{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T04:30:10Z","timestamp":1787632210075,"version":"build-2736575974"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82160207"],"award-info":[{"award-number":["82160207"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Technology Plan of Jiangxi Provincial Health and Health Commission","award":["202130156"],"award-info":[{"award-number":["202130156"]}]},{"name":"the Science and Key Projects of Jiangxi Youth Science Fund","award":["20202ACBL216008"],"award-info":[{"award-number":["20202ACBL216008"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lipids Health Dis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Explore the relationship between the triglyceride-glucose (TyG) index, along with its derivative indices, and the prevalence of cataracts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 20,497 participants in the 2005\u20132008 National Health and Nutrition Examination Survey (NHANES) were compiled. A final total of 4,499 individuals met the eligibility criteria. Cataract presence was assessed through a self-reported history of cataract surgery. The TyG index and its derivatives\u2014TyG-waist-to-height ratio (WHtR), TyG-neutrophil-to-lymphocyte ratio (NLR), TyG-monocyte-to-lymphocyte ratio (MLR), TyG-log platelet-to-lymphocyte ratio (lgPLR), TyG-log systemic inflammation index (lgSII), and TyG-systemic inflammation response index (SIRI)\u2014were calculated. Statistical analyses included multivariable logistic regression, restricted cubic spline (RCS) curves for nonlinear relationships, and receiver operating characteristic (ROC) analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Higher TyG indices were significantly associated with cataract presence (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Specifically, TyG-WHtR, TyG-NLR, TyG-lgPLR, TyG-lgSII, and TyG-SIRI exhibited positive correlations with cataract prevalence, even after adjustment for potential confounders (odds ratio [OR]\u2009=\u20091.17; 95% confidence interval [CI]: 1.01, 1.37;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0403; [OR]\u2009=\u20091.01; 95% [CI]: 1.00, 1.02;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0258; [OR]\u2009=\u20091.08; 95% [CI]: 1.01, 1.16;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0223; [OR]\u2009=\u20091.08; 95% [CI]: 1.03, 1.14;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001; [OR]\u2009=\u20091.02; 95% [CI]: 1.00, 1.04;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.0120). Furthermore, the stratified analysis showed that in the 61\u201385 age group, TyG-lgPLR and TyG-lgSII remained positively associated with cataract prevalence ([OR]\u2009=\u20091.09; 95% [CI]: 1.01, 1.17;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.024; [OR]\u2009=\u20091.08; 95% [CI]: 1.02, 1.13;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.005). RCS analysis revealed a linear association between these indices and cataracts, with no apparent threshold effect. ROC analysis indicated that TyG-MLR demonstrated the highest predictive ability for cataract presence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The study results indicate a positive association between TyG-related indicators and cataract the prevalence of cataracts in middle-aged and elderly individuals, suggesting that these markers may serve as practical biomarkers for identifying high-risk individuals. Early detection and management of metabolic and inflammatory factors could contribute to effective preventive strategies for cataract development in the elderly population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12944-025-02470-4","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T03:11:20Z","timestamp":1739502680000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Association of