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The participants provided their informed consent to participate in the study. All animal experiments were approved by the Ethical Committee and Institutional Review Board of the Jinling Hospital (#2021DZGKJDWLS-0089).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"180"}}