{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T16:08:49Z","timestamp":1782749329660,"version":"3.54.5"},"reference-count":71,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Grant No. 32072902"],"award-info":[{"award-number":["Grant No. 32072902"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"crossref","award":["2021YFF0703000"],"award-info":[{"award-number":["2021YFF0703000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Vet Res"],"DOI":"10.1186\/s12917-025-04817-6","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T09:19:43Z","timestamp":1748337583000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A virulent escherichia coli O121-B2-ST131 strain causes hemorrhagic pneumonia in mink: evidence from pathogenicity and animal challenge experiments"],"prefix":"10.1186","volume":"21","author":[{"given":"Yumeng","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"YanYang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dexing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenhong","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junwei","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,27]]},"reference":[{"issue":"1","key":"4817_CR1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s44280-023-00004-0","volume":"1","author":"CKP Mok","year":"2023","unstructured":"Mok CKP, Qin K. Mink infection with influenza A viruses: an ignored intermediate host? One Health Adv. 2023;1(1):5.","journal-title":"One Health Adv"},{"issue":"3","key":"4817_CR2","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s13353-022-00689-w","volume":"63","author":"A Barua","year":"2022","unstructured":"Barua A, Grot N, Plawski A. The basis of mink susceptibility to SARS-CoV-2 infection. J Appl Genet. 2022;63(3):543\u201355.","journal-title":"J Appl Genet"},{"issue":"2","key":"4817_CR3","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1111\/tbed.14028","volume":"69","author":"J Ren","year":"2022","unstructured":"Ren J, Liu W, Sun N, Zhang P, Yin M, Guo L, Zhang H, Cheng S. Isolation and pathogenicity analysis of mink orthoreoviruses. Transbound Emerg Dis. 2022;69(2):623\u201331.","journal-title":"Transbound Emerg Dis"},{"key":"4817_CR4","doi-asserted-by":"publisher","first-page":"199208","DOI":"10.1016\/j.virusres.2023.199208","volume":"336","author":"SM Vahedi","year":"2023","unstructured":"Vahedi SM, Salek Ardestani S, Banabazi MH, Clark F. Epidemiology, pathogenesis, and diagnosis of Aleutian disease caused by Aleutian mink disease virus: A literature review with a perspective of genomic breeding for disease control in American mink (Neogale vison). Virus Res. 2023;336:199208.","journal-title":"Virus Res"},{"issue":"8","key":"4817_CR5","doi-asserted-by":"publisher","first-page":"e01451","DOI":"10.1128\/MRA.01451-20","volume":"10","author":"KTT Kwok","year":"2021","unstructured":"Kwok KTT, de Rooij MMT, Sinartio FF, Smit LAM, Koopmans MPG, Phan MVT. Genome Sequence of a Minacovirus Strain from a Farmed Mink in The Netherlands. Microbiol Resour Announc. 2021;10(8):e01451.","journal-title":"Microbiol Resour Announc"},{"issue":"2","key":"4817_CR6","first-page":"122","volume":"83","author":"X Bai","year":"2019","unstructured":"Bai X, Liu SG, Zhao JJ, Cheng YN, Zhang HL, Hu B, Zhang L, Shi QM, Zhang ZQ, Wu TL, et al. Epidemiology and molecular characterization of the antimicrobial resistance of Pseudomonas aeruginosa in Chinese mink infected by hemorrhagic pneumonia. Can J Vet Res-Rev Can Rech Vet. 2019;83(2):122\u201332.","journal-title":"Can J Vet Res-Rev Can Rech Vet"},{"issue":"4","key":"4817_CR7","first-page":"256","volume":"82","author":"YD Zhao","year":"2018","unstructured":"Zhao YD, Guo LL, Li J, Fang BH, Huang XH. Molecular epidemiology, antimicrobial susceptibility, and pulsed-field gel electrophoresis genotyping of Pseudomonas aeruginosa isolates from mink. Can J Vet Res-Rev Can Rech Vet. 2018;82(4):256\u201363.","journal-title":"Can J Vet Res-Rev Can Rech