{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T08:45:48Z","timestamp":1746693948109,"version":"3.37.3"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Vet Res"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Umbilical vein bacterial infections may cause liver abscesses during bacterial ascent. A single liver abscess can be surgically treated by marsupialization, but a risk of recurrence or non-healing remains. Moreover, there is no effective treatment for multiple abscesses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 17-day-old Holstein female calf exhibited reduced general condition, swelling and drainage of the umbilicus, and pressure sores in the area of the carpus, resulting in reluctance to stand up. The umbilicus showed pain at palpation; deep abdominal palpation indicated a swollen umbilical vein coursing from the umbilicus toward the liver. Ultrasonography confirmed a swollen umbilical vein with pus accumulation and multiple abscesses in the liver. Contrast-enhanced computed tomography (CT) examination confirmed that the swollen umbilical vein with fluid continued to the liver, and multiple unenhanced lesions, most likely abscesses, were confirmed in the liver. Partial hepatectomy was performed to remove as many abscesses as possible. For the resection, a vessel sealing device (LigaSureTM) was used to excise a part of the left liver lobe. As we could not remove all the abscesses in the liver during the operation, cefazolin sodium (5 mg\/kg) was administered for 14 days after surgery. Post-operatively, blood accumulation was observed in the abdominal cavity, but no signs of peritonitis were found. The calf returned to the farm on day 38 after surgery. Follow-up information was obtained after 1 year, and complications were not reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To our knowledge, this is the first report of partial hepatectomy using a vessel sealing device for a calf with multiple liver abscesses. This case report suggests that the combination of partial hepatectomy and long-term administration of antibacterial drugs may restore the health of calves with multiple liver abscesses.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12917-021-02750-y","type":"journal-article","created":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T20:02:46Z","timestamp":1612382566000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Partial hepatectomy for treatment of multiple liver abscess in a calf: a case report"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1535-1391","authenticated-orcid":false,"given":"Reiichiro","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutaka","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiki","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koki","family":"Tanimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoko","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsumi","family":"Tatsuzawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiho","family":"Nakui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Satoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Fadul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"key":"2750_CR1","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/B978-141603591-6.10081-8","volume-title":"Food animal practice","author":"DM Rings","year":"2009","unstructured":"Rings DM, Anderson DE. Umbilical surgery in calves. In: Anderson DE, Rings DM, editors. Food animal practice. St. Louis: Saunders Elsevier; 2009. p. 391\u20133."},{"key":"2750_CR2","first-page":"379","volume-title":"Large Animal Internal Medicine","author":"JK House","year":"2020","unstructured":"House JK. Umbilical enlargement. In: Smith BP, Van Metre DC, Pusterla N, editors. Large Animal Internal Medicine. 6th ed. St. Louis: Elsevier; 2020. p. 379\u201380.","edition":"6"},{"key":"2750_CR3","first-page":"203","volume":"25","author":"JE Kosovsky","year":"1989","unstructured":"Kosovsky JE, Manfra-Marretta S, Matthiesen DT, Patnaik AK. Giessen Univ. (Germany, F.R.). Fachbereich veterinaermedizin. Results of partial hepatectomy in 18 dogs with hepatocellular carcinoma. J Am Anim Hosp Assoc. 