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The competent authority was informed. According to the information of our ethics committee (Regierungspr\u00e4sidium Giessen, Dezernat 54 \u2013 Veterin\u00e4rwesen\/Verbraucherschutz, Wetzlar, Germany, ethics committee number: GI 17\/18), a particular approval for the study was not needed, because the study itself was not the indication of blood sampling and did not require taking an additional amount of blood.For the diseased dogs, the measurement of CRP was part of the routine clinical chemical profile, whereby 1\u20132 1.2\u00a0cmheparin tubes for measurement of CRP on the ABX Pentra 400 and the remainder clinical chemical measurands was required. Evaluation on the Point Reader\u2122 V was conducted from superfluous heparinized plasma as only 10\u00a0\u03bcl were necessary. The healthy dogs included in this study were presented in the Department of Veterinary Clinical Sciences in Giessen, Germany, either for health assessments or as blood donors. 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