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The session explored how the Collaboratory, a WHO digital initiative connecting diverse communities of practice, fosters co-creation, supports the development of collaborative analytical tools, and strengthens the translation of evidence-base into public health action. Through a combination of short presentations and a panel discussion, the session examined key Collaboratory initiatives, including the Global Repository of Epidemiological Parameters (grEPI), AI-enabled pipelines for evidence synthesis, the Epiverse toolkit for outbreak analysis, and semantic search tools to improve the discoverability of epidemiological resources. Discussions addressed challenges of integration into national public health systems, governance models, sustainability, capacity-building, AI reliability, and ethical use. 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