{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T07:24:24Z","timestamp":1787124264048,"version":"build-2736575974"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Max Planck Institute for Dynamics of Complex Technical Systems (MPI Magdeburg)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Microb Cell Fact"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Zymomonas mobilis<\/jats:italic>\n                    has a typical F\n                    <jats:sub>O<\/jats:sub>\n                    F\n                    <jats:sub>1<\/jats:sub>\n                    ATPase, yet does not exhibit oxidative phosphorylation. In order to investigate the function of the ATPase we sought to delete the F\n                    <jats:sub>O<\/jats:sub>\n                    and the F\n                    <jats:sub>1<\/jats:sub>\n                    subcomplexes, respectively. Clean mutants could be obtained after selection under aerobic conditions. Growth analysis of the mutants showed that they strictly require oxygen for growth and that the oxygen supply is a factor determining maximal growth rate. This is contrary to the wild type, which grows fastest under anaerobic conditions. In the mutant strains, ethanol remains the main catabolic product; however glucose consumption rates are reduced, and the mutants show a higher sensitivity to low medium pH. Compared to the wild type, the mutants show an increased biomass yield. Our data support the previously proposed regulatory role of the F\n                    <jats:sub>O<\/jats:sub>\n                    F\n                    <jats:sub>1<\/jats:sub>\n                    ATPase in controlling glycolytic flux, and indicate that the F\n                    <jats:sub>O<\/jats:sub>\n                    F\n                    <jats:sub>1<\/jats:sub>\n                    ATPase plays an important role in expelling protons from the cytoplasm. In the mutants, this function is taken over by the electron transport chain in the presence of oxygen.\n                  <\/jats:p>","DOI":"10.1186\/s12934-026-03059-x","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T12:46:19Z","timestamp":1783946779000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigating the role of FOF1 ATPase in Zymomonas mobilis through deletion of its FO and F1 subcomplexes"],"prefix":"10.1186","volume":"25","author":[{"given":"Gerrich","family":"Behrendt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinis","family":"Rutkis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uldis","family":"Kalnenieks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Bettenbrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"3059_CR1","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1111\/1751-7915.13439","volume":"12","author":"A Arce-Rodr\u00edguez","year":"2019","unstructured":"Arce-Rodr\u00edguez A, Volke DC, Bense S, H\u00e4ussler S, Nikel P. Non-invasive ratiometric determination of intracellular pH in Pseudomonas species using a novel genetically encoded indicator. Microb Biotechnol. 2019;12:799\u2013813. https:\/\/doi.org\/10.1111\/1751-7915.13439.","journal-title":"Microb Biotechnol"},{"issue":"11","key":"3059_CR2","doi-asserted-by":"publisher","first-page":"3855","DOI":"10.1021\/acssynbio.2c00428","volume":"11","author":"G Behrendt","year":"2022","unstructured":"Behrendt G, Frohwitter J, Vlachonikolou M, Klamt S, Bettenbrock K. Zymo-Parts: A Golden Gate Modular Cloning Toolbox for Heterologous Gene Expression in Zymomonas mobilis. ACS Synth Biol. 2022;11(11):3855\u201364. https:\/\/doi.org\/10.1021\/acssynbio.2c00428.","journal-title":"ACS Synth Biol"},{"key":"3059_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/1751-7915.14381","volume":"August 2023","author":"G Behrendt","year":"2024","unstructured":"Behrendt G, Vlachonikolou M, Tietgens H, Bettenbrock K. Construction and comparison of different vehicles for heterologous gene expression in Zymomonas mobilis. Microb Biotechnol. 