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Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the assessment of such patients\u2019 state employing future generation computers extended with advanced human\u2013machine interfaces.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>First, the hearing abilities of 33 participants in the state of coma were evaluated using auditory brainstem response measurements (ABR). Next, a series of interactive computer-based exercise sessions were performed with the therapist\u2019s assistance. Participants\u2019 actions were monitored with an eye-gaze tracking (EGT) device and with an electroencephalogram EEG monitoring headset. The data gathered were processed with the use of data clustering techniques.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Analysis showed that the data gathered and the computer-based methods developed for their processing are suitable for evaluating the participants\u2019 responses to stimuli. Parameters obtained from EEG signals and eye-tracker data were correlated with Glasgow Coma Scale (GCS) scores and enabled separation between GCS-related classes. The results show that in the EEG and eye-tracker signals, there are specific consciousness-related states discoverable. We observe them as outliers in diagrams on the decision space generated by the autoencoder. For this reason, the numerical variable that separates particular groups of people with the same GCS is the variance of the distance of points from the cluster center that the autoencoder generates. The higher the GCS score, the greater the variance in most cases. The results proved to be statistically significant in this context.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The results indicate that the method proposed may help to assess the consciousness state of participants in an objective manner.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12938-019-0746-y","type":"journal-article","created":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T17:03:01Z","timestamp":1578675781000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Multifactor consciousness level assessment of participants with acquired brain injuries employing human\u2013computer interfaces"],"prefix":"10.1186","volume":"19","author":[{"given":"Andrzej","family":"Czy\u017cewski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5132-3016","authenticated-orcid":false,"given":"Adam","family":"Kurowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Odya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Szczuko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,10]]},"reference":[{"issue":"10","key":"746_CR1","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1007\/s00701-015-2512-7","volume":"157","author":"W Peeters","year":"2015","unstructured":"Peeters W, van den Brande R, Polinder S, Brazinova A, Steyerberg EW, Lingsma HF, Maas AIR. 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The positive decision of this committee (No. KB 115\/2017) was issued on February 2nd, 2017. The ethics committee of the Collegium Medicum Ludwika Rydygiera being a part of a large medical university located in the city of Bydgoszcz, Poland, was the body authorized to review the research plan submitted by the \u201cEPIMIGREN\u201d medical care center located in the village of Osielsko, near Bydgoszcz. Written informed consent for participation was obtained from the carers and relatives of all involved participants.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"2"}}