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All experiments involving clinical samples were approved by the Institutional Review Board of the Tongji Medical College, Huazhong University of Science and Technology (approval ID: 2020-IEC-J-187). Informed consent was obtained from all patients, and all procedures were conducted in accordance with the principles of the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"108"}}