triglyceride-glucose index and derived indices with cataract in middle-aged and elderly Americans: NHANES 2005\u20132008"],"prefix":"10.1186","volume":"24","author":[{"given":"Bin","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben-Liang","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin-Yi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Yu","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Chong","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Li","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo-Er","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-rong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"key":"2470_CR1","unstructured":"Global. regional, national burden and gender disparity of cataract: findings from the global burden of disease study 2019."},{"issue":"10","key":"2470_CR2","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1016\/j.jcrs.2019.06.006","volume":"45","author":"T Matsumura","year":"2019","unstructured":"Matsumura T, Takamura Y, Makita J, Kobori A, Inatani M. Influence of sclerotomy size on intraocular lens tilt after intrascleral intraocular lens fixation. J Cataract Refract Surg. 2019;45(10):1446\u201351. https:\/\/doi.org\/10.1016\/j.jcrs.2019.06.006","journal-title":"J Cataract Refract Surg"},{"issue":"9","key":"2470_CR3","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.3390\/antiox12091783","volume":"12","author":"WK Subczynski","year":"2023","unstructured":"Subczynski WK, Pasenkiewicz-Gierula M, Widomska J. Protecting the Eye Lens from oxidative stress through Oxygen Regulation. Antioxid (Basel Switzerland). 2023;12(9):1783. https:\/\/doi.org\/10.3390\/antiox12091783","journal-title":"Antioxid (Basel Switzerland)"},{"issue":"10","key":"2470_CR4","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.3390\/metabo13101100","volume":"13","author":"JV Greiner","year":"2023","unstructured":"Greiner JV, Glonek T. Adenosine Triphosphate (ATP) and protein aggregation in Age-Related Vision-threatening ocular diseases. Metabolites. 2023;13(10):1100. https:\/\/doi.org\/10.3390\/metabo13101100","journal-title":"Metabolites"},{"key":"2470_CR5","doi-asserted-by":"publisher","first-page":"104154","DOI":"10.1016\/j.ebiom.2022.104154","volume":"82","author":"SC Larsson","year":"2022","unstructured":"Larsson SC, Burgess S. Appraising the causal role of smoking in multiple diseases: a systematic review and meta-analysis of mendelian randomization studies. EBioMedicine. 2022;82:104154. https:\/\/doi.org\/10.1016\/j.ebiom.2022.104154","journal-title":"EBioMedicine"},{"issue":"9","key":"2470_CR6","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.3390\/nu14091684","volume":"14","author":"JH Chang","year":"2022","unstructured":"Chang JH, Chen IH, Geng JH, Wu PY, Huang JC, Chen SC. Metabolic syndrome is Associated with Cataract in a large Taiwanese Population Study. Nutrients. 2022;14(9):1684. https:\/\/doi.org\/10.3390\/nu14091684","journal-title":"Nutrients"},{"issue":"5","key":"2470_CR7","doi-asserted-by":"publisher","first-page":"2397","DOI":"10.1167\/iovs.10-6373","volume":"52","author":"C Sabanayagam","year":"2011","unstructured":"Sabanayagam C, Wang JJ, Mitchell P, Tan AG, Tai ES, Aung T, Saw SM, Wong TY. Metabolic syndrome components and age-related cataract: the Singapore malay eye study. Investig Ophthalmol Vis Sci. 2011;52(5):2397\u2013404. https:\/\/doi.org\/10.1167\/iovs.10-6373","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"11","key":"2470_CR8","doi-asserted-by":"publisher","first-page":"e70157","DOI":"10.1002\/hsr2.70157","volume":"7","author":"XX Qiu","year":"2024","unstructured":"Qiu XX, Chen YL, Wang XK, Wang RH. Vital Predictive and prognostic roles of triglyceride-glucose index in Women with Acute myocardial infarction: a retrospective cohort study. Health Sci Rep. 2024;7(11):e70157. https:\/\/doi.org\/10.1002\/hsr2.70157","journal-title":"Health Sci Rep"},{"key":"2470_CR9","doi-asserted-by":"publisher","first-page":"132663","DOI":"10.1016\/j.ijcard.2024.132663","volume":"418","author":"A Avagimyan","year":"2024","unstructured":"Avagimyan A, Pogosova N, Fogacci F, Aghajanova E, Djndoyan Z, Patoulias D, Sasso LL, Bernardi M, Faggiano A, Mohammadifard N, Neglia D, Carugo S, Cicero A, Rizzo M, Biondi-Zoccai G, De Caterina R, Sarrafzadegan N. Triglyceride-glucose index (TyG) as a novel biomarker in the era of cardiometabolic medicine. Int J Cardiol. 