2024;August 2023:1\u201320. https:\/\/doi.org\/10.1111\/1751-7915.14381.","journal-title":"Microb Biotechnol"},{"issue":"5","key":"3059_CR4","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1128\/jb.89.5.1195-1200.1965","volume":"89","author":"JP Bela\u00efch","year":"1965","unstructured":"Bela\u00efch JP, Senez JC. Influence of Aeration and of Pantothenate on Growth Yields of Zymomonas. J Bacteriol. 1965;89(5):1195\u2013200.","journal-title":"J Bacteriol"},{"key":"3059_CR5","doi-asserted-by":"publisher","unstructured":"Boecker S, Zahoor A, Schramm T, Link H, Klamt S. Broadening the Scope of Enforced ATP Wasting as a Tool for Metabolic Engineering in Escherichia coli. Biotechnol J. 2019;14(9). https:\/\/doi.org\/10.1002\/biot.201800438.","DOI":"10.1002\/biot.201800438"},{"issue":"5","key":"3059_CR6","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1111\/mmi.14380","volume":"112","author":"L Brenac","year":"2019","unstructured":"Brenac L, Baidoo EEK, Keasling JD, Budin I. Distinct functional roles for hopanoid composition in the chemical tolerance of \\textit{Zymomonas mobilis}. Mol Microbiol. 2019;112(5):1564\u201375. https:\/\/doi.org\/10.1111\/mmi.14380.","journal-title":"Mol Microbiol"},{"issue":"4","key":"3059_CR7","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1007\/BF00408383","volume":"139","author":"S Bringer","year":"1984","unstructured":"Bringer S, Finn RK, Sahm H. Effect of oxygen on the metabolism of Zymomonas mobilis. Arch Microbiol. 1984;139(4):376\u201381. https:\/\/doi.org\/10.1007\/BF00408383.","journal-title":"Arch Microbiol"},{"key":"3059_CR8","doi-asserted-by":"publisher","unstructured":"Cao LY, Yang YF, Zhang X, Chen YH, Yao JW, Wang X, Xia J, Liu CG, Yang SH, R\u00f6mling U, Bai FW. Deciphering Molecular Mechanism Underlying Self-Flocculation of Zymomonas mobilis for Robust Production. Appl Environ Microbiol. 2022;88(9). https:\/\/doi.org\/10.1128\/aem.02398-21.","DOI":"10.1128\/aem.02398-21"},{"key":"3059_CR9","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/0022-2836(87)90667-X","volume":"194","author":"AL Cozens","year":"1987","unstructured":"Cozens AL, Walker JE. The Organization and Sequence of the Genes for ATP Synthase Subunits in the Cyanobacterium Synechococcus 6301 Support for an Endosymbiotic Origin of Chloroplasts. J Mol Biol. 1987;194:359.","journal-title":"J Mol Biol"},{"key":"3059_CR10","doi-asserted-by":"publisher","unstructured":"Engler C, Gruetzner R, Kandzia R, Marillonnet S. Golden gate shuffling: A one-pot DNA shuffling method based on type ils restriction enzymes. PLoS ONE. 2009;4(5). https:\/\/doi.org\/10.1371\/journal.pone.0005553.","DOI":"10.1371\/journal.pone.0005553"},{"key":"3059_CR11","doi-asserted-by":"publisher","unstructured":"Enright AL, Banta AB, Ward RD, Vazquez JR, Felczak MM, Wolfe MB, TerAvest MA, Amador-Noguez D, Peters JM. The genetics of aerotolerant growth in an alphaproteobacterium with a naturally reduced genome. MBio. 2023;14(6). https:\/\/doi.org\/10.1128\/mbio.01487-23.","DOI":"10.1128\/mbio.01487-23"},{"key":"3059_CR12","doi-asserted-by":"crossref","unstructured":"Enright AL, Banta AB, Ward RD, Vazquez JR, Magdalena M, Wolfe MB, Teravest MA, Amador-noguez D, Jason M, Lansing E. (2023). The Genetics of Aerotolerant Growth in a Naturally Reduced Genome Alphaproteobacterium.","DOI":"10.1101\/2023.06.12.544693"},{"issue":"6","key":"3059_CR13","doi-asserted-by":"publisher","first-page":"e02441","DOI":"10.1128\/aem.02441-20","volume":"87","author":"K Fuchino","year":"2021","unstructured":"Fuchino K, Chan H, Hwang LC, Bruheim P. Ethanologenic bacterium Zymomonas mobilis divides asymmetrically and exhibits heterogeneity in DNA content. Appl Environ Microbiol. 