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Intracranial and extracranial arteries were evaluated for atherosclerotic stenosis using digital subtraction angiography or computed tomography angiography. Lipid ratios [total cholesterol (TC)\/high-density lipoprotein-cholesterol (HDL-C), triglycerides (TG)\/HDL-C, low-density lipoprotein-cholesterol (LDL-C)\/HDL-C, non-high-density lipoprotein-cholesterol (non-HDL-C)\/HDL-C, remnant cholesterol (RC)\/HDL-C, apolipoprotein B (apo B)\/apolipoprotein A-I (apo A-I), and apo B\/HDL-C] were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The TC\/HDL-C, LDL-C\/HDL-C, RC\/HDL-C, non-HDL-C\/HDL-C, apo B\/HDL-C and apo B\/apo A-I ratios (all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05) were significantly associated with ICAS but not with extracranial atherosclerotic stenosis after adjustment for confounding factors. Receiver operating characteristic (ROC) curves analysis revealed that the apo B\/apo A-I ratio had the largest area under the ROC curve (AUC) among lipid levels alone and for lipid ratios (AUC\u2009=\u20090.588). Lipid ratios had higher AUC values than those for lipid levels alone for the identification of ICAS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The TC\/HDL-C, LDL-C\/HDL-C, RC\/HDL-C, non-HDL-C\/HDL-C apo B\/HDL-C, and apo B\/apo A-I ratios were significantly related to ICAS risk. Compared with the other variables tested, the apo B\/apo A-I ratio appeared to be a better discriminator for identifying ICAS risk in stroke patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12944-020-01336-1","type":"journal-article","created":{"date-parts":[[2020,7,4]],"date-time":"2020-07-04T09:03:42Z","timestamp":1593853422000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Importance of lipid ratios for predicting intracranial atherosclerotic stenosis"],"prefix":"10.1186","volume":"19","author":[{"given":"Wen-Song","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Qing","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-Chen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Jun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Yang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-En","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,4]]},"reference":[{"key":"1336_CR1","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1016\/S0140-6736(13)61088-0","volume":"383","author":"AI Qureshi","year":"2014","unstructured":"Qureshi AI, Caplan LR. 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