{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T02:19:34Z","timestamp":1779416374351,"version":"3.53.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":42,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Tianzhong Scholars Program of Huanghuai University"},{"name":"Ningxia Hui Autonomous Region Agricultural Science and Technology Independent Innovation Fund Project","award":["NKYG-25-03"],"award-info":[{"award-number":["NKYG-25-03"]}]},{"name":"Ningxia Hui Autonomous Region Science and Technology Infrastructure Construction Project","award":["2025DPC05017"],"award-info":[{"award-number":["2025DPC05017"]}]},{"name":"the Science and Technology Development Plan Project of Henan Province of China","award":["262102111010"],"award-info":[{"award-number":["262102111010"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Vet Res"],"DOI":"10.1186\/s12917-026-05453-4","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T01:15:53Z","timestamp":1775783753000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Overexpression of the ncd2 gene in Sphingomonas sp. Z392 improves the gut health and meat quality of broiler chickens"],"prefix":"10.1186","volume":"22","author":[{"given":"Gailing","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengqin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwen","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoying","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aizhen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingcheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"key":"5453_CR1","doi-asserted-by":"publisher","first-page":"0","DOI":"10.1099\/ijsem.0.006572","volume":"74","author":"EJ Kim","year":"2024","unstructured":"Kim EJ, Maeng SH, Kim MK. Sphingomonas longa sp. nov., Sphingomonas mollis sp. nov. and Sphingomonas aurea sp. nov.: three novel Sphingomonas species isolated from soil. Int J Syst Evol Microbiol. 2024;74:0.","journal-title":"Int J Syst Evol Microbiol"},{"key":"5453_CR2","first-page":"65","volume":"12","author":"MC Wang","year":"2021","unstructured":"Wang MC, Wang Y, Wang GL, Xu LL, Li E. Isolation and identification of Sphingomonas sp. from chicken cecum and its ammonia-degrading activity. J Biotech Res. 2021;12:65\u201373.","journal-title":"J Biotech Res"},{"key":"5453_CR3","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.3390\/polym14091920","volume":"14","author":"H Huang","year":"2022","unstructured":"Huang H, Lin J, Wang W, Li S. Biopolymers Produced by Sphingomonas Strains and Their Potential Applications in Petroleum Production. Polym (Basel). 2022;14:1920.","journal-title":"Polym (Basel)"},{"key":"5453_CR4","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.3390\/ani14131920","volume":"14","author":"MC Wang","year":"2024","unstructured":"Wang MC, Zhong J, Guo YN, Zhao SQ, Xia HL, Wang GL, Liu CY, Guo AZ. Effects of Adding Sphingomonas Z392 to Drinking Water on Growth Performance, Intestinal Histological Structure, and Microbial Community of Broiler Chickens. Animals. 2024;14:1920.","journal-title":"Animals"},{"key":"5453_CR5","doi-asserted-by":"publisher","first-page":"124253","DOI":"10.1016\/j.jhazmat.2020.124253","volume":"405","author":"B Zhang","year":"2021","unstructured":"Zhang B, Sun L, Song X, Huang D, Li M, Peng C, Wang W. Genetically engineered thermotolerant facultative anaerobes for high-efficient degradation of multiple hazardous nitroalkanes. J Hazard Mater. 2021;405:124253.","journal-title":"J Hazard Mater"},{"key":"5453_CR6","doi-asserted-by":"publisher","first-page":"1437056","DOI":"10.3389\/fmicb.2024.1437056","volume":"15","author":"MC Wang","year":"2025","unstructured":"Wang MC, Liu DQ, Xia HL, Wang GL, Liu CY, Guo YN, Guo A. Z. Multiomics-based analysis of the mechanism of ammonia reduction In Sphingomonas. Front Microbiol. 2025;15:1437056.","journal-title":"Front Microbiol"},{"key":"5453_CR7","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.abb.2012.03.015","volume":"521","author":"K Francis","year":"2012","unstructured":"Francis K, Nishino SF, Spain JC, Gadda G. A novel activity for fungal nitronate monooxygenase: Detoxification of the metabolic inhibitor propionate-3-nitronate. Arch Biochem Biophys. 