{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T07:20:18Z","timestamp":1773818418369,"version":"3.50.1"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Grant-in-Aid for Evidence-Based Medicine Research from the National Hospital Organization, Japan","award":["2015-EBM-02"],"award-info":[{"award-number":["2015-EBM-02"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Environ Health"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12940-018-0438-2","type":"journal-article","created":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T13:11:34Z","timestamp":1544793094000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Epidemiological association between multiple chemical sensitivity and birth by caesarean section: a nationwide case-control study"],"prefix":"10.1186","volume":"17","author":[{"given":"Kentaro","family":"Watai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuma","family":"Fukutomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Kamide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Sekiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masami","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,12,14]]},"reference":[{"key":"438_CR1","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/S0091-6749(99)70522-1","volume":"103","author":"American Academy of Allergy Asthma and immunology (AAAAI) Board of Directors","year":"1999","unstructured":"American Academy of Allergy Asthma and immunology (AAAAI) Board of Directors. Idiopathic environmental intolerances. J Allergy Clin Immunol. 1999;103:36\u201340.","journal-title":"J Allergy Clin Immunol"},{"key":"438_CR2","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1097\/00043764-199911000-00003","volume":"41","author":"College of Occupational and Environmental Medicine. ACOEM position statement","year":"1999","unstructured":"College of Occupational and Environmental Medicine. ACOEM position statement. Multiple chemical sensitivities: idiopathic environmental intolerance. J Occup Environ Med. 1999;41:940\u20132.","journal-title":"J Occup Environ Med"},{"key":"438_CR3","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1080\/00039896.1996.9936026","volume":"51","author":"WJ Meggs","year":"1996","unstructured":"Meggs WJ, Dunn KA, Bloch RM, Goodman PE, Davidoff AL. Prevalence and nature of allergy and chemical sensitivity in a general population. Arch Environ Health. 1996;51:275\u201382.","journal-title":"Arch Environ Health"},{"key":"438_CR4","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1177\/074823379401000501","volume":"10","author":"CS Miller","year":"1994","unstructured":"Miller CS. White paper: chemical sensitivity: history and phenomenology. Toxicol Ind Health. 1994;10:253\u201376.","journal-title":"Toxicol Ind Health"},{"key":"438_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/oxfordjournals.aje.a009908","volume":"150","author":"R Kreutzer","year":"1999","unstructured":"Kreutzer R, Neutra RR, Lashuay N. Prevalence of people reporting sensitivities to chemicals in a population-based survey. Am J Epidemiol. 1999;150:1\u201312.","journal-title":"Am J Epidemiol"},{"key":"438_CR6","doi-asserted-by":"publisher","first-page":"746","DOI":"10.2105\/AJPH.94.5.746","volume":"94","author":"SM Caress","year":"2004","unstructured":"Caress SM, Steinemann AC. Prevalence of multiple chemical sensitivities: a population-based study in the southeastern United States. Am J Public Health. 2004;94:746\u20137.","journal-title":"Am J Public Health"},{"key":"438_CR7","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.ijheh.2005.03.006","volume":"208","author":"C Hausteiner","year":"2005","unstructured":"Hausteiner C, Bornschein S, Hansen J, Zilker T, Forstl H. Self-reported chemical sensitivity in Germany: a population-based survey. Int J Hygiene Environ Health. 2005;208:271\u20138.","journal-title":"Int J Hygiene Environ Health."},{"key":"438_CR8","first-page":"246","volume":"44","author":"I Uchiyama","year":"2003","unstructured":"Uchiyama I, Murayama R. Studies on potential chemical sensitivity in Japan using QEESI sheet [in Japanese]. J Jpn SocAtmos Environ. 2003;44:246\u20137.","journal-title":"J Jpn SocAtmos Environ"},{"key":"438_CR9","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1191\/0748233703th180oa","volume":"19","author":"S Hojo","year":"2003","unstructured":"Hojo S, Kumano H, Yoshino H, Kakuta K, Ishikawa S. Application of quick environment exposure sensitivity inventory (QEESI) for Japanese population: study of reliability and validity of the questionnaire. Toxicol Industr Health. 