{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:42:53Z","timestamp":1787791373865,"version":"build-2784847793"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T00:00:00Z","timestamp":1564358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T00:00:00Z","timestamp":1564358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institute for Communicable Diseases"},{"name":"CDC\/GDD","award":["U19GH000622-01 MAL01"],"award-info":[{"award-number":["U19GH000622-01 MAL01"]}]},{"name":"DST\/NRF South African Research Chair Initiative"},{"DOI":"10.13039\/501100004493","name":"International Atomic Energy Agency","doi-asserted-by":"crossref","award":["Research Contract No. 17904"],"award-info":[{"award-number":["Research Contract No. 17904"]}],"id":[{"id":"10.13039\/501100004493","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004493","name":"International Atomic Energy Agency","doi-asserted-by":"crossref","award":["19099"],"award-info":[{"award-number":["19099"]}],"id":[{"id":"10.13039\/501100004493","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004493","name":"International Atomic Energy Agency","doi-asserted-by":"crossref","award":["SAF 5013\/5014"],"award-info":[{"award-number":["SAF 5013\/5014"]}],"id":[{"id":"10.13039\/501100004493","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004493","name":"International Atomic Energy Agency","doi-asserted-by":"crossref","award":["19099"],"award-info":[{"award-number":["19099"]}],"id":[{"id":"10.13039\/501100004493","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004493","name":"International Atomic Energy Agency","doi-asserted-by":"crossref","award":["SAF 5013\/5014"],"award-info":[{"award-number":["SAF 5013\/5014"]}],"id":[{"id":"10.13039\/501100004493","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Industrial Development Corporation"},{"name":"South African Nuclear Energy Corporation (NECSA) through its Nuclear Technologies in Medicine Biosciences Initiative"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Malar J"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12936-019-2889-5","type":"journal-article","created":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T14:03:34Z","timestamp":1564409014000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Anopheles parensis contributes to residual malaria transmission in South Africa"],"prefix":"10.1186","volume":"18","author":[{"given":"Ashley","family":"Burke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Dahan-Moss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Duncan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bheki","family":"Qwabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Coetzee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizette","family":"Koekemoer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8857-1304","authenticated-orcid":false,"given":"Basil","family":"Brooke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,7,29]]},"reference":[{"issue":"10 Suppl 2","key":"2889_CR1","doi-asserted-by":"publisher","first-page":"779","DOI":"10.7196\/SAMJ.7441","volume":"103","author":"R Maharaj","year":"2013","unstructured":"Maharaj R, Raman J, Morris N, Moonasar D, Durrheim DN, Seocharan I, et al. Epidemiology of malaria in South Africa: from control to elimination. S Afr Med J. 2013;103(10 Suppl 2):779\u201383.","journal-title":"S Afr Med J"},{"key":"2889_CR2","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1186\/s12936-016-1497-x","volume":"15","author":"J Raman","year":"2016","unstructured":"Raman J, Morris N, Frean J, Brooke B, Blumberg L, Kruger P, et al. Reviewing South Africa\u2019s malaria elimination strategy (2012\u20132018): progress, challenges and priorities. Malar J. 2016;15:438.","journal-title":"Malar J."