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Ocular biometric measurements were acquired using the IOL Master 700, a swept-source optical coherence tomography (SS-OCT) device.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Age was negatively correlated with axial length (AL), anterior chamber depth (ACD), white-to-white (WTW), and pupil diameter (PD) (r<jats:sub>AL<\/jats:sub>\u2009=\u2009\u2212\u20090.13, r<jats:sub>ACD<\/jats:sub>\u2009=\u2009\u2212\u20090.26, r<jats:sub>WTW<\/jats:sub>\u2009=\u2009\u2212\u20090.18, all P\u2009&lt;\u20090.001; r<jats:sub>PD<\/jats:sub>\u2009=\u2009\u2212\u20090.09, P\u2009&lt;\u20090.01) but positively correlated with total steep keratometry (TKs) (r<jats:sub>TKs<\/jats:sub>\u2009=\u20090.13, P\u2009&lt;\u20090.001). AL was negatively correlated with total flat keratometry (TKf), TKs, and WTW (r<jats:sub>TKf<\/jats:sub>\u2009=\u2009\u2212\u20090.3, r<jats:sub>TKs<\/jats:sub>\u2009=\u2009\u2212\u20090.27, r<jats:sub>WTW<\/jats:sub>\u2009=\u2009\u2212\u20090.18, all P\u2009&lt;\u20090.001) but positively correlated with ACD and PD (r<jats:sub>ACD<\/jats:sub>\u2009=\u20090.43, r<jats:sub>PD<\/jats:sub>\u2009=\u20090.10, all P\u2009&lt;\u20090.001). Men had smaller TK and PD but larger WTW than women.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>These findings highlight significant sex-related differences in biometric parameters among patients with nuclear cataract, which are closely related to AL and age. Considering variation with these parameters helps personalize surgical plans and prevent complications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s12938-025-01386-5","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T18:35:43Z","timestamp":1746815743000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["SS-OCT-based ocular biometric characteristics of patients with nuclear cataract"],"prefix":"10.1186","volume":"24","author":[{"given":"Zhao","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liming","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijie","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aihua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"1386_CR1","unstructured":"The Cataract and Artificial Lens Group of the Ophthalmology Branch of the Chinese Medical Association. 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