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Local ethics committee approval was obtained for sampling collection (Comitato Etico Azienda Ospedaliero Univeristaria Ferrara, Ferrara, Italy. Ref. number 080399 \u2013 Approved in March 2018). Informed written consent was obtained from each participant.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for"}},{"value":"<b>SB<\/b> has nothing to declare. <b>MB<\/b> has nothing to declare. <b>SC<\/b> has nothing to declare. <b>PC<\/b> has nothing to declare. <b>LDF<\/b> has nothing to declare. <b>MT<\/b> has nothing to declare. <b>FeBa<\/b> has nothing to declare. <b>TB<\/b> has nothing to declare. <b>AMR<\/b> has nothing to declare. <b>FuBr<\/b> declares personal payments for participation on Advisory Board from ASTRAZENECA, BOEHRINGER INGELHEIM, CHIESI, GSK, MENARINI GROUP, SANOFI, P&G; personal payments or honoraria for lectures, presentations from ASTRAZENECA, BOEHRINGER INGELHEIM, CHIESI, GSK, MENARINI GROUP, SANOFI. <b>MS<\/b> has nothing to declare. <b>A.P.<\/b> declares: research grants from CHIESI, ASTRAZENECA, GSK, SANOFI, Agenzia Payments Italiana del farmaco (AIFA); personal payments for consultation from Chiesi, ASTRAZENECA, GSK, NOVARTIS, SANOFI, AVILLION, ELPEN PHARMACEUTICA; Personal payments for lectures, presentations, or educational events from CHIESI, ASTRAZENECA, GSK, MENARINI, NOVARTIS, ZAMBON, MUNDIPHARMA, SANOFI, EDMOND PHARMA, IQVIA, AVILLION, ELPEN PHARMACEUTICALS; Personal payments for Advisory boards: CHIESI, ASTRAZENECA, GSK, MSD, NOVARTIS, SANOFI, IQVIA, AVILLION, ELPEN PHARMACEUTICALS; nothing to declare related to the present manuscript. <b>M.C<\/b> declares: research grants from Chiesi and GSK; personal payments for lectures, presentations or educational events from CHIESI, ASTRAZENECA, GSK, NOVARTIS, ZAMBON, SANOFI, ALK ABELLO; personal payments for participation on Advisory Board from CHIESI, ASTRAZENECA, GSK, ALK ABELLO, SANOFI; nothing to declare related to the present manuscript. All of the authors contributed to the study implementation, as well as to the development of this report.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest disclosure statement"}}],"article-number":"315"}}