},{"key":"2889_CR3","volume-title":"World malaria report","author":"World Health Organization","year":"2018","unstructured":"World Health Organization. World malaria report. Geneva: World Health Organization; 2018."},{"key":"2889_CR4","first-page":"1","volume":"6","author":"R Christian","year":"2018","unstructured":"Christian R, Dahan-Moss Y, Braack L, Munhenga G, Kaiser M, Lobb L, et al. Malaria vector surveillance report, South Africa, January\u2013December, 2017. NICD Bulletin. 2018;6:1.","journal-title":"NICD Bulletin."},{"key":"2889_CR5","doi-asserted-by":"publisher","first-page":"784","DOI":"10.7196\/SAMJ.7447","volume":"103","author":"BD Brooke","year":"2013","unstructured":"Brooke BD, Koekemoer L, Kruger P, Urbach J, Misiani E, Coetzee M. Malaria vector control in South Africa. S Afr Med J. 2013;103:784\u20138.","journal-title":"S Afr Med J"},{"key":"2889_CR6","doi-asserted-by":"publisher","first-page":"246","DOI":"10.11646\/zootaxa.3619.3.2","volume":"3619","author":"M Coetzee","year":"2013","unstructured":"Coetzee M, Hunt RH, Wilkerson R, Della Torre A, Coulibaly MB, Besanksky NJ. Anopheles coluzzii and Anopheles amharicus, new members of the Anopheles gambiae complex. Zootaxa. 2013;3619:246.","journal-title":"Zootaxa"},{"issue":"6","key":"2889_CR7","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1093\/jme\/tjx169","volume":"54","author":"LC Dandalo","year":"2017","unstructured":"Dandalo LC, Brooke BD, Munhenga G, Lobb LN, Zikhali J, Ngxongo SP, et al. Population dynamics and Plasmodium falciparum (Haemosporida: Plasmodiidae) infectivity rates for the malaria vector Anopheles arabiensis (Diptera: Culicidae) at Mamfene, KwaZulu-Natal. J Med Entomol. 2017;54(6):1758\u201366.","journal-title":"J Med Entomol."},{"key":"2889_CR8","first-page":"157","volume":"46","author":"N Cuamba","year":"2009","unstructured":"Cuamba N, Mendis C. The role of Anopheles merus in malaria transmission in an area of southern Mozambique. J Vector Borne Dis. 2009;46:157\u20139.","journal-title":"J Vector Borne Dis."},{"issue":"Suppl 1","key":"2889_CR9","doi-asserted-by":"publisher","first-page":"S39","DOI":"10.5588\/pha.17.0034","volume":"8","author":"F Mbokazi","year":"2018","unstructured":"Mbokazi F, Coetzee M, Brooke B, Govere J, Reid A, Owiti P, et al. Changing distribution and abundance of the malaria vector Anopheles merus in Mpumalanga Province, South Africa. Public Health Action. 2018;8(Suppl 1):S39\u201343.","journal-title":"Public Health Action."},{"key":"2889_CR10","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/S0169-4758(99)01563-X","volume":"16","author":"M Coetzee","year":"2000","unstructured":"Coetzee M, Craig M, Le Sueur D. Distribution of African malaria mosquitoes belonging to the Anopheles gambiae complex. Parasitol Today. 2000;16:74\u20137.","journal-title":"Parasitol Today."},{"key":"2889_CR11","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1146\/annurev-ento-120811-153628","volume":"58","author":"M Coetzee","year":"2013","unstructured":"Coetzee M, Koekemoer LL. Molecular systematics and insecticide resistance in the major African malaria vector Anopheles funestus. Annu Rev Entomol. 2013;58:393\u2013412.","journal-title":"Annu Rev Entomol"},{"key":"2889_CR12","doi-asserted-by":"publisher","first-page":"43779","DOI":"10.1038\/srep43779","volume":"7","author":"A Burke","year":"2017","unstructured":"Burke A, Dandalo L, Munhenga G, Dahan-Moss Y, Mbokazi F, Ngxongo S, et al. A new malaria vector mosquito in South Africa. Sci Rep. 2017;7:43779.","journal-title":"Sci Rep."},{"key":"2889_CR13","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1111\/j.1365-2915.1996.tb00092.x","volume":"10","author":"TJ Wilkes","year":"1996","unstructured":"Wilkes TJ, Matola YG, Charlwood JD. Anopheles rivulorum, a vector of human malaria in Africa. Med Vet Entomol. 