1989;25:203\u20136.","journal-title":"J Am Anim Hosp Assoc."},{"key":"2750_CR4","first-page":"505","volume":"11","author":"GM Baxter","year":"1989","unstructured":"Baxter GM. Umbilical masses in calves: Diagnosis, treatment and complications. Compend Contin Educ Pract Vet. 1989;11:505\u201313.","journal-title":"Compend Contin Educ Pract Vet."},{"key":"2750_CR5","first-page":"1531","volume":"185","author":"AM Trent","year":"1984","unstructured":"Trent AM, Smith DF. Surgical management of umbilical masses with associated umbilical cord remnant infections in calves. J Am Vet Med Assoc. 1984;185:1531\u20134.","journal-title":"J Am Vet Med Assoc."},{"key":"2750_CR6","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1111\/j.1532-950X.1993.tb00380.x","volume":"22","author":"A Steiner","year":"1993","unstructured":"Steiner A, Christoph JL, Oertle C. Marsupialization of umbilical abscesses with involvement of the liver in 13 calves. Vet Surg. 1993;22:184\u20139.","journal-title":"Vet Surg."},{"key":"2750_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cvfa.2007.10.002","volume":"24","author":"JF Mee","year":"2008","unstructured":"Mee JF. Newborn dairy calf management. Vet Clin North Am Food Anim Pract. 2008;24:1\u201317.","journal-title":"Vet Clin North Am Food Anim Pract."},{"key":"2750_CR8","first-page":"548","volume-title":"Rebhun\u2019s Diseases of Dairy Cattle","author":"TJ Divers","year":"2018","unstructured":"Divers TJ. Urinary Tract Diseases. In: Peek SF, Divers TJ, editors. Rebhun\u2019s Diseases of Dairy Cattle. 3rd ed. St. Louis: Elsevier; 2018. p. 548\u201352.","edition":"3"},{"key":"2750_CR9","first-page":"70","volume":"45","author":"WN Grover","year":"2011","unstructured":"Grover WN, Godden S. Efficacy of a new navel dip to prevent umbilical infection in dairy calves. Am Assoc Bovine Practitioners. 2011;45:70\u20137.","journal-title":"Am Assoc Bovine Practitioners"},{"key":"2750_CR10","first-page":"35","volume":"16","author":"N Kili\u00e7","year":"2005","unstructured":"Kili\u00e7 N, Derinceg\u00f6z O\u00d6, Yayging\u00fcl R. Surgical correction of umbilical disease in calves: a retrospective study of 95 cases. YY\u00dc Vet Fak Derg. 2005;16:35\u20138.","journal-title":"YY\u00dc Vet Fak Derg."},{"key":"2750_CR11","first-page":"40","volume":"72","author":"LE Yanmaz","year":"2017","unstructured":"Yanmaz LE, Dogan E, Okumus Z, Kaya M, Hayirli A. Estimation of outcome of umbilical diseases based on clinical examination: A retrospective study involving 322 calves. Isr J Vet Med. 2017;72:40\u20134.","journal-title":"Isr J Vet Med."},{"key":"2750_CR12","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1111\/j.1532-950X.1988.tb00283.x","volume":"17","author":"JE Parker","year":"1988","unstructured":"Parker JE, Gaughan EM. Partial hepatic resection for treatment of a single liver abscess in a dairy heifer. Vet Surg. 1988;17:87\u20139.","journal-title":"Vet Surg."},{"key":"2750_CR13","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1097\/00006454-200211000-00025","volume":"21","author":"D Alberti","year":"2002","unstructured":"Alberti D, Borsellino A, Locatelli C, Nani R, Cheli M, Torre G, et al. Percutaneous transhepatic alcoholization: a new therapeutic strategy in children with chronic granulomatous disease and liver abscess. Pediatr Infect Dis J. 2002;21:1081\u20133.","journal-title":"Pediatr Infect Dis J."},{"key":"2750_CR14","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1111\/j.1740-8261.1998.tb01621.x","volume":"39","author":"LA Schwarz","year":"1998","unstructured":"Schwarz LA, Penninck DG, Leveille-Webster C. Hepatic abscesses in 13 dogs: a review of the ultrasonographic findings, clinical data and therapeutic options. Vet Radiol Ultrasound. 1998;39:357\u201365.","journal-title":"Vet Radiol Ultrasound."},{"key":"2750_CR15","first-page":"25","volume":"2","author":"A Zatelli","year":"2003","unstructured":"Zatelli A, Bonfanti U. Drenaggio ed alcolizzazione percutanei ecoassistiti delle cisti epatiche del cane e del gatto. Veterinaria. 2003;2:25\u20138.","journal-title":"Veterinaria."