{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T13:45:22Z","timestamp":1793108722449,"version":"4.5.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Diabetol"],"DOI":"10.1186\/s12933-024-02411-y","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T14:02:43Z","timestamp":1725372163000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Fully automated epicardial adipose tissue volume quantification with deep learning and relationship with CAC score and micro\/macrovascular complications in people living with type 2 diabetes: the multicenter EPIDIAB study"],"prefix":"10.1186","volume":"23","author":[{"given":"B\u00e9n\u00e9dicte","family":"Gaborit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Baptiste","family":"Julla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joris","family":"Fournel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Ancel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Soghomonian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Deprade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e8le","family":"Lasbleiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Houssays","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Badih","family":"Ghattas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Gascon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maud","family":"Righini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Matonti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Venteclef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Potier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Fran\u00e7ois","family":"Gautier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9mie","family":"Resseguier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Bartoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Mourre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Darmon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Jacquier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Dutour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"issue":"5","key":"2411_CR1","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1161\/CIRCULATIONAHA.107.743062","volume":"117","author":"GA Rosito","year":"2008","unstructured":"Rosito GA, Massaro JM, Hoffmann U, Ruberg FL, Mahabadi AA, Vasan RS, et al. Pericardial Fat, Visceral Abdominal Fat, Cardiovascular Disease Risk Factors, and Vascular Calcification in a Community-Based Sample: The Framingham Heart Study. Circulation. 2008;117(5):605\u201313.","journal-title":"Circulation"},{"issue":"1","key":"2411_CR2","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1152\/physrev.00033.2011","volume":"93","author":"A Tchernof","year":"2013","unstructured":"Tchernof A, Despres JP. Pathophysiology of Human Visceral Obesity: An Update. Physiol Rev. 2013;93(1):359\u2013404.","journal-title":"Physiol Rev"},{"issue":"6","key":"2411_CR3","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1007\/s00125-016-3933-4","volume":"59","author":"V Pellegrinelli","year":"2016","unstructured":"Pellegrinelli V, Carobbio S, Vidal-Puig A. Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues. Diabetologia. 2016;59(6):1075\u201388.","journal-title":"Diabetologia"},{"issue":"9","key":"2411_CR4","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1038\/s41569-022-00679-9","volume":"19","author":"G Iacobellis","year":"2022","unstructured":"Iacobellis G. Epicardial adipose tissue in contemporary cardiology. Nat Rev Cardiol. 2022;19(9):593\u2013606.","journal-title":"Nat Rev Cardiol"},{"issue":"3","key":"2411_CR5","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1002\/cphy.c160034","volume":"7","author":"B Gaborit","year":"2017","unstructured":"Gaborit B, Sengenes C, Ancel P, Jacquier A, Dutour A. Role of Epicardial Adipose Tissue in Health and Disease: A Matter of Fat? Compr Physiol. 