{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T06:39:33Z","timestamp":1782369573897,"version":"3.54.5"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"Asan Institute for Life Sciences, Asan Medical Center (KR)","award":["2016-714"],"award-info":[{"award-number":["2016-714"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Diabetol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s12933-016-0451-0","type":"journal-article","created":{"date-parts":[[2016,9,12]],"date-time":"2016-09-12T21:09:25Z","timestamp":1473714565000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Mortality and causes of death in a national sample of type 2 diabetic patients in Korea from 2002 to 2013"],"prefix":"10.1186","volume":"15","author":[{"given":"Yu Mi","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye-Jee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joong-Yeol","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo Je","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4043-2396","authenticated-orcid":false,"given":"Chang Hee","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,9,13]]},"reference":[{"issue":"1","key":"451_CR1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2337\/diacare.25.1.43","volume":"25","author":"NA Roper","year":"2002","unstructured":"Roper NA, Bilous RW, Kelly WF, Unwin NC, Connolly VM. Cause-specific mortality in a population with diabetes: south ttees diabetes mortality study. Diabetes Care. 2002;25(1):43\u20138.","journal-title":"Diabetes Care"},{"issue":"2","key":"451_CR2","doi-asserted-by":"crossref","first-page":"360","DOI":"10.2337\/diacare.26.2.360","volume":"26","author":"M Woodward","year":"2003","unstructured":"Woodward M, Zhang X, Barzi F, Pan W, Ueshima H, Rodgers A, MacMahon S. The effects of diabetes on the risks of major cardiovascular diseases and death in the Asia-Pacific region. Diabetes Care. 2003;26(2):360\u20136.","journal-title":"Diabetes Care"},{"issue":"8","key":"451_CR3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00405109","volume":"33","author":"J Head","year":"1990","unstructured":"Head J, Fuller JH. International variations in mortality among diabetic patients: the WHO multinational study of vascular disease in diabetics. Diabetologia. 1990;33(8):477\u201381.","journal-title":"Diabetologia"},{"issue":"1","key":"451_CR4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4093\/kdj.2009.33.1.65","volume":"33","author":"SK Park","year":"2009","unstructured":"Park SK, Park MK, Suk JH, Kim MK, Kim YK, Kim IJ, Kang YH, Lee KJ, Lee HS, Lee CW, et al. Cause-of-death trends for diabetes mellitus over 10\u00a0years. Korean Diabetes J. 2009;33(1):65\u201372.","journal-title":"Korean Diabetes J"},{"issue":"3","key":"451_CR5","doi-asserted-by":"crossref","first-page":"193","DOI":"10.4093\/dmj.2011.35.3.193","volume":"35","author":"S Suh","year":"2011","unstructured":"Suh S, Kim KW. Diabetes and cancer: is diabetes causally related to cancer? Diabetes Metabol J. 2011;35(3):193\u20138.","journal-title":"Diabetes Metabol J"},{"issue":"7","key":"451_CR6","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.2337\/diacare.21.7.1138","volume":"21","author":"K Gu","year":"1998","unstructured":"Gu K, Cowie CC, Harris MI. Mortality in adults with and without diabetes in a national cohort of the US population, 1971\u20131993. Diabetes Care. 1998;21(7):1138\u201345.","journal-title":"Diabetes Care"},{"issue":"7","key":"451_CR7","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.2337\/diacare.27.7.1605","volume":"27","author":"CH Tseng","year":"2004","unstructured":"Tseng CH. Mortality and causes of death in a national sample of diabetic patients in Taiwan. Diabetes Care. 2004;27(7):1605\u20139.","journal-title":"Diabetes Care"},{"issue":"2","key":"451_CR8","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3803\/EnM.2015.30.2.142","volume":"30","author":"KH Ha","year":"2015","unstructured":"Ha KH, Kim DJ. Trends in the diabetes epidemic in Korea. Endocrinol Metab. 