Vet"},{"issue":"1","key":"4817_CR8","doi-asserted-by":"publisher","first-page":"17291","DOI":"10.1038\/s41598-017-17681-8","volume":"7","author":"W Jian-Li","year":"2017","unstructured":"Jian-Li W, Yuan-Yuan S, Shou-Yu G, Fei-Fei D, Jia-Yu Y, Xue-Hua W, Yong-Feng Z, Shi-Jin J, Zhi-Jing X. Serotype and virulence genes of Klebsiella pneumoniae isolated from mink and its pathogenesis in mice and mink. Sci Rep. 2017;7(1):17291.","journal-title":"Sci Rep"},{"issue":"3","key":"4817_CR9","first-page":"199","volume":"77","author":"CM Salomonsen","year":"2013","unstructured":"Salomonsen CM, Boye M, Hoiby N, Jensen TH, Hammer AS. Comparison of histological lesions in mink with acute hemorrhagic pneumonia associated with Pseudomonas aeruginosa or Escherichia coli. Can J Vet Res-Rev Can Rech Vet. 2013;77(3):199\u2013204.","journal-title":"Can J Vet Res-Rev Can Rech Vet"},{"issue":"11","key":"4817_CR10","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.3382\/ps\/pev256","volume":"94","author":"S De Carli","year":"2015","unstructured":"De Carli S, Ikuta N, Lehmann FKM, da Silveira VP, de Melo PG, Fonseca ASK, Lunge VR. Virulence gene content in Escherichia coli isolates from poultry flocks with clinical signs of colibacillosis in Brazil. Poult Sci. 2015;94(11):2635\u201340.","journal-title":"Poult Sci"},{"issue":"5","key":"4817_CR11","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1023\/A:1024741719361","volume":"27","author":"RJ Tibbetts","year":"2003","unstructured":"Tibbetts RJ, White DG, Dyer NW, Giddings CW, Nolan LK. Characterization of Escherichia coli isolates incriminated in colisepticaemia in mink. Vet Res Commun. 2003;27(5):341\u201357.","journal-title":"Vet Res Commun"},{"key":"4817_CR12","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.micpath.2018.01.041","volume":"116","author":"A Derakhshandeh","year":"2018","unstructured":"Derakhshandeh A, Eraghi V, Boroojeni AM, Niaki MA, Zare S, Naziri Z. Virulence factors, antibiotic resistance genes and genetic relatedness of commensal Escherichia coli isolates from dogs and their owners. Microb Pathog. 2018;116:241\u20135.","journal-title":"Microb Pathog"},{"issue":"3","key":"4817_CR13","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.tvjl.2011.06.038","volume":"192","author":"C Tan","year":"2012","unstructured":"Tan C, Tang X, Zhang X, Ding Y, Zhao Z, Wu B, Cai X, Liu Z, He Q, Chen H. Serotypes and virulence genes of extraintestinal pathogenic Escherichia coli isolates from diseased pigs in China. Vet J. 2012;192(3):483\u20138.","journal-title":"Vet J"},{"key":"4817_CR14","doi-asserted-by":"publisher","first-page":"829532","DOI":"10.1155\/2013\/829532","volume":"2013","author":"GM Rimoldi","year":"2013","unstructured":"Rimoldi GM, Moeller RB Jr. Escherichia fergusonii Associated with Pneumonia in a Beef Cow. J Vet Med. 2013;2013:829532.","journal-title":"J Vet Med"},{"issue":"6","key":"4817_CR15","first-page":"663","volume":"53","author":"LK Handt","year":"2003","unstructured":"Handt LK, Stoffregen DA, Prescott JS, Pouch WJ, Ngai DT, Anderson CA, Gatto NT, DebRoy C, Fairbrother JM, Motzel SL, et al. Clinical and microbiologic characterization of hemorrhagic pneumonia due to extraintestinal pathogenic Escherichia coli in four young dogs. Comp Med. 2003;53(6):663\u201370.","journal-title":"Comp Med"},{"issue":"8","key":"4817_CR16","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/j.1863-2378.2007.01067.x","volume":"54","author":"R Sura","year":"2007","unstructured":"Sura R, Van Kruiningen HJ, DebRoy C, Hinckley LS, Greenberg KJ, Gordon Z, French RA. Extraintestinal pathogenic Escherichia coli-induced acute necrotizing pneumonia in cats. Zoonoses Public Health. 2007;54(8):307\u201313.","journal-title":"Zoonoses Public Health"},{"issue":"5","key":"4817_CR17","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1177\/104063870902100504","volume":"21","author":"MA Highland","year":"2009","unstructured":"Highland MA, Byrne BA, Debroy C, Samitz EM, Peterson TS, Oslund KL. Extraintestinal pathogenic Escherichia coli-induced pneumonia in three kittens and fecal prevalence in a clinically healthy cohort population. J Vet Diagn Invest. 