2017;7(3):1051\u201382.","journal-title":"Compr Physiol"},{"issue":"7","key":"2411_CR6","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1161\/ATVBAHA.110.204719","volume":"30","author":"K Karastergiou","year":"2010","unstructured":"Karastergiou K, Evans I, Ogston N, Miheisi N, Nair D, Kaski JC, et al. Epicardial adipokines in obesity and coronary artery disease induce atherogenic changes in monocytes and endothelial cells. Arterioscler Thromb Vasc Biol. 2010;30(7):1340\u20136.","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"3","key":"2411_CR7","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.jacc.2011.01.048","volume":"58","author":"Y Hirata","year":"2011","unstructured":"Hirata Y, Tabata M, Kurobe H, Motoki T, Akaike M, Nishio C, et al. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue. J Am Coll Cardiol. 2011;58(3):248\u201355.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"2411_CR8","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1093\/cvr\/cvv208","volume":"108","author":"B Gaborit","year":"2015","unstructured":"Gaborit B, Venteclef N, Ancel P, Pelloux V, Gariboldi V, Leprince P, et al. Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location. Cardiovasc Res. 2015;108(1):62\u201373.","journal-title":"Cardiovasc Res"},{"issue":"43","key":"2411_CR9","doi-asserted-by":"publisher","first-page":"3529","DOI":"10.1093\/eurheartj\/ehz592","volume":"40","author":"EK Oikonomou","year":"2019","unstructured":"Oikonomou EK, Williams MC, Kotanidis CP, Desai MY, Marwan M, Antonopoulos AS, et al. A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography. Eur Heart J. 2019;40(43):3529\u201343.","journal-title":"Eur Heart J"},{"key":"2411_CR10","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15634","author":"CP Kotanidis","year":"2021","unstructured":"Kotanidis CP, Antoniades C. Perivascular Fat Imaging by Computed Tomography: A Virtual Guide. Br J Pharmacol. 2021. https:\/\/doi.org\/10.1111\/bph.15634.","journal-title":"Br J Pharmacol."},{"issue":"10151","key":"2411_CR11","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1016\/S0140-6736(18)31114-0","volume":"392","author":"EK Oikonomou","year":"2018","unstructured":"Oikonomou EK, Marwan M, Desai MY, Mancio J, Alashi A, Hutt Centeno E, et al. Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data. Lancet. 2018;392(10151):929\u201339.","journal-title":"Lancet"},{"issue":"13","key":"2411_CR12","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/j.jacc.2012.11.062","volume":"61","author":"AA Mahabadi","year":"2013","unstructured":"Mahabadi AA, Berg MH, Lehmann N, K\u00e4lsch H, Bauer M, Kara K, et al. Association of epicardial fat with cardiovascular risk factors and incident myocardial infarction in the general population: the Heinz Nixdorf Recall Study. J Am Coll Cardiol. 2013;61(13):1388\u201395.","journal-title":"J Am Coll Cardiol"},{"issue":"24","key":"2411_CR13","first-page":"00596","volume":"S0140\u20136736","author":"K Chan","year":"2024","unstructured":"Chan K, Wahome E, Tsiachristas A, Antonopoulos AS, Patel P, Lyasheva M, et al. Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study. Lancet. 2024;S0140\u20136736(24):00596\u20138.","journal-title":"Lancet"},{"issue":"6","key":"2411_CR14","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1038\/oby.2011.283","volume":"20","author":"B Gaborit","year":"2012","unstructured":"Gaborit B, Kober F, Jacquier A, Moro PJ, Flavian A, Quilici J, et al. Epicardial fat volume is associated with coronary microvascular response in healthy subjects: a pilot study. Obesity (Silver Spring). 2012;20(6):1200\u20135.","journal-title":"Obesity (Silver Spring)"},{"issue":"9","key":"2411_CR15","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1016\/j.jcmg.2014.07.002","volume":"7","author":"AA Mahabadi","year":"2014","unstructured":"Mahabadi AA, Lehmann N, K\u00e4lsch H, Robens T, Bauer M, Dykun I, et al. Association of epicardial adipose tissue with progression of coronary artery calcification is more pronounced in the early phase of atherosclerosis: results from the Heinz Nixdorf recall study. JACC Cardiovasc Imaging. 2014;7(9):909\u201316.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"1","key":"2411_CR16","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s12933-019-0807-3","volume":"18","author":"Y Li","year":"2019","unstructured":"Li Y, Liu B, Li Y, Jing X, Deng S, Yan Y, et al. Epicardial fat tissue in patients with diabetes mellitus: a systematic review and meta-analysis. Cardiovasc Diabetol. 