},{"key":"2750_CR16","doi-asserted-by":"publisher","first-page":"34","DOI":"10.5326\/0410034","volume":"41","author":"A Zatelli","year":"2005","unstructured":"Zatelli A, Bonfanti U, Zini E, D'Ippolito P, Bussadori C. Percutaneous drainage and alcoholization of hepatic abscesses in five dogs and a cat. J Am Anim Hosp Assoc. 2005;41:34\u20138.","journal-title":"J Am Anim Hosp Assoc."},{"key":"2750_CR17","first-page":"107","volume":"25","author":"R Sato","year":"2019","unstructured":"Sato R, Shinozuka Y, Onda K, Ochiai H, Yamada K. Evaluation of marsupialization combined with long-term administration of antibacterial agents in calves with omphalophlebitis and secondary liver abscess. Large Anim Rev. 2019;25:107\u201310.","journal-title":"Large Anim Rev."},{"key":"2750_CR18","first-page":"218","volume":"24","author":"DL Diefenderfer","year":"1983","unstructured":"Diefenderfer DL, Brightling P. Dysuria due to urachal abscessation in calves diagnosed by contrast radiography. Can Vet J. 1983;24:218\u201321.","journal-title":"Can Vet J."},{"key":"2750_CR19","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1111\/vsu.12433","volume":"45","author":"E Marchionatti","year":"2016","unstructured":"Marchionatti E, Nichols S, Babkine M, Fecteau G, Francoz D, Lard\u00e9 H, et al. Surgical management of omphalophlebitis and long term outcome in calves: 39 cases (2008-2013). Vet Surg. 2016;45:194\u2013200.","journal-title":"Vet Surg."},{"key":"2750_CR20","first-page":"170","volume":"37","author":"MJ Lopez","year":"1996","unstructured":"Lopez MJ, Markel MD. Umbilical artery marsupialization in a calf. Can Vet J. 1996;37:170\u20131.","journal-title":"Can Vet J."},{"key":"2750_CR21","first-page":"103","volume":"35","author":"PC Simon","year":"1971","unstructured":"Simon PC, Stovell PL. Isolation of Sphaerophorus necrophorus from bovine hepatic abscesses in British Columbia. Can J Comp Med. 1971;35:103\u20136.","journal-title":"Can J Comp Med."},{"key":"2750_CR22","first-page":"387","volume":"53","author":"P Sprake","year":"2012","unstructured":"Sprake P, Gold JR. Corynebacterium pseudotuberculosis liver abscess in a mature alpaca (Lama pacos). Can Vet J. 2012;53:387\u201390.","journal-title":"Can Vet J."},{"key":"2750_CR23","doi-asserted-by":"publisher","first-page":"e7969","DOI":"10.1097\/MD.0000000000007969","volume":"96","author":"H Morioka","year":"2017","unstructured":"Morioka H, Iguchi M, Kuzuya T, Mikamo H, Yagi T. Recurrent bacteremia and liver abscess caused by Clostridium difficile: A case report. Medicine (Baltimore). 2017;96:e7969.","journal-title":"Medicine (Baltimore)."},{"key":"2750_CR24","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.anaerobe.2016.09.007","volume":"42","author":"NU Toprak","year":"2016","unstructured":"Toprak NU, Balkose G, Durak D, Dulundu E, Demirba\u015f T, Yegen C, et al. Anaerobe. Clostridium difficile: A rare cause of pyogenic liver abscess. 2016;42:108\u201310.","journal-title":"Anaerobe. Clostridium difficile: A rare cause of pyogenic liver abscess."},{"key":"2750_CR25","first-page":"1297","volume":"186","author":"SL Fubini","year":"1985","unstructured":"Fubini SL, Ducharme NG, Murphy JP, Smith DF. Vagus indigestion syndrome resulting from a liver abscess in dairy cows. J Am Vet Med Assoc. 1985;186:1297\u2013300.","journal-title":"J Am Vet Med Assoc."},{"key":"2750_CR26","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.2460\/javma.2004.225.1225","volume":"225","author":"JM Liptak","year":"2004","unstructured":"Liptak JM, Dernell WS, Monnet E, Powers BE, Bachand AM, Kenney JG, et al. Massive hepatocellular carcinoma in dogs: 48 Cases (1992-2002). J Am Vet Med Assoc. 2004;225:1225\u201330.","journal-title":"J Am Vet Med Assoc."},{"key":"2750_CR27","doi-asserted-by":"publisher","first-page":"168","DOI":"10.4174\/astr.2020.98.4.168","volume":"98","author":"H Kim","year":"2020","unstructured":"Kim H, Lee SJ, Yoon M. Alpha-fetoprotein is correlated with intrahepatic recurrence of hepatocellular carcinoma after a hepatectomy. Ann Surg Treat Res. 2020;98:168\u201376.","journal-title":"Ann Surg Treat Res."},{"key":"2750_CR28","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.ijsu.2020.04.047","volume":"82","author":"G Torzilli","year":"2020","unstructured":"Torzilli G, McCormack L, Pawlik T. Parenchyma-sparing liver resections. Int J Surg. 2020;82:192\u20137.","journal-title":"Int J Surg."