2009;21(5):609\u201315.","journal-title":"J Vet Diagn Invest"},{"key":"4817_CR18","first-page":"3917841","volume":"2019","author":"J Qiu","year":"2019","unstructured":"Qiu J, Jiang Z, Ju Z, Zhao X, Yang J, Guo H, Sun S. Molecular and Phenotypic Characteristics of Escherichia coli Isolates from Farmed Minks in Zhucheng. China Biomed Res Int. 2019;2019:3917841.","journal-title":"China Biomed Res Int"},{"key":"4817_CR19","doi-asserted-by":"publisher","first-page":"781068","DOI":"10.3389\/fcimb.2021.781068","volume":"11","author":"Y Yu","year":"2021","unstructured":"Yu Y, Hu B, Fan H, Zhang H, Lian S, Li H, Li S, Yan X, Wang S, Bai X. Molecular Epidemiology of Extraintestinal Pathogenic Escherichia coli Causing Hemorrhagic Pneumonia in Mink in Northern China. Front Cell Infect Microbiol. 2021;11:781068.","journal-title":"Front Cell Infect Microbiol"},{"issue":"7","key":"4817_CR20","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1128\/AAC.47.7.2161-2168.2003","volume":"47","author":"JR Johnson","year":"2003","unstructured":"Johnson JR, Murray AC, Gajewski A, Sullivan M, Snippes P, Kuskowski MA, Smith KE. Isolation and molecular characterization of nalidixic acid-resistant extraintestinal pathogenic Escherichia coli from retail chicken products. Antimicrob Agents Chemother. 2003;47(7):2161\u20138.","journal-title":"Antimicrob Agents Chemother"},{"issue":"10","key":"4817_CR21","doi-asserted-by":"publisher","first-page":"4555","DOI":"10.1128\/AEM.66.10.4555-4558.2000","volume":"66","author":"O Clermont","year":"2000","unstructured":"Clermont O, Bonacorsi S, Bingen E. Rapid and simple determination of the Escherichia coli phylogenetic group. Appl Environ Microbiol. 2000;66(10):4555\u20138.","journal-title":"Appl Environ Microbiol"},{"issue":"5","key":"4817_CR22","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1111\/j.1365-2958.2006.05172.x","volume":"60","author":"T Wirth","year":"2006","unstructured":"Wirth T, Falush D, Lan RT, Colles F, Mensa P, Wieler LH, Karch H, Reeves PR, Maiden MCJ, Ochman H, et al. Sex and virulence in Escherichia coli: an evolutionary perspective. Mol Microbiol. 2006;60(5):1136\u201351.","journal-title":"Mol Microbiol"},{"issue":"3\u20134","key":"4817_CR23","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.vetmic.2011.11.017","volume":"156","author":"Z Paddock","year":"2012","unstructured":"Paddock Z, Shi XR, Bai JF, Nagaraja TG. Applicability of a multiplex PCR to detect O26, O45, O103, O111, O121, O145, and O157 serogroups of Escherichia coli in cattle feces. Vet Microbiol. 2012;156(3\u20134):381\u20138.","journal-title":"Vet Microbiol"},{"issue":"3","key":"4817_CR24","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1128\/AEM.70.3.1830-1832.2004","volume":"70","author":"C DebRoy","year":"2004","unstructured":"DebRoy C, Roberts E, Kundrat J, Davis MA, Briggs CE, Fratamico PM. Detection of Escherichia coli serogroups O26 and O113 by PCR amplification of the wzx and wzy genes. Appl Environ Microbiol. 2004;70(3):1830\u20132.","journal-title":"Appl Environ Microbiol"},{"issue":"1\u20132","key":"4817_CR25","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/S0014-5793(03)00980-3","volume":"553","author":"J Shao","year":"2003","unstructured":"Shao J, Li M, Jia Q, Lu YQ, Wang PG. Sequence of Escherichia coli O128 antigen biosynthesis cluster and functional identification of an \u03b1-1,2-fucosyltransferase. FEBS Lett. 2003;553(1\u20132):99\u2013103.","journal-title":"FEBS Lett"},{"key":"4817_CR26","first-page":"75","volume":"7","author":"IV Golubeva","year":"1981","unstructured":"Golubeva IV, Andronova NI, Kiseleva BS, Ulisko IN, Nauman G. Serologic groups of O-antigens of E. coli isolated from urinary tract infections within the boundaries of the USSR and East Germany. Zh Mikrobiol Epidemiol Immunobiol. 1981;7:75\u20138.","journal-title":"Zh Mikrobiol Epidemiol Immunobiol."