2019;18(1):3.","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"2411_CR17","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1186\/s12967-016-0999-1","volume":"14","author":"I Moreno-Santos","year":"2016","unstructured":"Moreno-Santos I, P\u00e9rez-Belmonte LM, Mac\u00edas-Gonz\u00e1lez M, Matar\u00f3 MJ, Castellano D, L\u00f3pez-Garrido M, et al. Type 2 diabetes is associated with decreased PGC1\u03b1 expression in epicardial adipose tissue of patients with coronary artery disease. J Transl Med. 2016;14(1):243.","journal-title":"J Transl Med"},{"issue":"13","key":"2411_CR18","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.87460","volume":"1","author":"S Ojha","year":"2016","unstructured":"Ojha S, Fainberg HP, Wilson V, Pelella G, Castellanos M, May ST, et al. Gene pathway development in human epicardial adipose tissue during early life. JCI Insight. 2016;1(13).","journal-title":"JCI Insight"},{"issue":"38","key":"2411_CR19","doi-asserted-by":"publisher","first-page":"3827","DOI":"10.1093\/eurheartj\/ehad484","volume":"44","author":"C Antoniades","year":"2023","unstructured":"Antoniades C, Tousoulis D, Vavlukis M, Fleming I, Duncker DJ, Eringa E, et al. Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers. Eur Heart J. 2023;44(38):3827\u201344.","journal-title":"Eur Heart J"},{"issue":"3","key":"2411_CR20","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1038\/ijo.2011.117","volume":"36","author":"B Gaborit","year":"2012","unstructured":"Gaborit B, Kober F, Jacquier A, Moro PJ, Cuisset T, Boullu S, et al. Assessment of epicardial fat volume and myocardial triglyceride content in severely obese subjects: relationship to metabolic profile, cardiac function and visceral fat. Int J Obes (Lond). 2012;36(3):422\u201330.","journal-title":"Int J Obes (Lond)"},{"issue":"6","key":"2411_CR21","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.3390\/cells11061034","volume":"11","author":"A Bartoli","year":"2022","unstructured":"Bartoli A, Fournel J, Ait-Yahia L, Cadour F, Tradi F, Ghattas B, et al. Automatic Deep-Learning Segmentation of Epicardial Adipose Tissue from Low-Dose Chest CT and Prognosis Impact on COVID-19. Cells. 2022;11(6):1034.","journal-title":"Cells"},{"key":"2411_CR22","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgz069","author":"B Gaborit","year":"2020","unstructured":"Gaborit B, Julla JB, Besbes S, Proust M, Vincentelli C, Alos B, et al. Glucagon-like Peptide 1 Receptor Agonists, Diabetic Retinopathy and Angiogenesis: The AngioSafe Type 2 Diabetes Study. J Clin Endocrinol Metab. 2020. https:\/\/doi.org\/10.1210\/clinem\/dgz069.","journal-title":"J Clin Endocrinol Metab."},{"issue":"9","key":"2411_CR23","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1016\/S0161-6420(03)00475-5","volume":"110","author":"CP Wilkinson","year":"2003","unstructured":"Wilkinson CP, Ferris FL, Klein RE, Lee PP, Agardh CD, Davis M, et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110(9):1677\u201382.","journal-title":"Ophthalmology"},{"issue":"9","key":"2411_CR24","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1016\/j.mri.2012.05.001","volume":"30","author":"A Fedorov","year":"2012","unstructured":"Fedorov A, Beichel R, Kalpathy-Cramer J, Finet J, Fillion-Robin JC, Pujol S, et al. 3D Slicer as an image computing platform for the Quantitative Imaging Network. Magn Reson Imaging. 2012;30(9):1323\u201341.","journal-title":"Magn Reson Imaging"},{"issue":"4","key":"2411_CR25","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1007\/s13139-012-0175-3","volume":"46","author":"WH Kim","year":"2012","unstructured":"Kim WH, Kim CG, Kim DW. Optimal CT Number Range for Adipose Tissue When Determining Lean Body Mass in Whole-Body F-18 FDG PET\/CT Studies. Nucl Med Mol Imaging. 2012;46(4):294\u20139.","journal-title":"Nucl Med Mol Imaging"},{"issue":"1","key":"2411_CR26","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.ijcard.2011.04.021","volume":"161","author":"T Oka","year":"2012","unstructured":"Oka T, Yamamoto H, Ohashi N, Kitagawa T, Kunita E, Utsunomiya H, et al. Association between epicardial adipose tissue volume and characteristics of non-calcified plaques assessed by coronary computed tomographic angiography. Int J Cardiol. 