2021;87(6):e02441\u201320. https:\/\/doi.org\/10.1128\/aem.02441-20.","journal-title":"Appl Environ Microbiol"},{"issue":"August","key":"3059_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmicb.2021.705895","volume":"12","author":"K Fuchino","year":"2021","unstructured":"Fuchino K, Wasser D, Soppa J. Genome Copy Number Quantification Revealed That the Ethanologenic Alpha-Proteobacterium Zymomonas mobilis Is Polyploid. Front Microbiol. 2021;12(August):1\u201312. https:\/\/doi.org\/10.3389\/fmicb.2021.705895.","journal-title":"Front Microbiol"},{"issue":"16","key":"3059_CR15","doi-asserted-by":"publisher","first-page":"3919","DOI":"10.1093\/nar\/9.16.3919","volume":"9","author":"NJ Gay","year":"1981","unstructured":"Gay NJ, Walker JE. Nucleic Acids Research The atp operon: nucleotide sequence of the promoter and the genes for the membrane proteins, and the 6 subunit of Escherichia coli ATP-synthase. Nucleic Acids Res. 1981;9(16):3919\u201326.","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"3059_CR16","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.jbiosc.2010.12.009","volume":"111","author":"T Hayashi","year":"2011","unstructured":"Hayashi T, Furuta Y, Furukawa K. Respiration-deficient mutants of Zymomonas mobilis show improved growth and ethanol fermentation under aerobic and high temperature conditions. J Biosci Bioeng. 2011;111(4):414\u20139. https:\/\/doi.org\/10.1016\/j.jbiosc.2010.12.009.","journal-title":"J Biosci Bioeng"},{"issue":"3","key":"3059_CR17","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1128\/JB.01016-10","volume":"193","author":"C Hildenbrand","year":"2011","unstructured":"Hildenbrand C, Stock T, Lange C, Rother M, Soppa J. Genome copy numbers and gene conversion in methanogenic archaea. J Bacteriol. 2011;193(3):734\u201343. https:\/\/doi.org\/10.1128\/JB.01016-10.","journal-title":"J Bacteriol"},{"key":"3059_CR18","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/BF00180626","volume":"35","author":"CW Jones","year":"1991","unstructured":"Jones CW, Doelle HW, Le L. Applied Microbiology Biotechnology Kinetic control of ethanol production by Zymomonas tnobilis. Appl Microbiol Biotechnol. 1991;35:4\u20139.","journal-title":"Appl Microbiol Biotechnol"},{"issue":"10","key":"3059_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/AEM.00193-19","volume":"85","author":"SE Jones-Burrage","year":"2019","unstructured":"Jones-Burrage SE, Kremer TA, McKinlay JB. Cell aggregation and aerobic respiration are important for Zymomonas mobilis ZM4 survival in an aerobic minimal medium. Appl Environ Microbiol. 2019;85(10):1\u201312. https:\/\/doi.org\/10.1128\/AEM.00193-19.","journal-title":"Appl Environ Microbiol"},{"issue":"SUPPL","key":"3059_CR20","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0065-2911(06)51002-1","volume":"51","author":"U Kalnenieks","year":"2006","unstructured":"Kalnenieks U. Physiology of Zymomonas mobilis: some unanswered questions. Adv Microb Physiol. 2006;51(SUPPL):73\u2013117. https:\/\/doi.org\/10.1016\/S0065-2911(06)51002-1.","journal-title":"Adv Microb Physiol"},{"key":"3059_CR21","doi-asserted-by":"publisher","first-page":"2533","DOI":"10.3389\/fmicb.2019.02533","volume":"10","author":"U Kalnenieks","year":"2019","unstructured":"Kalnenieks U, Balodite E, Str\u00e4hler S, Strazdina I, Rex J, Pentjuss A, Fuchino K, Bruheim P, Rutkis R, Pappas KM, Poole RK, Sawodny O, Bettenbrock K. Improvement of Acetaldehyde Production in Zymomonas mobilis by Engineering of Its Aerobic Metabolism. Front Microbiol. 