{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:08:36Z","timestamp":1791137316065,"version":"4.1.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lipids Health Dis"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s12944-015-0161-8","type":"journal-article","created":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T08:03:18Z","timestamp":1448956998000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Long-term dietary supplementation with saury oil attenuates metabolic abnormalities in mice fed a high-fat diet: combined beneficial effect of omega-3 fatty acids and long-chain monounsaturated fatty acids"],"prefix":"10.1186","volume":"14","author":[{"given":"Zhi-Hong","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seika","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuko","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Miyahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiro","family":"Takeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Sakaue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Nakaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,1]]},"reference":[{"key":"161_CR1","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.mcna.2011.06.001","volume":"95","author":"EJ Gallagher","year":"2011","unstructured":"Gallagher EJ, Leroith D, Karnieli E. The metabolic syndrome--from insulin resistance to obesity and diabetes. Med Clin North Am. 2011;95:855\u201373.","journal-title":"Med Clin North Am"},{"key":"161_CR2","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/1741-7015-10-138","volume":"10","author":"K Yamaoka","year":"2012","unstructured":"Yamaoka K, Tango T. Effects of lifestyle modification on metabolic syndrome: a systematic review and meta-analysis. BMC Med. 2012;10:138.","journal-title":"BMC Med"},{"key":"161_CR3","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.plipres.2015.07.002","volume":"59","author":"H Poudyal","year":"2015","unstructured":"Poudyal H, Brown L. Should the pharmacological actions of dietary fatty acids in cardiometabolic disorders be classified based on biological or chemical function? Prog Lipid Res. 2015;59:172\u2013200.","journal-title":"Prog Lipid Res"},{"issue":"Suppl 2","key":"161_CR4","doi-asserted-by":"crossref","first-page":"B1","DOI":"10.1016\/j.numecd.2011.05.001","volume":"21","author":"I Abete","year":"2011","unstructured":"Abete I, Goyenechea E, Zulet MA, Mart\u00ednez JA. Obesity and metabolic syndrome: potential benefit from specific nutritional components. Nutr Metab Cardiovasc Dis. 2011;21(Suppl 2):B1\u201315.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"161_CR5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3354\/meps003011","volume":"3","author":"T Ota","year":"1980","unstructured":"Ota T, Takagi T, Kosaka S. Changes in lipids of young and adult saury cololabis saira (Pisces). Mar Ecol Prog Ser. 1980;3:11\u20137.","journal-title":"Mar Ecol Prog Ser"},{"key":"161_CR6","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1300\/J030v14n01_07","volume":"14","author":"ACM Oliveiraa","year":"2005","unstructured":"Oliveiraa ACM, Bechtelb PJ. Lipid composition of Alaska pink salmon (Oncorhynchus gorbuscha) and Alaska walleye pollock (Theragra chalcogramma) byproducts. J Aquat Food Prod Tech. 2005;14:73\u201391.","journal-title":"J Aquat Food Prod Tech"},{"key":"161_CR7","doi-asserted-by":"crossref","first-page":"7482","DOI":"10.1021\/jf201496h","volume":"59","author":"ZH Yang","year":"2011","unstructured":"Yang ZH, Miyahara H, Mori T, Doisaki N, Hatanaka A. Beneficial effects of dietary fish-oil-derived monounsaturated fatty acids on metabolic syndrome risk factors and insulin resistance in mice. J Agric Food Chem. 2011;59:7482\u20139.","journal-title":"J Agric Food Chem"},{"key":"161_CR8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1743-7075-10-16","volume":"10","author":"ZH Yang","year":"2013","unstructured":"Yang ZH, Miyahara H, Iwasaki Y, Takeo J, Katayama M. Dietary supplementation with long-chain monounsaturated fatty acids attenuates obesity-related metabolic dysfunction and increases expression of PPAR gamma in adipose tissue in type 2 diabetic KK-Ay mice. Nutr Metab (Lond). 