},{"issue":"5","key":"4817_CR27","first-page":"6","volume":"9","author":"SH Wang","year":"2014","unstructured":"Wang SH, Meng QM, Dai JJ, Han XG, Han Y, Ding C, Liu HW, Yu SQ. Development of an Allele-Specific PCR Assay for Simultaneous Sero-Typing of Avian Pathogenic Escherichia coli Predominant O1, O2, O18 and O78 Strains. PLoS One. 2014;9(5):6.","journal-title":"PLoS One"},{"key":"4817_CR28","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3389\/fmicb.2012.00009","volume":"3","author":"JD Pitout","year":"2012","unstructured":"Pitout JD. Extraintestinal pathogenic Escherichia coli: a combination of virulence with antibiotic resistance. Front Microbiol. 2012;3:9.","journal-title":"Front Microbiol"},{"issue":"2","key":"4817_CR29","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1051\/vetres:2004057","volume":"36","author":"KE Rodriguez-Siek","year":"2005","unstructured":"Rodriguez-Siek KE, Giddings CW, Doetkott C, Johnson TJ, Nolan LK. Characterizing the APEC pathotype. Vet Res. 2005;36(2):241\u201356.","journal-title":"Vet Res"},{"issue":"1","key":"4817_CR30","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1086\/315217","volume":"181","author":"JR Johnson","year":"2000","unstructured":"Johnson JR, Stell AL. Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. J Infect Dis. 2000;181(1):261\u201372.","journal-title":"J Infect Dis"},{"issue":"8","key":"4817_CR31","doi-asserted-by":"publisher","first-page":"939","DOI":"10.14202\/vetworld.2017.939-945","volume":"10","author":"FA Bessone","year":"2017","unstructured":"Bessone FA, Bessone G, Marini S, Conde MB, Alustiza FE, Zielinski G. Presence and characterization of Escherichia coli virulence genes isolated from diseased pigs in the central region of Argentina. Veterinary world. 2017;10(8):939\u201345.","journal-title":"Veterinary world"},{"issue":"16","key":"4817_CR32","doi-asserted-by":"publisher","first-page":"3785","DOI":"10.1016\/j.watres.2006.12.026","volume":"41","author":"W Ahmed","year":"2007","unstructured":"Ahmed W, Tucker J, Bettelheim KA, Neller R, Katouli M. Detection of virulence genes in Escherichia coli of an existing metabolic fingerprint database to predict the sources of pathogenic E. coli in surface waters. Water research. 2007;41(16):3785\u201391.","journal-title":"Water research"},{"issue":"4","key":"4817_CR33","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1007\/s00580-010-1122-2","volume":"21","author":"Z Shams","year":"2012","unstructured":"Shams Z, Tahamtan Y, Pourbakhsh A, Hosseiny MH, Kargar M, Hayati M. Detection of enterotoxigenic K99 (F5) and F41 from fecal sample of calves by molecular and serological methods. Comp Clin Pathol. 2012;21(4):475\u20138.","journal-title":"Comp Clin Pathol"},{"issue":"2","key":"4817_CR34","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1128\/IAI.66.2.480-485.1998","volume":"66","author":"S Schubert","year":"1998","unstructured":"Schubert S, Rakin A, Karch H, Carniel E, Heesemann J. Prevalence of the \u201chigh-pathogenicity island\u201d of Yersinia species among Escherichia coli strains that are pathogenic to humans. Infect Immun. 1998;66(2):480\u20135.","journal-title":"Infect Immun"},{"issue":"3","key":"4817_CR35","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.ijmm.2007.01.003","volume":"297","author":"C Ewers","year":"2007","unstructured":"Ewers C, Li GW, Wilking H, Kiessling S, Alt K, Ant\u00e1o EM, Laturnus C, Diehl I, Glodde S, Homeier T, et al. Avian pathogenic, uropathogenic, and newborn meningitis-causing Escherichia coli: How closely related are they? Int J Med Microbiol. 2007;297(3):163\u201376.","journal-title":"Int J Med Microbiol"},{"issue":"9","key":"4817_CR36","doi-asserted-by":"publisher","first-page":"4285","DOI":"10.1128\/JCM.41.9.4285-4291.2003","volume":"41","author":"I T\u00f3th","year":"2003","unstructured":"T\u00f3th I, H\u00e9rault F, Beutin L, Oswald E. Production of cytolethal distending toxins by pathogenic Escherichia coli strains isolated from human and animal sources: establishment of the existence of a new cdt variant (Type IV). J Clin Microbiol. 