2019;10:2533. https:\/\/doi.org\/10.3389\/fmicb.2019.02533.","journal-title":"Front Microbiol"},{"key":"3059_CR22","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1007\/BF00258148","volume":"160","author":"U Kalnenieks","year":"1993","unstructured":"Kalnenieks U, de Graaf AA, Bringer-Meyer S, Sahm H. Oxidative phosphorylation in Zymomonas mobilis. Arch Microbiol. 1993;160:74\u20139.","journal-title":"Arch Microbiol"},{"issue":"1","key":"3059_CR23","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S0378-1097(98)00424-8","volume":"168","author":"U Kalnenieks","year":"1998","unstructured":"Kalnenieks U, Galinina N, Bringer-Meyer S, Poole RK. Membrane D-lactate oxidase in Zymomonas mobilis: Evidence for a branched respiratory chain. FEMS Microbiol Lett. 1998;168(1):91\u20137. https:\/\/doi.org\/10.1016\/S0378-1097(98)00424-8.","journal-title":"FEMS Microbiol Lett"},{"key":"3059_CR24","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1099\/00221287-146-6-1259","volume":"146","author":"U Kalnenieks","year":"2000","unstructured":"Kalnenieks U, Galinina N, Toma MM, Poole RK. Cyanide inhibits respiration yet stimulates aerobic growth of Zymomonas mobilis. Microbiology. 2000;146:1259\u201366.","journal-title":"Microbiology"},{"issue":"2","key":"3059_CR25","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.bbabio.2011.10.006","volume":"1817","author":"A Koch-Koerfges","year":"2012","unstructured":"Koch-Koerfges A, Kabus A, Ochrombel I, Marin K, Bott M. Physiology and global gene expression of a Corynebacterium glutamicum \u2206f 1F O-ATP synthase mutant devoid of oxidative phosphorylation. Biochim et Biophys Acta - Bioenergetics. 2012;1817(2):370\u201380. https:\/\/doi.org\/10.1016\/j.bbabio.2011.10.006.","journal-title":"Biochim et Biophys Acta - Bioenergetics"},{"issue":"14","key":"3059_CR26","doi-asserted-by":"publisher","first-page":"3909","DOI":"10.1128\/JB.184.14.3909","volume":"184","author":"BJ Koebmann","year":"2002","unstructured":"Koebmann BJ, Westerhoff HV, Snoep JL, Nilsson D, Jensen PR. The Glycolytic Flux in Escherichia coli is controlled by the demand for ATP. J Bacteriol. 2002;184(14):3909\u201316. https:\/\/doi.org\/10.1128\/JB.184.14.3909.","journal-title":"J Bacteriol"},{"issue":"1\u20132","key":"3059_CR27","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1023\/A:1020398117281","volume":"29","author":"BJ Koebmann","year":"2002","unstructured":"Koebmann BJ, Westerhoff HV, Snoep JL, Solem C, Pedersen MB, Nilsson D, Michelsen O, Jensen PR. The extend to which ATP demand controls glycolytic flux depends strongly on the organism and conditions for growth. Mol Biol Rep. 2002;29(1\u20132):41\u20135.","journal-title":"Mol Biol Rep"},{"issue":"3","key":"3059_CR28","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1111\/j.1365-2958.2011.07600.x","volume":"80","author":"C Lange","year":"2011","unstructured":"Lange C, Zerulla K, Breuert S, Soppa J. Gene conversion results in the equalization of genome copies in the polyploid haloarchaeon Haloferax volcanii. Mol Microbiol. 2011a;80(3):666\u201377. https:\/\/doi.org\/10.1111\/j.1365-2958.2011.07600.x.","journal-title":"Mol Microbiol"},{"issue":"3","key":"3059_CR29","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1111\/j.1365-2958.2011.07600.x","volume":"80","author":"C Lange","year":"2011","unstructured":"Lange C, Zerulla K, Breuert S, Soppa J. Gene conversion results in the equalization of genome copies in the polyploid haloarchaeon Haloferax volcanii. Mol Microbiol. 