{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:10:56Z","timestamp":1790647856271,"version":"4.1.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["KO 3552\/4-"],"award-info":[{"award-number":["KO 3552\/4-"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Negat Results BioMed"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12952-017-0067-2","type":"journal-article","created":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T12:31:11Z","timestamp":1486038671000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Antimicrobial activity of HL-60 cells compared to primary blood-derived neutrophils against Staphylococcus aureus"],"prefix":"10.1186","volume":"16","author":[{"given":"Ragheda","family":"Yaseen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Blodkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"L\u00fcthje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Reuner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"V\u00f6llger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan Y.","family":"Naim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"von K\u00f6ckritz-Blickwede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,2,19]]},"reference":[{"key":"67_CR1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1083\/JCB1842OIA5","volume":"184","author":"Y Wang","year":"2009","unstructured":"Wang Y, Li M, Stadler S, Correll S, Li P, Wang D, et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol. 2009;184:5\u2013213.","journal-title":"J Cell Biol"},{"key":"67_CR2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0960-0760(95)00089-I","volume":"53","author":"A Verstuyf","year":"1995","unstructured":"Verstuyf A, Mathieu C, Verlinden L, Waer M, Tan BK, Bouillon R. Differentiation Induction of Human Leukemia Cells (HL60) by a Combination of 1, 25-Dihydroxyvitamin D3 and Retinoic Acid (All Trans or 9-Cis). Steroid Biochem Molec Biol. 1995;53:431\u201341.","journal-title":"Steroid Biochem Molec Biol"},{"key":"67_CR3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1532\/IJH97.A10407","volume":"81","author":"LL An","year":"2005","unstructured":"An LL, Ma XT, Yang YH, Lin YM, Song YH, Wu KF. Marked reduction of LL-37\/hCAP-18, an antimicrobial peptide, in patients with acute myeloid leukemia. Int J Hematol. 2005;81:45\u20137.","journal-title":"Int J Hematol"},{"key":"67_CR4","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1182\/blood.V87.1.350.350","volume":"87","author":"S Herwig","year":"1996","unstructured":"Herwig S, Su Q, Zhang W, Ma Y, Tempst P. Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells. Blood. 1996;87:350\u201364.","journal-title":"Blood"},{"key":"67_CR5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1371\/journal.pone.0007363","volume":"4","author":"P Nordenfelt","year":"2009","unstructured":"Nordenfelt P, Bauer S, Lonnbro P, Tapper H. Phagocytosis of Streptococcus pyogenes by all-trans retinoic acid-differentiated HL-60 cells: roles of azurophilic granules and NADPH oxidase. PLoS ONE. 2009;4:10.","journal-title":"PLoS ONE"},{"key":"67_CR6","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/nri1785","volume":"6","author":"C Nathan","year":"2006","unstructured":"Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol. 2006;6:173\u201382.","journal-title":"Nat Rev Immunol"},{"key":"67_CR7","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","volume":"303","author":"V Brinkmann","year":"2004","unstructured":"Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, et al. Neutrophil extracellular traps kill bacteria. Science. 2004;303:1532\u201335.","journal-title":"Science"},{"key":"67_CR8","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00109-009-0481-0","volume":"87","author":"M Von K\u00f6ckritz-Blickwede","year":"2009","unstructured":"Von K\u00f6ckritz-Blickwede M, Nizet V. Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps. J Mol Med. 2009;87:775\u201383.","journal-title":"J Mol Med"},{"key":"67_CR9","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.meegid.2013.04.030","volume":"21","author":"AC Uhlemann","year":"2013","unstructured":"Uhlemann AC, Otto M, Lowy FD, DeLeo FR. Evolution of community- and healthcare-associated methicillin-resistant Staphylococcus aureus. Infect Genet Evol. 2013;21:563\u201374.","journal-title":"Infect Genet Evol"},{"key":"67_CR10","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-micro-092412-155711","volume":"68","author":"CY Okumura","year":"2014","unstructured":"Okumura CY, Nizet V. Subterfuge and sabotage: evasion of host innate defenses by invasive gram-positive bacterial pathogens. Annu Rev Microbiol. 