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All participants provided written informed consent prior to enrollment.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"S.H.C has served on advisory boards for CSL Behring, Pneumagen Ltd., Zaccha Pte Ltd, Boehringer-Ingelheim, GSK and Sanofi, on DSMBs for Inovio Pharmaceuticals and Imam Abdulrahman Bin Faisal University and has received personal fees from Astra-Zeneca, Boehringer-Ingelheim, CSL Behring and Chiesi Farmaceutici, all unrelated to this work. All other authors have no potential conflicts of interest to disclose.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"2"}}