{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:05:47Z","timestamp":1784189147549,"version":"3.55.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":55,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Vet Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Sporobolomyces<\/jats:italic>\n                      spp. is a yeast-like fungal organism commonly found in the environment. It has been sporadically reported in human medicine as a potential cause of dermatitis, lymphadenitis, meningitis, and endophthalmitis. In veterinary medicine, this fungus has only been described once in a dog affected with granulomatous meningoencephalitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      A 3-year-old Jagd Terrier was presented with crusted, erosive and ulcerative skin lesions primarily affecting the nose, but also the limbs and tail. A pyogranulomatous dermatitis was identified on skin histopathological sections. Pan-fungal conventional polymerase chain reaction (PCR) performed on skin biopsies yielded a positive result. Subsequent sequencing of the PCR product identified\n                      <jats:italic>Sporobolomyces roseus<\/jats:italic>\n                      with 99.27% sequence identity. Anti-fungal treatment with a combination of voriconazole and terbinafine for two months led to an almost complete resolution of the lesions. For financial reasons, antifungal therapy was discontinued prematurely, leading to a relapse of dermatological lesions. Other anti-fungal treatments were attempted without clinical improvement leading to subsequent euthanasia of the dog.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This case report described dermatological lesions associated with\n                      <jats:italic>Sporobolomyces roseus<\/jats:italic>\n                      in a dog and the challenges associated with anti-fungal treatment.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12917-026-05576-8","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T08:25:39Z","timestamp":1779438339000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pyogranulomatous dermatitis associated with Sporobolomyces roseus in a dog"],"prefix":"10.1186","volume":"22","author":[{"given":"Sarah","family":"Berger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mutien-Marie","family":"Garigliany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Remy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Roels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"issue":"8","key":"5576_CR1","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1001\/archderm.1984.01650440089026","volume":"120","author":"CA Kauffman","year":"1984","unstructured":"Kauffman CA, Bergman AG. Dermatitis due to Sporobolomyces Infection. Arch Dermatol. 1984;120(8):1059\u201360.","journal-title":"Arch Dermatol"},{"issue":"Suppl 3","key":"5576_CR2","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1111\/1469-0691.12360","volume":"20","author":"MC Arendrup","year":"2014","unstructured":"Arendrup MC, Boekhout T, Akova M, Meis JF, Cornely OA, Lortholary O. ESCMID and ECMM joint clinical guidelines for the diagnosis and management of rare invasive yeast infections. Clin Microbiol Infect. 2014;20(Suppl 3):76\u201398.","journal-title":"Clin Microbiol Infect"},{"key":"5576_CR3","doi-asserted-by":"publisher","first-page":"2050313X1984415","DOI":"10.1177\/2050313X19844154","volume":"7","author":"R Damji","year":"2019","unstructured":"Damji R, Mukherji A, Mussani F. Sporobolomyces salmonicolor: A case report of a rare cutaneous fungal infection. SAGE Open Med Case Rep. 2019;7:2050313X19844154. https:\/\/doi.org\/10.1177\/2050313X19844154.","journal-title":"SAGE Open Med Case Rep"},{"key":"5576_CR4","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1038\/sj.eye.6702051","volume":"20","author":"V Sharma","year":"2006","unstructured":"Sharma V, Shankar J, Kotamarthi V. Endogeneous endophthalmitis caused by Sporobolomyces salmonicolor. Eye. 2006;20:945\u20136. https:\/\/doi.org\/10.1038\/sj.eye.6702051.","journal-title":"Eye"},{"key":"5576_CR5","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1097\/00002030-199403000-00015","volume":"8","author":"J Plazas","year":"1994","unstructured":"Plazas J, Portilla J, Boix V, P\u00e9rez-Mateo M. Sporobolomyces salmonicolor lymphadenitis in an AIDS patient: Pathogen or passenger? AIDS. 1994;8:387\u201398.","journal-title":"AIDS"},{"issue":"5","key":"5576_CR6","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1177\/0300985810391110","volume":"48","author":"V Saey","year":"2011","unstructured":"Saey V, Vanhaesebrouck A, Maes S, Simaey LV, Van Ham L, Deschaght P, et al. Granulomatous meningoencephalitis associated with Sporobolomyces roseus in a dog. Vet Pathol. 2011;48(5):1158\u201360.","journal-title":"Vet Pathol"},{"issue":"3","key":"5576_CR7","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1093\/infdis\/164.3.623","volume":"164","author":"JT Morris","year":"1991","unstructured":"Morris JT, Beckius M, McAllister CK. Sporobolomyces infection in an AIDS patient. J Infect Dis. 1991;164(3):623\u20134.","journal-title":"J Infect Dis"},{"key":"5576_CR8","doi-asserted-by":"publisher","unstructured":"Muench TM, White MR, Wu CC. Visceral mycosis in Chinook salmon (Oncorhynchus tschawytscha) due to Sporobolomyces salmonicolor. Vet Pathol. 1996;33(2):238\u2009\u2013\u200941. https:\/\/doi.org\/10.1177\/030098589603300216. PMID: 8801720.","DOI":"10.1177\/030098589603300216"},{"issue":"4","key":"5576_CR9","doi-asserted-by":"publisher","first-page":"1510","DOI":"10.1128\/JCM.38.4.1510-1515.2000","volume":"38","author":"T Henry","year":"2000","unstructured":"Henry T, Iwen PC, Hinrichs SH. Identification of Aspergillus species using internal transcribed spacer regions 1 and 2. J Clin Microbiol. 2000;38(4):1510\u20135.","journal-title":"J Clin Microbiol"},{"key":"5576_CR10","unstructured":"Miller WH Jr, Griffin CE, Campbell KL. Muller & Kirk\u2019s Small Animal Dermatology. 7th ed. St. Louis (MO): Elsevier; 2013. Chapter 4: Bacterial skin diseases; Chap. 5: Fungal skin diseases; Chap. 10: Miscellaneous skin diseases."},{"issue":"1","key":"5576_CR11","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1128\/JCM.36.1.198-202.1998","volume":"36","author":"A Espinel-Ingroff","year":"1998","unstructured":"Espinel-Ingroff A. In vitro activity of the new triazole voriconazole (UK-109,496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens. J Clin Microbiol. 1998;36(1):198\u2013202.","journal-title":"J Clin Microbiol"}],"container-title":["BMC Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12917-026-05576-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-026-05576-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12917-026-05576-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T07:27:46Z","timestamp":1784186866000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12917-026-05576-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5576"],"URL":"https:\/\/doi.org\/10.1186\/s12917-026-05576-8","relation":{},"ISSN":["1746-6148"],"issn-type":[{"value":"1746-6148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,22]]},"assertion":[{"value":"13 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"No unnecessary tests were performed. The owner of this patient gave consent for all the procedures that were carried out. Informed consent was obtained from all participants.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The patient\u2019s owner gave consent for publishing this case report.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"426"}}