2015;30(2):142\u20136.","journal-title":"Endocrinol Metab"},{"issue":"3","key":"451_CR9","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.diabres.2006.03.029","volume":"74","author":"YJ Choi","year":"2006","unstructured":"Choi YJ, Cho YM, Park CK, Jang HC, Park KS, Kim SY, Lee HK. Rapidly increasing diabetes-related mortality with socio-environmental changes in South Korea during the last two decades. Diabetes Res Clin Pract. 2006;74(3):295\u2013300.","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"451_CR10","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/(SICI)1096-9136(199704)14:4<316::AID-DIA328>3.0.CO;2-0","volume":"14","author":"W Gatling","year":"1997","unstructured":"Gatling W, Tufail S, Mullee MA, Westacott TA, Hill RD. Mortality rates in diabetic patients from a community-based population compared to local age\/sex matched controls. Diabet Med. 1997;14(4):316\u201320.","journal-title":"Diabet Med"},{"issue":"85","key":"451_CR11","first-page":"227","volume":"2009","author":"AH Zargar","year":"1003","unstructured":"Zargar AH, Wani AI, Masoodi SR, Bashir MI, Laway BA, Gupta VK, Wani FA. Causes of mortality in diabetes mellitus: data from a tertiary teaching hospital in India. Postgrad Med J. 1003;2009(85):227\u201332.","journal-title":"Postgrad Med J"},{"key":"451_CR12","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv319","author":"J Lee","year":"2016","unstructured":"Lee J, Lee JS, Park SH, Shin SA, Kim K. Cohort profile: The National Health Insurance Service-National Sample Cohort (NHIS-NSC), South Korea. Int J Epidemiol. 2016. doi: 10.1093\/ije\/dyv319 .","journal-title":"Int J Epidemiol"},{"issue":"10","key":"451_CR13","doi-asserted-by":"crossref","first-page":"e0139924","DOI":"10.1371\/journal.pone.0139924","volume":"10","author":"NH Kim","year":"2015","unstructured":"Kim NH, Lee J, Kim TJ, Kim NH, Choi KM, Baik SH, Choi DS, Pop-Busui R, Park Y, Kim SG. Body mass index and mortality in the general population and in subjects with chronic disease in Korea: a nationwide cohort study (2002\u20132010). PLoS ONE. 2015;10(10):e0139924.","journal-title":"PLoS ONE"},{"issue":"27","key":"451_CR14","doi-asserted-by":"crossref","first-page":"e4018","DOI":"10.1097\/MD.0000000000004018","volume":"95","author":"SH Ko","year":"2016","unstructured":"Ko SH, Kim DJ, Park JH, Park CY, Jung CH, Kwon HS, Park JY, Song KH, Han K, Lee KU, et al. Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002\u20132013: nationwide population-based cohort study. Medicine. 2016;95(27):e4018.","journal-title":"Medicine"},{"key":"451_CR15","unstructured":"Korean standard classification of diseases and causes of death (KCD-7). https:\/\/kssc.kostat.go.kr:8443\/ksscNew_web\/ekssc\/main\/main.do . Accessed 1 Apr 2016."},{"key":"451_CR16","unstructured":"KOSIS Statistical Database. http:\/\/kostat.go.kr\/portal\/korea\/kor_nw\/2\/6\/2\/index.board . Accessed 1 Apr 2016."},{"issue":"8","key":"451_CR17","doi-asserted-by":"crossref","first-page":"e12340","DOI":"10.1371\/journal.pone.0012340","volume":"5","author":"I Itskovich","year":"2010","unstructured":"Itskovich I, Roudebush B. Using re-sampling methods in mortality studies. PLoS One. 2010;5(8):e12340.","journal-title":"PLoS One"},{"issue":"9","key":"451_CR18","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.2337\/diacare.28.9.2280","volume":"28","author":"LC Lanting","year":"2005","unstructured":"Lanting LC, Joung IM, Mackenbach JP, Lamberts SW, Bootsma AH. Ethnic differences in mortality, end-stage complications, and quality of care among diabetic patients: a review. Diabetes Care. 2005;28(9):2280\u20138.","journal-title":"Diabetes Care"},{"issue":"18","key":"451_CR19","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1056\/NEJMoa1504347","volume":"373","author":"M Tancredi","year":"2015","unstructured":"Tancredi M, Rosengren A, Svensson AM, Kosiborod M, Pivodic A, Gudbjornsdottir S, Wedel H, Clements M, Dahlqvist S, Lind M. Excess mortality among persons with type 2 diabetes. N Engl J