{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T23:40:00Z","timestamp":1771890000156,"version":"3.50.1"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T00:00:00Z","timestamp":1527465600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T00:00:00Z","timestamp":1527465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["RO1 DK095926"],"award-info":[{"award-number":["RO1 DK095926"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004955","name":"\u00d6sterreichische Forschungsf\u00f6rderungsgesellschaft","doi-asserted-by":"publisher","award":["FWF SFB54-04"],"award-info":[{"award-number":["FWF SFB54-04"]}],"id":[{"id":"10.13039\/501100004955","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["MO1-RR00102"],"award-info":[{"award-number":["MO1-RR00102"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lipids Health Dis"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12944-018-0769-6","type":"journal-article","created":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T20:53:06Z","timestamp":1527540786000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["LpA-II:B:C:D:E: a new immunochemically-defined acute phase lipoprotein in humans"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8654-7696","authenticated-orcid":false,"given":"John D.","family":"Bagdade","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Jilma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa C.","family":"Hudgins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Alaupovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carrie E.","family":"McCurdy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,5,28]]},"reference":[{"key":"769_CR1","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1631\/jzus.2005.B1045","volume":"6","author":"E Gruys","year":"2005","unstructured":"Gruys E, Toussaint MJM, Niewold TA, Koopmans SJ. Acute phase reaction and acute phase proteins. J Zhejiang Univ Sci B. 2005;6:1045\u201356.","journal-title":"J Zhejiang Univ Sci B"},{"key":"769_CR2","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.ygeno.2015.05.001","volume":"106","author":"SW Lukowski","year":"2015","unstructured":"Lukowski SW, Fish RJ, Martin-Levilain J, Gonelle-Gispert C, Buhler LH, Maechler P, Dermitzakis ET, Neerman-Arbez M. Integrated analysis of mRNA and miRNA expression in response to interleukin-6 in hepatocytes. Genomics. 2015;106:107\u201315.","journal-title":"Genomics"},{"key":"769_CR3","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1128\/CMR.16.3.379-414.2003","volume":"16","author":"ES Van Amersfoort","year":"2003","unstructured":"Van Amersfoort ES, Van Berkel TJ, Kuiper J. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin Microbiol Rev. 2003;16:379\u2013414.","journal-title":"Clin Microbiol Rev"},{"key":"769_CR4","doi-asserted-by":"publisher","first-page":"2339","DOI":"10.1194\/jlr.M300228-JLR200","volume":"44","author":"RL Kitchens","year":"2003","unstructured":"Kitchens RL, Thompson PA, Munford RS, O'Keefe GE. Acute inflammation and infection maintain circulating phospholipid levels and enhance lipopolysaccharide binding to plasma lipoproteins. J Lipid Res. 2003;44:2339\u201348.","journal-title":"J Lipid Res"},{"issue":"Suppl 7","key":"769_CR5","doi-asserted-by":"publisher","first-page":"S498","DOI":"10.1086\/432005","volume":"41","author":"AM Barcia","year":"2005","unstructured":"Barcia AM, Harris HW. Triglyceride-rich lipoproteins as agents of innate immunity. Clin Infect Dis. 2005;41(Suppl 7):S498\u2013503.","journal-title":"Clin Infect Dis"},{"key":"769_CR6","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1172\/JCI26206","volume":"117","author":"T Vaisar","year":"2007","unstructured":"Vaisar T, Pennathur S, Green PS, Gharib SA, Hoofnagle AN, Cheung MC, Byun J, Vuletic S, Kassim S, Singh P, et al. Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J Clin Invest. 