1996;10:108\u201310.","journal-title":"Med Vet Entomol"},{"key":"2889_CR14","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.actatropica.2007.04.009","volume":"102","author":"EA Temu","year":"2007","unstructured":"Temu EA, Minjas JN, Tuno N, Kawada H, Takagi M. Identification of four members of the Anopheles funestus (Diptera: Culicidae) group and their role in Plasmodium falciparum transmission in Bagamoyo coastal Tanzania. Acta Trop. 2007;102:119\u201325.","journal-title":"Acta Trop"},{"key":"2889_CR15","doi-asserted-by":"publisher","first-page":"57","DOI":"10.12688\/wellcomeopenres.12187.1","volume":"2","author":"D Kyalo","year":"2017","unstructured":"Kyalo D, Amratia P, Mundia CW, Mbogo CM, Coetzee M, Snow RW. A geo-coded inventory of anophelines in the Afrotropical Region south of the Sahara: 1898\u20132016. Wellcome Open Res. 2017;2:57.","journal-title":"Wellcome Open Res."},{"key":"2889_CR16","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1186\/1756-3305-5-230","volume":"5","author":"H Kawada","year":"2012","unstructured":"Kawada H, Dida GO, Sonye G, Njenga SM, Mwandawiro C, Minakawa N. Reconsideration of\u00a0Anopheles rivulorum\u00a0as a vector of\u00a0Plasmodium falciparum\u00a0in western Kenya: some evidence from biting time, blood preference, sporozoite positive rate, and pyrethroid resistance. Parasit Vectors. 2012;5:230.","journal-title":"Parasit Vectors."},{"key":"2889_CR17","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1186\/s13071-018-3171-3","volume":"11","author":"EO Ogola","year":"2018","unstructured":"Ogola EO, Fillinger U, Ondiba IM, Villinger J, Masiga DK, Torto B, et al. Insights into malaria transmission among Anopheles funestus mosquitoes, Kenya. Parasit Vectors. 2018;11:577.","journal-title":"Parasit Vectors."},{"key":"2889_CR18","first-page":"130","volume":"19","author":"L Kamau","year":"2003","unstructured":"Kamau L, Koekemoer LL, Hunt RH, Coetzee M. Anopheles parensis: the main member of the Anopheles funestus species group found resting inside human dwellings in Mwea area of central Kenya toward the end of the rainy season. J Am Mosq Control Assoc. 2003;19:130\u20133.","journal-title":"J Am Mosq Control Assoc."},{"key":"2889_CR19","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1475-2875-6-30","volume":"6","author":"JC Mouatcho","year":"2007","unstructured":"Mouatcho JC, Hargreaves K, Koekemoer LL, Brooke BD, Oliver SV, Hunt RH, et al. Indoor collections of the Anopheles funestus group (Diptera: Culicidae) in sprayed houses in northern KwaZulu-Natal, South Africa. Malar J. 2007;6:30.","journal-title":"Malar J."},{"key":"2889_CR20","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/1756-3305-7-71","volume":"7","author":"JC Mulamba","year":"2014","unstructured":"Mulamba JC, Hargreaves K, Koekemoer LL, Brooke BD, Oliver SV, Hunt RH, et al. Contrasting Plasmodium infection rates and insecticide susceptibility profiles between the sympatric sibling species Anopheles parensis and Anopheles funestus s.s.: a potential challenge for malaria vector control in Uganda. Parasit Vectors. 2014;7:71.","journal-title":"Parasit Vectors."},{"key":"2889_CR21","volume-title":"A supplement to the Anophelinae of Africa South of the Sahara (Afrotropical region)","author":"MT Gillies","year":"1987","unstructured":"Gillies MT, Coetzee M. A supplement to the Anophelinae of Africa South of the Sahara (Afrotropical region). Johannesburg: South African Institute for Medical Research; 1987."