{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T02:30:20Z","timestamp":1770777020921,"version":"3.50.0"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["92159203, 82471976, 82071870"],"award-info":[{"award-number":["92159203, 82471976, 82071870"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82472039"],"award-info":[{"award-number":["82472039"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Explorer Program of the Science and Technology Commission of Shanghai Municipality","award":["24TS1415300"],"award-info":[{"award-number":["24TS1415300"]}]},{"DOI":"10.13039\/501100013105","name":"Shanghai Rising-Star Program","doi-asserted-by":"publisher","award":["22QA1406000"],"award-info":[{"award-number":["22QA1406000"]}],"id":[{"id":"10.13039\/501100013105","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Nanobiotechnol"],"DOI":"10.1186\/s12951-025-03530-8","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T05:09:56Z","timestamp":1750223396000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Human serum albumin-based KBiF4@HSA nanoclusters for dual-energy computed tomography and glutathione-scavenging radiotherapy of breast cancer"],"prefix":"10.1186","volume":"23","author":[{"given":"Yuelin","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenghai","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanhuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ningxin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weixi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dengbin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Defan","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"3530_CR1","doi-asserted-by":"publisher","first-page":"106535","DOI":"10.1016\/j.intimp.2020.106535","volume":"84","author":"K Barzaman","year":"2020","unstructured":"Barzaman K, Karami J, Zarei Z, Hosseinzadeh A, Kazemi MH, Moradi-Kalbolandi S, Safari E. Farahmand, breast cancer: biology, biomarkers, and treatments. Int Immunopharmacol. 2020l;84:106535.","journal-title":"Int Immunopharmacol"},{"key":"3530_CR2","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1148\/radiol.2018172171","volume":"287","author":"K Pinker","year":"2018","unstructured":"Pinker K, Chin J, Melsaether AN, Morris EA, Moy L. Precision medicine and radiogenomics in breast cancer: new approaches toward diagnosis and treatment. Radiology. 2018;287:732\u201347.","journal-title":"Radiology"},{"key":"3530_CR3","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1245\/s10434-015-4403-9","volume":"22","author":"V Dialani","year":"2015","unstructured":"Dialani V, Chadashvili T, Slanetz PJ. Role of imaging in neoadjuvant therapy for breast cancer. Ann Surg Oncol. 2015;22:24\u20131416.","journal-title":"Ann Surg Oncol"},{"key":"3530_CR4","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.diii.2022.11.003","volume":"104","author":"J Greffier","year":"2023","unstructured":"Greffier J, Villani N, Defez D, Dabli D, Si-Mohamed S. Spectral CT imaging: technical principles of dual-energy CT and multi-energy photon-counting CT. Diagn Interv Imaging. 2023;104:167\u201377.","journal-title":"Diagn Interv Imaging"},{"key":"3530_CR5","doi-asserted-by":"publisher","first-page":"86","DOI":"10.3348\/kjr.2020.0144","volume":"22","author":"A So","year":"2021","unstructured":"So A, Nicolaou S. Spectral computed tomography: fundamental principles and recent developments. Korean J Radiol. 