2014;68:439\u201358.","journal-title":"Annu Rev Microbiol"},{"key":"67_CR11","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1159\/000319909","volume":"2","author":"ET Berends","year":"2010","unstructured":"Berends ET, Horswill AR, Haste NM, Monestier M, Nizet V, Von K\u00f6ckritz-Blickwede M. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J Innate Immun. 2010;2:576\u201386.","journal-title":"J Innate Immun"},{"key":"67_CR12","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1476-9255-7-26","volume":"7","author":"L Wang","year":"2010","unstructured":"Wang L, Learoyd J, Duan Y, Leff AR, Zhu X. Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells. J Inflamm. 2010;7:26.","journal-title":"J Inflamm"},{"key":"67_CR13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1126\/science.1101400","volume":"306","author":"Y Wang","year":"2004","unstructured":"Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, et al. Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination. Science. 2004;306:279\u201383.","journal-title":"Science"},{"key":"67_CR14","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.4049\/jimmunol.148.5.1561","volume":"148","author":"MJ Losman","year":"1992","unstructured":"Losman MJ, Fasy TM, Novick KE, Monestier M. Monoclonal autoantibodies to subnucleosomes from a MRL\/Mp(\u2212)+\/+ mouse. Oligoclonality of the antibody response and recognition of a determinant composed of histones H2A, H2B, and DNA. J Immunol. 1992;148:1561\u201369.","journal-title":"J Immunol"},{"key":"67_CR15","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.4049\/jimmunol.1302286","volume":"192","author":"L Vong","year":"2014","unstructured":"Vong L, Lorentz RJ, Assa A, Glogauer M, Sherman PM. Probiotic Lactobacillus rhamnosus inhibits the formation of neutrophil extracellular traps. J Immunol. 2014;192:1870\u20137.","journal-title":"J Immunol"},{"key":"67_CR16","first-page":"1","volume":"9","author":"T Kawakami","year":"2014","unstructured":"Kawakami T, He J, Morita H, Yokoyama K, Kaji H, Tanaka C, et al. Rab27a is essential for the formation of neutrophil extracellular traps (NETs) in neutrophil-like differentiated HL60 cells. PLoS ONE. 2014;9:1.","journal-title":"PLoS ONE"},{"key":"67_CR17","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1182\/blood-2012-01-405993","volume":"120","author":"AM McInturff","year":"2012","unstructured":"McInturff AM, Cody MJ, Elliott EA, Glenn JW, Rowley JW, Rondina MT, Yost CC. Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 alpha. Blood. 2012;120:3118\u201325.","journal-title":"Blood"},{"key":"67_CR18","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1083\/jcb.200606027","volume":"176","author":"TA Fuchs","year":"2007","unstructured":"Fuchs TA, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol. 2007;176:231\u201341.","journal-title":"J Cell Biol"},{"issue":"12","key":"67_CR19","doi-asserted-by":"crossref","first-page":"7413","DOI":"10.4049\/jimmunol.1000675","volume":"185","author":"FH Pilsczek","year":"2010","unstructured":"Pilsczek FH, Salina D, Poon KK, Fahey C, Yipp BG, Sibley CD, et al. A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus. J Immunol. 2010;185(12):7413\u201325.","journal-title":"J Immunol"},{"key":"67_CR20","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1083\/jcb.201006052","volume":"191","author":"V Papayannopoulos","year":"2010","unstructured":"Papayannopoulos V, Metzler KD, Hakkim A, Zychlinsky A. Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J Cell Biol. 2010;191:677\u201391.","journal-title":"J Cell Biol"}],"container-title":["Journal of Negative Results in BioMedicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12952-017-0067-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T01:33:39Z","timestamp":1692668019000},"score":1,"resource":{"primary":{"URL":"http:\/\/jnrbm.biomedcentral.com\/articles\/10.1186\/s12952-017-0067-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,19]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["67"],"URL":"https:\/\/doi.org\/10.1186\/s12952-017-0067-2","relation":{},"ISSN":["1477-5751"],"issn-type":[{"value":"1477-5751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,19]]},"article-number":"2"}}