},{"key":"2889_CR22","doi-asserted-by":"publisher","first-page":"520","DOI":"10.4269\/ajtmh.1993.49.520","volume":"49","author":"JA Scott","year":"1993","unstructured":"Scott JA, Brogdon WG, Collins FH. Identification of single specimens of the Anopheles gambiae complex by the polymerase chain reaction. Am J Trop Med Hyg. 1993;49:520\u20139.","journal-title":"Am J Trop Med Hyg"},{"key":"2889_CR23","doi-asserted-by":"publisher","first-page":"804","DOI":"10.4269\/ajtmh.2002.66.804","volume":"6","author":"LL Koekemoer","year":"2002","unstructured":"Koekemoer LL, Kamau L, Hunt RH, Coetzee M. A cocktail polymerase chain reaction assay to identify members of the Anopheles funestus (diptera: culicidae) group. Am J Trop Med Hyg. 2002;6:804\u201311.","journal-title":"Am J Trop Med Hyg"},{"key":"2889_CR24","doi-asserted-by":"publisher","first-page":"200","DOI":"10.4269\/ajtmh.2003.69.200","volume":"69","author":"A Cohuet","year":"2003","unstructured":"Cohuet A, Simard F, Toto JC, Kengne P, Coetzee M, Fontenille D. Species identification within the Anopheles funestus group of malaria vectors in Cameroon and evidence for a new species. Am J Trop Med Hyg. 2003;69:200\u20135.","journal-title":"Am J Trop Med Hyg"},{"key":"2889_CR25","first-page":"39","volume":"65","author":"RA Wirtz","year":"1987","unstructured":"Wirtz RA, Zavala F, Charoenvit Y, Campbell GH, Burkot TR, Schneider I, et al. Comparative testing of monoclonal antibodies against Plasmodium falciparum sporozoites for ELISA development. Bull World Health Organ. 1987;65:39\u201345.","journal-title":"Bull World Health Organ."},{"key":"2889_CR26","doi-asserted-by":"publisher","first-page":"783","DOI":"10.4269\/ajtmh.1984.33.783","volume":"33","author":"TR Burkot","year":"1984","unstructured":"Burkot TR, Williams JL, Schneider I. Identification of Plasmodium falciparum-infected mosquitoes by a double antibody enzyme-linked immunosorbent assay. Am J Trop Med Hyg. 1984;33:783\u20138.","journal-title":"Am J Trop Med Hyg"},{"key":"2889_CR27","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1186\/1475-2875-10-195","volume":"10","author":"L Durnez","year":"2011","unstructured":"Durnez L, Van Bortel W, Denis L, Roelants P, Veracx A, Trung HD, et al. False positive circumsporozoite protein ELISA: a challenge for the estimation of the entomological inoculation rate of malaria and for vector incrimination. Malar J. 2011;10:195.","journal-title":"Malar J."},{"key":"2889_CR28","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/0166-6851(93)90077-B","volume":"6","author":"G Snounou","year":"1993","unstructured":"Snounou G, Viriyakosol S, Zhu XP, Jarra W, Pinheiro L, Rosario VE, et al. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol. 1993;6:315\u201320.","journal-title":"Mol Biochem Parasitol."},{"key":"2889_CR29","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/jvec.12128","volume":"40","author":"LC Norris","year":"2015","unstructured":"Norris LC, Norris DE. Phylogeny of anopheline (Diptera: Culicidae) species in southern Africa, based on nuclear and mitochondrial genes. J Vector Ecol. 2015;40:16\u201327.","journal-title":"J Vector Ecol."},{"key":"2889_CR30","doi-asserted-by":"publisher","first-page":"e103262","DOI":"10.1371\/journal.pone.0103262","volume":"9","author":"HG Ngassa Mbenda","year":"2014","unstructured":"Ngassa Mbenda HG, Das A. Molecular evidence of Plasmodium vivax mono and mixed malaria parasite infections in Duffy-negative native Cameroonians. PLoS One. 2014;9:e103262.","journal-title":"PLoS One."},{"key":"2889_CR31","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s12936-018-2189-5","volume":"17","author":"E Erlank","year":"2018","unstructured":"Erlank E, Koekemoer LL, Coetzee M. The importance of morphological identification of African anopheline mosquitoes (Diptera: Culicidae) for malaria control programmes. Malar J. 2018;17:43.","journal-title":"Malar J."},{"key":"2889_CR32","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1186\/1475-2875-7-177","volume":"7","author":"C Bass","year":"2008","unstructured":"Bass C, Nikou D, Blagborough AM, Vontas J, Sinden RE, Martin S, Williamson MS, et al. PCR-based detection of Plasmodium in Anopheles mosquitoes: a comparison of a new high-throughput assay with existing methods. Malar J. 2008;7:177.","journal-title":"Malar J."