2024;418:132663. https:\/\/doi.org\/10.1016\/j.ijcard.2024.132663. Advance online publication.","journal-title":"Int J Cardiol"},{"key":"2470_CR10","doi-asserted-by":"publisher","first-page":"1416634","DOI":"10.3389\/fendo.2024.1416634","volume":"15","author":"C Cao","year":"2024","unstructured":"Cao C, Hu H, Xiao P, Zan Y, Chang X, Han Y, Zhang X, Wang Y. Nonlinear relationship between triglyceride-glucose index and the risk of prediabetes and diabetes: a secondary retrospective cohort study. Front Endocrinol. 2024;15:1416634. https:\/\/doi.org\/10.3389\/fendo.2024.1416634","journal-title":"Front Endocrinol"},{"key":"2470_CR11","doi-asserted-by":"publisher","first-page":"1444049","DOI":"10.3389\/fnut.2024.1444049","volume":"11","author":"Y Shen","year":"2024","unstructured":"Shen Y, Zhu Z, Bi X, Shen Y, Shen A, Deng B, He Y, Wang W, Ding F. Association between insulin resistance indices and kidney stones: results from the 2015\u20132018 National Health and Nutrition Examination Survey. Front Nutr. 2024;11:1444049. https:\/\/doi.org\/10.3389\/fnut.2024.1444049","journal-title":"Front Nutr"},{"issue":"1","key":"2470_CR12","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1186\/s12944-024-02277-9","volume":"23","author":"Y Chen","year":"2024","unstructured":"Chen Y, Xie K, Han Y, Ju H, Sun J, Zhao X. The association between triglyceride-glucose index and its combination with systemic inflammation indicators and all-cause and cardiovascular mortality in the general US population: NHANES 1999\u20132018. Lipids Health Dis. 2024;23(1):289. https:\/\/doi.org\/10.1186\/s12944-024-02277-9","journal-title":"Lipids Health Dis"},{"key":"2470_CR13","doi-asserted-by":"publisher","first-page":"1481620","DOI":"10.3389\/fmed.2024.1481620","volume":"11","author":"J Wang","year":"2024","unstructured":"Wang J, Chen S, Chen X, Qin C, Hu J, Zeng X, Luo H, Yang P, Luo H, Yuan C, Shi R, Wang D. Higher triglyceride glucose-waist height ratio index is associated with higher prevalence of gallstone: a population-based study. Front Med. 2024;11:1481620. https:\/\/doi.org\/10.3389\/fmed.2024.1481620","journal-title":"Front Med"},{"key":"2470_CR14","doi-asserted-by":"publisher","first-page":"e17998","DOI":"10.7717\/peerj.17998","volume":"12","author":"Y Gong","year":"2024","unstructured":"Gong Y, Wei Q, Luo L, Qiu W, Jiang Y. A lipidomic study on the lens epithelial cells of patients with age related cataracts. PeerJ. 2024;12:e17998. https:\/\/doi.org\/10.7717\/peerj.17998","journal-title":"PeerJ"},{"issue":"5","key":"2470_CR15","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1093\/bjd\/ljae291","volume":"191","author":"H Wang","year":"2024","unstructured":"Wang H, Wu Y, Bassetti JA, Wang Z, Oza VS, Rangu SA, McGivern B, Peng S, Liang L, Huang S, Gong Z, Xu Z, Lin Z. A gain-of-function variant in SREBF1 causes generalized skin hyperpigmentation with congenital cataracts. Br J Dermatol. 