2021;22:86\u201396.","journal-title":"Korean J Radiol"},{"key":"3530_CR6","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1148\/radiol.2015142631","volume":"276","author":"CH McCollough","year":"2015","unstructured":"McCollough CH, Leng S, Yu L, Fletcher JG. Dual- and Multi-Energy CT: principles, technical approaches, and clinical approaches. Radiology. 2015;276:53\u2013637.","journal-title":"Radiology"},{"key":"3530_CR7","doi-asserted-by":"publisher","first-page":"1250360","DOI":"10.7150\/thno.79625","volume":"13","author":"Z Jiang","year":"2023","unstructured":"Jiang Z, Zhang M, Li P, Wang Y. Fu. Nanomaterial-based CT contrast agents and their applications in image-guided therapy. Theranostics. 2023;13:1250360.","journal-title":"Theranostics"},{"key":"3530_CR8","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1124\/jpet.119.257337","volume":"370","author":"DB Ward","year":"2019","unstructured":"Ward DB, Valentovic MA. Contrast induced acute kidney injury and direct cytotoxicity of iodinated Radiocontrast media on renal proximal tubule cells. J Pharmacol Exp Ther. 2019;370:60\u2013171.","journal-title":"J Pharmacol Exp Ther"},{"key":"3530_CR9","doi-asserted-by":"publisher","first-page":"e2114851119","DOI":"10.1073\/pnas.2114851119","volume":"119","author":"R Zhang","year":"2022","unstructured":"Zhang R, Yang Y, Dong W, Lin M, He J, Zhang X, Tian T, Yang Y, Chen K, Lei Q, Zhang S, Xu Y, Lv L. D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1. Proc Natl Acad Sci U S A. 2022;119:e2114851119.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3530_CR10","doi-asserted-by":"publisher","first-page":"e1901819","DOI":"10.1002\/adhm.201901819","volume":"9","author":"M Lyu","year":"2020","unstructured":"Lyu M, Zhu D, Kong X, Yang Y, Ding S, Zhou Y, Quan H, Duo Y, Bao Z. Glutathione-Depleting nanoenzyme and glucose oxidase combination for hypoxia modulation and radiotherapy enhancement. Adv Healthc Mater. 2020;9:e1901819.","journal-title":"Adv Healthc Mater"},{"key":"3530_CR11","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/j.ijbiomac.2022.03.139","volume":"15","author":"Q Liu","year":"2022","unstructured":"Liu Q, Ding X, Xu X, Lai H, Zeng Z, Shan T, Zhang T, Chen M, Huang Y, Huang Z, Dai X, Xia M. Cui. Tumor-targeted hyaluronic acid-based oxidative stress nanoamplifier with ROS generation and GSH depletion for antitumor therapy. Int J Biol Macromol. 2022;15:771\u201383.","journal-title":"Int J Biol Macromol"},{"key":"3530_CR12","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.actbio.2022.03.038","volume":"144","author":"S Xu","year":"2022","unstructured":"Xu S, Chang L, Zhao X, Hu Y, Lin Y, Chen Z, Ren X, Mei X. Preparation of Epigallocatechin gallate decorated Au-Ag nano-heterostructures as NIR-sensitive nano-enzymes for the treatment of osteoarthritis through mitochondrial repair and cartilage protection. Acta Biomater. 2022;144:168\u201382.","journal-title":"Acta Biomater"},{"key":"3530_CR13","doi-asserted-by":"publisher","first-page":"13195","DOI":"10.1021\/acsnano.3c00048","volume":"17","author":"L Zheng","year":"2023","unstructured":"Zheng L, Ding S, Cao Y, Li C, Zhao B, Ma Z, Zhou J, Hu Y, Zhang X, Yang Y, Duan G, Bian X. Tian. A MOF-Based potent ferroptosis inducer for enhanced radiotherapy of triple negative breast Cancer. ACS Nano. 2023;17:13195\u2013210.","journal-title":"ACS Nano"},{"key":"3530_CR14","doi-asserted-by":"publisher","first-page":"e2200194","DOI":"10.1002\/marc.202200194","volume":"43","author":"J Lin","year":"2022","unstructured":"Lin J, Yin M, Liu X, Meng F, Luo L. Nanomaterials based on functional polymers for sensitizing Cancer radiotherapy. Macromol Rapid Commun. 