2012;521:84\u20139.","journal-title":"Arch Biochem Biophys"},{"key":"5453_CR8","first-page":"142","volume":"13","author":"MC Wang","year":"2022","unstructured":"Wang MC, Tang JZ, Wang GL, Guo YN, Guo L, Li EZ. Isolation and identification of an acid-tolerant Lactobacillus species from chicken intestine and its application. J Biotech Res. 2022;13:142\u201351.","journal-title":"J Biotech Res"},{"key":"5453_CR9","doi-asserted-by":"publisher","first-page":"103556","DOI":"10.1016\/j.psj.2024.103556","volume":"103","author":"R Budiarto","year":"2024","unstructured":"Budiarto R, Ujilestari T, Rumhayati B, Adli DN, Hudaya MF, Sitaresmi PI, Widodo S, Wulandari W, Wahyono T, Sholikin M. M. Meta-analysis of citrus-derived additives on chicken meat quality and safety: a comprehensive evaluation of acceptability, physicochemical properties, and microbial contamination. Poult Sci. 2024;103:103556.","journal-title":"Poult Sci"},{"key":"5453_CR10","doi-asserted-by":"publisher","first-page":"104666","DOI":"10.1016\/j.psj.2024.104666","volume":"104","author":"X Yang","year":"2025","unstructured":"Yang X, Cai B, Zhang Z, Mo Y, Zhou Z, Wu R, Kong S, Cai D, Zhang R, Li Z, Nie Q. Exploring variances in meat quality between Qingyuan partridge chicken and Cobb broiler: Insights from combined multi-omics analysis. Poult Sci. 2025;104:104666.","journal-title":"Poult Sci"},{"key":"5453_CR11","doi-asserted-by":"publisher","first-page":"102168","DOI":"10.1016\/j.psj.2022.102168","volume":"101","author":"S Deng","year":"2022","unstructured":"Deng S, Liu R, Li C, Xu X, Zhou G. Meat quality and flavor compounds of soft-boiled chickens: effect of Chinese yellow-feathered chicken breed and slaughter age. Poult Sci. 2022;101:102168.","journal-title":"Poult Sci"},{"key":"5453_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12602-020-09640-z","volume":"13","author":"DP Neveling","year":"2021","unstructured":"Neveling DP, Dicks LMT, Probiotics. An antibiotic replacement strategy for healthy broilers and productive rearing. Probiotics Antimicrob Proteins. 2021;13:1\u201311.","journal-title":"Probiotics Antimicrob Proteins"},{"key":"5453_CR13","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.vetmic.2012.03.032","volume":"159","author":"D Stanley","year":"2012","unstructured":"Stanley D, Keyburn AL, Denman SE, Moore RJ. Changes in the caecal microflora of chickens following Clostridium perfringens challenge to induce necrotic enteritis. Vet Microbiol. 2012;159:155\u201362.","journal-title":"Vet Microbiol"},{"key":"5453_CR14","doi-asserted-by":"publisher","first-page":"681","DOI":"10.3390\/v11080681","volume":"11","author":"M Abaidullah","year":"2019","unstructured":"Abaidullah M, Peng S, Kamran M, Song X, Yin Z. Current findings on gut microbiota mediated immune modulation against viral diseases in chicken. Viruses. 2019;11:681\u201395.","journal-title":"Viruses"},{"key":"5453_CR15","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1186\/s13568-020-01153-w","volume":"10","author":"DS Rajput","year":"2020","unstructured":"Rajput DS, Zeng D, Khalique A, Rajput SS, Wang H, Zhao Y, Sun N. Ni X. Pretreatment with probiotics ameliorate gut health and necrotic enteritis in broiler chickens, a substitute to antibiotics. AMB Express. 2020;10:220.","journal-title":"AMB Express"},{"key":"5453_CR16","doi-asserted-by":"publisher","first-page":"103206","DOI":"10.1016\/j.psj.2023.103206","volume":"103","author":"SA El-Shobokshy","year":"2024","unstructured":"El-Shobokshy SA, Abo-Samaha MI, Khafaga AF, Fakiha KG, Khatab SA, Abdelmaksoud EM, Khalek Soltan MA, Othman SI, Rudayni HA, Allam AA, Emam M. The beneficial effect of nanomethionine supplementation on growth performance, gene expression profile, and histopathology of heat-stressed broiler chicken. Poult Sci. 2024;103:103206.","journal-title":"Poult Sci"},{"key":"5453_CR17","first-page":"3085","volume":"12","author":"C Bao","year":"2022","unstructured":"Bao C, Zhang W, Wang J, Liu Y, Cao H, Li F, Liu S, Shang Z, Cao Y, Dong B. The Effects of Dietary Bacillus amyloliquefaciens TL106 Supplementation, as an Alternative to Antibiotics, on Growth Performance, Intestinal Immunity, Epithelial Barrier Integrity, and Intestinal Microbiota in Broilers. Anim (Basel). 