2024;191(5):805\u201315. https:\/\/doi.org\/10.1093\/bjd\/ljae291","journal-title":"Br J Dermatol"},{"issue":"1","key":"2470_CR16","doi-asserted-by":"publisher","first-page":"18161","DOI":"10.1038\/s41598-023-45088-1","volume":"13","author":"M Takashima","year":"2023","unstructured":"Takashima M, Taniguchi K, Nagaya M, Yamamura S, Takamura Y, Inatani M, Oki M. Gene profiles and mutations in the development of cataracts in the ICR rat model of hereditary cataracts. Sci Rep. 2023;13(1):18161. https:\/\/doi.org\/10.1038\/s41598-023-45088-1","journal-title":"Sci Rep"},{"issue":"11","key":"2470_CR17","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1167\/tvst.11.11.5","volume":"11","author":"J Wang","year":"2022","unstructured":"Wang J, Zhang Y, Li W, Zhou F, Li J. Changes in the lipid Profile of aqueous humor from Diabetic Cataract patients. Translational Vis Sci Technol. 2022;11(11):5. https:\/\/doi.org\/10.1167\/tvst.11.11.5","journal-title":"Translational Vis Sci Technol"},{"issue":"3","key":"2470_CR18","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.3390\/ijms25031894","volume":"25","author":"R Fiolka","year":"2024","unstructured":"Fiolka R, Wyl\u0119ga\u0142a E, Toborek M, Szkodny D, Czuba Z, Wyl\u0119ga\u0142a A. Fuch\u2019s endothelial corneal dystrophy in cataract patients is Associated with elevated levels of inflammatory chemokines, but not growth factors, in the aqueous humor. Int J Mol Sci. 2024;25(3):1894. https:\/\/doi.org\/10.3390\/ijms25031894","journal-title":"Int J Mol Sci"},{"issue":"10","key":"2470_CR19","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.3390\/antiox13101249","volume":"13","author":"J Li","year":"2024","unstructured":"Li J, Buonfiglio F, Zeng Y, Pfeiffer N, Gericke A. Oxidative stress in cataract formation: is there a Treatment Approach on the Horizon? Antioxid (Basel Switzerland). 2024;13(10):1249. https:\/\/doi.org\/10.3390\/antiox13101249","journal-title":"Antioxid (Basel Switzerland)"},{"issue":"10","key":"2470_CR20","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.3390\/antiox13101207","volume":"13","author":"VP Kumar","year":"2024","unstructured":"Kumar VP, Kong Y, Dolland R, Brown SR, Wang K, Dolland D, Mu D, Brown ML. Exploring angiotensin II and oxidative stress in Radiation-Induced cataract formation: potential for therapeutic intervention. Antioxid (Basel Switzerland). 2024;13(10):1207. https:\/\/doi.org\/10.3390\/antiox13101207","journal-title":"Antioxid (Basel Switzerland)"},{"issue":"10","key":"2470_CR21","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.3390\/antiox13101193","volume":"13","author":"JC Lim","year":"2024","unstructured":"Lim JC, Jiang L, Lust NG, Donaldson PJ. Minimizing oxidative stress in the Lens: alternative measures for elevating glutathione in the Lens to protect against cataract. Antioxid (Basel Switzerland). 2024;13(10):1193. https:\/\/doi.org\/10.3390\/antiox13101193","journal-title":"Antioxid (Basel Switzerland)"},{"key":"2470_CR22","doi-asserted-by":"publisher","first-page":"1405033","DOI":"10.3389\/fnut.2024.1405033","volume":"11","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Qin X, Xu T, Chu F, He B. Research progress on the correlation between cataract occurrence and nutrition. Front Nutr. 2024;11:1405033. https:\/\/doi.org\/10.3389\/fnut.2024.1405033","journal-title":"Front Nutr"},{"issue":"3","key":"2470_CR23","doi-asserted-by":"publisher","first-page":"e56","DOI":"10.1016\/j.diabres.2010.06.002","volume":"89","author":"GQ Yang","year":"2010","unstructured":"Yang GQ, Wang BA, Zhao WR, Gu WJ, Lui ZH, Dou JT, Mu YM, Lu JM. Clinical and genetic analysis of the insulin receptor gene in a Chinese patient with extreme insulin resistance. Diabetes Res Clin Pract. 