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The acute effects of cardiac interventions or cardiac surgery on global and longitudinal RV function are not entirely understood. In this study, acute changes of RV function during mitral valve surgery (MVS), percutaneous mitral valve repair (PMVR) and off-pump coronary artery bypass surgery (OPCAB) were investigated employing 3D echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty patients scheduled for MVS, 23 patients scheduled for PMVR and 25 patients scheduled for OPCAB were included retrospectively if patients had received 3D transesophageal echocardiography before and immediately after MVS, PMVR or OPCAB, respectively. RV global and longitudinal function was assessed using a 3D multiparameter set consisting of global right ventricular ejection fraction (RVEF), tricuspid annular plane systolic excursion (TAPSE), longitudinal contribution to RVEF (RVEF<jats:sub>long<\/jats:sub>) and free wall longitudinal strain (FWLS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Longitudinal RV function was significantly depressed immediately after MVS, as reflected by all parameters (RVEF<jats:sub>long<\/jats:sub>: 20\u2009\u00b1\u20095% vs. 13\u2009\u00b1\u20096%,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009\u00a00.001, TAPSE: 13.1\u2009\u00b1\u20095.1\u2009mm vs. 11.0\u2009\u00b1\u20093.5\u2009mm,<jats:italic>p<\/jats:italic>\u2009=\u20090.04 and FWLS: \u221220.1\u2009\u00b1\u20097.1% vs. -15.4\u2009\u00b1\u20095.1%, p\u2009&lt;\u2009\u00a00.001, respectively). The global RVEF was slightly impaired, but the difference did not reach significance (37\u2009\u00b1\u200913% vs. 32\u2009\u00b1\u20099%,<jats:italic>p<\/jats:italic>\u2009=\u20090.15). In the PMVR group, both global and longitudinal RV function parameters were unaltered, whereas the OPCAB group showed a slight reduction of RVEF<jats:sub>long<\/jats:sub>only (18\u2009\u00b1\u20097% vs. 14\u2009\u00b1\u20095%,<jats:italic>p<\/jats:italic>\u2009&lt;\u2009\u00a00.01). RVEF<jats:sub>long<\/jats:sub>yielded moderate case-to-case but good overall reproducibility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TAPSE, FWLS and RVEF<jats:sub>long<\/jats:sub>reflect the depression of longitudinal compared to global RV function initially after MVS. PMVR alone had no impact, while OPCAB had a slight impact on longitudinal RV function. The prognostic implications of these phenomena remain unclear and require further investigation.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12947-020-00218-x","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T17:04:10Z","timestamp":1597251850000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Acute changes of global and longitudinal right ventricular function: an exploratory analysis in patients undergoing open-chest mitral valve surgery, percutaneous mitral valve repair and off-pump coronary artery bypass grafting"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5810-8845","authenticated-orcid":false,"given":"Marius","family":"Keller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Heller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Lang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Patzelt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juergen","family":"Schreieck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Schlensak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Rosenberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry","family":"Magunia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,12]]},"reference":[{"issue":"7","key":"218_CR1","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/j.echo.2013.03.021","volume":"26","author":"J Ternacle","year":"2013","unstructured":"Ternacle J, Berry M, Cognet T, Kloeckner M, Damy T, Monin JL, et al. 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The ethics committee of the University Clinic of Ruprecht-Karls-University Tuebingen approved the retrospective enrollment of these cohorts (IRB #350\/2015R) and by legislation no patient consent is required for this study type. PMVR patients between July 2015 and April 2016 were included prospectively and informed consent was given prior to enrollment (IRB #260\/2015R).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"32"}}