2012;161(1):45\u20139.","journal-title":"Int J Cardiol"},{"issue":"6","key":"2411_CR27","doi-asserted-by":"publisher","DOI":"10.1148\/ryai.2019190045","volume":"1","author":"F Commandeur","year":"2019","unstructured":"Commandeur F, Goeller M, Razipour A, Cadet S, Hell MM, Kwiecinski J, et al. Fully Automated CT Quantification of Epicardial Adipose Tissue by Deep Learning: A Multicenter Study. Radiol Artif Intell. 2019;1(6).","journal-title":"Radiol Artif Intell"},{"issue":"8","key":"2411_CR28","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1109\/TMI.2018.2804799","volume":"37","author":"F Commandeur","year":"2018","unstructured":"Commandeur F, Goeller M, Betancur J, Cadet S, Doris M, Chen X, et al. Deep Learning for Quantification of Epicardial and Thoracic Adipose Tissue From Non-Contrast CT. IEEE Trans Med Imaging. 2018;37(8):1835\u201346.","journal-title":"IEEE Trans Med Imaging"},{"key":"2411_CR29","doi-asserted-by":"publisher","DOI":"10.1002\/oby.24023","author":"E Doukbi","year":"2024","unstructured":"Doukbi E, Ancel P, Dutour A, Soghomonian A, Ahmed S, Castejon V, et al. Human epicardial fat has a beige profile and contains higher type 2 innate lymphoid cells than subcutaneous fat. Obesity (Silver Spring). 2024. https:\/\/doi.org\/10.1002\/oby.24023.","journal-title":"Obesity (Silver Spring)."},{"issue":"4","key":"2411_CR30","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.diabet.2018.08.005","volume":"45","author":"F Liu","year":"2019","unstructured":"Liu F, Wang H, Feng W, Ye X, Sun X, Jiang C, et al. Type 1 innate lymphoid cells are associated with type 2 diabetes. Diabetes Metab. 2019;45(4):341\u20136.","journal-title":"Diabetes Metab"},{"key":"2411_CR31","doi-asserted-by":"publisher","DOI":"10.2337\/db23-0926","author":"C Diamond","year":"2024","unstructured":"Diamond C, Pansini M, Hamid A, Eichert N, Pandya P, Ali SN, et al. Quantitative imaging reveals steatosis and fibro-inflammation in multiple organs in people with type 2 diabetes: a real-world study. Diabetes. 2024. https:\/\/doi.org\/10.2337\/db23-0926.","journal-title":"Diabetes."},{"issue":"12","key":"2411_CR32","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1038\/s41577-019-0213-9","volume":"19","author":"MY Donath","year":"2019","unstructured":"Donath MY, Dinarello CA, Mandrup-Poulsen T. Targeting innate immune mediators in type 1 and type 2 diabetes. Nat Rev Immunol. 2019;19(12):734\u201346.","journal-title":"Nat Rev Immunol"},{"issue":"12","key":"2411_CR33","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","volume":"377","author":"PM Ridker","year":"2017","unstructured":"Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J Med. 2017;377(12):1119\u201331.","journal-title":"N Engl J Med"},{"issue":"12","key":"2411_CR34","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.013104","volume":"8","author":"P Raggi","year":"2019","unstructured":"Raggi P, Gadiyaram V, Zhang C, Chen Z, Lopaschuk G, Stillman AE. Statins Reduce Epicardial Adipose Tissue Attenuation Independent of Lipid Lowering: A Potential Pleiotropic Effect. J Am Heart Assoc. 2019;8(12).","journal-title":"J Am Heart Assoc"},{"issue":"12","key":"2411_CR35","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1161\/CIRCULATIONAHA.108.821181","volume":"119","author":"AS Greenstein","year":"2009","unstructured":"Greenstein AS, Khavandi K, Withers SB, Sonoyama K, Clancy O, Jeziorska M, et al. Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients. Circulation. 