2010;89(3):e56\u20138. https:\/\/doi.org\/10.1016\/j.diabres.2010.06.002","journal-title":"Diabetes Res Clin Pract"},{"issue":"1","key":"2470_CR24","doi-asserted-by":"publisher","first-page":"26093","DOI":"10.1038\/s41598-024-76530-7","volume":"14","author":"Z Huang","year":"2024","unstructured":"Huang Z, Tang R, Ding Y, Wang W, Du X, Wang X, Li Z, Xiao J, Wang X. Association of the triglyceride glucose index with myocardial ischemia in patients with minimal to moderate coronary artery disease. Sci Rep. 2024;14(1):26093. https:\/\/doi.org\/10.1038\/s41598-024-76530-7","journal-title":"Sci Rep"},{"key":"2470_CR25","doi-asserted-by":"publisher","first-page":"1469055","DOI":"10.3389\/fendo.2024.1469055","volume":"15","author":"JP Xu","year":"2024","unstructured":"Xu JP, Peng XQ, Guo LH, Zhao XJ, Chen MS, Mai XY, Tan JW, Chen Q, Zeng RX, Zhang MZ. The associations of the triglyceride-glucose index and its combination with blood pressure on cardiovascular and all-cause mortality in hypertension: a national study. Front Endocrinol. 2024;15:1469055. https:\/\/doi.org\/10.3389\/fendo.2024.1469055","journal-title":"Front Endocrinol"},{"key":"2470_CR26","doi-asserted-by":"publisher","unstructured":"Zhang Y, Zhou J, Shen W, Grzybowski A, Jin K, Ye J. Association between dietary inflammation index and cataract: a population-based study from NHANES 2005\u20132008. Front Nutr. 2024;11(1379317). https:\/\/doi.org\/10.3389\/fnut.2024.1379317","DOI":"10.3389\/fnut.2024.1379317"},{"key":"2470_CR27","doi-asserted-by":"publisher","first-page":"155189","DOI":"10.1016\/j.cyto.2020.155189","volume":"134","author":"JS Zhang","year":"2020","unstructured":"Zhang JS, Wang JD, Zhu GY, Yusufu M, Xiong Y, Li J, Cao K, Jin SS, He HL, Sun XL, Wan XH. The high expression of the pain-related inflammatory factors in the eyes of cataract patients infected with hepatitis B virus. Cytokine. 2020;134:155189. https:\/\/doi.org\/10.1016\/j.cyto.2020.155189","journal-title":"Cytokine"},{"issue":"10","key":"2470_CR28","doi-asserted-by":"publisher","first-page":"e70001","DOI":"10.1111\/1753-0407.70001","volume":"16","author":"H Wang","year":"2024","unstructured":"Wang H, He S, Wang J, Qian X, Zhang B, Yang Z, Chen B, Li G, Gong Q, Da Qing Diabetes Prevention Outcome Study Group. Assessing and predicting type 2 diabetes risk with triglyceride glucose-body mass index in the Chinese nondiabetic population-data from long-term follow-up of Da Qing IGT and Diabetes Study. J Diabetes. 2024;16(10):e70001. https:\/\/doi.org\/10.1111\/1753-0407.70001","journal-title":"J Diabetes"},{"key":"2470_CR29","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-024-03947-5","author":"L Yang","year":"2024","unstructured":"Yang L, Feng Y, Wang Y, Liu C, Gao D. Relationship between four insulin resistance surrogates and regression to normoglycemia from prediabetes among Chinese adults: a longitudinal Cohort Study. Endocrine. 2024. https:\/\/doi.org\/10.1007\/s12020-024-03947-5. https:\/\/doi.org\/10.1007\/s12020-024-03947-5. Advance online publication.","journal-title":"Endocrine"},{"issue":"1","key":"2470_CR30","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1186\/s12933-024-02385-x","volume":"23","author":"C Tian","year":"2024","unstructured":"Tian C, Chen Y, Xu B, Tan X, Zhu Z. Association of triglyceride-glucose index with the risk of incident aortic dissection and aneurysm: a large-scale prospective cohort study in UK Biobank. Cardiovasc Diabetol. 2024;23(1):282. https:\/\/doi.org\/10.1186\/s12933-024-02385-x","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"2470_CR31","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1186\/s12944-024-02403-7","volume":"23","author":"F Zhang","year":"2024","unstructured":"Zhang F, Sun Y, Bai Y, Wu R, Yang H. Association of triglyceride-glucose index and diabesity: evidence from a national longitudinal study. Lipids Health Dis. 2024;23(1):412. https:\/\/doi.org\/10.1186\/s12944-024-02403-7","journal-title":"Lipids Health Dis"},{"issue":"11","key":"2470_CR32","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.3390\/antiox13111315","volume":"13","author":"JF Hejtmancik","year":"2024","unstructured":"Hejtmancik JF. Oxidative stress in genetic cataract formation. Antioxid (Basel). 