2003;19:41\u20139.","journal-title":"Toxicol Industr Health"},{"key":"438_CR10","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1177\/074823379901500312","volume":"15","author":"CS Miller","year":"1996","unstructured":"Miller CS, Prihoda TJ. A controlled comparison of symptoms and chemical intolerances reported by gulf war veterans, implant recipients and persons with multiple chemical sensitivity. Toxicol Industr Health. 1996;15:386\u201397.","journal-title":"Toxicol Industr Health."},{"key":"438_CR11","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1177\/074823379901500311","volume":"15","author":"CS Miller","year":"1999","unstructured":"Miller CS, Prihoda TJ. The environmental exposure and sensitivity inventory (EESI): a standardized approach for measuring chemical intolerances for research and clinical applications. Toxicol Ind Health. 1999;15:370\u201385.","journal-title":"Toxicol Ind Health"},{"key":"438_CR12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1476-069X-6-6","volume":"6","author":"E Schnakenberg","year":"2007","unstructured":"Schnakenberg E, Fabig KR, Stanulla M, Strobl N, Lustig M, Fabig N, et al. A cross-sectional study of self-reported chemical-related sensitivity is associated with gene variants of drug-metabolizing enzymes. Environ Health. 2007;6:6.","journal-title":"Environ Health"},{"key":"438_CR13","doi-asserted-by":"publisher","unstructured":"Skovbjerg S, Berg ND, Elberling J, Christensen KB. Evaluation of the quick environmental exposure and sensitivity inventory in a Danish population. J Environ Public Health. 2012:304314. https:\/\/doi.org\/10.1155\/2012\/304314.","DOI":"10.1155\/2012\/304314."},{"key":"438_CR14","doi-asserted-by":"publisher","first-page":"409","DOI":"10.4168\/aair.2014.6.5.409","volume":"6","author":"I Jeong","year":"2014","unstructured":"Jeong I, Kim I, Park HJ, Roh J, Park JW, Lee JH. Allergic diseases and multiple chemical sensitivity in korean adults. Allergy Asthma Immunol Res. 2014;6:409\u201314.","journal-title":"Allergy Asthma Immunol Res"},{"key":"438_CR15","first-page":"29","volume-title":"Fibromyalgia and other central pain syndromes. Lippincott Williams & Wilkims","author":"M Yunus","year":"2005","unstructured":"Yunus M. The concept of central sensitivity syndromes. In: Wallace DJ, Claw DJ, editors. Fibromyalgia and other central pain syndromes. Lippincott Williams & Wilkims; 2005. p. 29\u201344."},{"key":"438_CR16","first-page":"27","volume":"8","author":"M Yunus","year":"2000","unstructured":"Yunus M. Central sensitivity syndromes: a unified concept for fibromyalgia and other similar maladies. J Indian Rheum Assoc. 2000;8:27\u201333.","journal-title":"J Indian Rheum Assoc"},{"key":"438_CR17","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.semarthrit.2006.12.009","volume":"36","author":"MB Yunus","year":"2007","unstructured":"Yunus MB. Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes. Semin Arthritis Rheum. 2007;36:339\u201356.","journal-title":"Semin Arthritis Rheum"},{"key":"438_CR18","doi-asserted-by":"publisher","first-page":"S39","DOI":"10.1006\/rtph.1996.0075","volume":"24","author":"IR Bell","year":"1996","unstructured":"Bell IR, Schwartz GE, Baldwin CM, Hardin EE. Neural sensitization and physiological markers in multiple chemical sensitivity. Regul Toxicol Pharmacol. 1996;24:S39\u201347.","journal-title":"Regul Toxicol Pharmacol"},{"key":"438_CR19","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1111\/j.1365-2222.2008.02939.x","volume":"38","author":"P Bager","year":"2008","unstructured":"Bager P, Wohlfahrt J, Westergaard T. Caesarean delivery and risk of atopy and allergic disease: meta-analyses. Clin Exp Allergy. 2008;38:634\u201342.","journal-title":"Clin Exp Allergy"},{"key":"438_CR20","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1111\/j.1365-2222.2007.02780.x","volume":"38","author":"S Thavagnanam","year":"2008","unstructured":"Thavagnanam S, Fleming J, Bromley A, Shields MD. Cardwell CR. A meta-analysis of the association between caesarean section and childhood asthma. Clin Exp Allergy. 2008;38:629\u201333.","journal-title":"Clin Exp Allergy"},{"key":"438_CR21","doi-asserted-by":"publisher","first-page":"461","DOI":"10.3122\/jabfm.2015.04.140192","volume":"28","author":"LP Heilbrun","year":"2015","unstructured":"Heilbrun LP, Palmer RF, Jaen CR, Svoboda MD. Perkins J, Miller CS. Maternal chemical and drug intolerances: potential risk factors for autism and attention deficit hyperactivity disorder (ADHD). J Am Board Fam Med. 2015;28:461\u201370.","journal-title":"J Am Board Fam Med"},{"key":"438_CR22","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.ebiom.2014.11.004","volume":"1","author":"JJ Goedert","year":"2014","unstructured":"Goedert JJ, Hua X, Yu G, Shi J. Diversity and composition of the adult fecal microbiome associated with history of cesarean birth or appendectomy: analysis of the American gut project. EBioMedicine. 