2011b;80(3):666\u201377. https:\/\/doi.org\/10.1111\/j.1365-2958.2011.07600.x.","journal-title":"Mol Microbiol"},{"issue":"4","key":"3059_CR30","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1007\/BF00037050","volume":"17","author":"H Lill","year":"1991","unstructured":"Lill H, Nelson N. The atp1 and atp2 operons of the cyanobacterium Synechocystis sp. PCC 6803. Plant Mol Biol. 1991a;17(4):641\u201352. https:\/\/doi.org\/10.1007\/BF00037050.","journal-title":"Plant Mol Biol"},{"issue":"4","key":"3059_CR31","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1007\/BF00037050","volume":"17","author":"H Lill","year":"1991","unstructured":"Lill H, Nelson N. The atp1 and atp2 operons of the cyanobacterium Synechocystis sp. PCC 6803. Plant Mol Biol. 1991b;17(4):641\u201352. https:\/\/doi.org\/10.1007\/BF00037050.","journal-title":"Plant Mol Biol"},{"issue":"3","key":"3059_CR32","doi-asserted-by":"publisher","first-page":"132","DOI":"10.4236\/abb.2011.23021","volume":"2","author":"MJ Mahon","year":"2011","unstructured":"Mahon MJ. pHluorin2: an enhanced, ratiometric, pH-sensitive green florescent protein. Adv Bioscience Biotechnol. 2011;2(3):132\u20137. https:\/\/doi.org\/10.4236\/abb.2011.23021.","journal-title":"Adv Bioscience Biotechnol"},{"issue":"19","key":"3059_CR33","doi-asserted-by":"publisher","first-page":"6869","DOI":"10.1128\/JB.00452-06","volume":"188","author":"S Noda","year":"2006","unstructured":"Noda S, Takezawa Y, Mizutani T, Asakura T, Nishiumi E, Onoe K, Wada M, Tomita F, Matsushita K, Yokota A. Alterations of cellular physiology in Escherichia coli in response to oxidative phosphorylation impaired by defective F1-ATPase. J Bacteriol. 2006;188(19):6869\u201376. https:\/\/doi.org\/10.1128\/JB.00452-06.","journal-title":"J Bacteriol"},{"issue":"8","key":"3059_CR34","doi-asserted-by":"publisher","first-page":"0","DOI":"10.1128\/jb.169.8.3726-3736.1987","volume":"169","author":"YA Osman","year":"1987","unstructured":"Osman YA, Conway T, Bonetti SJ, Ingram L. Glycolytic Flux in Zymomonas mobilis: Enzyme and Metabolite Levels during Batch Fermentationt. J Bacteriol. 1987;169(8):0.","journal-title":"J Bacteriol"},{"issue":"6","key":"3059_CR35","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/BF00250417","volume":"28","author":"LM Pankova","year":"1988","unstructured":"Pankova LM, Shvinka JE, Beker MJ. Regulation of intracellular H+ balance in Zymomonas mobilis 113 during the shift from anaerobic to aerobic conditions. Appl Microbiol Biotechnol. 1988;28(6):583\u20138. https:\/\/doi.org\/10.1007\/BF00250417.","journal-title":"Appl Microbiol Biotechnol"},{"key":"3059_CR36","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/0005-2736(91)90207-O","volume":"1068","author":"L Reyes","year":"1991","unstructured":"Reyes L, Scopes R. Membrane-associated ATPase from Zymomonas mobilis; purification and characterization. Biochim Biophys Acta. 1991;1068:174\u20138.","journal-title":"Biochim Biophys Acta"},{"key":"3059_CR37","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1002\/bit.260260308","volume-title":"Microbial Reactions, Advances in Biochemical Engineering","author":"PL Rogers","year":"1982","unstructured":"Rogers PL, Lee KJ, Skotnicki ML, Tribe DE. Ethanol production by Zymomonas mobilis. Microbial Reactions, Advances in Biochemical Engineering. Volume 23. Berlin Heidelberg: Springer; 1982. pp. 37\u201384. https:\/\/doi.org\/10.1002\/bit.260260308."