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Written informed consent was obtained from all participants. UK Biobank has obtained ethics approval from the North West Multi-centre Research Ethics Committee, and all participants provided written informed consent. The present analyses were conducted under UK Biobank Application No. 150455.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"379"}}