2007;117:746\u201356.","journal-title":"J Clin Invest"},{"key":"769_CR7","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1177\/09680519050110020501","volume":"11","author":"JF Berbee","year":"2005","unstructured":"Berbee JF, Havekes LM, Rensen PC. Apolipoproteins modulate the inflammatory response to lipopolysaccharide. J Endotoxin Res. 2005;11:97\u2013103.","journal-title":"J Endotoxin Res"},{"key":"769_CR8","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1194\/jlr.R300019-JLR200","volume":"45","author":"W Khovidhunkit","year":"2004","unstructured":"Khovidhunkit W, Kim MS, Memon RA, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J Lipid Res. 2004;45:1169\u201396.","journal-title":"J Lipid Res"},{"key":"769_CR9","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/0163-7827(91)90008-S","volume":"30","author":"P Alaupovic","year":"1991","unstructured":"Alaupovic P. Apolipoprotein composition as the basis for classifying plasma lipoproteins. Characterization of ApoA- and ApoB-containing lipoprotein families. Prog Lipid Res. 1991;30:105\u201338.","journal-title":"Prog Lipid Res"},{"key":"769_CR10","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s11883-003-0036-8","volume":"5","author":"P Alaupovic","year":"2003","unstructured":"Alaupovic P. The concept of apolipoprotein-defined lipoprotein families and its clinical significance. Curr Atheroscler Rep. 2003;5:459\u201367.","journal-title":"Curr Atheroscler Rep"},{"key":"769_CR11","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1161\/01.ATV.11.4.1021","volume":"11","author":"G Agnani","year":"1991","unstructured":"Agnani G, Bard JM, Candelier L, Delattre S, Fruchart JC, Clavey V. Interaction of LpB, LpB:E, LpB:C-III, and LpB:C-III:E lipoproteins with the low density lipoprotein receptor of HeLa cells. Arterioscler Thromb. 1991;11:1021\u20139.","journal-title":"Arterioscler Thromb"},{"key":"769_CR12","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1161\/01.ATV.17.4.715","volume":"17","author":"P Alaupovic","year":"1997","unstructured":"Alaupovic P, Mack WJ, Knight-Gibson C, Hodis HN. The role of triglyceride-rich lipoprotein families in the progression of atherosclerotic lesions as determined by sequential coronary angiography from a controlled clinical trial. Arterioscler Thromb Vasc Biol. 1997;17:715\u201322.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"769_CR13","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1161\/01.ATV.0000066131.01313.EB","volume":"23","author":"SJ Lee","year":"2003","unstructured":"Lee SJ, Campos H, Moye LA, Sacks FM. LDL containing apolipoprotein CIII is an independent risk factor for coronary events in diabetic patients. Arterioscler Thromb Vasc Biol. 2003;23:853\u20138.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"769_CR14","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1161\/01.CIR.102.16.1886","volume":"102","author":"FM Sacks","year":"2000","unstructured":"Sacks FM, Alaupovic P, Moye LA, Cole TG, Sussex B, Stampfer MJ, Pfeffer MA, Braunwald E. VLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the cholesterol and recurrent events (CARE) trial. Circulation. 2000;102:1886\u201392.","journal-title":"Circulation"},{"key":"769_CR15","doi-asserted-by":"publisher","first-page":"96","DOI":"10.2174\/187221309788489779","volume":"3","author":"DS Wheeler","year":"2009","unstructured":"Wheeler DS, Zingarelli B, Wheeler WJ, Wong HR. Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response. Recent Patents Inflamm Allergy Drug Discov. 2009;3:96\u2013112.","journal-title":"Recent Patents Inflamm Allergy Drug Discov"},{"key":"769_CR16","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/S0171-2985(11)80353-0","volume":"187","author":"GD Martich","year":"1993","unstructured":"Martich GD, Boujoukos AJ, Suffredini AF. Response of man to endotoxin. Immunobiology. 1993;187:403\u201316.","journal-title":"Immunobiology"},{"key":"769_CR17","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/0026-0495(88)90120-5","volume":"37","author":"K Sammalkorpi","year":"1988","unstructured":"Sammalkorpi K, Valtonen V, Kerttula Y, Nikkil\u00e4 E, Taskinen M-R. Changes in serum lipoprotein pattern induced by acute infections. Metabolism. 