},{"issue":"9","key":"3059_CR38","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/j.bbabio.2015.02.005","volume":"1847","author":"T R\u00fchle","year":"2015","unstructured":"R\u00fchle T, Leister D. Assembly of F1F0-ATP synthases. Biochim et Biophys Acta - Bioenergetics. 2015a;1847(9):849\u201360. https:\/\/doi.org\/10.1016\/j.bbabio.2015.02.005.","journal-title":"Biochim et Biophys Acta - Bioenergetics"},{"issue":"9","key":"3059_CR39","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1016\/j.bbabio.2015.02.005","volume":"1847","author":"T R\u00fchle","year":"2015","unstructured":"R\u00fchle T, Leister D. Assembly of F1F0-ATP synthases. Biochim et Biophys Acta - Bioenergetics. 2015b;1847(9):849\u201360. https:\/\/doi.org\/10.1016\/j.bbabio.2015.02.005.","journal-title":"Biochim et Biophys Acta - Bioenergetics"},{"issue":"10","key":"3059_CR40","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1002\/jobm.201300859","volume":"54","author":"R Rutkis","year":"2014","unstructured":"Rutkis R, Galinina N, Strazdina I, Kalnenieks U. The inefficient aerobic energetics of Zymomonas mobilis: identifying the bottleneck. J Basic Microbiol. 2014;54(10):1090\u20137. https:\/\/doi.org\/10.1002\/jobm.201300859.","journal-title":"J Basic Microbiol"},{"issue":"12","key":"3059_CR41","doi-asserted-by":"publisher","first-page":"2674","DOI":"10.1099\/mic.0.071340-0","volume":"159","author":"R Rutkis","year":"2013","unstructured":"Rutkis R, Kalnenieks U, Stalidzans E, Fell DA. Kinetic modelling of the Zymomonas mobilis Entner-Doudoroff pathway: Insights into control and functionality. Microbiol (United Kingdom). 2013;159(12):2674\u201389. https:\/\/doi.org\/10.1099\/mic.0.071340-0.","journal-title":"Microbiol (United Kingdom)"},{"issue":"1","key":"3059_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13104-021-05625-5","volume":"14","author":"R Rutkis","year":"2021","unstructured":"Rutkis R, Strazdina I, Lasa Z, Bruheim P, Kalnenieks U. Ethanologenesis and respiration in a pyruvate decarboxylase-deficient Zymomonas mobilis. BMC Res Notes. 2021;14(1):1\u20136. https:\/\/doi.org\/10.1186\/s13104-021-05625-5.","journal-title":"BMC Res Notes"},{"issue":"1","key":"3059_CR43","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/nbt1045","volume":"23","author":"JS Seo","year":"2005","unstructured":"Seo JS, Chong H, Park HS, Yoon KO, Jung C, Kim JJ, Hong JH, Kim H, Kim JH, Kil J, Il, Park CJ, Oh HM, Lee JS, Jin SJ, Um HW, Lee HJ, Oh SJ, Kim JY, Kang HL, Kang HS. The genome sequence of the ethanologenic bacterium Zymomonas mobil is ZM4. Nat Biotechnol. 2005;23(1):63\u20138. https:\/\/doi.org\/10.1038\/nbt1045.","journal-title":"Nat Biotechnol"},{"issue":"4","key":"3059_CR44","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1159\/000112598","volume":"14","author":"K Sootsuwan","year":"2008","unstructured":"Sootsuwan K, Lertwattanasakul N, Thanonkeo P, Matsushita K, Yamada M. Analysis of the respiratory chain in ethanologenic Zymomonas mobilis with a cyanide-resistant bd-type ubiquinol oxidase as the only terminal oxidase and its possible physiological roles. J Mol Microbiol Biotechnol. 2008;14(4):163\u201375. https:\/\/doi.org\/10.1159\/000112598.","journal-title":"J Mol Microbiol Biotechnol"},{"issue":"5\u20136","key":"3059_CR45","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1159\/000368855","volume":"24","author":"J Soppa","year":"2014","unstructured":"Soppa J. Polyploidy in archaea and bacteria: About desiccation resistance, giant cell size, long-term survival, enforcement by a eukaryotic host and additional aspects. J Mol Microbiol Biotechnol. 