006;57(4):666\u201372.","journal-title":"J Antimicrob Chemother"},{"key":"1376_CR18","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.mib.2017.03.002","volume":"38","author":"MR Gillings","year":"2017","unstructured":"Gillings MR. Class 1 integrons as invasive species. Curr Opin Microbiol. 2017;38:10\u20135.","journal-title":"Curr Opin Microbiol"},{"issue":"2","key":"1376_CR19","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1078\/1438-4221-00197","volume":"292","author":"DA Rowe-Magnus","year":"2002","unstructured":"Rowe-Magnus DA, Mazel D. The role of integrons in antibiotic resistance gene capture. Int J Med Microbiol. 2002;292(2):115\u201325.","journal-title":"Int J Med Microbiol"},{"issue":"5","key":"1376_CR20","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/S1369-5274(99)00004-1","volume":"2","author":"DA Rowe-Magnus","year":"1999","unstructured":"Rowe-Magnus DA, Mazel D. Resistance gene capture. Curr Opin Microbiol. 1999;2(5):483\u20138.","journal-title":"Curr Opin Microbiol"},{"issue":"6","key":"1376_CR21","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1093\/jac\/42.6.689","volume":"42","author":"P Martinez-Freijo","year":"1998","unstructured":"Martinez-Freijo P, Fluit AC, Schmitz FJ, Grek VS, Verhoef J, Jones ME. Class I integrons in gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compounds. J Antimicrob Chemother. 1998;42(6):689\u201396.","journal-title":"J Antimicrob Chemother"}],"container-title":["BMC Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-018-1376-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T07:02:27Z","timestamp":1551250947000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-018-1376-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,27]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["1376"],"URL":"https:\/\/doi.org\/10.1186\/s12917-018-1376-5","relation":{},"ISSN":["1746-6148"],"issn-type":[{"value":"1746-6148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,27]]},"assertion":[{"value":"10 January 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 February 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Milk samples were taken by farmers and no ethics approval was considered necessary.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"59"}}