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The current incidence rate is 0.74\u2030 inhabitants, and <jats:italic>Plasmodium vivax<\/jats:italic> is widely predominating even though <jats:italic>Plasmodium falciparum<\/jats:italic> is still present due to imported cases mainly from Africa. In FG, rapid diagnostic test (SD Malaria Ag P.f\/Pan\u00ae) is based on the detection of pan-pLDH, PfHRP2, and PfHRP3 antigens, while in South America, the share of deletion of PfHRP2 gene is significantly increasing. Accordingly, the study questions the reliability of RDTs in the Amazonian context.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The study is retrospective. It is conducted over 4\u00a0years and analysed 12,880 rapid diagnostic tests (RDTs) compared to concomitant Blood Film Tests (BFTs) sampled for malaria diagnosis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The global assessment of the accuracy of SD Malaria Ag P.f\/Pan\u00ae in the diagnostic of malaria shows both Positive and Negative Predictive Values (PPV and NPV) higher than 95%, except for PPV in the diagnosis of malaria to <jats:italic>P. falciparum<\/jats:italic> (88%). Overall, the concordance rate between RDT and BFT (positive\/positive; negative\/negative) was 99.5%. The PPV of the RDT in the follow-up of patients diagnosed with <jats:italic>P. falciparum<\/jats:italic> was the lowest during the first 28\u00a0days. The PPV of the RDT in the follow-up of patients diagnosed with <jats:italic>P. vivax<\/jats:italic> was the lowest during the first 21\u00a0days. The global sensitivity of SD Malaria Ag P.f\/Pan\u00ae test was, on average, 96% (88.2\u2013100) for <jats:italic>P. falciparum<\/jats:italic> and 93% (90.6\u201394.2) for <jats:italic>P. vivax<\/jats:italic>. The global specificity was 99.8% (99.5\u2013100) for all included species.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>SD Malaria Ag P.f\/Pan\u00ae is a reliable rapid test used for the first-line diagnosis in remote healthcare centres. The test results should be interpreted in the light of patient\u2019s recent medical history and the date of arrival to FG.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12936-021-03902-z","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T09:06:09Z","timestamp":1631869569000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Accuracy of SD Malaria Ag P.f\/Pan\u00ae as a rapid diagnostic test in French Amazonia"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8146-3362","authenticated-orcid":false,"given":"Jean Marc","family":"Pujo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Houcke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Lemmonier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Portecop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Fr\u00e9mery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Blanchet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Djossou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatem","family":"Kallel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magalie","family":"Demar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"3902_CR1","unstructured":"WHO. 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Our database has been registered at the Commission National de l'Informatique et des Libert\u00e9s (registration no 2219819), in compliance with French law on electronic data sources.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"At admission to our hospital, an information booklet was distributed to all patients or their relatives stating that their data can be used for research and publication purposes and that they can object to that. No person was unconsented.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"369"}}