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Microbiological control might be able to make a greater contribution to vector control in the future. The interactions between bacteria and mosquito make mosquito microbiota really promising from a disease control perspective. Here, the impact of\n                      <jats:italic>Chromobacterium violaceum<\/jats:italic>\n                      infections, isolated from both larvae and adult of wild-caught\n                      <jats:italic>Anopheles gambiae<\/jats:italic>\n                      sensu lato mosquitoes in Burkina Faso, was evaluated on mosquito survival, blood feeding and fecundity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      To assess entomopathogenic effects of\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      infection on mosquitoes, three different types of bioassays were performed in laboratory. These bioassays aimed to evaluate the impact of\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      infection on mosquito survival, blood feeding and fecundity, respectively. During bioassays mosquitoes were infected through the well-established system of cotton ball soaked with 6% glucose containing\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Chromobacterium violaceum<\/jats:italic>\n                      kills pyrethroid resistant\n                      <jats:italic>Anopheles coluzzii<\/jats:italic>\n                      (LT80 of 8.78\u00a0days\u2009\u00b1\u20090.18 at 10\n                      <jats:sup>8<\/jats:sup>\n                      bacteria cell\/ml of sugar meal). Interestingly, this bacterium had other negative effects on mosquito lifespan by significantly reducing (~\u200959%, P\u2009&lt;\u20090.001) the mosquito feeding willingness from day 4-post infection (~\u200981% would seek a host to blood feed) to 9- day post infection (22\u2009\u00b1\u20094.62% would seek a host to blood feed). Moreover,\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      considerably jeopardized the egg laying (~\u200916 eggs laid\/mosquito with\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      infected mosquitoes\n                      <jats:italic>vs<\/jats:italic>\n                      \u2009~\u2009129 eggs laid\/mosquito with control mosquitoes) and hatching of mosquitoes (a reduction of\u2009~\u200922% of hatching rate with\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      infected mosquitoes). Compared to the bacterial uninfected mosquitoes, mosquitoes infected with\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      showed significantly higher retention rates of immature eggs and follicles.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      These data showed important properties of\u00a0Burkina Faso\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      strains, which are highly virulent against insecticide-resistant\n                      <jats:italic>An. coluzzii<\/jats:italic>\n                      , and reduce both mosquito blood feeding and fecundity propensities. However, additional studies as the sequencing of\n                      <jats:italic>C. violaceum<\/jats:italic>\n                      genome and the potential toxins secreted will provide useful information render it a potential candidate for the biological control strategies of malaria and other disease vectors.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12936-020-03420-4","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T06:02:58Z","timestamp":1601618578000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Infection\u00a0of highly insecticide-resistant malaria vector Anopheles coluzzii with entomopathogenic bacteria Chromobacterium violaceum reduces its survival, blood feeding propensity and fecundity"],"prefix":"10.1186","volume":"19","author":[{"given":"Edounou Jacques","family":"Gnambani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2350-9339","authenticated-orcid":false,"given":"Etienne","family":"Bilgo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adama","family":"Sanou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roch K.","family":"Dabir\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulaye","family":"Diabat\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,2]]},"reference":[{"key":"3420_CR1","volume-title":"World Malaria Report 2017","author":"WHO","year":"2017","unstructured":"WHO. 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