Med. 2015;373(18):1720\u201332.","journal-title":"N Engl J Med"},{"issue":"8","key":"451_CR20","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.2337\/diacare.23.8.1119","volume":"23","author":"E Brun","year":"2000","unstructured":"Brun E, Nelson RG, Bennett PH, Imperatore G, Zoppini G, Verlato G, Muggeo M. Diabetes duration and cause-specific mortality in the Verona Diabetes Study. Diabetes Care. 2000;23(8):1119\u201323.","journal-title":"Diabetes Care"},{"issue":"8","key":"451_CR21","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.2337\/diacare.23.8.1103","volume":"23","author":"CL Morgan","year":"2000","unstructured":"Morgan CL, Currie CJ, Peters JR. Relationship between diabetes and mortality: a population study using record linkage. Diabetes Care. 2000;23(8):1103\u20137.","journal-title":"Diabetes Care"},{"issue":"9","key":"451_CR22","doi-asserted-by":"crossref","first-page":"939","DOI":"10.2169\/internalmedicine.52.8276","volume":"52","author":"CC Chiu","year":"2013","unstructured":"Chiu CC, Huang CC, Chen YC, Chen TJ, Liang Y, Lin SJ, Chen JW, Leu HB, Chan WL. Increased risk of gastrointestinal malignancy in patients with diabetes mellitus and correlations with anti-diabetes drugs: a nationwide population-based study in Taiwan. Intern Med. 2013;52(9):939\u201346.","journal-title":"Intern Med"},{"issue":"7","key":"451_CR23","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.2337\/dc10-0666","volume":"33","author":"E Giovannucci","year":"2010","unstructured":"Giovannucci E, Harlan DM, Archer MC, Bergenstal RM, Gapstur SM, Habel LA, Pollak M, Regensteiner JG, Yee D. Diabetes and cancer: a consensus report. Diabetes Care. 2010;33(7):1674\u201385.","journal-title":"Diabetes Care"},{"issue":"4","key":"451_CR24","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3904\/kjim.2013.28.4.413","volume":"28","author":"H Kim","year":"2013","unstructured":"Kim H, Shin AR, Chung HH, Kim MK, Lee JS, Shim JJ, Kim BH. Recent trends in hepatitis B virus infection in the general Korean population. Korean J Intern Med. 2013;28(4):413\u20139.","journal-title":"Korean J Intern Med"},{"issue":"1\u20132","key":"451_CR25","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1159\/000087258","volume":"49","author":"HR Shin","year":"2006","unstructured":"Shin HR. Epidemiology of hepatitis C virus in Korea. Intervirology. 2006;49(1\u20132):18\u201322.","journal-title":"Intervirology"},{"issue":"5 Suppl 1","key":"451_CR26","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1053\/j.gastro.2004.09.014","volume":"127","author":"G Fattovich","year":"2004","unstructured":"Fattovich G, Stroffolini T, Zagni I, Donato F. Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology. 2004;127(5 Suppl 1):S35\u201350.","journal-title":"Gastroenterology"},{"key":"451_CR27","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s12933-015-0226-z","volume":"14","author":"MP Hermans","year":"2015","unstructured":"Hermans MP, Bouenizabila E, Amoussou-Guenou DK, Ahn SA, Rousseau MF. Baseline diabetes as a way to predict CV outcomes in a lipid-modifying trial: a meta-analysis of 330,376 patients from 47 landmark studies. Cardiovasc Diabetol. 2015;14:60.","journal-title":"Cardiovasc Diabetol"},{"issue":"7","key":"451_CR28","doi-asserted-by":"crossref","first-page":"e1002026","DOI":"10.1371\/journal.pmed.1002026","volume":"13","author":"F Bragg","year":"2016","unstructured":"Bragg F, Li L, Yang L, Guo Y, Chen Y, Bian Z, Chen J, Collins R, Peto R, Wang C, et al. Risks and population burden of cardiovascular diseases associated with diabetes in China: a prospective study of 0.5 million adults. PLoS Med. 2016;13(7):e1002026.","journal-title":"PLoS Med"},{"issue":"1","key":"451_CR29","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5853\/jos.2013.15.1.2","volume":"15","author":"KS Hong","year":"2013","unstructured":"Hong KS, Bang OY, Kang DW, Yu KH, Bae HJ, Lee JS, Heo JH, Kwon SU, Oh CW, Lee BC, et al. Stroke statistics in Korea: part I. Epidemiology and risk factors: a report from the Korean stroke society and clinical research center for stroke. J Stroke. 