2003;41(9):4285\u201391.","journal-title":"J Clin Microbiol"},{"issue":"8","key":"4817_CR37","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1128\/AAC.00179-17","volume":"61","author":"Y Matsumura","year":"2017","unstructured":"Matsumura Y, Pitout JDD, Peirano G, DeVinney R, Noguchi T, Yamamoto M, Gomi R, Matsuda T, Nakano S, Nagao M, et al. Rapid Identification of Different Escherichia coli Sequence Type 131 Clades. Antimicrob Agents Chemother. 2017;61(8):9.","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"4817_CR38","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1007\/s00284-013-0470-y","volume":"68","author":"XL Wang","year":"2014","unstructured":"Wang XL, Wang JQ, Hao HF, Qiu L, Liu HJ, Chen SL, Dang RY, Yang ZQ. Pathogenic providencia alcalifaciens strain that causes fatal hemorrhagic pneumonia in piglets. Curr Microbiol. 2014;68(3):278\u201384.","journal-title":"Curr Microbiol"},{"issue":"5","key":"4817_CR39","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1128\/AEM.02983-15","volume":"82","author":"P Vogeleer","year":"2015","unstructured":"Vogeleer P, Tremblay YDN, Jubelin G, Jacques M, Harel J. Biofilm-forming abilities of shiga toxin-producing Escherichia coli isolates associated with human infections. Appl Environ Microbiol. 2015;82(5):1448\u201358.","journal-title":"Appl Environ Microbiol"},{"issue":"12","key":"4817_CR40","first-page":"000721","volume":"7","author":"D Li","year":"2021","unstructured":"Li D, Wyrsch ER, Elankumaran P, Dolejska M, Marenda MS, Browning GF, Bushell RN, McKinnon J, Chowdhury PR, Hitchick N, et al. Genomic comparisons of Escherichia coli ST131 from Australia. Microb Genom. 2021;7(12):000721.","journal-title":"Microb Genom"},{"issue":"8","key":"4817_CR41","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.3201\/eid2608.191724","volume":"26","author":"ABS Saidenberg","year":"2020","unstructured":"Saidenberg ABS, Stegger M, Price LB, Johannesen TB, Aziz M, Cunha MPV, Moreno AM, Kn\u00f6bl T. mcr-Positive Escherichia coli ST131-H22 from Poultry in Brazil. Emerg Infect Dis. 2020;26(8):1951\u20134.","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"4817_CR42","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1111\/zph.13199","volume":"72","author":"W Dewasmika","year":"2025","unstructured":"Dewasmika W, Dissanayake DRA, Neelawala N, Dissanayake BGN, Prasada DVP, Francis VR, Octavia S, Lan R. High occurrence of ST131 among extraintestinal pathogenic Escherichia coli in humans and dogs in Sri Lanka. Zoonoses Public Health. 2025;72(2):200\u20136.","journal-title":"Zoonoses Public Health"},{"issue":"7","key":"4817_CR43","doi-asserted-by":"publisher","first-page":"e00382","DOI":"10.1128\/AAC.00382-19","volume":"63","author":"A Birgy","year":"2019","unstructured":"Birgy A, Levy C, Nicolas-Chanoine MH, Cointe A, Hobson CA, Magnan M, Bechet S, Bidet P, Cohen R, Bonacorsi S. Independent Host Factors and Bacterial Genetic Determinants of the Emergence and Dominance of Escherichia coli Sequence Type 131 CTX-M-27 in a Community Pediatric Cohort Study. Antimicrob Agents Chemother. 2019;63(7):e00382.","journal-title":"Antimicrob Agents Chemother"},{"issue":"8","key":"4817_CR44","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/j.1863-2378.2007.01067.x","volume":"54","author":"R Sura","year":"2007","unstructured":"Sura R, Van Kruiningen HJ, DebRoy C, Hinckley LS, Greenberg KJ, Gordon Z, French RA. Extraintestinal pathogenic Escherichia coli induced acute necrotizing pneumonia in cats. Zoonoses Public Health. 2007;54(8):307\u201313.","journal-title":"Zoonoses Public Health"},{"issue":"3","key":"4817_CR45","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1038\/nrmicro2298","volume":"8","author":"O Tenaillon","year":"2010","unstructured":"Tenaillon O, Skurnik D, Picard B, Denamur E. The population genetics of commensal Escherichia coli. Nat Rev Microbiol. 