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Of Odisha","award":["DHS:2244\/DAMaN\/Project proposal\/18- 19\/31.12.2018"],"award-info":[{"award-number":["DHS:2244\/DAMaN\/Project proposal\/18- 19\/31.12.2018"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Malar J"],"published-print":{"date-parts":[[2021,12]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Information on the foci of\n Plasmodium<\/jats:italic>\n species infections is essential for any country heading towards elimination. Odisha, one of the malaria-endemic states of India is targeting elimination of malaria by 2030. To support decision-making regarding targeted intervention, the distribution of\n Plasmodium<\/jats:italic>\n species infections was investigated in hard-to-reach areas where a special malaria elimination drive, namely\n Durgama Anchalare Malaria Nirakaran<\/jats:italic>\n (DAMaN) began in 2017.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A cross-sectional survey was conducted in 2228 households during July to November 2019 in six districts, to evaluate the occurrence of\n Plasmodium<\/jats:italic>\n species. The species were identified by polymerase chain reaction (PCR) followed by sequencing, in case of\n Plasmodium ovale<\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of the 3557 blood specimens tested, malaria infection was detected in 282 (7.8%) specimens by PCR. Of the total positive samples, 14.1% were\n P.<\/jats:italic>\n \u00a0\n ovale<\/jats:italic>\n spp. and 10.3% were\n Plasmodium malariae<\/jats:italic>\n infections. The majority of\n P.<\/jats:italic>\n \u00a0\n ovale<\/jats:italic>\n spp. (75.8%) infections were mixed with either\n Plasmodium falciparum<\/jats:italic>\n and\/or\n Plasmodium vivax<\/jats:italic>\n and found to be distributed in three geophysical regions (Northern-plateau, Central Tableland and Eastern Ghat) of the State, while\n P. malariae<\/jats:italic>\n has been found in Northern-plateau and Eastern Ghat regions. Speciation revealed occurrence of both\n Plasmodium<\/jats:italic>\n \u00a0\n ovale curtisi<\/jats:italic>\n (classic type) and\n Plasmodium\u00a0ovale wallikeri<\/jats:italic>\n (variant type).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n In the present study a considerable number of\n P.\u00a0ovale<\/jats:italic>\n spp. and\n P. malariae<\/jats:italic>\n were detected in a wide geographical areas of Odisha State, which contributes around 40% of the country\u2019s total malaria burden. For successful elimination of malaria within the framework of national programme,\n P.\u00a0ovale<\/jats:italic>\n spp. along with\n P. malariae<\/jats:italic>\n needs to be incorporated in surveillance system, especially when\n P. falciparum<\/jats:italic>\n and\n P. vivax<\/jats:italic>\n spp. are in rapid decline.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1186\/s12936-021-04010-8","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T14:02:55Z","timestamp":1640268175000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Neglected malaria parasites in hard-to-reach areas of Odisha, India: implications in elimination programme"],"prefix":"10.1186","volume":"20","author":[{"given":"Madhusmita","family":"Bal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakanta","family":"Rana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arundhuti","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemant Kumar","family":"Khuntia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilam","family":"Somalkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niranjan","family":"Sahoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyoti","family":"Ghosal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghamitra","family":"Pati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambarish","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8415-6701","authenticated-orcid":false,"given":"Manoranjan","family":"Ranjit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,23]]},"reference":[{"key":"4010_CR1","unstructured":"WHO. 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Informed consent was obtained from all the participants aged\u2009>\u200918\u00a0years and assent was obtained for the participants aged 5\u201317\u00a0years in addition to parental consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"482"}}