1988;37:859\u201365.","journal-title":"Metabolism"},{"key":"769_CR18","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1097\/00003246-200108000-00011","volume":"29","author":"BR Gordon","year":"2001","unstructured":"Gordon BR, Parker TS, Levine DM, Saal SD, Wang JC, Sloan BJ, Barie PS, Rubin AL. Relationship of hypolipidemia to cytokine concentrations and outcomes in critically ill surgical patients. Crit Care Med. 2001;29:1563\u20138.","journal-title":"Crit Care Med"},{"key":"769_CR19","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1194\/jlr.M200440-JLR200","volume":"44","author":"LC Hudgins","year":"2003","unstructured":"Hudgins LC, Parker TS, Levine DM, Gordon BR, Saal SD, Jiang XC, Seidman CE, Tremaroli JD, Lai J, Rubin AL. A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers. J Lipid Res. 2003;44:1489\u201398.","journal-title":"J Lipid Res"},{"key":"769_CR20","doi-asserted-by":"publisher","first-page":"449","DOI":"10.3109\/00365513.2011.585404","volume":"71","author":"J Bagdade","year":"2011","unstructured":"Bagdade J, Pedersen BK, Schwenke D, Saremi A, Alaupovic P. Acute effects of interleukin-6 infusion on apo-B-containing lipoprotein subclasses in humans. Scand J Clin Lab Invest. 2011;71:449\u201355.","journal-title":"Scand J Clin Lab Invest"},{"key":"769_CR21","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1093\/chromsci\/13.9.423","volume":"13","author":"A Kuksis","year":"1975","unstructured":"Kuksis A, Myher JJ, Marai L, Geher K. Determination of plasma lipid profiles by automated gas chromatography and computerized data analysis. J Chromatogr Sci. 1975;13:423\u201330.","journal-title":"J Chromatogr Sci"},{"key":"769_CR22","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","author":"WT Friedewald","year":"1972","unstructured":"Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499\u2013502.","journal-title":"Clin Chem"},{"key":"769_CR23","doi-asserted-by":"publisher","first-page":"739","DOI":"10.3109\/00365518709168939","volume":"47","author":"P Riepponen","year":"1987","unstructured":"Riepponen P, Marniemi J, Rautaoja T. Immunoturbidimetric determination of apolipoproteins A-1 and B in serum. Scand J Clin Lab Invest. 1987;47:739\u201344.","journal-title":"Scand J Clin Lab Invest"},{"key":"769_CR24","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1111\/j.1365-2362.2008.02001.x","volume":"38","author":"DM Lee","year":"2008","unstructured":"Lee DM, Alaupovic P, Knight-Gibson C, Bagdade JD. Apolipoprotein-B subclasses as acceptors of cholesteryl esters transferred by CETP. Eur J Clin Investig. 2008;38:734\u201342.","journal-title":"Eur J Clin Investig"},{"key":"769_CR25","first-page":"573","volume":"26","author":"W Marz","year":"1988","unstructured":"Marz W, Trommlitz M, Gross W. Differential turbidimetric assay for subpopulations of lipoproteins containing apolipoprotein A-I. J Clin Chem Clin Biochem. 1988;26:573\u20138.","journal-title":"J Clin Chem Clin Biochem"},{"key":"769_CR26","volume-title":"Statistical methods","author":"GW Snedecor","year":"1980","unstructured":"Snedecor GW, Cochran WG. Statistical methods. 7th ed. Ames, Iowa: Iowa State University Press; 1980.","edition":"7"},{"key":"769_CR27","doi-asserted-by":"publisher","first-page":"4545","DOI":"10.1182\/blood-2003-03-0713","volume":"103","author":"O Aras","year":"2004","unstructured":"Aras O, Shet A, Bach RR, Hysjulien JL, Slungaard A, Hebbel RP, Escolar G, Jilma B, Key NS. Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia. Blood. 2004;103:4545\u201353.","journal-title":"Blood"},{"key":"769_CR28","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1097\/01.CCM.0000059724.08290.51","volume":"31","author":"HJ van Leeuwen","year":"2003","unstructured":"van Leeuwen HJ, Heezius EC, Dallinga GM, van Strijp JA, Verhoef J, van Kessel KP. Lipoprotein metabolism in patients with severe sepsis. Crit Care Med. 2003;31:1359\u201366.","journal-title":"Crit Care Med"},{"key":"769_CR29","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1056\/NEJM199902113400607","volume":"340","author":"C Gabay","year":"1999","unstructured":"Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999;340:448\u201354.","journal-title":"N Engl J Med"},{"key":"769_CR30","first-page":"789298","volume":"2015","author":"SH Lee","year":"2015","unstructured":"Lee SH, Park MS, Park BH, Jung WJ, Lee IS, Kim SY, Kim EY, Jung JY, Kang YA, Kim YS, et al. Prognostic implications of serum lipid metabolism over time during Sepsis. Biomed Res Int. 2015;2015:789298.","journal-title":"Biomed Res Int"},{"key":"769_CR31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0022-2275(20)42239-4","volume":"32","author":"P Alaupovic","year":"1991","unstructured":"Alaupovic P, Knight-Gibson C, Wang CS, Downs D, Koren E, Brewer HB Jr, Gregg RE. Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with tangier disease and type V hyperlipoproteinemia. J Lipid Res. 1991;32:9\u201319.","journal-title":"J Lipid Res"},{"key":"769_CR32","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.atherosclerosis.2015.05.013","volume":"241","author":"NK Desai","year":"2015","unstructured":"Desai NK, Ooi EM, Mitchell PD, Furtado J, Sacks FM. Metabolism of apolipoprotein A-II containing triglyceride rich ApoB lipoproteins in humans. Atherosclerosis. 2015;241:326\u201333.","journal-title":"Atherosclerosis"},{"key":"769_CR33","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1172\/JCI117775","volume":"95","author":"SL Jiang","year":"1995","unstructured":"Jiang SL, Samols D, Rzewnicki D, Macintyre SS, Greber I, Sipe J, Kushner I. Kinetic modeling and mathematical analysis indicate that acute phase gene expression in Hep 3B cells is regulated by both transcriptional and posttranscriptional mechanisms. J Clin Invest. 1995;95:1253\u201361.","journal-title":"J Clin Invest"},{"key":"769_CR34","unstructured":"Feingold KR, Grunfeld C. The effect of inflammation and infection on lipids and lipoproteins. In Endotext. Edited by De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, et al. South Dartmouth (MA); 2000."},{"issue":"Suppl 3","key":"769_CR35","doi-asserted-by":"publisher","first-page":"S462","DOI":"10.1086\/315611","volume":"181","author":"W Khovidhunkit","year":"2000","unstructured":"Khovidhunkit W, Memon RA, Feingold KR, Grunfeld C. Infection and inflammation-induced proatherogenic changes of lipoproteins. J Infect Dis. 2000;181(Suppl 3):S462\u201372.","journal-title":"J Infect Dis"},{"key":"769_CR36","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1177\/1753425908099171","volume":"14","author":"PA Thompson","year":"2008","unstructured":"Thompson PA, Berbee JF, Rensen PC, Kitchens RL. Apolipoprotein A-II augments monocyte responses to LPS by suppressing the inhibitory activity of LPS-binding protein. Innate Immun. 2008;14:365\u201374.","journal-title":"Innate Immun"},{"key":"769_CR37","doi-asserted-by":"publisher","first-page":"2983","DOI":"10.1002\/eji.201242564","volume":"42","author":"S Sigel","year":"2012","unstructured":"Sigel S, Bunk S, Meergans T, Doninger B, Stich K, Stulnig T, Derfler K, Hoffmann J, Deininger S, von Aulock S, Knapp S. Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune responses in humans and mice. Eur J Immunol. 2012;42:2983\u20139.","journal-title":"Eur J Immunol"},{"key":"769_CR38","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1161\/01.ATV.0000217957.93135.c2","volume":"26","author":"XZ Ruan","year":"2006","unstructured":"Ruan XZ, Moorhead JF, Tao JL, Ma KL, Wheeler DC, Powis SH, Varghese Z. Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines. Arterioscler Thromb Vasc Biol. 2006;26:1150\u20135.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"769_CR39","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1161\/01.ATV.19.3.472","volume":"19","author":"MC Jong","year":"1999","unstructured":"Jong MC, Hofker MH, Havekes LM. Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3. Arterioscler Thromb Vasc Biol. 1999;19:472\u201384.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"769_CR40","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1096\/fj.05-5639fje","volume":"20","author":"JF Berbee","year":"2006","unstructured":"Berbee JF, van der Hoogt CC, Kleemann R, Schippers EF, Kitchens RL, van Dissel JT, Bakker-Woudenberg IA, Havekes LM, Rensen PC. Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in gram-negative sepsis. FASEB J. 2006;20:2162\u20134.","journal-title":"FASEB J"},{"key":"769_CR41","doi-asserted-by":"publisher","first-page":"6","DOI":"10.5551\/jat.E607","volume":"16","author":"A Kawakami","year":"2009","unstructured":"Kawakami A, Yoshida M. Apolipoprotein CIII links dyslipidemia with atherosclerosis. J Atheroscler Thromb. 2009;16:6\u201311.","journal-title":"J Atheroscler Thromb"},{"key":"769_CR42","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1021\/bi00648a010","volume":"15","author":"WJ McConathy","year":"1976","unstructured":"McConathy WJ, Alaupovic P. Studies on the isolation and partial characterization of apolipoprotein D and lipoprotein D of human plasma. Biochemistry. 