2022;43:e2200194.","journal-title":"Macromol Rapid Commun"},{"key":"3530_CR15","doi-asserted-by":"publisher","first-page":"8060","DOI":"10.1007\/s00330-021-07886-x","volume":"31","author":"TC Soesbe","year":"2021","unstructured":"Soesbe TC, Xi Y, Nasr K, Leyendecker JR, Lenkinski RE, Lewis MA. Investigating new CT contrast agents: a Phantom study exploring quantification and differentiation methods for high-Z elements using dual-energy CT. Eur Radiol. 2021;31:8060\u20137.","journal-title":"Eur Radiol"},{"key":"3530_CR16","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.3390\/ph16101463","volume":"16","author":"MY Ahmad","year":"2023","unstructured":"Ahmad MY, Liu S, Tegafaw T, A.K.A. A. S, D.Zhao Y, Liu SW, Nam Y, Chang GH. Lee. Mohammad Yaseen ahmad, heavy Metal-Based nanoparticles as High-Performance X-ray computed tomography contrast agents. Pharmaceuticals (Basel). 2023;16:1463.","journal-title":"Pharmaceuticals (Basel)"},{"key":"3530_CR17","doi-asserted-by":"publisher","first-page":"112546","DOI":"10.1016\/j.msec.2021.112546","volume":"134","author":"Y Chang","year":"2022","unstructured":"Chang Y, Bai Q, Wang M, Ma Y, Yu K, Lu H, Lu T, Lin H, Qu F. Plasmonic Bi nanoparticles encapsulated by N-Carbon for dual-imaging and photothermal\/photodynamic\/chemo-therapy. Biomater Adv. 2022;134:112546.","journal-title":"Biomater Adv"},{"key":"3530_CR18","doi-asserted-by":"publisher","first-page":"14355","DOI":"10.1021\/acs.langmuir.2c02474","volume":"38","author":"X Zhang","year":"2022","unstructured":"Zhang X, Liu B, Yao S, Liu Z, Li J. Multifunctional Bi nss@bsa nanoplatform guided by CT imaging for effective photothermal therapy. Langmuir. 2022;38:14355\u201363.","journal-title":"Langmuir"},{"key":"3530_CR19","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1021\/acsami.7b17838","volume":"10","author":"S Yang","year":"2018","unstructured":"Yang S, Li Z, Wang Y, Fan X, Miao Z, Hu Y, Li Z, Sun Y. Multifunctional Bi@PPy-PEG Core-Shell nanohybrids for Dual-Modal imaging and photothermal therapy. ACS Appl Mater Interfaces. 2018;10:1605\u201315.","journal-title":"ACS Appl Mater Interfaces"},{"key":"3530_CR20","doi-asserted-by":"publisher","first-page":"e2303147","DOI":"10.1002\/adhm.202303147","volume":"13","author":"T Hu","year":"2024","unstructured":"Hu T, Jia L, Li H, Yang C, Yan Y, Lin H, Zhang F, Qu F, Guo W. An intelligent and soluble microneedle composed of Bi\/BiVO4 Schottky heterojunction for tumor Ct imaging and starvation\/gas Therapy-Promoted synergistic Cancer treatment. Adv Healthc Mater. 2024;13:e2303147.","journal-title":"Adv Healthc Mater"},{"key":"3530_CR21","doi-asserted-by":"publisher","first-page":"119835","DOI":"10.1016\/j.biomaterials.2020.119835","volume":"237","author":"C Zhang","year":"2020","unstructured":"Zhang C, Li D, Pei P, Wang W, Chen B, Chu Z, Zha Z, Yang X, Wang J. Qian. Rod-based urchin-like Hollow microspheres of Bi2S3: facile synthesis, photo-controlled drug release for photoacoustic imaging and chemo-photothermal therapy of tumor ablation. Biomaterials. 