2009;119(12):1661\u201370.","journal-title":"Circulation"},{"key":"2411_CR36","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.freeradbiomed.2019.11.002","volume":"146","author":"L Azul","year":"2020","unstructured":"Azul L, Leandro A, Boroumand P, Klip A, Sei\u00e7a R, Sena CM. Increased inflammation, oxidative stress and a reduction in antioxidant defense enzymes in perivascular adipose tissue contribute to vascular dysfunction in type 2 diabetes. Free Radic Biol Med. 2020;146:264\u201374.","journal-title":"Free Radic Biol Med"},{"issue":"1","key":"2411_CR37","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s12933-021-01225-6","volume":"20","author":"E Cosson","year":"2021","unstructured":"Cosson E, Nguyen MT, Rezgani I, Tatulashvili S, Sal M, Berkane N, et al. Epicardial adipose tissue volume and coronary calcification among people living with diabetes: a cross-sectional study. Cardiovasc Diabetol. 2021;20(1):35.","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"2411_CR38","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1186\/s12933-021-01420-5","volume":"20","author":"E Cosson","year":"2021","unstructured":"Cosson E, Nguyen MT, Rezgani I, Berkane N, Pinto S, Bihan H, et al. Epicardial adipose tissue volume and myocardial ischemia in asymptomatic people living with diabetes: a cross-sectional study. Cardiovasc Diabetol. 2021;20(1):224.","journal-title":"Cardiovasc Diabetol"},{"key":"2411_CR39","doi-asserted-by":"publisher","DOI":"10.2174\/0115734056291770240105101731","author":"Z Wang","year":"2024","unstructured":"Wang Z, Huang Z, Wang X. The Correlation between Region-specific Epicardial Adipose Tissue and Myocardial Ischemia Defined by CT-FFR in Type 2 Diabetes Mellitus Patients. Curr Med Imaging. 2024. https:\/\/doi.org\/10.2174\/0115734056291770240105101731.","journal-title":"Curr Med Imaging."},{"issue":"1","key":"2411_CR40","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s12933-019-0931-0","volume":"18","author":"C Sardu","year":"2019","unstructured":"Sardu C, D\u2019Onofrio N, Torella M, Portoghese M, Loreni F, Mureddu S, et al. Pericoronary fat inflammation and Major Adverse Cardiac Events (MACE) in prediabetic patients with acute myocardial infarction: effects of metformin. Cardiovasc Diabetol. 2019;18(1):126.","journal-title":"Cardiovasc Diabetol"},{"issue":"2","key":"2411_CR41","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1210\/jc.2008-0834","volume":"94","author":"TD Wang","year":"2009","unstructured":"Wang TD, Lee WJ, Shih FY, Huang CH, Chang YC, Chen WJ, et al. Relations of epicardial adipose tissue measured by multidetector computed tomography to components of the metabolic syndrome are region-specific and independent of anthropometric indexes and intraabdominal visceral fat. J Clin Endocrinol Metab. 2009;94(2):662\u20139.","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"2411_CR42","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1177\/2047487317689976","volume":"24","author":"B Gaborit","year":"2017","unstructured":"Gaborit B, Dutour A. Looking beyond ectopic fat amount: A SMART method to quantify epicardial adipose tissue density. Eur J Prev Cardiol. 2017;24(6):657\u20139.","journal-title":"Eur J Prev Cardiol"},{"issue":"1","key":"2411_CR43","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/s12933-019-0917-y","volume":"18","author":"RH Christensen","year":"2019","unstructured":"Christensen RH, von Scholten BJ, Hansen CS, Jensen MT, Vilsb\u00f8ll T, Rossing P, et al. Epicardial adipose tissue predicts incident cardiovascular disease and mortality in patients with type 2 diabetes. Cardiovasc Diabetol. 2019;18(1):114.","journal-title":"Cardiovasc Diabetol"}],"container-title":["Cardiovascular Diabetology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12933-024-02411-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12933-024-02411-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12933-024-02411-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T14:06:09Z","timestamp":1725372369000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiab.biomedcentral.com\/articles\/10.1186\/s12933-024-02411-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2411"],"URL":"https:\/\/doi.org\/10.1186\/s12933-024-02411-y","relation":{},"ISSN":["1475-2840"],"issn-type":[{"value":"1475-2840","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,3]]},"assertion":[{"value":"1 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"BG is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data access and responsibility"}}],"article-number":"328"}}