2010;8(3):207\u201317.","journal-title":"Nat Rev Microbiol"},{"issue":"5","key":"4817_CR46","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/S1286-4579(03)00049-2","volume":"5","author":"TA Russo","year":"2003","unstructured":"Russo TA, Johnson JR. Medical and economic impact of extraintestinal infections due to Escherichia coli: focus on an increasingly important endemic problem. Microbes Infect. 2003;5(5):449\u201356.","journal-title":"Microbes Infect"},{"issue":"2","key":"4817_CR47","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1089\/fpd.2007.0087","volume":"4","author":"JL Smith","year":"2007","unstructured":"Smith JL, Fratamico PM, Gunther NW. Extraintestinal pathogenic Escherichia coli. Foodborne Pathog Dis. 2007;4(2):134\u201363.","journal-title":"Foodborne Pathog Dis"},{"issue":"4","key":"4817_CR48","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1099\/00222615-30-4-295","volume":"30","author":"DA Devine","year":"1989","unstructured":"Devine DA, Robinson L, Roberts AP. Occurrence of K1, K5 and O antigens in Escherichia coli isolates from patients with urinary tract infections or bacteraemia. J Med Microbiol. 1989;30(4):295\u20139.","journal-title":"J Med Microbiol"},{"issue":"3","key":"4817_CR49","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1097\/INF.0b013e3181fab1e7","volume":"30","author":"J Gaschignard","year":"2011","unstructured":"Gaschignard J, Levy C, Romain O, Cohen R, Bingen E, Aujard Y, Boileau P. Neonatal bacterial meningitis: 444 cases in 7 years. Pediatr Infect Dis J. 2011;30(3):212\u20137.","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"4817_CR50","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/nrmicro818","volume":"2","author":"JB Kaper","year":"2004","unstructured":"Kaper JB, Nataro JP, Mobley HLT. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004;2(2):123\u201340.","journal-title":"Nat Rev Microbiol"},{"issue":"4","key":"4817_CR51","first-page":"256","volume":"82","author":"YD Zhao","year":"2018","unstructured":"Zhao YD, Guo LL, Li J, Fang B, Huang XF. Molecular epidemiology, antimicrobial susceptibility, and pulsed-field gel electrophoresis genotyping of Pseudomonas aeruginosa isolates from mink. Can J Vet Res. 2018;82(4):256\u201363.","journal-title":"Can J Vet Res"},{"issue":"5","key":"4817_CR52","doi-asserted-by":"publisher","first-page":"e01596","DOI":"10.1128\/mBio.01596-17","volume":"8","author":"S Shaik","year":"2017","unstructured":"Shaik S, Ranjan A, Tiwari SK, Hussain A, Nandanwar N, Kumar N, Jadhav S, Semmler T, Baddam R, Islam MA, et al. Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages. mBio. 2017;8(5):e01596-17.","journal-title":"mBio"},{"issue":"1","key":"4817_CR53","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1038\/s41467-024-45608-1","volume":"15","author":"RT White","year":"2024","unstructured":"White RT, Bull MJ, Barker CR, Arnott JM, Wootton M, Jones LS, Howe RA, Morgan M, Ashcroft MM, Forde BM, et al. Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales. Nat Commun. 2024;15(1):1371.","journal-title":"Nat Commun"},{"key":"4817_CR54","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1038\/s41429-024-00704-8","volume":"77","author":"NA Hassuna","year":"2024","unstructured":"Hassuna NA, Rabea EM, Mahdi WKM, Abdelraheem WM. Biofilm formation and antimicrobial resistance pattern of uropathogenic E. coli ST131 isolated from children with malignant tumors. J Antibiot (Tokyo). 2024;77:324.","journal-title":"J Antibiot (Tokyo)"},{"issue":"7","key":"4817_CR55","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1099\/mgen.0.000278","volume":"5","author":"K Kikuchi","year":"2019","unstructured":"Kikuchi K, Lee K, Ueno H, Tomari K, Kobori S, Kaetsu A, Matsui M, Suzuki S, Sekizuka T, Kuroda M, et al. Enterohaemorrhagic Escherichia coli O121:H19 acquired an extended-spectrum \u03b2-lactamase gene during the development of an outbreak in two nurseries. Microb Genomics. 