2013;10:16.","journal-title":"Nutr Metab (Lond)"},{"key":"161_CR9","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s11745-011-3553-1","volume":"46","author":"ZH Yang","year":"2011","unstructured":"Yang ZH, Miyahara H, Takemura S, Hatanaka A. Dietary saury oil reduces hyperglycemia and hyperlipidemia in diabetic KKAy mice and in diet-induced obese C57BL\/6\u00a0J mice by altering gene expression. Lipids. 2011;46:425\u201334.","journal-title":"Lipids"},{"key":"161_CR10","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s13105-013-0265-4","volume":"69","author":"S1 Lorente-Cebri\u00e1n","year":"2013","unstructured":"Lorente-Cebri\u00e1n S1, Costa AG, Navas-Carretero S, Zabala M, Mart\u00ednez JA, Moreno-Aliaga MJ. Role of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: a review of the evidence. J Physiol Biochem. 2013;69:633\u201351.","journal-title":"J Physiol Biochem"},{"key":"161_CR11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.3164\/jcbn.09-83","volume":"46","author":"JC Fraulob","year":"2010","unstructured":"Fraulob JC, Ogg-Diamantino R, Fernandes-Santos C, Aguila MB, Mandarim-de-Lacerda CA. A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL\/6 mice fed a high fat diet. J Clin Biochem Nutr. 2010;46:212\u201323.","journal-title":"J Clin Biochem Nutr"},{"key":"161_CR12","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0022-2275(20)38861-1","volume":"27","author":"G Lepage","year":"1986","unstructured":"Lepage G, Roy CC. Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res. 1986;27:114\u201320.","journal-title":"J Lipid Res"},{"key":"161_CR13","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","volume":"226","author":"J Folch","year":"1957","unstructured":"Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957;226:497\u2013509.","journal-title":"J Biol Chem"},{"key":"161_CR14","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1074\/jbc.M608144200","volume":"282","author":"T Sakai","year":"2007","unstructured":"Sakai T, Sakaue H, Nakamura T, Okada M, Matsuki Y, Watanabe E, et al. Skp2 controls adipocyte proliferation during the development of obesity. J Biol Chem. 2007;282:2038\u201346.","journal-title":"J Biol Chem"},{"key":"161_CR15","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.molmet.2015.04.003","volume":"4","author":"DJ Pedersen","year":"2015","unstructured":"Pedersen DJ, Guilherme A, Danai LV, Heyda L, Matevossian A, Cohen J, et al. A major role of insulin in promoting obesity-associated adipose tissue inflammation. Mol Metab. 2015;4:507\u201318.","journal-title":"Mol Metab"},{"key":"161_CR16","doi-asserted-by":"crossref","first-page":"852","DOI":"10.2174\/138161211795428849","volume":"17","author":"JR Schaefer","year":"2011","unstructured":"Schaefer JR. Lipid management for the prevention of cardiovascular disease. Curr Pharm Des. 2011;17:852\u201360.","journal-title":"Curr Pharm Des"},{"key":"161_CR17","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","volume":"85","author":"Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults","year":"2001","unstructured":"Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;85:2486\u201397.","journal-title":"JAMA"},{"key":"161_CR18","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/eci.12129","volume":"43","author":"BM Sondermeijer","year":"2013","unstructured":"Sondermeijer BM, Rana JS, Arsenault BJ, Shah PK, Kastelein JJ, Wareham NJ, et al. Non-HDL cholesterol vs. apo B for risk of coronary heart disease in healthy individuals: the EPIC-Norfolk prospective population study. Eur J Clin Invest. 