1976;15:515\u201320.","journal-title":"Biochemistry"},{"key":"769_CR43","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1161\/CIRCRESAHA.113.302943","volume":"113","author":"AM Fogelman","year":"2013","unstructured":"Fogelman AM, Reddy ST, Navab M. Protection against ischemia\/reperfusion injury by high-density lipoprotein and its components. Circ Res. 2013;113:1281\u20132.","journal-title":"Circ Res"},{"key":"769_CR44","doi-asserted-by":"publisher","first-page":"939","DOI":"10.2298\/ABS1303939K","volume":"65","author":"AM Kaneva","year":"2013","unstructured":"Kaneva AM, Potolitsyna NN, Bolijo ER. Concentration of apolipoprotein-E in high-density lipoproteins of human plasma. Arch Biol Sci. 2013;65:939\u201344.","journal-title":"Arch Biol Sci"},{"key":"769_CR45","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.amjsurg.2009.10.017","volume":"200","author":"K Chuang","year":"2010","unstructured":"Chuang K, Elford EL, Tseng J, Leung B, Harris HW. An expanding role for apolipoprotein E in sepsis and inflammation. Am J Surg. 2010;200:391\u20137.","journal-title":"Am J Surg"},{"key":"769_CR46","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1146\/annurev.genom.1.1.507","volume":"1","author":"RW Mahley","year":"2000","unstructured":"Mahley RW, Rall SC Jr. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet. 2000;1:507\u201337.","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"769_CR47","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1002\/art.33425","volume":"64","author":"N Knowlton","year":"2012","unstructured":"Knowlton N, Wages JA, Centola MB, Giles J, Bathon J, Quiroga C, Alaupovic P. Apolipoprotein B-containing lipoprotein subclasses as risk factors for cardiovascular disease in patients with rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64:993\u20131000.","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"769_CR48","doi-asserted-by":"crossref","unstructured":"Hovingh GK, Kuivenhoven JA, Bisoendial RJ, Groen AK, van Dam M, van Tol A, Wellington C, Hayden MR, Smelt AH, Kastelein JJ. HDL deficiency and atherosclerosis: lessons from tangier disease. J Intern Med. 2004;255:299\u2013301.","DOI":"10.1046\/j.0954-6820.2003.01256.x"},{"key":"769_CR49","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1097\/MOL.0000000000000333","volume":"27","author":"KR Feingold","year":"2016","unstructured":"Feingold KR, Grunfeld C. Effect of inflammation on HDL structure and function. Curr Opin Lipidol. 2016;27:521\u201330.","journal-title":"Curr Opin Lipidol"},{"key":"769_CR50","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1161\/ATVBAHA.108.178681","volume":"29","author":"A Jahangiri","year":"2009","unstructured":"Jahangiri A, de Beer MC, Noffsinger V, Tannock LR, Ramaiah C, Webb NR, van der Westhuyzen DR, de Beer FC. HDL remodeling during the acute phase response. Arterioscler Thromb Vasc Biol. 2009;29:261\u20137.","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"769_CR51","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1194\/jlr.M800172-JLR200","volume":"49","author":"L Li","year":"2008","unstructured":"Li L, Thompson PA, Kitchens RL. Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors. J Lipid Res. 2008;49:1782\u201393.","journal-title":"J Lipid Res"}],"container-title":["Lipids in Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12944-018-0769-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12944-018-0769-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12944-018-0769-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T12:07:18Z","timestamp":1661342838000},"score":1,"resource":{"primary":{"URL":"https:\/\/lipidworld.biomedcentral.com\/articles\/10.1186\/s12944-018-0769-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,28]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["769"],"URL":"https:\/\/doi.org\/10.1186\/s12944-018-0769-6","relation":{},"ISSN":["1476-511X"],"issn-type":[{"value":"1476-511X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,28]]},"assertion":[{"value":"13 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 May 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The protocol was approved by the Ethical Committee(s) of the Medical University of Vienna, Austria and of Copenhagen and Fredriksberg Communities, DK and by the Institutional Review Boards of Rockefeller University and the Oklahoma Medical Research Foundation. Subjects were informed about the possible risks and discomfort before giving their written consent to participate.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"127"}}