2019;5(7):11.","journal-title":"Microb Genomics"},{"issue":"12","key":"4817_CR56","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1086\/509573","volume":"43","author":"KE Johnson","year":"2006","unstructured":"Johnson KE, Thorpe CM, Sears CL. The emerging clinical importance of non-O157 Shiga toxin-producing Escherichia coli. Clin Infect Dis. 2006;43(12):1587\u201395.","journal-title":"Clin Infect Dis"},{"issue":"2","key":"4817_CR57","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1093\/jac\/dkm464","volume":"61","author":"MH Nicolas-Chanoine","year":"2008","unstructured":"Nicolas-Chanoine MH, Blanco J, Leflon-Guibout V, Demarty R, Alonso MP, Cani\u00e7a MM, Park YJ, Lavigne JP, Pitout J, Johnson JR. Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15. J Antimicrob Chemother. 2008;61(2):273\u201381.","journal-title":"J Antimicrob Chemother"},{"issue":"3","key":"4817_CR58","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1128\/CMR.00125-13","volume":"27","author":"MH Nicolas-Chanoine","year":"2014","unstructured":"Nicolas-Chanoine MH, Bertrand X, Madec JY. Escherichia coli ST131, an intriguing clonal group. Clin Microbiol Rev. 2014;27(3):543\u201374.","journal-title":"Clin Microbiol Rev"},{"issue":"9","key":"4817_CR59","doi-asserted-by":"publisher","first-page":"4997","DOI":"10.1128\/AAC.02824-14","volume":"58","author":"R Banerjee","year":"2014","unstructured":"Banerjee R, Johnson JR. A new clone sweeps clean: the enigmatic emergence of Escherichia coli sequence type 131. Antimicrob Agents Chemother. 2014;58(9):4997\u20135004.","journal-title":"Antimicrob Agents Chemother"},{"issue":"6","key":"4817_CR60","doi-asserted-by":"publisher","first-page":"O344","DOI":"10.1111\/1469-0691.12413","volume":"20","author":"A Brolund","year":"2014","unstructured":"Brolund A, Edquist PJ, M\u00e4kitalo B, Olsson-Liljequist B, S\u00f6derblom T, Wisell KT, Giske CG. Epidemiology of extended-spectrum \u03b2-lactamase-producing Escherichia coli in Sweden 2007\u20132011. Clin Microbiol Infect. 2014;20(6):O344-352.","journal-title":"Clin Microbiol Infect"},{"key":"4817_CR61","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/bs.aambs.2014.09.002","volume":"90","author":"AJ Mathers","year":"2015","unstructured":"Mathers AJ, Peirano G, Pitout JD. Escherichia coli ST131: The quintessential example of an international multiresistant high-risk clone. Adv Appl Microbiol. 2015;90:109\u201354.","journal-title":"Adv Appl Microbiol"},{"issue":"1","key":"4817_CR62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/jac\/dkq415","volume":"66","author":"BA Rogers","year":"2011","unstructured":"Rogers BA, Sidjabat HE, Paterson DL. Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain. J Antimicrob Chemother. 2011;66(1):1\u201314.","journal-title":"J Antimicrob Chemother"},{"issue":"26","key":"4817_CR63","doi-asserted-by":"publisher","first-page":"705","DOI":"10.15585\/mmwr.mm6626a6","volume":"66","author":"V Morton","year":"2017","unstructured":"Morton V, Cheng JM, Sharma D, Kearney A. An outbreak of shiga toxin-producingEscherichia coli O121 infections associated with flour - Canada, 2016\u20132017. MMWR-Morb Mortal Wkly Rep. 2017;66(26):705\u20136.","journal-title":"MMWR-Morb Mortal Wkly Rep"},{"issue":"21","key":"4817_CR64","doi-asserted-by":"publisher","first-page":"2036","DOI":"10.1056\/NEJMoa1615910","volume":"377","author":"SJ Crowe","year":"2017","unstructured":"Crowe SJ, Bottichio L, Shade LN, Whitney BM, Corral N, Melius B, Arends KD, Donovan D, Stone J, Allen K, et al. Shiga toxin-producing E. coli infections associated with flour. N Engl J Med. 2017;377(21):2036\u201343.","journal-title":"N Engl J Med"},{"issue":"2","key":"4817_CR65","doi-asserted-by":"publisher","first-page":"11","DOI":"10.14745\/ccdr.v47i01a03","volume":"47","author":"E Boyd","year":"2021","unstructured":"Boyd E, Trmcic A, Taylor M, Shyng S, Hasselback P, Man S, Tchao C, Stone J, Janz L, Hoang L, et al. Escherichia coli O121 outbreak associated with raw milk Gouda-like cheese in British Columbia, Canada, 2018. Can Commun Dis Rep. 2021;47(2):11\u20136.","journal-title":"Can Commun Dis Rep"},{"issue":"2","key":"4817_CR66","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.ijfoodmicro.2012.08.008","volume":"162","author":"C Farrokh","year":"2013","unstructured":"Farrokh C, Jordan K, Auvray F, Glass K, Oppegaard H, Raynaud S, Thevenot D, Condron R, De Reu K, Govaris A, et al. Review of Shiga-toxin-producing Escherichia coli (STEC) and their significance in dairy production. Int J Food Microbiol. 