2013;43:1009\u201315.","journal-title":"Eur J Clin Invest"},{"key":"161_CR19","doi-asserted-by":"crossref","first-page":"232","DOI":"10.2174\/187153011796429817","volume":"11","author":"MY Abeywardena","year":"2011","unstructured":"Abeywardena MY, Patten GS. Role of \u03c93 long-chain polyunsaturated fatty acids in reducing cardio-metabolic risk factors. Endocr Metab ImmuneDisord Drug Targets. 2011;11:232\u201346.","journal-title":"Endocr Metab ImmuneDisord Drug Targets"},{"key":"161_CR20","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1093\/jn\/137.12.2629","volume":"137","author":"T1 Mori","year":"2007","unstructured":"Mori T1, Kondo H, Hase T, Tokimitsu I, Murase T. Dietary fish oil upregulates intestinal lipid metabolism and reduces body weight gain in C57BL\/6J mice. J Nutr. 2007;137:2629\u201334.","journal-title":"J Nutr"},{"key":"161_CR21","first-page":"58","volume":"10","author":"U Schwab","year":"2014","unstructured":"Schwab U, Lauritzen L, Tholstrup T, Haldorssoni T, Riserus U, Uusitupa M, et al. Effect of the amount and type of dietary fat on cardiometabolic risk factors and risk of developing type 2 diabetes, cardiovascular diseases, and cancer: a systematic review. Food Nutr Res. 2014;10:58.","journal-title":"Food Nutr Res"},{"key":"161_CR22","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3945\/ajcn.2009.27661","volume":"91","author":"JE Hunter","year":"2010","unstructured":"Hunter JE, Zhang J, Kris-Etherton PM. Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review. Am J Clin Nutr. 2010;91:46\u201363.","journal-title":"Am J Clin Nutr"},{"key":"161_CR23","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s11745-013-3840-0","volume":"48","author":"A Dillard","year":"2013","unstructured":"Dillard A, Matthan NR, Spartano NL, Butkowski AE, Lichtenstein AH. Background diet and fat type alters plasma lipoprotein response but not aortic cholesterol accumulation in F1B Golden Syrian hamsters. Lipids. 2013;48:1177\u201384.","journal-title":"Lipids"},{"key":"161_CR24","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s11745-002-0959-2","volume":"37","author":"V Morvan le","year":"2002","unstructured":"le Morvan V, Dumon MF, Palos-Pinto A, B\u00e9rard AM. n-3 FA increase liver uptake of HDL-cholesterol in mice. Lipids. 2002;37:767\u201372.","journal-title":"Lipids"},{"key":"161_CR25","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1093\/ajcn\/52.4.632","volume":"52","author":"MT Childs","year":"1990","unstructured":"Childs MT, King IB, Knopp RH. Divergent lipoprotein responses to fish oils with various ratios of eicosapentaenoic acid and docosahexaenoic acid. Am J Clin Nutr. 1990;52:632\u20139.","journal-title":"Am J Clin Nutr"},{"key":"161_CR26","doi-asserted-by":"crossref","first-page":"436","DOI":"10.3945\/ajcn.113.070557","volume":"99","author":"CL Kien","year":"2014","unstructured":"Kien CL, Bunn JY, Stevens R, Bain J, Ikayeva O, Crain K, et al. Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans. Am J Clin Nutr. 2014;99:436\u201345.","journal-title":"Am J Clin Nutr"},{"key":"161_CR27","first-page":"1059","volume":"4","author":"SM1 Namayandeh","year":"2013","unstructured":"Namayandeh SM1, Kaseb F, Lesan S. Olive and sesame oil effect on lipid profile in hypercholesterolemic patients, which better? Int J Prev Med. 2013;4:1059\u201362.","journal-title":"Int J Prev Med"},{"key":"161_CR28","doi-asserted-by":"crossref","first-page":"15430","DOI":"10.1073\/pnas.0904944106","volume":"106","author":"E Fabbrini","year":"2009","unstructured":"Fabbrini E, Magkos F, Mohammed BS, Pietka T, Abumrad NA, Patterson BW, et al. Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A. 2009;106:15430\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"161_CR29","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.2337\/db09-1554","volume":"9","author":"A Sato","year":"2010","unstructured":"Sato A, Kawano H, Notsu T, Ohta M, Nakakuki M, Mizuguchi K, et al. Antiobesity effect of eicosapentaenoic acid in high-fat\/high-sucrose diet-induced obesity: importance of hepatic lipogenesis. Diabetes. 