2020;237:119835.","journal-title":"Biomaterials"},{"key":"3530_CR22","doi-asserted-by":"publisher","first-page":"11145","DOI":"10.1021\/acsnano.6b06067","volume":"10","author":"F Mao","year":"2016","unstructured":"Mao F, Wen L, Sun C, Zhang S, Wang G, Zeng J, Wang Y, Ma J, Gao M, Li Z. Ultrasmall biocompatible Bi2Se3 nanodots for multimodal Imaging-Guided synergistic radiophotothermal therapy against Cancer. ACS Nano. 2016;10:11145\u201355.","journal-title":"ACS Nano"},{"key":"3530_CR23","doi-asserted-by":"publisher","first-page":"9885","DOI":"10.1007\/s12274-023-5775-y","volume":"16","author":"Y Li","year":"2023","unstructured":"Li Y, Tan X, Wang H, Ji X, Fu Z, Zhang K, Su W. Ji. Zhang, D. Ni. Spectral computed tomography-guided photothermal therapy of osteosarcoma by bismuth sulfide nanorods. Nano Res. 2023;16:9885\u201393.","journal-title":"Nano Res"},{"key":"3530_CR24","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1002\/chem.201904586","volume":"26","author":"S Zhao","year":"2020","unstructured":"Zhao S, Tian R, Shao B, Feng Y, Yuan S, Dong L, Zhang L, Wang Z, You H. UCNP-Bi2 Se3 upconverting nanohybrid for upconversion luminescence and CT imaging and photothermal therapy. Chemistry. 2020;26:1127\u201335.","journal-title":"Chemistry"},{"key":"3530_CR25","doi-asserted-by":"publisher","first-page":"3025","DOI":"10.1039\/C9BM00351G","volume":"7","author":"L Sun","year":"2019","unstructured":"Sun L, Li Q, Zhang L, Chai H, Yu L, Xu Z, Kang Y. Xue. Stimuli responsive pegylated bismuth Selenide Hollow nanocapsules for fluorescence\/ct imaging and light-driven multimodal tumor therapy. Biomater Sci. 2019;7:3025\u201340.","journal-title":"Biomater Sci"},{"key":"3530_CR26","first-page":"97","volume":"10","author":"Z Li","year":"2016","unstructured":"Li Z, Hu Y, Howard KA, Jiang T, Fan X, Miao Z, Sun Y, Besenbacher F. Yu. Multifunctional bismuth Selenide nanocomposites for antitumor Thermo-Chemotherapy and imaging. ACS Nano. 2016;10:97\u2013984.","journal-title":"ACS Nano"},{"key":"3530_CR27","doi-asserted-by":"publisher","first-page":"e1900250","DOI":"10.1002\/adhm.201900250","volume":"8","author":"Y Song","year":"2019","unstructured":"Song Y, Wang Y, Zhu Y, Cheng Y, Wang Y, Wang S, Tan F, Lian F, Li N. Biomodal Tumor-Targeted and Redox-Responsive Bi2Se3 Hollow nanocubes for MSOT\/CT imaging guided synergistic Low-Temperature photothermal radiotherapy. Adv Healthc Mater. 2019;8:e1900250.","journal-title":"Adv Healthc Mater"},{"key":"3530_CR28","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.colsurfa.2019.05.033","volume":"576","author":"A Ghazanfari","year":"2019","unstructured":"Ghazanfari A, Marasini S, Miao X, Park JA, Jung K, Ahmad MY, Yue H, Ho SL, Liu S, Jang YJ, Chae KS, Chang Y, Lee GH. Synthesis, characterization, and X-ray Attenuation properties of polyacrylic acid-coated ultrasmall heavy metal oxide (Bi2O3, Yb2O3, NaTaO3, Dy2O3, and Gd2O3) nanoparticles as potential CT contrast agents. Colloids Surf. 2019;576:73\u201381.","journal-title":"Colloids Surf"},{"key":"3530_CR29","doi-asserted-by":"publisher","first-page":"26346","DOI":"10.1021\/acsami.5b09990","volume":"7","author":"PP Lei","year":"2015","unstructured":"Lei PP, Zhang P, Yuan QH, Wang Z, Dong LL, Song SY, Xu X, Liu XL, Feng J, Zhang HJ. Yb3+\/Er3+-Codoped Bi2O3 nanospheres: probe for upconversion luminescence imaging and binary contrast agent for computed tomography imaging. ACS Appl Mater Interfaces. 