{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T12:17:12Z","timestamp":1783772232799,"version":"3.55.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T00:00:00Z","timestamp":1488844800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T00:00:00Z","timestamp":1488844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["CA 157481"],"award-info":[{"award-number":["CA 157481"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL120585"],"award-info":[{"award-number":["HL120585"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mol Cancer"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12943-017-0617-8","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T13:35:00Z","timestamp":1488893700000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["BMI1, a new target of CK2\u03b1"],"prefix":"10.1186","volume":"16","author":[{"given":"Soumyajit","family":"Banerjee Mustafi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabir Kumar","family":"Chakraborty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailendra Kumar Dhar","family":"Dwivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine M.","family":"Moxley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyabrata","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Resham","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,3,7]]},"reference":[{"issue":"2","key":"617_CR1","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1172\/JCI200420800","volume":"113","author":"IK Park","year":"2004","unstructured":"Park IK, Morrison SJ, Clarke MF. Bmi1, stem cells, and senescence regulation. J Clin Invest. 2004;113(2):175\u20139.","journal-title":"J Clin Invest"},{"issue":"3","key":"617_CR2","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1002\/stem.1035","volume":"30","author":"HR Siddique","year":"2012","unstructured":"Siddique HR, Saleem M. Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences. Stem Cells. 2012;30(3):372\u20138.","journal-title":"Stem Cells"},{"issue":"5","key":"617_CR3","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1172\/JCI57477","volume":"122","author":"K Nacerddine","year":"2012","unstructured":"Nacerddine K, Beaudry JB, Ginjala V, Westerman B, Mattiroli F, Song JY, van der Poel H, Ponz OB, Pritchard C, Cornelissen-Steijger P, et al. Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer. J Clin Invest. 2012;122(5):1920\u201332.","journal-title":"J Clin Invest"},{"issue":"10","key":"617_CR4","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.1128\/MCB.00981-10","volume":"31","author":"V Ginjala","year":"2011","unstructured":"Ginjala V, Nacerddine K, Kulkarni A, Oza J, Hill SJ, Yao M, Citterio E, van Lohuizen M, Ganesan S. BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol Cell Biol. 2011;31(10):1972\u201382.","journal-title":"Mol Cell Biol"},{"issue":"12","key":"617_CR5","doi-asserted-by":"publisher","first-page":"5497","DOI":"10.1093\/nar\/gks222","volume":"40","author":"IH Ismail","year":"2012","unstructured":"Ismail IH, Gagne JP, Caron MC, McDonald D, Xu Z, Masson JY, Poirier GG, Hendzel MJ. CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. Nucleic Acids Res. 2012;40(12):5497\u2013510.","journal-title":"Nucleic Acids Res"},{"issue":"7245","key":"617_CR6","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1038\/nature08040","volume":"459","author":"J Liu","year":"2009","unstructured":"Liu J, Cao L, Chen J, Song S, Lee IH, Quijano C, Liu H, Keyvanfar K, Chen H, Cao LY, et al. Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature. 2009;459(7245):387\u201392.","journal-title":"Nature"},{"key":"617_CR7","doi-asserted-by":"crossref","unstructured":"Banerjee Mustafi S, Aznar N, Dwivedi SK, Chakraborty PK, Basak R, Mukherjee P, Ghosh P, Bhattacharya R. Mitochondrial BMI1 maintains bioenergetic homeostasis in cells. FASEB J. 2016;30(12):4042-55.","DOI":"10.1096\/fj.201600321R"},{"issue":"1","key":"617_CR8","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1038\/nm.3418","volume":"20","author":"A Kreso","year":"2014","unstructured":"Kreso A, van Galen P, Pedley NM, Lima-Fernandes E, Frelin C, Davis T, Cao L, Baiazitov R, Du W, Sydorenko N, et al. Self-renewal as a therapeutic target in human colorectal cancer. Nat Med. 2014;20(1):29\u201336.","journal-title":"Nat Med"},{"issue":"1","key":"617_CR9","doi-asserted-by":"crossref","first-page":"745","DOI":"10.18632\/oncotarget.6378","volume":"7","author":"C Mayr","year":"2016","unstructured":"Mayr C, Wagner A, Loeffelberger M, Bruckner D, Jakab M, Berr F, Di Fazio P, Ocker M, Neureiter D, Pichler M, et al. The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells. Oncotarget. 