2013;15(1):2\u201320.","journal-title":"J Stroke"},{"issue":"Suppl 2","key":"451_CR30","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1007\/PL00002934","volume":"44","author":"NJ Morrish","year":"2001","unstructured":"Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes. Diabetologia. 2001;44(Suppl 2):S14\u201321.","journal-title":"Diabetologia"},{"key":"451_CR31","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12933-015-0204-5","volume":"14","author":"L Cea Soriano","year":"2015","unstructured":"Cea Soriano L, Johansson S, Stefansson B, Rodriguez LA. Cardiovascular events and all-cause mortality in a cohort of 57,946 patients with type 2 diabetes: associations with renal function and cardiovascular risk factors. Cardiovasc Diabetol. 2015;14:38.","journal-title":"Cardiovasc Diabetol"},{"key":"451_CR32","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.2337\/dc16-0429","volume":"39","author":"Q Gong","year":"2016","unstructured":"Gong Q, Zhang P, Wang J, An Y, Gregg EW, Li H, Zhang B, Shuai Y, Yang W, Chen Y, et al. Changes in mortality in people with IGT before and after the onset of diabetes during the 23-year follow-up of the Da Qing diabetes prevention study. Diabetes Care. 2016;39:1550\u20135.","journal-title":"Diabetes Care"},{"key":"451_CR33","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1475-2840-13-3","volume":"13","author":"A Lopez-de-Andres","year":"2014","unstructured":"Lopez-de-Andres A, Jimenez-Garcia R, Hernandez-Barrera V, Perez-Farinos N, de Miguel-Yanes JM, Mendez-Bailon M, Jimenez-Trujillo I, de Miguel AG, Pino CG, Carrasco-Garrido P. National trends in utilization and outcomes of coronary revascularization procedures among people with and without type 2 diabetes in Spain (2001\u20132011). Cardiovasc Diabetol. 2014;13:3.","journal-title":"Cardiovasc Diabetol"},{"key":"451_CR34","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12933-014-0135-6","volume":"13","author":"MA Miselli","year":"2014","unstructured":"Miselli MA, Nora ED, Passaro A, Tomasi F, Zuliani G. Plasma triglycerides predict ten-years all-cause mortality in outpatients with type 2 diabetes mellitus: a longitudinal observational study. Cardiovasc Diabetol. 2014;13:135.","journal-title":"Cardiovasc Diabetol"},{"key":"451_CR35","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s12933-015-0305-1","volume":"14","author":"KB Won","year":"2015","unstructured":"Won KB, Hur SH, Cho YK, Yoon HJ, Nam CW, Kim KB, Bae JH, Choi DJ, Ahn YK, Park JS, et al. Comparison of 2-year mortality according to obesity in stabilized patients with type 2 diabetes mellitus after acute myocardial infarction: results from the DIAMOND prospective cohort registry. Cardiovasc Diabetol. 2015;14:141.","journal-title":"Cardiovasc Diabetol"},{"key":"451_CR36","doi-asserted-by":"crossref","first-page":"30329","DOI":"10.1038\/srep30329","volume":"6","author":"HK Yang","year":"2016","unstructured":"Yang HK, Han K, Kwon HS, Park YM, Cho JH, Yoon KH, Kang MI, Cha BY, Lee SH. Obesity, metabolic health, and mortality in adults: a nationwide population-based study in Korea. Sci Rep. 2016;6:30329.","journal-title":"Sci Rep"},{"key":"451_CR37","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s12933-015-0267-3","volume":"14","author":"F Jiao","year":"2015","unstructured":"Jiao F, Fung CS, Wan YF, McGhee SM, Wong CK, Dai D, Kwok R, Lam CL. Long-term effects of the multidisciplinary risk assessment and management program for patients with diabetes mellitus (RAMP-DM): a population-based cohort study. Cardiovasc Diabetol. 2015;14:105.","journal-title":"Cardiovasc Diabetol"},{"key":"451_CR38","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12933-015-0179-2","volume":"14","author":"T Wilke","year":"2015","unstructured":"Wilke T, Mueller S, Groth A, Fuchs A, Seitz L, Kienhofer J, Maywald U, Lundershausen R, Wehling M. Treatment-dependent and treatment-independent risk factors associated with the risk of diabetes-related events: a retrospective analysis based on 229,042 patients with type 2 diabetes mellitus. Cardiovasc Diabetol. 