2015;7:26346\u201354.","journal-title":"ACS Appl Mater Interfaces"},{"key":"3530_CR30","doi-asserted-by":"publisher","first-page":"5973","DOI":"10.2147\/IJN.S130455","volume":"12","author":"F Du","year":"2017","unstructured":"Du F, Lou J, Jiang R, Fang Z, Zhao X, Niu Y, Zou S, Zhang M, Gong A, Wu C. Hyaluronic acid-functionalized bismuth oxide nanoparticles for computed. Int J Nanomed. 2017;12:5973\u201392.","journal-title":"Int J Nanomed"},{"key":"3530_CR31","doi-asserted-by":"publisher","first-page":"124264","DOI":"10.1016\/j.ijpharm.2024.124264","volume":"659","author":"M Yektamanesh","year":"2024","unstructured":"Yektamanesh M, Ayyami Y, Ghorbani M, Dastgir M, Malekzadeh R, Mortezazadeh T. Characterization of multifunctional \u03b2-cyclodextrin-coated Bi2O3 nanoparticles conjugated with Curcumin for CT imaging-guided synergetic chemo-radiotherapy in breast cancer. Int J Pharm. 2024;659:124264.","journal-title":"Int J Pharm"},{"key":"3530_CR32","doi-asserted-by":"crossref","unstructured":"Wu S, Meng X, Jiang X, Wu Y, Zhai S, Wang X, Liu Y, Zhang J, Zhao X, Zhou Y, Bu W, Yao Z. Harnessing X-Ray Energy-Dependent Attenuation of Bismuth-Based nanoprobes for accurate diagnosis of liver fibrosis. Adv Sci (Weinh). 20121;8:e2002548.","DOI":"10.1002\/advs.202002548"},{"key":"3530_CR33","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s11671-021-03591-2","volume":"16","author":"J Xie","year":"2021","unstructured":"Xie J, Zhou Z, Ma S, Luo X, Liu J, Wang S, Chen Y, Yan J, Luo F. Facile fabrication of BiF3: Ln (Ln\u2009=\u2009Gd, yb, Er)@PVP Nanoparticles for High-Efficiency Computed Tomography Imaging. Nanoscale Res Lett. 2021;16:131.","journal-title":"Nanoscale Res Lett"},{"key":"3530_CR34","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1039\/C9NR09401F","volume":"12","author":"S Zhao","year":"2020","unstructured":"Zhao S, Tian R, Shao B, Feng Y, Yuan S, Dong L, Zhang L, Wang Z, You H. One-pot synthesis of Ln3+-doped porous BiF3@PAA nanospheres for temperature sensing and pH-responsive drug delivery guided by CT imaging. Nanoscale. 2020;12:695\u2013702.","journal-title":"Nanoscale"},{"key":"3530_CR35","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.actbio.2023.05.026","volume":"166","author":"Z Fu","year":"2023","unstructured":"Fu Z, Li K, Wang H, Li Y, Zhang J, Zhou J, Hu J, Xie D. D. N.Spectral computed tomography-guided radiotherapy of osteosarcoma utilizing bioi nanosheets. Acta Biomater. 2023;166:615\u201326.","journal-title":"Acta Biomater"},{"key":"3530_CR36","first-page":"695","volume":"12","author":"Y Zhang","year":"2020","unstructured":"Zhang Y, Wang R, Li W, Huang G, Zhu J, Cheng J, He D..Construction of DOX\/APC co-loaded bioi@cus NPs for safe and highly effective CT imaging and chemo-photothermal therapy of lung cancer. J Mater Chem B. 2020;12:695\u2013702.","journal-title":"J Mater Chem B"},{"key":"3530_CR37","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/j.ijbiomac.2022.07.094","volume":"30","author":"M Shakeri","year":"2022","unstructured":"Shakeri M, Montazerabadi HDHA. Yourdkhani. Hyaluronic acid-coated ultrasmall bioi nanoparticles as a potentially targeted contrast agent for X-ray computed tomography. Int J Biol Macromol. 2022;30:668\u201376.","journal-title":"Int J Biol Macromol"},{"key":"3530_CR38","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.biomaterials.2019.03.001","volume":"203","author":"W Liao","year":"2019","unstructured":"Liao W, Lei P, Pan J, Zhang C, Sun X, Zhang X, Yu C, Sun S. Bi-DTPA as a high-performance CT contrast agent for in vivo imaging. Biomaterials. 