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Very few studies investigated the association between nasal microbiota and factors such as facial\/body conformation, age, and environment in dogs. The objectives are to investigate variations in NM in healthy dogs with different facial and body conformations. A total of 46 dogs of different age, living environment and from 3 different breed groups were recruited: 22 meso\u2212\/dolichocephalic medium to large breed dogs, 12 brachycephalic dogs and 12 terrier breeds. The nasal bacterial microbiota was assessed through sequencing of 16S rRNA gene (V1-V3 regions) amplicons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We showed major differences in the NM composition together with increased richness and \u03b1-diversity in brachycephalic dogs, compared to meso\u2212\/dolichocephalic medium to large dogs and dogs from terrier breeds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Healthy brachycephalic breeds and their unique facial conformation is associated with a distinct NM profile. Description of the NM in healthy dogs serves as a foundation for future researches assessing the changes associated with disease and the modulation of NM communities as a potential treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12917-021-03055-w","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T05:02:44Z","timestamp":1637730164000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs"],"prefix":"10.1186","volume":"17","author":[{"given":"Emilie","family":"Vangrinsven","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"Fastr\u00e8s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Taminiau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Billen","family":"Fr\u00e9d\u00e9ric","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges","family":"Daube","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile","family":"Clercx","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,24]]},"reference":[{"issue":"12","key":"3055_CR1","doi-asserted-by":"publisher","first-page":"e85507","DOI":"10.1371\/journal.pone.0085507","volume":"8","author":"VR Ramakrishnan","year":"2013","unstructured":"Ramakrishnan VR, Feazel LM, Gitomer SA, Ir D, Robertson CE, Frank DN. 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