2015;14:14.","journal-title":"Cardiovasc Diabetol"},{"key":"451_CR39","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12933-015-0300-6","volume":"14","author":"PK Bundhun","year":"2015","unstructured":"Bundhun PK, Li N, Chen MH. Adverse cardiovascular outcomes between insulin-treated and non-insulin treated diabetic patients after percutaneous coronary intervention: a systematic review and meta-analysis. Cardiovasc Diabetol. 2015;14:135.","journal-title":"Cardiovasc Diabetol"},{"issue":"50","key":"451_CR40","doi-asserted-by":"crossref","first-page":"e2313","DOI":"10.1097\/MD.0000000000002313","volume":"94","author":"PK Bundhun","year":"2015","unstructured":"Bundhun PK, Wu ZJ, Chen MH. Impact of modifiable cardiovascular risk factors on mortality after percutaneous coronary intervention: a systematic review and meta-analysis of 100 studies. Medicine. 2015;94(50):e2313.","journal-title":"Medicine"},{"issue":"Suppl 2","key":"451_CR41","doi-asserted-by":"crossref","first-page":"S253","DOI":"10.2337\/dc09-S318","volume":"32","author":"SG Swinnen","year":"2009","unstructured":"Swinnen SG, Hoekstra JB, DeVries JH. Insulin therapy for type 2 diabetes. Diabetes Care. 2009;32(Suppl 2):S253\u20139.","journal-title":"Diabetes Care"},{"issue":"4","key":"451_CR42","doi-asserted-by":"crossref","first-page":"303","DOI":"10.4093\/dmj.2011.35.4.303","volume":"35","author":"DJ Kim","year":"2011","unstructured":"Kim DJ. The epidemiology of diabetes in Korea. Diabetes Metab J. 2011;35(4):303\u20138.","journal-title":"Diabetes Metab J"},{"issue":"1","key":"451_CR43","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4093\/dmj.2016.40.1.35","volume":"40","author":"SO Song","year":"2016","unstructured":"Song SO, Song YD, Nam JY, Park KH, Yoon JH, Son KM, Ko Y, Lim DH. Epidemiology of type 1 diabetes mellitus in Korea through an investigation of the National registration project of type 1 diabetes for the reimbursement of glucometer strips with additional analyses using claims data. Diabetes Metab J. 2016;40(1):35\u201345.","journal-title":"Diabetes Metab J"},{"key":"451_CR44","volume-title":"National diabetes statistics report: estimates of diabetes and its burden in the United States, 2014","author":"Centers for Disease Control and Prevention","year":"2014","unstructured":"Centers for Disease Control and Prevention. National diabetes statistics report: estimates of diabetes and its burden in the United States, 2014. Atlanta: Department of Health and Human Services; 2014."},{"issue":"5","key":"451_CR45","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/BF00251820","volume":"24","author":"JH Fuller","year":"1983","unstructured":"Fuller JH, Elford J, Goldblatt P, Adelstein AM. Diabetes mortality: new light on an underestimated public health problem. Diabetologia. 1983;24(5):336\u201341.","journal-title":"Diabetologia"},{"key":"451_CR46","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2016.105","author":"P Zimmet","year":"2016","unstructured":"Zimmet P, Alberti KG, Magliano DJ, Bennett PH. Diabetes mellitus statistics on prevalence and mortality: facts and fallacies. Nat Rev Endocrinol. 2016. doi: 10.1038\/nrendo.2016.105 .","journal-title":"Nat Rev Endocrinol."}],"container-title":["Cardiovascular Diabetology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12933-016-0451-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T08:02:37Z","timestamp":1568361757000},"score":1,"resource":{"primary":{"URL":"http:\/\/cardiab.biomedcentral.com\/articles\/10.1186\/s12933-016-0451-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,13]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["451"],"URL":"https:\/\/doi.org\/10.1186\/s12933-016-0451-0","relation":{},"ISSN":["1475-2840"],"issn-type":[{"value":"1475-2840","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,13]]},"article-number":"131"}}