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Point-of-care ultrasound has been shown to be accessible and effective in many aspects of healthcare, including assessing changes in lung pathology. However, few studies have examined self-administered at-home lung ultrasound (SAAH-LUS), in particular performed by non-clinical patients (NCPs).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Research question<\/jats:title>\n                <jats:p>Are NCPs able to perform SAAH-LUS using remote teleguidance and produce interpretable images?<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Study design<\/jats:title>\n                <jats:p>Patients were enrolled to the study in a mix of in-person and virtual recruitment, and shipped a smartphone as well as a point of care ultrasound device. Tele-guidance was provided by a remote physician using software integrated with the point of care ultrasound device, allowing real-time remote visualization and guidance of a patient scanning their own chest. A post-intervention survey was conducted to assess patient satisfaction, feasibility, and acceptability of SAAH-LUS. Two POCUS expert reviewers reviewed the scans for interpretability, and inter-rater agreement between the two reviewers was also computed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Eighteen patients successfully underwent 7\u201314\u00a0days of daily telemedicine in parallel to daily SAAH-LUS. Across 1339 scans obtained from ten different lung zones, the average proportion of interpretability was 96% with a chance-corrected agreement, or Cohen\u2019s kappa, reported as \u03ba\u2009=\u20090.67 (significant agreement). 100% of NCPs surveyed found SAAH-LUS to be a positive experience, particularly for its ease of operation and ability to increase access to healthcare services.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Interpretation<\/jats:title>\n                <jats:p>This study demonstrates that NCPs can obtain interpretable LUS images at home, highlighting the potential for SAAH-LUS to increase diagnostic capacity, particularly for rural and remote regions where complex imaging and healthcare providers are difficult to obtain.<\/jats:p>\n                <jats:p><jats:italic>Trial registration<\/jats:italic> The clinical trials has been registered (clinicaltrials.gov). Registration number: NCT04967729<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12931-024-02744-y","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T13:03:27Z","timestamp":1709643807000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Self-administered at-home lung ultrasound with remote guidance in patients without clinical training"],"prefix":"10.1186","volume":"25","clinical-trial-number":[{"clinical-trial-number":"nct04967729","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Nika","family":"Elmi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Sadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Myslik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Chenkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Cherniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,5]]},"reference":[{"issue":"10315","key":"2744_CR1","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.1016\/S0140-6736(21)00673-5","volume":"398","author":"KA Fleming","year":"2021","unstructured":"Fleming KA, Horton S, Wilson ML, Atun R, DeStigter K, Flanigan J, et al. 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REB approval was obtained from the Markham-Stouffville Hospital REB on January 19, 2021, approval number 114-2005. IRB approval was obtained through Veritas IRB on June 10, 2021, approval number 2711-6311-4 for studies involving humans. Informed consent was obtained from all participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Butterfly iQ had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. Rocket Doctor Inc. funded the research coordinator, shipping costs, and ancillary items. Beyond funding the research team (NE, BC, YS, FE), Rocket Doctor did not play a role in the design of the study, analysis, interpretation of the data, and in writing the manuscript. Rocket Doctor was utilized as the telehealth platform for data collection. The study was run independently and was not influenced in any way by the funding body.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"111"}}