2013;162(2):190\u2013212.","journal-title":"Int J Food Microbiol"},{"key":"4817_CR67","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.ijfoodmicro.2015.01.018","volume":"200","author":"XN Bai","year":"2015","unstructured":"Bai XN, Wang H, Xin YQ, Wei RJ, Tang XY, Zhao AL, Sun H, Zhang W, Wang Y, Xu YM, et al. Prevalence and characteristics of Shiga toxin-producing Escherichia coli isolated from retail raw meats in China. Int J Food Microbiol. 2015;200:31\u20138.","journal-title":"Int J Food Microbiol"},{"issue":"3","key":"4817_CR68","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1086\/600302","volume":"49","author":"EB Hedican","year":"2009","unstructured":"Hedican EB, Medus C, Besser JM, Juni BA, Koziol B, Taylor C, Smith KE. Characteristics of O157 versus non-O157 Shiga toxin-producing Escherichia coli infections in Minnesota, 2000\u20132006. Clin Infect Dis. 2009;49(3):358\u201364.","journal-title":"Clin Infect Dis"},{"issue":"18","key":"4817_CR69","doi-asserted-by":"publisher","first-page":"6689","DOI":"10.1128\/AEM.01259-12","volume":"78","author":"KN Norman","year":"2012","unstructured":"Norman KN, Strockbine NA, Bono JL. Association of nucleotide polymorphisms within the O-antigen gene cluster of Escherichia coli O26, O45, O103, O111, O121, and O145 with serogroups and genetic subtypes. Appl Environ Microbiol. 2012;78(18):6689\u2013703.","journal-title":"Appl Environ Microbiol"},{"issue":"3","key":"4817_CR70","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1371\/journal.pone.0034294","volume":"7","author":"JP Lavigne","year":"2012","unstructured":"Lavigne JP, Vergunst AC, Goret L, Sotto A, Combescure C, Blanco J, O\u2019Callaghan D, Nicolas-Chanoine MH. Virulence potential and genomic mapping of the worldwide clone Escherichia coli ST131. PLoS One. 2012;7(3):10.","journal-title":"PLoS One"},{"key":"4817_CR71","first-page":"100518","volume":"16","author":"CM Liu","year":"2023","unstructured":"Liu CM, Aziz M, Park DE, Wu Z, Stegger M, Li M, Wang Y, Schmidlin K, Johnson TJ, Koch BJ, et al. Using source-associated mobile genetic elements to identify zoonotic extraintestinal E. coli infections. One Health (Amsterdam, Netherlands). 2023;16:100518.","journal-title":"One Health (Amsterdam, Netherlands)"}],"container-title":["BMC Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-025-04817-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12917-025-04817-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-025-04817-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T10:01:57Z","timestamp":1748340117000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-025-04817-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,27]]},"references-count":71,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4817"],"URL":"https:\/\/doi.org\/10.1186\/s12917-025-04817-6","relation":{},"ISSN":["1746-6148"],"issn-type":[{"value":"1746-6148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,27]]},"assertion":[{"value":"24 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Ethical Committee of the Institute approved all scientific experiments. All applicable international and national guidelines for the care and use of animals in experiments were followed and approved by the Institutional Committee of Northeast Agricultural University (NEAUEC20200338, 3 April 2020). We also obtained permission from the farmers to use the disease animals in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"378"}}