2014;1:167\u201372.","journal-title":"EBioMedicine"},{"key":"438_CR23","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1136\/gutjnl-2012-303249","volume":"63","author":"HE Jakobsson","year":"2014","unstructured":"Jakobsson HE, Abrahamsson TR, Jenmalm MC, Harris K, Quince C, Jernberg C, et al. Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section. Gut. 2014;63:559\u201366.","journal-title":"Gut"},{"key":"438_CR24","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3389\/fped.2017.00200","volume":"5","author":"F Yasmin","year":"2017","unstructured":"Yasmin F, Tun HM, Konya TB, Guttman DS, Chari RS, Field CJ, et al. Cesarean section, formula feeding, and infant antibiotic exposure: separate and combined impacts on gut microbial changes in later infancy. Front Pediatr. 2017;5:200.","journal-title":"Front Pediatr"},{"key":"438_CR25","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1038\/nrmicro2876","volume":"10","author":"SM Collins","year":"2012","unstructured":"Collins SM, Surette M, Bercik P. The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol. 2012;10:735\u201342.","journal-title":"Nat Rev Microbiol"},{"key":"438_CR26","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1038\/nrn3346","volume":"13","author":"JF Cryan","year":"2012","unstructured":"Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012;13:701\u201312.","journal-title":"Nat Rev Neurosci"},{"key":"438_CR27","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1097\/MCO.0000000000000221","volume":"18","author":"TG Dinan","year":"2015","unstructured":"Dinan TG, Cryan JF. The impact of gut microbiota on brain and behaviour: implications for psychiatry. Curr Opin Clin Nutr Metab Care. 2015;18:552\u20138.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"438_CR28","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.ijheh.2012.02.010","volume":"216","author":"MT Tran","year":"2013","unstructured":"Tran MT, Arendt-Nielsen L, Kupers R, Elberling J. Multiple chemical sensitivity: on the scent of central sensitization. Int J Hygiene Environ Health. 2013;216:202\u201310.","journal-title":"Int J Hygiene Environ Health."},{"key":"438_CR29","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1002\/ejp.1154","volume":"22","author":"M Curatolo","year":"2018","unstructured":"Curatolo M. Central sensitization: Nice to know? Eur J Pain. 2018;22:214\u20135.","journal-title":"Eur J Pain"},{"key":"438_CR30","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1016\/j.jaci.2013.11.027","volume":"133","author":"BJ Undem","year":"2014","unstructured":"Undem BJ, Taylor-Clark T. Mechanisms underlying the neuronal-based symptoms of allergy. J Allergy Clin Immunol. 2014;133:1521\u201334.","journal-title":"J Allergy Clin Immunol"},{"key":"438_CR31","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1007\/s00259-014-2969-2","volume":"42","author":"A Chiaravalloti","year":"2015","unstructured":"Chiaravalloti A, Pagani M, Micarelli A, Di Pietro B, Genovesi G, Alessandrini M, et al. Cortical activity during olfactory stimulation in multiple chemical sensitivity: a (18)F-FDG PET\/CT study. Eur J Nucl Med Mol Imaging. 2015;42:733\u201340.","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"438_CR32","doi-asserted-by":"publisher","first-page":"605","DOI":"10.3109\/00016488109138547","volume":"91","author":"B Drettner","year":"1981","unstructured":"Drettner B, Kumlien J. Experimental studies of the human nasal air-conditioning capacity. Acta Otolaryngol. 1981;91:605\u20139.","journal-title":"Acta Otolaryngol"},{"key":"438_CR33","first-page":"102","volume":"45","author":"RM Naclerio","year":"2007","unstructured":"Naclerio RM, Pinto J, Assanasen P, Baroody FM. Observations on the ability of the nose to warm and humidify inspired air. Rhinology. 2007;45:102\u201311.","journal-title":"Rhinology"},{"key":"438_CR34","first-page":"65","volume":"118","author":"R Shturman-Ellstein","year":"1978","unstructured":"Shturman-Ellstein R, Zeballos RJ, Buckley JM, Souhrada JF. The beneficial effect of nasal breathing on exercise-induced bronchoconstriction. Am Rev Respir Dis. 1978;118:65\u201373.","journal-title":"Am Rev Respir Dis"},{"key":"438_CR35","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1111\/j.1440-1843.2008.01300.x","volume":"13","author":"M Hallani","year":"2008","unstructured":"Hallani M, Wheatley JR, Amis TC. Enforced mouth breathing decreases lung function in mild asthmatics. Respirol. 