2022;12:3085.","journal-title":"Anim (Basel)"},{"key":"5453_CR18","doi-asserted-by":"publisher","first-page":"852545","DOI":"10.3389\/fvets.2022.852545","volume":"9","author":"L Chang","year":"2022","unstructured":"Chang L, Ding Y, Wang Y, Song Z, Li F, He X, Zhang H. Effects of Different Oligosaccharides on Growth Performance and Intestinal Function in Broilers. Front Vet Sci. 2022;9:852545.","journal-title":"Front Vet Sci"},{"key":"5453_CR19","doi-asserted-by":"publisher","first-page":"1107798","DOI":"10.3389\/fvets.2023.1107798","volume":"10","author":"Z Li","year":"2023","unstructured":"Li Z, Long L, Jin X, Li Y, Wu Q, Chen X, Geng Z, Zhang C. Effects of Clostridium butyricum on growth performance, meat quality, and intestinal health of broilers. Front Vet Sci. 2023;10:1107798.","journal-title":"Front Vet Sci"},{"key":"5453_CR20","doi-asserted-by":"publisher","first-page":"106317","DOI":"10.1016\/j.pestbp.2025.106317","volume":"208","author":"H Zhang","year":"2025","unstructured":"Zhang H, Wang XY, Sun TF, Chen TJ, Ding JL, Feng MG, Ying S. H. A family of nitronate monooxygenase-domain proteins are essential for biocontrol potential of the insect mycopathogen Beauveria bassiana. Pestic Biochem Physiol. 2025;208:106317.","journal-title":"Pestic Biochem Physiol"},{"key":"5453_CR21","doi-asserted-by":"publisher","first-page":"8019","DOI":"10.1007\/s00253-021-11623-1","volume":"105","author":"JC Torres-Guzman","year":"2021","unstructured":"Torres-Guzman JC, Padilla-Guerrero IE, Cervantes-Quintero KY, et al. Peculiarities of nitronate monooxygenases and perspectives for in vivo and in vitro applications. Appl Microbiol Biotechnol. 2021;105:8019\u201332.","journal-title":"Appl Microbiol Biotechnol"},{"key":"5453_CR22","doi-asserted-by":"publisher","first-page":"2997","DOI":"10.1007\/s13197-017-2789-z","volume":"54","author":"NA Mir","year":"2017","unstructured":"Mir NA, Rafiq A, Kumar F, Singh V, Shukla V. Determinants of broiler chicken meat quality and factors affecting them: a review. J Food Sci Technol. 2017;54:2997\u20133009.","journal-title":"J Food Sci Technol"},{"key":"5453_CR23","first-page":"101330","volume-title":"Dietary effect of Dendrobium officinale leaves on chicken meat quality, fatty acid composition, and volatile compounds profile","author":"W Zhao","year":"2024","unstructured":"Zhao W, Tian Y, Wang Y, Du J, Chen L, Gu T, Song M, Lu L, Sun C. Dietary effect of Dendrobium officinale leaves on chicken meat quality, fatty acid composition, and volatile compounds profile. Volume 22. Food Chemistry: X; 2024. p. 101330."},{"key":"5453_CR24","doi-asserted-by":"publisher","first-page":"101793","DOI":"10.1016\/j.psj.2022.101793","volume":"101","author":"T Kang","year":"2022","unstructured":"Kang T, Yim D, Kim SS, Baek KH, Kim HJ, Jo C. Effect of plasma-activated acetic acid on inactivation of Salmonella Typhimurium and quality traits on chicken meats. Poult Sci. 2022;101:101793.","journal-title":"Poult Sci"},{"key":"5453_CR25","doi-asserted-by":"publisher","first-page":"102631","DOI":"10.1016\/j.psj.2023.102631","volume":"102","author":"E Sosn\u00f3wka-Czajka","year":"2023","unstructured":"Sosn\u00f3wka-Czajka E, Skomorucha I, Obremski K, Wojtacha P. Performance and meat quality of broiler chickens fed with the addition of dried fruit pomace. Poult Sci. 2023;102:102631.","journal-title":"Poult Sci"},{"key":"5453_CR26","doi-asserted-by":"crossref","unstructured":"Herich R, Szab\u00f3ov\u00e1 R, Karaffov\u00e1 V, Racines MP, \u0160efcov\u00e1 MA, Larrea-\u00c1lvarez M. A Narrative Review on the Impact of Probiotic Supplementation on Muscle Development, Metabolic Regulation, and Fiber Traits Related to Meat Quality in Broiler Chickens, Microorganisms. 2025;13:784.","DOI":"10.3390\/microorganisms13040784"},{"key":"5453_CR27","doi-asserted-by":"publisher","first-page":"100906","DOI":"10.1016\/j.psj.2020.11.073","volume":"100","author":"AA Mohammed","year":"2021","unstructured":"Mohammed AA, Zaki RS, Negm EA, Mahmoud MA, Cheng HW. Effects of dietary supplementation of a probiotic (Bacillus subtilis) on bone mass and meat quality of broiler chickens. Poult Sci. 2021;100:100906.","journal-title":"Poult Sci"},{"key":"5453_CR28","doi-asserted-by":"publisher","first-page":"103971","DOI":"10.1016\/j.psj.2024.103971","volume":"103","author":"S Selim","year":"2024","unstructured":"Selim S, Abdel-Megeid NS, Alhotan RA, Ebrahim A, Hussein E. Nutraceuticals vs. antibiotic growth promoters: differential impacts on performance, meat quality, blood lipids, cecal