2010;9:2495\u2013504.","journal-title":"Diabetes"},{"key":"161_CR30","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.bbalip.2009.08.008","volume":"1791","author":"G Howell 3rd","year":"2009","unstructured":"Howell 3rd G, Deng X, Yellaturu C, Park EA, Wilcox HG, Raghow R, et al. N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha. Biochim Biophys Acta. 2009;1791:1190\u20136.","journal-title":"Biochim Biophys Acta"},{"key":"161_CR31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.plipres.2014.11.003","volume":"57","author":"P Dobrzyn","year":"2015","unstructured":"Dobrzyn P, Bednarski T, Dobrzyn A. Metabolic reprogramming of the heart through stearoyl-CoA desaturase. Prog Lipid Res. 2015;57:1\u201312.","journal-title":"Prog Lipid Res"},{"key":"161_CR32","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1017\/S0007114512005934","volume":"110","author":"B Vessby","year":"2013","unstructured":"Vessby B, Gustafsson IB, Tengblad S, Berglund L. Indices of fatty acid desaturase activity in healthy human subjects: effects of different types of dietary fat. Br J Nutr. 2013;110:871\u20139.","journal-title":"Br J Nutr"},{"key":"161_CR33","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/oby.20011","volume":"21","author":"KJ Vinknes","year":"2013","unstructured":"Vinknes KJ, Elshorbagy AK, Nurk E, Drevon CA, Gjesdal CG, Tell GS, et al. Plasma stearoyl-CoA desaturase indices: association with lifestyle, diet, and body composition. Obesity. 2013;21:294\u2013302.","journal-title":"Obesity"},{"key":"161_CR34","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.cmet.2007.10.014","volume":"6","author":"M Miyazaki","year":"2007","unstructured":"Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X, et al. Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 2007;6:484\u201396.","journal-title":"Cell Metab"},{"key":"161_CR35","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.mce.2009.08.018","volume":"316","author":"S Galic","year":"2011","unstructured":"Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol. 2011;316:129\u201339.","journal-title":"Mol Cell Endocrinol"},{"key":"161_CR36","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3945\/jn.114.202952","volume":"145","author":"MJ LeMieux","year":"2015","unstructured":"LeMieux MJ, Kalupahana NS, Scoggin S, Moustaid-Moussa N. Eicosapentaenoic acid reduces adipocyte hypertrophy and inflammation in diet-induced obese mice in an adiposity-independent manner. J Nutr. 2015;145:411\u20137.","journal-title":"J Nutr"},{"key":"161_CR37","doi-asserted-by":"crossref","first-page":"373","DOI":"10.2165\/0129784-200808060-00004","volume":"8","author":"BA1 Golomb","year":"2008","unstructured":"Golomb BA1, Evans MA. Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism. Am J Cardiovasc Drugs. 2008;8:373\u2013418.","journal-title":"Am J Cardiovasc Drugs"},{"key":"161_CR38","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jff.2013.12.006","volume":"6","author":"P Scicchitano","year":"2014","unstructured":"Scicchitano P, Cameli M, Maiello M, Modesti PA, Muiesan ML, Novo S, et al. Nutraceuticals and dyslipidaemia: beyond the common therapeutics. J Funct Food. 2014;6:11\u201332.","journal-title":"J Funct Food"}],"container-title":["Lipids in Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12944-015-0161-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T22:40:03Z","timestamp":1653691203000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.lipidworld.com\/content\/14\/1\/155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["161"],"URL":"https:\/\/doi.org\/10.1186\/s12944-015-0161-8","relation":{},"ISSN":["1476-511X"],"issn-type":[{"value":"1476-511X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12]]},"article-number":"155"}}