2008;13:553\u20138.","journal-title":"Respirol"},{"key":"438_CR36","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jtemb.2017.03.005","volume":"42","author":"DA Geier","year":"2017","unstructured":"Geier DA, Kern JK, Geier MR. Increased risk for an atypical autism diagnosis following thimerosal-containing vaccine exposure in the United States: a prospective longitudinal case-control study in the vaccine safety datalink. J Trace Elem Med Biol. 2017;42:18\u201324.","journal-title":"J Trace Elem Med Biol"},{"key":"438_CR37","doi-asserted-by":"publisher","first-page":"2770","DOI":"10.3390\/ijerph8072770","volume":"8","author":"C Luca De","year":"2011","unstructured":"De Luca C, Raskovic D, Pacifico V, Thai JC, Korkina L. The search for reliable biomarkers of disease in multiple chemical sensitivity and other environmental intolerances. Int J Environ Res Public Health. 2011;8:2770\u201397.","journal-title":"Int J Environ Res Public Health"},{"key":"438_CR38","doi-asserted-by":"crossref","unstructured":"Fisk WJ, Mirer AG, Mendell MJ. Quantitative relationship of sick building syndrome symptoms with ventilation rates. Indoor Air 20019. 19:159\u201365.","DOI":"10.1111\/j.1600-0668.2008.00575.x"},{"key":"438_CR39","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s00420-008-0301-9","volume":"82","author":"D Norback","year":"2008","unstructured":"Norback D, Nordstrom K. Sick building syndrome in relation to air exchange rate, CO2, room temperature and relative air humidity in university computer classrooms: an experimental study. Int Arch Occup Environ Health. 2008;82:21\u201330.","journal-title":"Int Arch Occup Environ Health"},{"key":"438_CR40","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/s00420-009-0395-8","volume":"82","author":"M Takeda","year":"2009","unstructured":"Takeda M, Saijo Y, Yuasa M, Kanazawa A, Araki A, Kishi R. Relationship between sick building syndrome and indoor environmental factors in newly built Japanese dwellings. Int Arch Occup Environ Health. 2009;82:583\u201393.","journal-title":"Int Arch Occup Environ Health"},{"key":"438_CR41","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.ijheh.2007.03.004","volume":"211","author":"BL Wang","year":"2008","unstructured":"Wang BL, Takigawa T, Yamasaki Y, Sakano N, Wang DH, Ogino K. Symptom definitions for SBS (sick building syndrome) in residential dwellings. Int J Hygiene Environ Health. 2008;211:114\u201320.","journal-title":"Int J Hygiene Environ Health"},{"key":"438_CR42","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1002\/ajim.20095","volume":"46","author":"LL Strong","year":"2004","unstructured":"Strong LL, Thompson B, Coronado GD, Griffith WC, Vigoren EM, Islas I. Health symptoms and exposure to organophosphate pesticides in farmworkers. Am J Industr Med. 2004;46:599\u2013606.","journal-title":"Am J Industr Med"},{"key":"438_CR43","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.3390\/ijerph8051402","volume":"8","author":"CA Damalas","year":"2011","unstructured":"Damalas CA, Eleftherohorinos IG. Pesticide exposure, safety issues and risk assessment indicators. Int J Environ Res Public Health. 2011;8:1402\u201319.","journal-title":"Int J Environ Res Public Health"},{"key":"438_CR44","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.taap.2005.01.025","volume":"207","author":"C Colosio","year":"2005","unstructured":"Colosio C, Birindelli S, Corsini E, Galli CL, Maroni M. Low level exposure to chemicals and immune system. Toxicol Appl Pharmacol. 2005;207:320\u20138.","journal-title":"Toxicol Appl Pharmacol"},{"key":"438_CR45","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1080\/02772248.2010.484252","volume":"92","author":"M Fareed","year":"2010","unstructured":"Fareed M, Pathak MK, Bihari V, Mudiam MKR, Patel DK, Mathur N, et al. Hematological and biochemical alterations in sprayers occupationally exposed to mixture of pesticides at a mango plantation in Lucknow. India Toxicol Environ Chem. 2010;92:1919\u201328.","journal-title":"India Toxicol Environ Chem"},{"key":"438_CR46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0069755","volume":"8","author":"M Fareed","year":"2013","unstructured":"Fareed M, Pathak MK, Bihari V, Kamal R, Srivastava AK, Kesavachandran CN. Adverse respiratory health and hematological alterations among agricultural workers occupationally exposed to organophosphate pesticides: a cross-sectional study in North India. PLoS One. 2013;8:e69755.","journal-title":"PLoS One"},{"key":"438_CR47","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.neuro.2012.01.004","volume":"33","author":"L London","year":"2012","unstructured":"London L, Beseler C, Bouchard MF, Bellinger DC, Colosio C, Grandjean P, et al. Neurobehavioral and neurodevelopmental effects of pesticide exposures. Neurotoxicol. 