},{"key":"2750_CR29","doi-asserted-by":"crossref","first-page":"243","DOI":"10.2460\/javma.1996.208.02.243","volume":"208","author":"ET Farrar","year":"1996","unstructured":"Farrar ET, Washabau RJ, Saunders HM. Hepatic abscesses in dogs: 14 cases (1982-1994). J Am Vet Med Assoc. 1996;208:243\u20137.","journal-title":"J Am Vet Med Assoc."},{"key":"2750_CR30","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1080\/13651820310001117","volume":"5","author":"RW Strong","year":"2003","unstructured":"Strong RW, Fawcett J, Lynch SV, Wall DR. Hepatectomy for pyogenic liver abscess. HPB (Oxford). 2003;5:86\u201390.","journal-title":"HPB (Oxford)."},{"key":"2750_CR31","first-page":"e1394","volume":"31","author":"SR Pais-Costa","year":"2018","unstructured":"Pais-Costa SR, Araujo SLM, Figueiredo VN. Hepatectomy for pyogenic liver abscess treatment: exception approach? Arq Bras Cir Dig. 2018;31:e1394.","journal-title":"Arq Bras Cir Dig."},{"key":"2750_CR32","first-page":"95","volume":"43","author":"M Cromheecke","year":"1991","unstructured":"Cromheecke M, Wijffels RT, Meijer D, Hoekstra HJ. Hepatic resection: haemostatic control by means of compression sutures: a new method. Neth J Surg. 1991;43:95\u20138.","journal-title":"Neth J Surg."},{"key":"2750_CR33","first-page":"33","volume":"17","author":"A Chiappa","year":"2008","unstructured":"Chiappa A, Bertani E, Biffi R, Zbar AP, Viale G, Pruneri G, et al. Effectiveness of LigaSure diathermy coagulation in liver surgery. Surg Technol Int. 2008;17:33\u20138.","journal-title":"Surg Technol Int."},{"key":"2750_CR34","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1111\/j.1532-950X.2010.00719.x","volume":"39","author":"M Risselada","year":"2010","unstructured":"Risselada M, Ellison GW, Bacon NJ, Polyak MM, van Gilder J, Kirkby K, et al. Comparison of 5 surgical techniques for partial liver lobectomy in the dog for intraoperative blood loss and surgical time. Vet Surg. 2010;39:856\u20132.","journal-title":"Vet Surg."},{"key":"2750_CR35","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1007\/s00595-016-1306-8","volume":"46","author":"K Wakayama","year":"2016","unstructured":"Wakayama K, Kamiyama T, Yokoo H, Kakisaka T, Orimo T, Shimada S, et al. Our technique of preceding diaphragm resection and partial mobilization of the hepatic right lobe using a vessel sealing device (LigaSure\u2122) for huge hepatic tumors with diaphragm invasion. Surg Today. 2016;46:1224\u20139.","journal-title":"Surg Today."},{"key":"2750_CR36","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1080\/01652176.2013.875240","volume":"33","author":"BA Schotanus","year":"2013","unstructured":"Schotanus BA, Penning LC, Spee B. Potential of regenerative medicine techniques in canine hepatology. Vet Q. 2013;33:207\u201316.","journal-title":"Vet Q."}],"container-title":["BMC Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-021-02750-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12917-021-02750-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-021-02750-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T14:45:35Z","timestamp":1724424335000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-021-02750-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,3]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["2750"],"URL":"https:\/\/doi.org\/10.1186\/s12917-021-02750-y","relation":{},"ISSN":["1746-6148"],"issn-type":[{"type":"electronic","value":"1746-6148"}],"subject":[],"published":{"date-parts":[[2021,2,3]]},"assertion":[{"value":"9 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was performed according to owner\u2019s agreement for the advanced informed written consents.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"We obtained written informed consents from the owner for the use of information and clinical data of the present case in a publication. Written informed consent was finally obtained from the owner for the publication of this case report.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"67"}}