},{"key":"2889_CR33","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1038\/s41598-018-19780-6","volume":"8","author":"M Kefi","year":"2018","unstructured":"Kefi M, Mavridis K, Sim\u00f5es ML, Dimopoulos G, Siden-Kiamos I, Vontas J. New rapid one-step PCR diagnostic assay for Plasmodium falciparum infective mosquitoes. Sci Rep. 2018;8:1462.","journal-title":"Sci Rep."},{"key":"2889_CR34","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1007\/s00436-009-1543-5","volume":"105","author":"EJ Muturi","year":"2009","unstructured":"Muturi EJ, Kamau L, Jacob BG, Muriu S, Mbogo CM, Shililu J, et al. Spatial distribution, blood feeding pattern, and role of Anopheles funestus complex in malaria transmission in central Kenya. Parasitol Res. 2009;105:1041\u20136.","journal-title":"Parasitol Res"},{"key":"2889_CR35","volume-title":"The Anophelinae of Africa south of the Sahara (Ethiopian zoogeographical region)","author":"MT Gillies","year":"1968","unstructured":"Gillies MT, De Meillon B. The Anophelinae of Africa south of the Sahara (Ethiopian zoogeographical region). Johannesburg: South African Institute for Medical Research; 1968."},{"key":"2889_CR36","doi-asserted-by":"publisher","first-page":"46","DOI":"10.4314\/thrb.v10i1.14341","volume":"10","author":"EJ Kweka","year":"2008","unstructured":"Kweka EJ, Mahande AM, Nkya WM, Assenga C, Lyatuu EE, Nyale E, et al. Vector species composition and malaria infectivity rates in Mkuzi, Muheza District, north-eastern Tanzania. Tanzan J Health Res. 2008;10:46\u20139.","journal-title":"Tanzan J Health Res."},{"key":"2889_CR37","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1603\/0022-2585-40.5.664","volume":"40","author":"L Kamau","year":"2003","unstructured":"Kamau L, Munyekenye GO, Koekemoer LL, Hunt RH, Coetzee M. A survey of the Anopheles funestus (Diptera: Culicidae) group of mosquitoes from 10 sites in Kenya with special emphasis on population genetic structure based on chromosomal inversion karyotypes. J Med Entomol. 2003;40:664\u201371.","journal-title":"J Med Entomol"},{"key":"2889_CR38","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/1756-3305-5-69","volume":"5","author":"ME Sinka","year":"2012","unstructured":"Sinka ME, Bangs MJ, Manguin S, Rubio-Palis Y, Chareonviriyaphap T, Coetzee M, et al. A global map of dominant malaria vectors. Parasit Vectors. 2012;5:69.","journal-title":"Parasit Vectors."},{"key":"2889_CR39","first-page":"95","volume":"41","author":"TA Hall","year":"1999","unstructured":"Hall TA. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT. Nucleic Acids Symp Ser. 1999;41:95\u20138.","journal-title":"Nucleic Acids Symp Ser"}],"container-title":["Malaria Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12936-019-2889-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12936-019-2889-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12936-019-2889-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T23:20:11Z","timestamp":1595892011000},"score":1,"resource":{"primary":{"URL":"https:\/\/malariajournal.biomedcentral.com\/articles\/10.1186\/s12936-019-2889-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,29]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["2889"],"URL":"https:\/\/doi.org\/10.1186\/s12936-019-2889-5","relation":{},"ISSN":["1475-2875"],"issn-type":[{"value":"1475-2875","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,29]]},"assertion":[{"value":"13 May 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"An ethics approval waiver was obtained from the animal ethics screening committee of the University of the Witwatersrand, Johannesburg, South Africa. Reference: A Burke Waiver (2) 24-02-2017-O. Informed consent was obtained from all home-owners affected by the surveillance portion of this study.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"257"}}