2012;33:887\u201396.","journal-title":"Neurotoxicol"},{"key":"438_CR48","doi-asserted-by":"publisher","first-page":"227","DOI":"10.5271\/sjweh.3133","volume":"37","author":"S Naidoo","year":"2011","unstructured":"Naidoo S, London L, Burdorf A, Naidoo R, Kromhout H. Spontaneous miscarriages and infant deaths among female farmers in rural South Africa. Scand J Work Env Health. 2011;37:227\u201336.","journal-title":"Scand J Work Env Health"},{"key":"438_CR49","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1179\/oeh.2002.8.1.14","volume":"8","author":"HG Penagos","year":"2002","unstructured":"Penagos HG. Contact dermatitis caused by pesticides among banana plantation workers in Panama. Int J Occup Environ Health. 2002;8:14\u20138.","journal-title":"Int J Occup Environ Health"},{"key":"438_CR50","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.jpsychores.2014.09.014","volume":"77","author":"L Andersson","year":"2014","unstructured":"Andersson L, Claeson AS, Nyberg L, Stenberg B, Nordin S. Brain responses to olfactory and trigeminal exposure in idiopathic environmental illness (IEI) attributed to smells\u2014an fMRI study. J Psychosom Res. 2014;77:401\u20138.","journal-title":"J Psychosom Res"},{"key":"438_CR51","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.taap.2010.04.017","volume":"248","author":"C Luca De","year":"2010","unstructured":"De Luca C, Scordo MG, Cesareo E, Pastore S, Mariani S, Maiani G, et al. Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes. Toxicol Appl Pharmacol. 2010;248:285\u201392.","journal-title":"Toxicol Appl Pharmacol"},{"key":"438_CR52","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1093\/ije\/dyh251","volume":"33","author":"G McKeown-Eyssen","year":"2004","unstructured":"McKeown-Eyssen G, Baines C, Cole DE, Riley N, Tyndale RF, Marshall L, et al. Case-control study of genotypes in multiple chemical sensitivity: CYP2D6, NAT1, NAT2, PON1, PON2 and MTHFR. Int J Epidemiol. 2004;33:971\u20138.","journal-title":"Int J Epidemiol"},{"key":"438_CR53","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.jns.2009.09.003","volume":"287","author":"R Orriols","year":"2009","unstructured":"Orriols R, Costa R, Cuberas G, Jacas C, Castell J, Sunyer J. Brain dysfunction in multiple chemical sensitivity. J Neurol Sci. 2009;287:72\u20138.","journal-title":"J Neurol Sci"},{"key":"438_CR54","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1002\/bem.21987","volume":"37","author":"S Hojo","year":"2016","unstructured":"Hojo S, Tokiya M, Mizuki M, Miyata M, Kanatani KT, Takagi A, et al. Development and evaluation of an electromagnetic hypersensitivity questionnaire for Japanese people. Bioelectromagnetics. 2016;37:353\u201372.","journal-title":"Bioelectromagnetics"}],"container-title":["Environmental Health"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12940-018-0438-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12940-018-0438-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12940-018-0438-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T09:32:46Z","timestamp":1662629566000},"score":1,"resource":{"primary":{"URL":"https:\/\/ehjournal.biomedcentral.com\/articles\/10.1186\/s12940-018-0438-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["438"],"URL":"https:\/\/doi.org\/10.1186\/s12940-018-0438-2","relation":{},"ISSN":["1476-069X"],"issn-type":[{"value":"1476-069X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"21 February 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 December 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 December 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study participants provided informed consent when they registered for the web-based survey. The ethics committee of the Sagamihara National Hospital approved the study protocol (No. 150912, approved on September 15, 2015), which was in accordance with the Declaration of Helsinki.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable. There are no individual level data in our study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"89"}}