2019;203:1\u201311.","journal-title":"Biomaterials"},{"key":"3530_CR39","doi-asserted-by":"publisher","first-page":"122646","DOI":"10.1016\/j.biomaterials.2024.122646","volume":"311","author":"J Pan","year":"2024","unstructured":"Pan J, Wang J, Zhao Y, Han B, Shu G, Ma M, Wang X, Wei X, Hou W, Sun S. Real-time detection of Gastrointestinal leaks via bismuth chelate-enhanced X-ray gastroenterography. Biomaterials. 2024;311:122646.","journal-title":"Biomaterials"},{"key":"3530_CR40","doi-asserted-by":"publisher","first-page":"122422","DOI":"10.1016\/j.biomaterials.2023.122422","volume":"305","author":"G Shu","year":"2024","unstructured":"Shu G, Zhao L, Li F, Jiang Y, Zhang X, Yu C, Pan J, Sun S. Metallic artifacts-free spectral computed tomography angiography based on renal clearable bismuth chelate. Biomaterials. 2024;305:122422.","journal-title":"Biomaterials"},{"key":"3530_CR41","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.bbrc.2023.05.065","volume":"671","author":"Y Zhang","year":"2023","unstructured":"Zhang Y, Liu D, Qiao B, Luo Y, Yang C, Zhang L, Cao Y, Ran H. Bi-DTPA, a potential CT-guided radiation sensitizer. Biochem Biophys Res Commun. 2023;671:192\u20139.","journal-title":"Biochem Biophys Res Commun"},{"key":"3530_CR42","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1016\/j.cej.2018.06.170","volume":"351","author":"L Feng","year":"2018","unstructured":"Feng L, Yang D, Gai S, He F, Yang G, Yang P, Lin J. Single bismuth tungstate nanosheets for simultaneous chemo-, photothermal, and photodynamic therapies mediated by near-infrared light. Chem Eng J. 2018;351:1147\u201358.","journal-title":"Chem Eng J"},{"key":"3530_CR43","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1021\/acsami.7b16000","volume":"10","author":"C Zhang","year":"2018","unstructured":"Zhang C, Ren J, Hua J, Xia L, He J. Huo. Yong Hu multifunctional Bi2WO6 nanoparticles for CT-Guided photothermal and Oxygen-Free photodynamic therapy. ACS Appl Mater Interfaces. 2018;10:1132\u201346.","journal-title":"ACS Appl Mater Interfaces"},{"key":"3530_CR44","doi-asserted-by":"publisher","first-page":"18795","DOI":"10.1021\/acsomega.2c01591","volume":"7","author":"Y Hao","year":"2022","unstructured":"Hao Y, Peng B, Si C, Wang B, Luo C, Chen M, Luo C, Gong B, Li Z. PVP-Modified multifunctional Bi2WO6 nanosheets for enhanced CT imaging and Cancer radiotherapy. ACS Omega. 2022;7:18795\u2013803.","journal-title":"ACS Omega"},{"key":"3530_CR45","doi-asserted-by":"publisher","first-page":"e2309789","DOI":"10.1002\/adma.202309789","volume":"36","author":"C Wang","year":"2024","unstructured":"Wang C, Zhu J, Wang S, Zhao L, Wei P, Yi T. Self-Assembled Nano-CT contrast agent leveraging size aggregation for improved in vivo tumor CT imaging. Adv Mater. 2024;36:e2309789.","journal-title":"Adv Mater"},{"key":"3530_CR46","doi-asserted-by":"publisher","first-page":"3403","DOI":"10.1021\/acs.molpharmaceut.0c00458","volume":"17","author":"Y Ma","year":"2020","unstructured":"Ma Y, Zhang D, Peng Z, Guan S. Zhai. Delivery of Platinum(IV) prodrugs via Bi2Te3 nanoparticles for Photothermal-Chemotherapy and photothermal\/photoacoustic imaging. Mol Pharm. 