2014;24(5\u20136):409\u201319. https:\/\/doi.org\/10.1159\/000368855.","journal-title":"J Mol Microbiol Biotechnol"},{"issue":"1","key":"3059_CR46","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/0304-4173(73)90012-8","volume":"301","author":"AH Stouthamer","year":"1973","unstructured":"Stouthamer AH, Bettenhaussen C. Utilization of energy for growth and maintenance in continuous and batch cultures of microorganisms. A reevaluation of the method for the determination of ATP production by measuring molar growth yields. BBA Reviews Bioenergetics. 1973;301(1):53\u201370. https:\/\/doi.org\/10.1016\/0304-4173(73)90012-8.","journal-title":"BBA Reviews Bioenergetics"},{"key":"3059_CR47","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/BF00492023","volume":"113","author":"AH Stouthamer","year":"1977","unstructured":"Stouthamer AH, Bettenhaussen CW. A Continuous Culture Study of an ATPase-Negative Mutant of Escherichia coli. Arch Microbiol. 1977;113:185\u20139.","journal-title":"Arch Microbiol"},{"issue":"11","key":"3059_CR48","doi-asserted-by":"publisher","first-page":"951","DOI":"10.3390\/fermentation9110951","volume":"9","author":"I Strazdina","year":"2023","unstructured":"Strazdina I, Bikerniece M, Paegle ER, Shvirksts K, Grube M, Lasa Z, Rutkis R, Kalnenieks U. Oxidative Phosphorylation for Aerobic Survival, but Not for Growth: The Peculiar \u2018Make-Accumulate-Consume\u2019 Strategy in Zymomonas mobilis. Fermentation. 2023;9(11):951. https:\/\/doi.org\/10.3390\/fermentation9110951.","journal-title":"Fermentation"},{"issue":"6","key":"3059_CR49","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1007\/BF00248833","volume":"154","author":"M Strohdeicher","year":"1990","unstructured":"Strohdeicher M, Neuss B, Bringer-Meyer S, Sahm H. Electron transport chain of Zymomonas mobilis. Arch Microbiol. 1990;154(6):536\u201343. https:\/\/doi.org\/10.1007\/BF00248833.","journal-title":"Arch Microbiol"},{"issue":"1","key":"3059_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/mmbr.41.1.1-46.1977","volume":"41","author":"J Swings","year":"1977","unstructured":"Swings J, De Ley J. The biology of Zymomonas. Bacteriological Reviews. 1977;41(1):1\u201346. https:\/\/doi.org\/10.1128\/mmbr.41.1.1-46.1977.","journal-title":"Bacteriological Reviews"},{"issue":"2","key":"3059_CR51","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1111\/j.1574-6968.2009.01556.x","volume":"294","author":"S Thoma","year":"2009","unstructured":"Thoma S, Schobert M. An improved escherichia coli donor strain for diparental mating. FEMS Microbiol Lett. 2009;294(2):127\u201332. https:\/\/doi.org\/10.1111\/j.1574-6968.2009.01556.x.","journal-title":"FEMS Microbiol Lett"}],"container-title":["Microbial Cell Factories"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12934-026-03059-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12934-026-03059-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12934-026-03059-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:36:31Z","timestamp":1787121391000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12934-026-03059-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":51,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["3059"],"URL":"https:\/\/doi.org\/10.1186\/s12934-026-03059-x","relation":{},"ISSN":["1475-2859"],"issn-type":[{"value":"1475-2859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,13]]},"assertion":[{"value":"31 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2026","order":6,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":7,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original online version of this article was revised due to update in the funding statement.","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"161"}}