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It is often associated with dyslipidemia and other risk factors of cardiovascular diseases (CVD). This study was aimed to evaluate dietary intervention effects with canola and olive oils compared to sunflower oil on lipid profile and fatty liver severity among women with PCOS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This study was a 10-week intervention including 72 women with PCOS. Patients were randomly assigned to three groups for receiving 25\u2009g\/day canola, olive, or sunflower oils for 10\u2009weeks. The primary and secondary outcomes were to assess changes in lipid profile and in fatty liver severity, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>\n                      At the end of the study, 72 patients with a mean age of 29.31 were analysed. Canola oil consumption resulted in a significant reduction in serum levels of TG (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002) and TC\/HDL (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.021), LDL\/HDL (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.047), and TG\/HDL (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001) ratios, however, there was no significant reduction in lipid profile following olive oil consumption. Canola (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and olive oils (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.005) could significantly reduce the fatty liver grade. Moreover, HOMA-IR in both canola (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) and olive (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.004) groups was significantly decreased.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In total, compared to olive and sunflower oils, significant improvements in lipid profile, liver function, and HOMA-IR were observed following canola oil consumption in women with PCOS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>\n                      IR.MUI.RESEARCH.REC.1397.315. Registered 30 JUNE 2019 - Retrospectively registered,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.irct.ir\/trial\/38684\">https:\/\/www.irct.ir\/trial\/38684<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12944-021-01433-9","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T04:42:23Z","timestamp":1611895343000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a randomized controlled trial"],"prefix":"10.1186","volume":"20","author":[{"given":"Maryam","family":"Yahay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Heidari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Allameh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0074-4080","authenticated-orcid":false,"given":"Reza","family":"Amani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,29]]},"reference":[{"issue":"5","key":"1433_CR1","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/nrendo.2018.24","volume":"14","author":"HF Escobar-Morreale","year":"2018","unstructured":"Escobar-Morreale HF. 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The protocol of present study was reviewed and approved by Medical Ethics Committee at Isfahan University of Medical Sciences, Iran (ethics registration number: IR.MUI.RESEARCH.REC.1397.315) which registered at Iranian Registry of Clinical Trials (approval code: 38684).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"7"}}