2016;7(1):745\u201358.","journal-title":"Oncotarget"},{"issue":"4","key":"617_CR10","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1080\/15548627.2016.1147670","volume":"12","author":"A Dey","year":"2016","unstructured":"Dey A, Mustafi SB, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12(4):659\u201370.","journal-title":"Autophagy"},{"issue":"3","key":"617_CR11","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.gendis.2015.04.001","volume":"2","author":"R Bhattacharya","year":"2015","unstructured":"Bhattacharya R, Mustafi SB, Street M, Dey A, Dwivedi SK. Bmi-1: At the crossroads of physiological and pathological biology. Genes Dis. 2015;2(3):225\u201339.","journal-title":"Genes Dis"},{"issue":"247","key":"617_CR12","doi-asserted-by":"publisher","first-page":"ra77","DOI":"10.1126\/scisignal.2003199","volume":"5","author":"Y Liu","year":"2012","unstructured":"Liu Y, Liu F, Yu H, Zhao X, Sashida G, Deblasio A, Harr M, She QB, Chen Z, Lin HK, et al. Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus. Sci Signal. 2012;5(247):ra77.","journal-title":"Sci Signal"},{"issue":"7","key":"617_CR13","doi-asserted-by":"publisher","first-page":"5178","DOI":"10.1074\/jbc.M407155200","volume":"280","author":"JW Voncken","year":"2005","unstructured":"Voncken JW, Niessen H, Neufeld B, Rennefahrt U, Dahlmans V, Kubben N, Holzer B, Ludwig S, Rapp UR. MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1. J Biol Chem. 2005;280(7):5178\u201387.","journal-title":"J Biol Chem"},{"issue":"5","key":"617_CR14","doi-asserted-by":"publisher","first-page":"1838","DOI":"10.1002\/jcp.22912","volume":"227","author":"G Sustackova","year":"2012","unstructured":"Sustackova G, Kozubek S, Stixova L, Legartova S, Matula P, Orlova D, Bartova E. Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin. J Cell Physiol. 2012;227(5):1838\u201350.","journal-title":"J Cell Physiol"},{"key":"617_CR15","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1186\/1476-4598-9-158","volume":"9","author":"AK Yadav","year":"2010","unstructured":"Yadav AK, Sahasrabuddhe AA, Dimri M, Bommi PV, Sainger R, Dimri GP. Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain. Mol Cancer. 2010;9:158.","journal-title":"Mol Cancer"},{"issue":"Pt 1","key":"617_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1042\/bj20021469","volume":"369","author":"DW Litchfield","year":"2003","unstructured":"Litchfield DW. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J. 2003;369(Pt 1):1\u201315.","journal-title":"Biochem J"},{"issue":"3","key":"617_CR17","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1096\/fj.02-0473rev","volume":"17","author":"F Meggio","year":"2003","unstructured":"Meggio F, Pinna LA. One-thousand-and-one substrates of protein kinase CK2? FASEB J. 2003;17(3):349\u201368.","journal-title":"FASEB J"},{"issue":"19","key":"617_CR18","doi-asserted-by":"publisher","first-page":"5320","DOI":"10.1093\/emboj\/20.19.5320","volume":"20","author":"K Niefind","year":"2001","unstructured":"Niefind K, Guerra B, Ermakowa I, Issinger OG. Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme. EMBO J. 2001;20(19):5320\u201331.","journal-title":"EMBO J"},{"issue":"12","key":"617_CR19","doi-asserted-by":"publisher","first-page":"e115609","DOI":"10.1371\/journal.pone.0115609","volume":"9","author":"CE Ortega","year":"2014","unstructured":"Ortega CE, Seidner Y, Dominguez I. Mining CK2 in cancer. PLoS One. 2014;9(12):e115609.","journal-title":"PLoS One"},{"issue":"23","key":"617_CR20","doi-asserted-by":"publisher","first-page":"9090","DOI":"10.1158\/0008-5472.CAN-09-2552","volume":"69","author":"R Bhattacharya","year":"2009","unstructured":"Bhattacharya R, Nicoloso M, Arvizo R, Wang E, Cortez A, Rossi S, Calin GA, Mukherjee P. MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer. Cancer Res. 2009;69(23):9090\u20135.","journal-title":"Cancer Res"},{"issue":"2","key":"617_CR21","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.anndiagpath.2013.11.004","volume":"18","author":"A Abd El hafez","year":"2014","unstructured":"Abd El hafez A, El-Hadaad HA. Immunohistochemical expression and prognostic relevance of Bmi-1, a stem cell factor, in epithelial ovarian cancer. Ann Diagn Pathol. 