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The control group were healthy women (<jats:italic>n<\/jats:italic>\u00a0=\u2009100) and the comparison group, women with PCOS (<jats:italic>n<\/jats:italic>\u00a0=\u2009101). Data were collected by clinical Rome III criteria to determine the IBS, Bristol scale for stool consistency and IBS QOL.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The reporting of IBS symptoms were higher in PCOS (20.7%) than control group (11%) (<jats:italic>P<\/jats:italic>\u2009=\u20090.05). The IBS QOL score in the IBS\u2009+\u2009PCOS group was lower than other groups (IBS+ non PCOS, non IBS\u2009+\u2009PCOS, non IBS+ non PCOS; scores in food avoidance and worries about health domains were significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>We conclude that having PCOS and an increased level of LH\/FSH tends to cause IBS symptoms. IBS\u2009+\u2009PCOS women experience significant impaired quality of life scores particularly in relation to worries about health and food avoidance. These results offer further insights into IBS in PCOS women and their functional status and wellbeing.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12955-020-01428-7","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T10:04:06Z","timestamp":1594634646000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The impact of irritable bowel syndrome on health-related quality of life in women with polycystic ovary syndrome"],"prefix":"10.1186","volume":"18","author":[{"given":"Fatemeh","family":"Bazarganipour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed-Abdolvahab","family":"Taghavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zatollah","family":"Asemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Allan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Khashavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahereh","family":"Safarzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamsi","family":"Pourchangiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Zare","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samaneh","family":"Ghasemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zivar","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Azizi Kutenaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"issue":"7536","key":"1428_CR1","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1136\/bmj.332.7536.280","volume":"332","author":"A Agrawal","year":"2006","unstructured":"Agrawal A, Whorwell PJ. 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Study protocol was approved by the research ethics committee of Hormozgan University of Medical Sciences (HUMS). Written informed consent of all children was obtained. In addition, parental consent was obtained for all participants and the consent was also provided in written form.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"226"}}