2020;17:3403\u201311.","journal-title":"Mol Pharm"},{"key":"3530_CR47","doi-asserted-by":"publisher","first-page":"120453","DOI":"10.1016\/j.biomaterials.2020.120453","volume":"264","author":"F He","year":"2021","unstructured":"He F, Ji H, Feng L, Wang Z, Sun Q, Zhong C, Yang D, Gai S, Yang P, Lin J. Construction of thiol-capped ultrasmall Au-Bi bimetallic nanoparticles for X-ray CT imaging and enhanced antitumor therapy efficiency. Biomaterials. 2021;264:120453.","journal-title":"Biomaterials"},{"key":"3530_CR48","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1039\/C9CS00283A","volume":"49","author":"M Shahbazi","year":"2020","unstructured":"Shahbazi M, Faghfouri L, Ferreira, M\u00f3nica PA, Figueiredo, Patr\u00edcia H, Maleki F, Sefat J, Hirvonen. Santos, H\u00e9lder A. The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties. Chem Soc Rev. 2020;49:1253\u2013321.","journal-title":"Chem Soc Rev"},{"key":"3530_CR49","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.3390\/nano10081463","volume":"10","author":"JC Bulmahn","year":"2020","unstructured":"Bulmahn JC, Tikhonowski G, Popov AA, Kuzmin A, Klimentov SM, Kabashin AV. Laser-Ablative synthesis of stable aqueous solutions of elemental bismuth nanoparticles for multimodal theranostic applications. Nanomaterials (Basel). 2020;10:1463.","journal-title":"Nanomaterials (Basel)"},{"key":"3530_CR50","first-page":"72","volume":"25","author":"JF Xu","year":"2022","unstructured":"Xu JF, Yang YS, Jiang AQ, Zhu HL. Detect Methods Res Progress Hum Serum Albumin. 2022;25:72\u201392.","journal-title":"Detect Methods Res Progress Hum Serum Albumin"},{"key":"3530_CR51","doi-asserted-by":"publisher","first-page":"10245","DOI":"10.1021\/acsnano.6b05760","volume":"10","author":"W Yang","year":"2016","unstructured":"Yang W, Guo W, Le W, Lv. G, Zhang. F, Shi. L, Wang X, Wang J. Wang. J. Chang. B. Zhang. Albumin-Bioinspired gd:cus nanotheranostic agent for in vivo photoacoustic\/magnetic resonance Imaging-Guided Tumor-Targeted photothermal therapy. ACS Nano. 2016;10:10245\u201357.","journal-title":"ACS Nano"},{"key":"3530_CR52","doi-asserted-by":"publisher","first-page":"120186","DOI":"10.1016\/j.biomaterials.2020.120186","volume":"255","author":"W Yang","year":"2022","unstructured":"Yang W, Xiang C, Xu Y, Chen S, Zeng W, Liu K, Jin X, Zhou X, Zhang B. Albumin-constrained large-scale synthesis of renal clearable ferrous sulfide quantum Dots for T1-Weighted MR imaging and phototheranostics of tumors. Biomaterials. 2022;255:120186.","journal-title":"Biomaterials"},{"key":"3530_CR53","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.ejpb.2022.12.016","volume":"183","author":"L Xiang","year":"2023","unstructured":"Xiang L, Fang C, Feng J, Tan Y, Wu Q, Zhou X, Li J, Gong T. P palmitic acid-modified human serum albumin Paclitaxel nanoparticles targeting tumor and macrophages against breast cancer. Eur J Pharm Biopharm. 2023;183:132\u201341.","journal-title":"Eur J Pharm Biopharm"},{"key":"3530_CR54","doi-asserted-by":"publisher","first-page":"10040","DOI":"10.1021\/acs.nanolett.2c03763","volume":"22","author":"Z Wang","year":"2022","unstructured":"Wang Z, Liu Y, Li S, Meng F, Yu J, Zhou S, Dong S, Ye J, Li L, Zhang C, Qiu S, Lin G, Liu H, Li S, He Z, Wang Y. Bioinspired nanocomplexes comprising phenolic acid derivative and human serum albumin for Cancer therapy. Nano Lett. 2022;22:10040\u20138.","journal-title":"Nano Lett"},{"key":"3530_CR55","first-page":"1088","volume":"30","author":"NR Vysyaraju","year":"2022","unstructured":"Vysyaraju NR, Paul M, Ch S, Ghosh B, Biswas S. Olaparib@human serum albumin nanoparticles as sustained drug-releasing tumour-targeting nanomedicine to inhibit growth and metastasis in the mouse model of triple-negative breast cancer. J Drug Target. 