{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T18:29:32Z","timestamp":1774549772779,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T00:00:00Z","timestamp":1709683200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T00:00:00Z","timestamp":1709683200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"The project of \u201cthe value of lung ultrasound in the differential diagnosis of neonatal respiratory distress syndrome and common lung diseases","award":["Y20211037"],"award-info":[{"award-number":["Y20211037"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BioMed Eng OnLine"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>To explore the predictive value of bedside lung ultrasound score in the severity of neonatal respiratory distress syndrome (NRDS) and mechanical ventilation and extubation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The clinical data of 65 neonates with NRDS and invasive mechanical ventilation diagnosed in the neonatal intensive care unit of our hospital from July 2021 to July 2022 were retrospectively analyzed. 65 neonates were included in the NRDS group, and 40 neonates with other common lung diseases were selected as the other lung disease groups. All neonates underwent lung ultrasound and X-ray examination. The correlation between lung ultrasound scores and arterial blood gas indexes was analyzed by Pearson. The efficacy of successful evacuation of mechanical ventilation was evaluated by lung ultrasound analysis by ROC curve analysis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The positive rates of lung consolidation and white lung in NRDS group were higher than the other lung disease groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The positive rates of bronchial inflation sign and double lung points were lower than these in the other lung disease groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The ultrasound scores of both lungs, left lung, right lung, bilateral lung and double basal lung in the NRDS group were significantly higher than those in the other lung disease groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). There was a significant positive correlation between lung ultrasound score and X-ray grade (<jats:italic>r<\/jats:italic>\u2009=\u20090.841, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The area under the curve (AUC) of lung ultrasound score for the differential diagnosis of NRDS and common lung diseases was 0.907. The AUC of lung ultrasound score in the differential diagnosis of mild and moderate, and moderate and severe NRDS were 0.914 and 0.933, respectively, which had high clinical value. The lung ultrasound score was positively correlated with the level of PaCO<jats:sub>2<\/jats:sub> (<jats:italic>r<\/jats:italic>\u2009=\u20090.254, <jats:italic>P<\/jats:italic>\u2009=\u20090.041), and negatively correlated with the levels of SpO<jats:sub>2<\/jats:sub> and PaO<jats:sub>2<\/jats:sub> (<jats:italic>r<\/jats:italic>\u2009=\u2009\u2212\u00a00.459, \u2212\u00a00.362, <jats:italic>P<\/jats:italic>\u2009=\u20090.001, 0.003). The AUC of successful mechanical ventilation withdrawal predicted by the pulmonary ultrasound score before extubation was 0.954 (95% CI 0.907\u20131.000). The predictive value of successful extubation was 10 points of the pulmonary ultrasound score, with a sensitivity of 93.33% and a specificity of 88.00%.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The bedside lung ultrasound score can intuitively reflect the respiratory status of neonates, which provides clinicians with an important basis for disease evaluation.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12938-024-01224-0","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T16:02:06Z","timestamp":1709740926000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Diagnostic value of bedside lung ultrasound and 12-zone score in the 65 cases of neonatal respiratory distress syndrome and its severity"],"prefix":"10.1186","volume":"23","author":[{"given":"Peipei","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuxiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiazi","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,6]]},"reference":[{"issue":"4","key":"1224_CR1","first-page":"385","volume":"116","author":"K Merja","year":"2020","unstructured":"Merja K, Anne-Sea V, Waldmann AD, et al. 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