2014;18(2):58\u201362.","journal-title":"Ann Diagn Pathol"},{"key":"617_CR22","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/B978-0-12-381298-8.00023-X","volume":"484","author":"JP Turowec","year":"2010","unstructured":"Turowec JP, Duncan JS, French AC, Gyenis L, St Denis NA, Vilk G, Litchfield DW. Protein kinase CK2 is a constitutively active enzyme that promotes cell survival: strategies to identify CK2 substrates and manipulate its activity in mammalian cells. Methods Enzymol. 2010;484:471\u201393.","journal-title":"Methods Enzymol"},{"issue":"1","key":"617_CR23","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1477-5956-10-56","volume":"10","author":"H Guo","year":"2012","unstructured":"Guo H, Liu W, Ju Z, Tamboli P, Jonasch E, Mills GB, Lu Y, Hennessy BT, Tsavachidou D. An efficient procedure for protein extraction from formalin-fixed, paraffin-embedded tissues for reverse phase protein arrays. Proteome Sci. 2012;10(1):56.","journal-title":"Proteome Sci"},{"issue":"18","key":"617_CR24","doi-asserted-by":"publisher","first-page":"2891","DOI":"10.1089\/ars.2013.5340","volume":"20","author":"S Banerjee Mustafi","year":"2014","unstructured":"Banerjee Mustafi S, Grose JH, Zhang H, Pratt GW, Sadoshima J, Christians ES, Benjamin IJ. Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin system. Antioxid Redox Signal. 2014;20(18):2891\u2013906.","journal-title":"Antioxid Redox Signal"},{"issue":"10","key":"617_CR25","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1038\/nprot.2009.154","volume":"4","author":"E Kinoshita","year":"2009","unstructured":"Kinoshita E, Kinoshita-Kikuta E, Koike T. Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE. Nat Protoc. 2009;4(10):1513\u201321.","journal-title":"Nat Protoc"},{"key":"617_CR26","first-page":"336","volume":"6","author":"S Bekesova","year":"2015","unstructured":"Bekesova S, Komis G, Krenek P, Vyplelova P, Ovecka M, Luptovciak I, Illes P, Kucharova A, Samaj J. Monitoring protein phosphorylation by acrylamide pendant Phos-Tag in various plants. Front Plant Sci. 2015;6:336.","journal-title":"Front Plant Sci"},{"issue":"2","key":"617_CR27","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1074\/mcp.T600044-MCP200","volume":"6","author":"E Kinoshita-Kikuta","year":"2007","unstructured":"Kinoshita-Kikuta E, Aoki Y, Kinoshita E, Koike T. Label-free kinase profiling using phosphate affinity polyacrylamide gel electrophoresis. Mol Cell Proteomics. 2007;6(2):356\u201366.","journal-title":"Mol Cell Proteomics"},{"issue":"5","key":"617_CR28","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1006\/jmbi.1999.3310","volume":"294","author":"N Blom","year":"1999","unstructured":"Blom N, Gammeltoft S, Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol. 1999;294(5):1351\u201362.","journal-title":"J Mol Biol"},{"issue":"Web Server issu","key":"617_CR29","doi-asserted-by":"publisher","first-page":"W588","DOI":"10.1093\/nar\/gkm322","volume":"35","author":"YH Wong","year":"2007","unstructured":"Wong YH, Lee TY, Liang HK, Huang CM, Wang TY, Yang YH, Chu CH, Huang HD, Ko MT, Hwang JK. KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns. Nucleic Acids Res. 2007;35(Web Server issue):W588\u201394.","journal-title":"Nucleic Acids Res"},{"issue":"Pt 2","key":"617_CR30","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1042\/bj3570563","volume":"357","author":"A Donella-Deana","year":"2001","unstructured":"Donella-Deana A, Cesaro L, Sarno S, Brunati AM, Ruzzene M, Pinna LA. Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha\u2019 subunits: implication of Tyr182. Biochem J. 2001;357(Pt 2):563\u20137.","journal-title":"Biochem J"},{"issue":"Pt 1","key":"617_CR31","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1042\/bj3640041","volume":"364","author":"M Ruzzene","year":"2002","unstructured":"Ruzzene M, Penzo D, Pinna LA. Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. Biochem J. 2002;364(Pt 1):41\u20137.","journal-title":"Biochem J"},{"key":"617_CR32","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1756-8722-5-8","volume":"5","author":"J Li","year":"2012","unstructured":"Li J, Fadare O, Xiang L, Kong B, Zheng W. Ovarian serous carcinoma: recent concepts on its origin and carcinogenesis. J Hematol Oncol. 2012;5:8.","journal-title":"J Hematol Oncol"},{"issue":"8","key":"617_CR33","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.4161\/cc.10.8.15372","volume":"10","author":"AA Sahasrabuddhe","year":"2011","unstructured":"Sahasrabuddhe AA, Dimri M, Bommi PV, Dimri GP. betaTrCP regulates BMI1 protein turnover via ubiquitination and degradation. Cell Cycle. 2011;10(8):1322\u201330.","journal-title":"Cell Cycle"},{"issue":"3","key":"617_CR34","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.ccr.2014.07.009","volume":"26","author":"X Hu","year":"2014","unstructured":"Hu X, Feng Y, Zhang D, Zhao SD, Hu Z, Greshock J, Zhang Y, Yang L, Zhong X, Wang LP, et al. A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. Cancer Cell. 2014;26(3):344\u201357.","journal-title":"Cancer Cell"},{"issue":"5298","key":"617_CR35","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1126\/science.275.5298.400","volume":"275","author":"AM Musti","year":"1997","unstructured":"Musti AM, Treier M, Bohmann D. Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases. Science. 1997;275(5298):400\u20132.","journal-title":"Science"},{"issue":"5449","key":"617_CR36","doi-asserted-by":"publisher","first-page":"2514","DOI":"10.1126\/science.286.5449.2514","volume":"286","author":"JM Brondello","year":"1999","unstructured":"Brondello JM, Pouyssegur J, McKenzie FR. Reduced MAP kinase phosphatase-1 degradation after p42\/p44MAPK-dependent phosphorylation. Science. 1999;286(5449):2514\u20137.","journal-title":"Science"},{"issue":"19","key":"617_CR37","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.1101\/gad.836800","volume":"14","author":"R Sears","year":"2000","unstructured":"Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev. 2000;14(19):2501\u201314.","journal-title":"Genes Dev"},{"issue":"5","key":"617_CR38","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1016\/j.molcel.2007.11.019","volume":"28","author":"T Hunter","year":"2007","unstructured":"Hunter T. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol Cell. 2007;28(5):730\u20138.","journal-title":"Mol Cell"},{"issue":"14","key":"617_CR39","first-page":"1001","volume":"1","author":"UM Moll","year":"2003","unstructured":"Moll UM, Petrenko O. The MDM2-p53 interaction. Mol Cancer Res. 2003;1(14):1001\u20138.","journal-title":"Mol Cancer Res"},{"issue":"22","key":"617_CR40","doi-asserted-by":"publisher","first-page":"6061","DOI":"10.1093\/emboj\/cdf626","volume":"21","author":"J Sheng","year":"2002","unstructured":"Sheng J, Kumagai A, Dunphy WG, Varshavsky A. Dissection of c-MOS degron. EMBO J. 2002;21(22):6061\u201371.","journal-title":"EMBO J"},{"issue":"4","key":"617_CR41","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1158\/1535-7163.MCT-11-0613","volume":"11","author":"A Siddiqui-Jain","year":"2012","unstructured":"Siddiqui-Jain A, Bliesath J, Macalino D, Omori M, Huser N, Streiner N, Ho CB, Anderes K, Proffitt C, O\u2019Brien SE, et al. CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy. Mol Cancer Ther. 2012;11(4):994\u20131005.","journal-title":"Mol Cancer Ther"}],"container-title":["Molecular Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12943-017-0617-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12943-017-0617-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12943-017-0617-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T07:31:22Z","timestamp":1589527882000},"score":1,"resource":{"primary":{"URL":"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-017-0617-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,7]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["617"],"URL":"https:\/\/doi.org\/10.1186\/s12943-017-0617-8","relation":{},"ISSN":["1476-4598"],"issn-type":[{"value":"1476-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,7]]},"assertion":[{"value":"2 December 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"56"}}