2022;30:1088\u2013105.","journal-title":"J Drug Target"},{"key":"3530_CR56","doi-asserted-by":"publisher","first-page":"125066","DOI":"10.1016\/j.cej.2020.125066","volume":"395","author":"X Wang","year":"2022","unstructured":"Wang X, Hu Y, Wang R, Zhao P, Gu W, Ye L. Albumin-mediated synthesis of fluoroperovskite KMnF3 nanocrystals for T1-T2 dual-modal magnetic resonance imaging of brain gliomas with improved sensitivity. Chem Eng J. 2022;395:125066.","journal-title":"Chem Eng J"},{"key":"3530_CR57","doi-asserted-by":"publisher","first-page":"7873","DOI":"10.1021\/acs.jctc.3c00720","volume":"19","author":"DR McCarthy","year":"2023","unstructured":"McCarthy DR, Remington JM, Ferrell JB, Schneebeli ST, Li J. Nano-Bio interactions between DNA nanocages and human serum albumin. J Chem Theory Comput. 2023;19:7873\u201381.","journal-title":"J Chem Theory Comput"},{"key":"3530_CR58","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.1021\/acs.molpharmaceut.1c00046","volume":"18","author":"A Spada","year":"2021","unstructured":"Spada A, Emami J, Tuszynski JA, Lavasanifar A. The uniqueness of albumin as a carrier in nanodrug delivery. Mol Pharm. 2021;18:1862\u201394.","journal-title":"Mol Pharm"},{"key":"3530_CR59","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.ijbiomac.2020.04.130","volume":"159","author":"Z Hasanpoor","year":"2020","unstructured":"Hasanpoor Z, Mostafaie A, Nikokar I, Hassan ZM. Curcumin-human serum albumin nanoparticles decorated with PDL1 binding peptide for targeting PDL1-expressing breast cancer cells. Int J Biol Macromol. 2020;159:137\u201353.","journal-title":"Int J Biol Macromol"},{"key":"3530_CR60","doi-asserted-by":"publisher","first-page":"834","DOI":"10.3390\/antiox12040834","volume":"12","author":"H\u00e9ctor V\u00e1zquez-Meza","year":"2023","unstructured":"V\u00e1zquez-Meza H\u00e9ctor, Magdalena V-LMar\u00eda. V\u00e1zquez-Carrada, melissa, Uribe-Ram\u00edrez, daniel, D. Matuz-Mares. Cellular compartmentalization, glutathione transport and its relevance in some pathologies. Antioxid (Basel). 2023;12:834.","journal-title":"Antioxid (Basel)"}],"container-title":["Journal of Nanobiotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12951-025-03530-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12951-025-03530-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12951-025-03530-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T06:02:16Z","timestamp":1750226536000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03530-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":60,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3530"],"URL":"https:\/\/doi.org\/10.1186\/s12951-025-03530-8","relation":{},"ISSN":["1477-3155"],"issn-type":[{"value":"1477-3155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,18]]},"assertion":[{"value":"17 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The ethical review board of the XinHua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, China, approved the experiment protocol and strictly followed its guidelines (Ethical approval number: XHEC-F-2024-014).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All authors read and agreed to submit the manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"451"}}