microbiota, and organ histomorphology of broiler chicken. Poult Sci. 2024;103:103971.","journal-title":"Poult Sci"},{"key":"5453_CR29","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.aninu.2020.03.002","volume":"6","author":"K Dev","year":"2020","unstructured":"Dev K, Mir NA, Biswas A, Kannoujia J, Begum J, Kant R, Mandal A. Dietary synbiotic supplementation improves the growth performance, body antioxidant pool, serum biochemistry, meat quality, and lipid oxidative stability in broiler chickens. Anim Nutr. 2020;6:325\u201332.","journal-title":"Anim Nutr"},{"key":"5453_CR30","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s00726-025-03447-4","volume":"57","author":"EM Sadeesh","year":"2025","unstructured":"Sadeesh EM, Lahamge MS. Unveiling the tissue-specific landscape of nuclear-encoded mitochondrial genes involved in amino acid metabolism in buffalo. Amino Acids. 2025;57:17.","journal-title":"Amino Acids"},{"key":"5453_CR31","doi-asserted-by":"publisher","first-page":"5255","DOI":"10.1007\/s11033-023-08416-2","volume":"50","author":"EM Sadeesh","year":"2023","unstructured":"Sadeesh EM, Singla N, Lahamge MS, Kumari S, Ampadi AN, Anuj M. Tissue heterogeneity of mitochondrial activity, biogenesis and mitochondrial protein gene expression in buffalo. Mol Biol Rep. 2023;50:5255\u201366.","journal-title":"Mol Biol Rep"},{"key":"5453_CR32","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1007\/s11033-024-10022-9","volume":"51","author":"EM Sadeesh","year":"2024","unstructured":"Sadeesh EM, Malik A, Lahamge MS, Singh P. Differential expression of nuclear-derived mitochondrial succinate dehydrogenase genes in metabolically active buffalo tissues. Mol Biol Rep. 2024;51:1071.","journal-title":"Mol Biol Rep"},{"key":"5453_CR33","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s12033-024-01085-x","volume":"67","author":"EM Sadeesh","year":"2025","unstructured":"Sadeesh EM, Lahamge MS, Malik A, Ampadi AN. Differential Expression of Nuclear-Encoded Mitochondrial Protein Genes of ATP Synthase Across Different Tissues of Female Buffalo. Mol Biotechnol. 2025;67:705\u201322.","journal-title":"Mol Biotechnol"},{"key":"5453_CR34","doi-asserted-by":"publisher","first-page":"2411","DOI":"10.1007\/s12033-024-01206-6","volume":"67","author":"EM Sadeesh","year":"2025","unstructured":"Sadeesh EM, Lahamge MS, Malik A, Ampadi AN. Nuclear Genome-Encoded Mitochondrial OXPHOS Complex I Genes in Female Buffalo Show Tissue-Specific Differences. Mol Biotechnol. 2025;67:2411\u201327.","journal-title":"Mol Biotechnol"},{"key":"5453_CR35","doi-asserted-by":"publisher","first-page":"e3000411","DOI":"10.1371\/journal.pbio.3000411","volume":"18","author":"NP Du Sert","year":"2020","unstructured":"Du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U. Emerson M. Reporting animal research: explanation and elaboration for the ARRIVE guidelines 2.0. PLoS Biol. 2020;18:e3000411.","journal-title":"PLoS Biol"}],"container-title":["BMC Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12917-026-05453-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-026-05453-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-026-05453-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T01:14:20Z","timestamp":1779412460000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12917-026-05453-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,10]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5453"],"URL":"https:\/\/doi.org\/10.1186\/s12917-026-05453-4","relation":{},"ISSN":["1746-6148"],"issn-type":[{"value":"1746-6148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,10]]},"assertion":[{"value":"24 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The project underwent ethical review and was approved by the Academic Committee of Huanghuai University (Permit number: 202009220005). The care and use of experimental animals complied with local animal welfare laws, guidelines, and policies. The study was also carried out in compliance with the ARRIVE guidelines [\n                      \n                      ]. The owners of the broiler chickens were informed of the research work to be conducted before the experiment began and their consent was obtained. Informed consent was obtained from all the participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"297"}}