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Moreover, anaemia-related studies were more concentrated in easily accessible areas. This study aimed to assess the prevalence of malaria and anaemia and corresponding risk factors among SAC in Dara Mallo and Uba Debretshay districts, in hard to reach areas, so as to inform appropriate integrated interventions for both diseases.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This study was part of baseline data collected for a cluster-randomized trial registered in Pan African Clinical Trials Registry (PACTR202001837195738). Data were collected from 2167 SAC and their households through face-to-face interview; malaria was diagnosed by using rapid diagnostic test (RDT); haemoglobin concentration was determined using hemoCue hb 301 and adjusted for altitude to determine anaemic status; helminth infections were determined by using kato-katz, and anthropometric measurements were made to determine nutritional status of children. Generalized mixed effects logistic regression model was used to assess the association between predictor variables and malaria and anaemia using school as a random variable.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The overall prevalence of malaria was 1.62% (95% CI 1.15\u20132.27%) (35\/2167). Of the 35 children positive for malaria, 20 (57.14%), 3 (8.57%) and 12 (34.29%) were due to <jats:italic>Plasmodium falciparum<\/jats:italic>, <jats:italic>Plasmodium vivax<\/jats:italic> and mixed infections of <jats:italic>P. falciparum<\/jats:italic> and <jats:italic>P. vivax,<\/jats:italic> respectively. Malaria was significantly lower among children from literate household head (Adjusted OR\u2009 = \u20090.38; 95% CI 0.15\u20130.95) and residence house located at an altitude range above 1100\u00a0masl (AOR\u2009 = \u20090.40; 95% CI 0.17\u20130.94). The prevalence of anaemia was 22.00% (95% CI 20.3\u201323.8%) (477\/2167) and was significantly reduced by eating legumes, nuts or seed group of food in their 24-h dietary diversity recall (AOR \u2009= \u20090.64; 95% CI 0.41\u20130.99).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The prevalence of malaria was low and unevenly distributed per school while the overall prevalence of anaemia was moderate. It is important to implement integrated interventions targeting both malaria and anaemia, with special emphasis given to children from illiterate households and living at an altitude below 1100\u00a0masl. The micronutrient content of locally grown legumes should be further investigated to recommend specific interventions to overcome anaemia.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12936-021-03937-2","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T06:31:33Z","timestamp":1634106693000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence and associated risk factors of asymptomatic malaria and anaemia among school-aged children in Dara Mallo and Uba Debretsehay districts: results from baseline cluster randomized trial"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6509-4672","authenticated-orcid":false,"given":"Zerihun","family":"Zerdo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilde","family":"Bastiaens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibyl","family":"Anthierens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fekadu","family":"Massebo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matewos","family":"Masne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gelila","family":"Biresaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misgun","family":"Shewangizaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abayneh","family":"Tunje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilma","family":"Chisha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsegaye","family":"Yohannes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Van Geertruyden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,13]]},"reference":[{"key":"3937_CR1","unstructured":"WHO. 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Official permission letter to conduct the research was submitted to district health offices and education offices in Dara Mallo and Uba Debretsehay districts. Support letters written by the respective education offices were given to each participating school and written consent was obtained from school head teachers. Parents of the selected SAC were invited to come to the schools and written consent was obtained before data collection at school and household level, which was documented in College of Medicine and Health Sciences, Arba Minch University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that we have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"400"}}