2024;13(11):1315. https:\/\/doi.org\/10.3390\/antiox13111315.","journal-title":"Antioxid (Basel)"},{"issue":"1","key":"2470_CR33","doi-asserted-by":"publisher","first-page":"2420563","DOI":"10.1080\/13510002.2024.2420563","volume":"29","author":"W Liu","year":"2024","unstructured":"Liu W, Pan Y. Unraveling the mechanisms underlying diabetic cataracts: insights from mendelian randomization analysis. Redox Report: Commun free Radical Res. 2024;29(1):2420563. https:\/\/doi.org\/10.1080\/13510002.2024.2420563","journal-title":"Redox Report: Commun free Radical Res"},{"key":"2470_CR34","doi-asserted-by":"publisher","first-page":"108281","DOI":"10.1016\/j.compbiolchem.2024.108281","volume":"114","author":"AB Chavhan","year":"2025","unstructured":"Chavhan AB, Kola H, Bobba B, Verma YK, Verma MK. In-silico study and in-vitro validations for an affinity of mangiferin with aldose reductase: investigating potential in tackling diabetic retinopathy. Comput Biol Chem. 2025;114:108281. https:\/\/doi.org\/10.1016\/j.compbiolchem.2024.108281","journal-title":"Comput Biol Chem"},{"key":"2470_CR35","doi-asserted-by":"publisher","unstructured":"Li Y, Pan AP, Yu AY. (2024). Recent Progression of Pathogenesis and Treatment for Diabetic Cataracts. Seminars in ophthalmology, 1\u20138. Advance online publication. https:\/\/doi.org\/10.1080\/08820538.2024.2427789","DOI":"10.1080\/08820538.2024.2427789"},{"key":"2470_CR36","doi-asserted-by":"publisher","first-page":"1035105","DOI":"10.3389\/fcvm.2022.1035105","volume":"9","author":"IF Muhammad","year":"2023","unstructured":"Muhammad IF, Bao X, Nilsson PM, Zaigham S. Triglyceride-glucose (TyG) index is a predictor of arterial stiffness, incidence of diabetes, cardiovascular disease, and all-cause and cardiovascular mortality: a longitudinal two-cohort analysis. Front Cardiovasc Med. 2023;9:1035105. https:\/\/doi.org\/10.3389\/fcvm.2022.1035105","journal-title":"Front Cardiovasc Med"},{"issue":"1","key":"2470_CR37","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1186\/s12944-020-01403-7","volume":"19","author":"X Li","year":"2020","unstructured":"Li X, Li G, Cheng T, Liu J, Song G, Ma H. Association between triglyceride-glucose index and risk of incident diabetes: a secondary analysis based on a Chinese cohort study: TyG index and incident diabetes. Lipids Health Dis. 2020;19(1):236. https:\/\/doi.org\/10.1186\/s12944-020-01403-7","journal-title":"Lipids Health Dis"},{"key":"2470_CR38","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-024-02391-1","author":"C Gong","year":"2024","unstructured":"Gong C, Chen C, Zhao Y, Wang Y, Li K, Lv X, Guo X, Ma D, Zhai X, Han M, Fu S, Liu J. Interaction and combined effect of triglyceride-glucose index and hypertension on type 2 diabetes individuals\u2019 peripheral arterial disease risk. Acta Diabetol. 2024. https:\/\/doi.org\/10.1007\/s00592-024-02391-1. Advance online publication.","journal-title":"Acta Diabetol"}],"container-title":["Lipids in Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12944-025-02470-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12944-025-02470-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12944-025-02470-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T14:55:13Z","timestamp":1739544913000},"score":1,"resource":{"primary":{"URL":"https:\/\/lipidworld.biomedcentral.com\/articles\/10.1186\/s12944-025-02470-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,14]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["2470"],"URL":"https:\/\/doi.org\/10.1186\/s12944-025-02470-4","relation":{},"ISSN":["1476-511X"],"issn-type":[{"value":"1476-511X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,14]]},"assertion":[{"value":"5 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All participants submitted written informed consent and were approved by the National Ethics Board.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"48"}}